lactic acid has been researched along with Vascular Calcification in 8 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
| Excerpt | Relevance | Reference |
|---|
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 5 (62.50) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, Y | 5 |
| Zhang, JL | 1 |
| Yan, XJ | 1 |
| Ji, Y | 1 |
| Wang, FF | 1 |
| Chen, J | 1 |
| Yu, H | 1 |
| Tan, X | 1 |
| Mok, SWF | 1 |
| Xie, Y | 1 |
| Wang, Y | 2 |
| Jiang, X | 1 |
| Macrae, VE | 1 |
| Lan, L | 1 |
| Fu, X | 1 |
| Zhu, D | 1 |
| Han, XQ | 3 |
| Sun, XJ | 3 |
| Yang, R | 2 |
| Ma, WQ | 3 |
| Liu, NF | 4 |
| Ji, JJ | 2 |
| Wang, XD | 1 |
| Li, M | 1 |
| Wei, Q | 1 |
| Ren, LQ | 1 |
| Niu, J | 1 |
| Wu, C | 1 |
| Zhang, M | 1 |
| Yang, Z | 1 |
| Liu, Z | 1 |
| Fu, F | 1 |
| Li, J | 2 |
| Feng, N | 1 |
| Gu, X | 1 |
| Zhang, S | 1 |
| Liu, Y | 1 |
| Fan, R | 1 |
| Pei, J | 1 |
| Wang, X | 1 |
| Sinha, A | 1 |
| Shaporev, A | 1 |
| Nosoudi, N | 1 |
| Lei, Y | 1 |
| Vertegel, A | 1 |
| Lessner, S | 1 |
| Vyavahare, N | 1 |
8 other studies available for lactic acid and Vascular Calcification
| Article | Year |
|---|---|
Exploring a new mechanism between lactate and VSMC calcification: PARP1/POLG/UCP2 signaling pathway and imbalance of mitochondrial homeostasis.
Topics: DNA Polymerase gamma; DNA, Mitochondrial; Homeostasis; Humans; Lactic Acid; Mitochondria; Muscle, Sm | 2023 |
PFKFB3-driven vascular smooth muscle cell glycolysis promotes vascular calcification via the altered FoxO3 and lactate production.
Topics: Animals; Forkhead Box Protein O3; Glycolysis; Lactic Acid; Mice; MicroRNAs; Muscle, Smooth, Vascular | 2023 |
Lactate accelerates vascular calcification through NR4A1-regulated mitochondrial fission and BNIP3-related mitophagy.
Topics: Animals; Aorta; Bone Morphogenetic Protein 2; Cholecalciferol; Core Binding Factor Alpha 1 Subunit; | 2020 |
Periostin promotes arterial calcification through PPARγ-related glucose metabolism reprogramming.
Topics: Animals; Aorta, Thoracic; Apoptosis; Cell Adhesion Molecules; Computed Tomography Angiography; Coron | 2021 |
κ-opioid receptor stimulation alleviates rat vascular smooth muscle cell calcification via PFKFB3-lactate signaling.
Topics: Animals; Aorta; Cell Differentiation; Glycerophosphates; Glycolysis; Hypoxia-Inducible Factor-Prolin | 2021 |
Advanced glycation end products accelerate calcification in VSMCs through HIF-1α/PDK4 activation and suppress glucose metabolism.
Topics: Animals; Core Binding Factor Alpha 1 Subunit; Diabetes Mellitus; Gene Expression Regulation; Glucose | 2018 |
Lactate accelerates calcification in VSMCs through suppression of BNIP3-mediated mitophagy.
Topics: Animals; Cells, Cultured; Lactic Acid; Membrane Potential, Mitochondrial; Membrane Proteins; Mitocho | 2019 |
Nanoparticle targeting to diseased vasculature for imaging and therapy.
Topics: Animals; Aortic Aneurysm; Atherosclerosis; Diagnostic Imaging; Drug Delivery Systems; Lactic Acid; M | 2014 |