Page last updated: 2024-11-04

sodium fluoride and Vascular Calcification

sodium fluoride has been researched along with Vascular Calcification in 30 studies

Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.

Research Excerpts

ExcerptRelevanceReference
" In patients with diabetes mellitus, arterial calcification is accelerated and calcification activity can be detected using 18F-sodium fluoride positron emission tomography (18F-NaF PET)."5.51The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial. ( Bellinge, JW; Bondonno, NP; Francis, RJ; Lee, SC; Lewis, JR; Schultz, CJ; Sim, M; Watts, GF, 2022)
" Fluorine 18−Sodium Fluoride (18F-NaF) PET/CT can be used as a sensitive imaging modality for detection of vascular calcification."4.12Atherogenic Indices as a Predictor of Aortic Calcification in Prostate Cancer Patients Assessed Using ( Anabaraonye, N; Chatterjee, S; Chesnais, H; Dai, M; Parente, J; Rajapakse, CS; Xu, W, 2022)
"The rabbits were divided into 2 groups as follows: an atherosclerosis group (n = 10) and an atorvastatin group (n = 10)."4.02Atorvastatin Promotes Macrocalcification, But Not Microcalcification in Atherosclerotic Rabbits: An 18F-NaF PET/CT Study. ( Chen, X; Liang, Z; Nie, M; Yan, Y; Zhang, X; Zhao, Q, 2021)
"The identification of the vulnerable atheroma plaque could allow a more effective treatment of cerebrovascular accident (CVA)."1.43New insight of functional molecular imaging into the atheroma biology: 18F-NaF and 18F-FDG in symptomatic and asymptomatic carotid plaques after recent CVA. Preliminary results. ( Banzo, I; Carril, JM; Ibáñez-Bravo, S; Jiménez-Alonso, M; Jiménez-Bonilla, J; López-Defilló, J; Martínez-Amador, N; Martínez-Rodríguez, I; Quirce, R; Revilla, MA, 2016)
"Vascular calcification is a complex biological process that is a hallmark of atherosclerosis."1.42Identifying active vascular microcalcification by (18)F-sodium fluoride positron emission tomography. ( Bennett, MR; Bird, JL; Brindle, KM; Davenport, AP; Dweck, MR; Gallagher, FA; Irkle, A; Joshi, FR; Lewis, DY; Newby, DE; Rudd, JH; Skepper, JN; Vesey, AT; Warburton, EA, 2015)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's20 (66.67)24.3611
2020's10 (33.33)2.80

