Page last updated: 2024-10-23

baclofen and Nicotine Addiction

baclofen has been researched along with Nicotine Addiction in 7 studies

Research Excerpts

ExcerptRelevanceReference
"These results showed that nicotine rewarding properties and negative aspects of nicotine withdrawal, such as anxiety-like effects and somatic manifestations, can be modulated by the GABAB receptor activity."3.80Attenuation by baclofen of nicotine rewarding properties and nicotine withdrawal manifestations. ( Aso, E; Balerio, GN; Maldonado, R; Moutinho, LM; Varani, AP, 2014)
"Baclofen has been reported in uncontrolled clinical studies to reduce craving for abused drugs and reduce their rewarding effects."2.70Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking. ( Cousins, MS; de Wit, H; Stamat, HM, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Varani, AP3
Antonelli, MC1
Balerio, GN3
Aso, E1
Moutinho, LM1
Maldonado, R1
Fattore, L1
Spano, MS1
Cossu, G1
Scherma, M1
Fratta, W1
Fadda, P1
Daskalakis, ZJ1
George, TP1
Forget, B1
Pushparaj, A1
Le Foll, B1
Cousins, MS1
Stamat, HM1
de Wit, H1

Reviews

1 review available for baclofen and Nicotine Addiction

ArticleYear
Clozapine, GABA(B), and the treatment of resistant schizophrenia.
    Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:4

    Topics: Antipsychotic Agents; Baclofen; Clozapine; Drug Resistance; GABA Agonists; GABA Antagonists; gamma-A

2009

Trials

1 trial available for baclofen and Nicotine Addiction

ArticleYear
Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2001, Volume: 3, Issue:2

    Topics: Acute Disease; Adult; Affect; Baclofen; Dose-Response Relationship, Drug; Double-Blind Method; Femal

2001

Other Studies

5 other studies available for baclofen and Nicotine Addiction

ArticleYear
Mecamylamine-precipitated nicotine withdrawal syndrome and its prevention with baclofen: an autoradiographic study of α4β2 nicotinic acetylcholine receptors in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jul-01, Volume: 44

    Topics: Analysis of Variance; Animals; Autoradiography; Baclofen; Brain; Cholinergic Agents; Disease Models,

2013
Attenuation by baclofen of nicotine rewarding properties and nicotine withdrawal manifestations.
    Psychopharmacology, 2014, Volume: 231, Issue:15

    Topics: Animals; Anxiety; Avoidance Learning; Baclofen; Conditioning, Psychological; GABA-B Receptor Agonist

2014
Baclofen prevents drug-induced reinstatement of extinguished nicotine-seeking behaviour and nicotine place preference in rodents.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2009, Volume: 19, Issue:7

    Topics: Animals; Baclofen; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Drug Administrat

2009
Granular insular cortex inactivation as a novel therapeutic strategy for nicotine addiction.
    Biological psychiatry, 2010, Aug-01, Volume: 68, Issue:3

    Topics: Analysis of Variance; Animals; Association Learning; Baclofen; Behavior, Addictive; Behavior, Animal

2010
GABA(B) receptors involvement in the effects induced by nicotine on anxiety-related behaviour in mice.
    Pharmacological research, 2012, Volume: 65, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Baclofen; Behavior, Animal; GABA-B Receptor Agonists; GABA-B

2012