Page last updated: 2024-11-08

serine and Nicotine Addiction

serine has been researched along with Nicotine Addiction in 1 studies

Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Tapper, AR	1
McKinney, SL	1
Nashmi, R	1
Schwarz, J	1
Deshpande, P	1
Labarca, C	1
Whiteaker, P	1
Marks, MJ	1
Collins, AC	1
Lester, HA	1

Clinical Trials (1)

Trial Overview

Trial			Phase	Enrollment	Study Type	Start Date	Status
Varenicline Augmentation of Patch Outcomes in Heavy Drinkers' Smoking Cessation[NCT02859142]			Phase 4	122 participants (Actual)	Interventional	2018-03-29	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Self-Reported Alcohol Drinking Days at 12 Weeks

Self-reported alcohol drinking days obtained via a past month Timeline Followback Calendar at 12 weeks (NCT02859142)
Timeframe: 12 weeks

Intervention	days (Mean)
Augmented Treatment	12.25
Standard Treatment	11.96

Change From Baseline in Self-Reported Alcohol Drinking Days at 26 Weeks

Self reported monthly alcohol drinking days obtained via a past month Timeline Followback Calendar at 26 weeks (NCT02859142)
Timeframe: 26 weeks

Intervention	days (Mean)
Augmented Treatment	12.73
Standard Treatment	11.44

Change From Baseline in Self-Reported Heavy Drinking Days at 12 Weeks

Self reported heavy drinking (5+ drinks/day for men, 4+ drinks/day for women) days obtained via a past month Timeline Followback Calendar at 12 weeks (NCT02859142)
Timeframe: 12 weeks

Intervention	days (Mean)
Augmented Treatment	5.02
Standard Treatment	5.58

Change From Baseline in Self-Reported Heavy Drinking Days at 26 Weeks

Self reported heavy drinking (5+ drinks/day for men, 4+ drinks/day for women) days obtained via a past month Timeline Followback Calendar at 26 weeks (NCT02859142)
Timeframe: 26 weeks

Intervention	days (Mean)
Augmented Treatment	4.79
Standard Treatment	5.56

Change From Baseline Smoking Abstinence Rates at 12 Weeks

Number of participants reporting smoking abstinence at 12 weeks from baseline (smoking quit date) via subjective and biologically verified reports. (NCT02859142)
Timeframe: 12 weeks

Intervention	Participants (Count of Participants)
Augmented Treatment	27
Standard Treatment	17

Change From Baseline Smoking Abstinence Rates at 26 Weeks

Number of participants reporting smoking abstinence at 26 weeks from quit date via subjective and biologically verified reports. (NCT02859142)
Timeframe: 26 weeks

Intervention	Participants (Count of Participants)
Augmented Treatment	15
Standard Treatment	16

Other Studies

1 other study available for serine and Nicotine Addiction

Article	Year
Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization. Science (New York, N.Y.), 2004, Nov-05, Volume: 306, Issue:5698 Topics: Alkaloids; Animals; Azocines; Brain; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Cells, Cultur	2004