Authors

AuthorsStudies
Bellinge, JW2
Francis, RJ2
Lee, SC1
Bondonno, NP1
Sim, M1
Lewis, JR1
Watts, GF2
Schultz, CJ2
Zhang, X1
Chen, X1
Liang, Z1
Nie, M1
Yan, Y1
Zhao, Q1
Yang, W1
Zhong, Z1
Feng, G1
Wang, Z1
Dai, M1
Xu, W1
Chesnais, H1
Anabaraonye, N1
Parente, J1
Chatterjee, S1
Rajapakse, CS1
Bing, R1
Dweck, MR8
Toczek, J1
Kwiecinski, J1
Slomka, PJ1
Newby, DE6
Berman, DS1
Tzolos, E1
Kaiser, Y1
Verberne, HJ1
Nogales, P1
Velasco, C1
Mota-Cobián, A1
González-Cintado, L1
Mota, RA1
España, S1
Mateo, J1
Bentzon, JF1
Forsythe, RO1
McBride, OMB1
Vesey, AT2
Semple, SI1
Shah, ASV1
Adamson, PD1
Wallace, WA1
Kaczynski, J1
Ho, W1
van Beek, EJR1
Gray, CD1
Fletcher, A1
Lucatelli, C1
Marin, A1
Burns, P1
Tambyraja, A1
Chalmers, RTA1
Weir, G1
Mitchard, N1
Tavares, A1
Robson, JMJ1
Majeed, K1
Kim, JM1
Lee, ES1
Park, KY1
Seok, JW1
Kwon, OS1
Raggi, P1
Prandini, N1
Ligabue, G1
Braglia, G1
Esposito, F1
Milic, J1
Malagoli, A1
Scaglioni, R1
Besutti, G1
Beghetto, B1
Nardini, G1
Roncaglia, E1
Mussini, C1
Guaraldi, G1
Morbelli, S1
Fiz, F1
Piccardo, A1
Picori, L1
Massollo, M1
Pestarino, E1
Marini, C1
Cabria, M1
Democrito, A1
Cittadini, G1
Villavecchia, G1
Bruzzi, P1
Alavi, A2
Sambuceti, G1
Joshi, NV1
Vesey, A1
Derlin, T1
Janssen, T1
Salamon, J1
Veldhoen, S1
Busch, JD1
Schön, G1
Herrmann, J1
Henes, FO1
Bannas, P1
Adam, G1
Buscombe, JR1
Quirce, R2
Martínez-Rodríguez, I2
Banzo, I2
Jiménez-Bonilla, J1
Martínez-Amador, N1
Ibáñez-Bravo, S1
López-Defilló, J1
Jiménez-Alonso, M1
Revilla, MA2
Carril, JM2
Irkle, A1
Lewis, DY1
Skepper, JN1
Bird, JL1
Joshi, FR2
Gallagher, FA1
Warburton, EA1
Bennett, MR1
Brindle, KM1
Rudd, JH2
Davenport, AP1
McKenney-Drake, ML1
Territo, PR1
Salavati, A1
Houshmand, S1
Persohn, S1
Liang, Y1
Alloosh, M1
Moe, SM1
Weaver, CM1
Sturek, M1
Oudkerk, SF1
de Jong, PA1
Blomberg, BA1
Scholtens, AM1
Mali, WP1
Spiering, W1
Doris, MK1
Cocker, MS1
Spence, JD1
Hammond, R1
Wells, G1
deKemp, RA1
Lum, C1
Adeeko, A1
Yaffe, MJ1
Leung, E1
Hill, A1
Nagpal, S1
Stotts, G1
Alturkustani, M1
Hammond, L1
DaSilva, J1
Hadizad, T1
Tardif, JC1
Beanlands, RS1
Pipitone, N1
Salvarani, C1
Versari, A1
Ferreira, MJV1
Oliveira-Santos, M1
Silva, R1
Gomes, A1
Ferreira, N1
Abrunhosa, A1
Lima, J1
Pego, M1
Gonçalves, L1
Castelo-Branco, M1
Robson, PM1
Trivieri, MG1
Abgral, R1
Karakatsanis, NA1
Contreras, J1
Gidwani, U1
Narula, JP1
Fuster, V1
Kovacic, JC1
Fayad, ZA1
Li, Y1
Berenji, GR1
Shaba, WF1
Tafti, B1
Yevdayev, E1
Dadparvar, S1
De Arcocha Torres, M1
Jiménez-Bonilla, JF1
Rebollo, M1
Palacio, E1
Rubio-Vassallo, A1
Ortega-Nava, F1
Del Castillo-Matos, R1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
SoFIA3: Sodium Fluoride Imaging (18F-NaF PET-CT) in Abdominal Aortic Aneurysms[NCT02229006]96 participants (Actual)Observational2014-09-30Completed
Low-dose Colchicine Inhibit Abdominal Aortic Aneurysm Growth Trial[NCT05361772]230 participants (Anticipated)Interventional2022-06-01Not yet recruiting
Rosuvastatin Effect on Atherosclerotic Plaque Metabolism - a Subclinical Atherosclerosis Imaging Study With 18F-NaF PET-CT[NCT03233243]Phase 440 participants (Actual)Interventional2020-07-27Completed
SALTIRE II: Bisphosphonates and RANKL Inhibition in Aortic Stenosis[NCT02132026]Phase 2152 participants (Actual)Interventional2014-11-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for sodium fluoride and Vascular Calcification

ArticleYear
Advances in positron emission tomography tracers related to vascular calcification.
    Annals of nuclear medicine, 2022, Volume: 36, Issue:9

    Topics: Fluorine Radioisotopes; Humans; Plaque, Atherosclerotic; Positron Emission Tomography Computed Tomog

2022
Vulnerable plaque imaging using
    The British journal of radiology, 2020, Sep-01, Volume: 93, Issue:1113

    Topics: Computed Tomography Angiography; Coronary Artery Disease; Fluorine Radioisotopes; Humans; Movement;

2020
    Arteriosclerosis, thrombosis, and vascular biology, 2020, Volume: 40, Issue:7

    Topics: Animals; Calcinosis; Female; Fluorine Radioisotopes; Heart Valve Diseases; Humans; Impotence, Vascul

2020
Will 18F-sodium fluoride PET-CT imaging be the magic bullet for identifying vulnerable coronary atherosclerotic plaques?
    Current cardiology reports, 2014, Volume: 16, Issue:9

    Topics: Coronary Artery Disease; Fluorine Radioisotopes; Humans; Multimodal Imaging; Myocardial Infarction;

2014
Exploring the nature of atheroma and cardiovascular inflammation in vivo using positron emission tomography (PET).
    The British journal of radiology, 2015, Volume: 88, Issue:1053

    Topics: Aortic Aneurysm; Atherosclerosis; Coronary Vessels; Fluorodeoxyglucose F18; Gallium Radioisotopes; H

2015
Identification of early vascular calcification with (18)F-sodium fluoride: potential clinical application.
    Expert review of cardiovascular therapy, 2016, Volume: 14, Issue:6

    Topics: Disease Progression; Early Diagnosis; Humans; Plaque, Atherosclerotic; Positron Emission Tomography

2016

Trials

2 trials available for sodium fluoride and Vascular Calcification

ArticleYear
The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus: a post hoc analysis of a double-blind, randomized, placebo-controlled trial.
    The American journal of clinical nutrition, 2022, 01-11, Volume: 115, Issue:1

    Topics: Aged; Aorta; Coronary Vessels; Diabetes Mellitus; Diabetic Angiopathies; Dietary Supplements; Double

2022
Do we need FDG-PET/CT to assess atherosclerosis?
    European journal of nuclear medicine and molecular imaging, 2017, Volume: 44, Issue:2

    Topics: Adult; Aged; Aorta, Thoracic; Aortitis; Atherosclerosis; Causality; Comorbidity; Denmark; Fluorodeox

2017

Other Studies

22 other studies available for sodium fluoride and Vascular Calcification

ArticleYear
Atorvastatin Promotes Macrocalcification, But Not Microcalcification in Atherosclerotic Rabbits: An 18F-NaF PET/CT Study.
    Journal of cardiovascular pharmacology, 2021, 10-01, Volume: 78, Issue:4

    Topics: Animals; Aorta, Abdominal; Atherosclerosis; Atorvastatin; Calcium; Disease Models, Animal; Fluorine

2021
Atherogenic Indices as a Predictor of Aortic Calcification in Prostate Cancer Patients Assessed Using
    International journal of molecular sciences, 2022, Oct-27, Volume: 23, Issue:21

    Topics: Humans; Male; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Radiopharmaceut

2022
Aortic valve and coronary 18F-sodium fluoride activity: a common cause?
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021, Volume: 28, Issue:4

    Topics: Aortic Valve Stenosis; Coronary Artery Disease; Fluorine Radioisotopes; Humans; Positron Emission To

2021
Evolution of arterial [
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2021, Volume: 28, Issue:5

    Topics: Aorta, Abdominal; Aortic Diseases; Fluorine Radioisotopes; Humans; Male; Positron Emission Tomograph

2021
Arterial
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022, Volume: 29, Issue:4

    Topics: Arteries; Fluorine Radioisotopes; Humans; Positron Emission Tomography Computed Tomography; Sodium F

2022
Analysis of
    Arteriosclerosis, thrombosis, and vascular biology, 2021, Volume: 41, Issue:10

    Topics: Animals; Animals, Genetically Modified; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Disease

2021
    Journal of the American College of Cardiology, 2018, 02-06, Volume: 71, Issue:5

    Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Aortic Rupture; Case-Control Studies; Cohort St

2018
    Journal of the American College of Cardiology, 2018, 02-06, Volume: 71, Issue:5

    Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Aortic Rupture; Case-Control Studies; Cohort St

2018
    Journal of the American College of Cardiology, 2018, 02-06, Volume: 71, Issue:5

    Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Aortic Rupture; Case-Control Studies; Cohort St

2018
    Journal of the American College of Cardiology, 2018, 02-06, Volume: 71, Issue:5

    Topics: Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Aortic Rupture; Case-Control Studies; Cohort St

2018
In search of the vulnerable patient or the vulnerable plaque:
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018, Volume: 25, Issue:5

    Topics: Cardiovascular Diseases; Coronary Artery Disease; Fluorine Radioisotopes; Humans; Plaque, Atheroscle

2018
Comparison of [
    JACC. Cardiovascular imaging, 2019, Volume: 12, Issue:2

    Topics: Aged; Aged, 80 and over; Carotid Stenosis; Female; Fluorodeoxyglucose F18; Humans; Male; Plaque, Ath

2019
Molecular Imaging of Vascular Calcification with
    International journal of molecular sciences, 2019, Mar-08, Volume: 20, Issue:5

    Topics: Aged; Coronary Artery Disease; Disease Progression; Female; Fluorine Radioisotopes; HIV; HIV Infecti

2019
Divergent determinants of 18F-NaF uptake and visible calcium deposition in large arteries: relationship with Framingham risk score.
    The international journal of cardiovascular imaging, 2014, Volume: 30, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Calcium; Coronary Artery Disease; Coronary Vessels; Female; Fluorine

2014
Age-related differences in the activity of arterial mineral deposition and regional bone metabolism: a 18F-sodium fluoride positron emission tomography study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2015, Volume: 26, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Bone and Bones; Cardiovascular Diseases; Feasibility Studies;

2015
New insight of functional molecular imaging into the atheroma biology: 18F-NaF and 18F-FDG in symptomatic and asymptomatic carotid plaques after recent CVA. Preliminary results.
    Clinical physiology and functional imaging, 2016, Volume: 36, Issue:6

    Topics: Aged; Aged, 80 and over; Asymptomatic Diseases; Carotid Arteries; Carotid Artery Diseases; Female; F

2016
Identifying active vascular microcalcification by (18)F-sodium fluoride positron emission tomography.
    Nature communications, 2015, Jul-07, Volume: 6

    Topics: Aged; Atherosclerosis; Carotid Arteries; Female; Fluorine Radioisotopes; Humans; Male; Positron-Emis

2015
(18)F-NaF PET Imaging of Early Coronary Artery Calcification.
    JACC. Cardiovascular imaging, 2016, Volume: 9, Issue:5

    Topics: Animals; Coronary Artery Disease; Coronary Vessels; Diet, Atherogenic; Disease Models, Animal; Disea

2016
Whole-Body Visualization of Ectopic Bone Formation of Arteries and Skin in Pseudoxanthoma Elasticum.
    JACC. Cardiovascular imaging, 2016, Volume: 9, Issue:6

    Topics: Adult; Aged; Calcinosis; Female; Femoral Artery; Humans; Middle Aged; Multidetector Computed Tomogra

2016
[
    JACC. Cardiovascular imaging, 2017, Volume: 10, Issue:4

    Topics: Aged; Carotid Arteries; Carotid Artery Diseases; Female; Fluorine Radioisotopes; Humans; Male; Middl

2017
Assessment of atherosclerotic plaque calcification using F18-NaF PET-CT.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2018, Volume: 25, Issue:5

    Topics: Aged; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Plaque, Atherosclerotic; Positron E

2018
Coronary Artery PET/MR Imaging: Feasibility, Limitations, and Solutions.
    JACC. Cardiovascular imaging, 2017, Volume: 10, Issue:10 Pt A

    Topics: Adult; Aged; Algorithms; Artifacts; Contrast Media; Coronary Artery Disease; Coronary Vessels; Feasi

2017
Association of vascular fluoride uptake with vascular calcification and coronary artery disease.
    Nuclear medicine communications, 2012, Volume: 33, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Atherosclerosis; Coronary Artery Disease; Feasibility Studies; Femal

2012
Contribution of 18F-sodium fluoride PET/CT to the study of the carotid atheroma calcification.
    Revista espanola de medicina nuclear e imagen molecular, 2013, Volume: 32, Issue:1

    Topics: Aged; Aged, 80 and over; Carotid Artery Diseases; Female; Fluorine Radioisotopes; Humans; Male; Midd

2013
Noninvasive imaging in cardiovascular therapy: the promise of coronary arterial ¹⁸F-sodium fluoride uptake as a marker of plaque biology.
    Expert review of cardiovascular therapy, 2012, Volume: 10, Issue:9

    Topics: Atherosclerosis; Biological Transport; Biomarkers; Coronary Artery Disease; Coronary Vessels; Diseas

2012