thioctic acid has been researched along with Vascular Calcification in 2 studies
Thioctic Acid: An octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme of oxoglutarate dehydrogenase (KETOGLUTARATE DEHYDROGENASE COMPLEX). It is used in DIETARY SUPPLEMENTS.
Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vascular calcification is prevalent in patients with chronic kidney disease and leads to increased cardiovascular morbidity and mortality." | 1.38 | α-Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway. ( Choi, YK; Ha, CM; Harris, RA; Jeong, D; Kim, H; Kim, HJ; Kim, HS; Kim, JM; Kim, JR; Kim, JY; Lee, IK; Lee, K; Lee, SJ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bassi, E | 1 |
| Liberman, M | 1 |
| Martinatti, MK | 1 |
| Bortolotto, LA | 1 |
| Laurindo, FR | 1 |
| Kim, H | 1 |
| Kim, HJ | 1 |
| Lee, K | 1 |
| Kim, JM | 1 |
| Kim, HS | 1 |
| Kim, JR | 1 |
| Ha, CM | 1 |
| Choi, YK | 1 |
| Lee, SJ | 1 |
| Kim, JY | 1 |
| Harris, RA | 1 |
| Jeong, D | 1 |
| Lee, IK | 1 |
2 other studies available for thioctic acid and Vascular Calcification
| Article | Year |
|---|---|
Lipoic acid, but not tempol, preserves vascular compliance and decreases medial calcification in a model of elastocalcinosis.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Compliance; Cyclic N-Oxides; Disease Models, Animal; Mal | 2014 |
α-Lipoic acid attenuates vascular calcification via reversal of mitochondrial function and restoration of Gas6/Axl/Akt survival pathway.
Topics: Animals; Apoptosis; Axl Receptor Tyrosine Kinase; Calcium; Caspase 3; Caspase 9; Cells, Cultured; Ch | 2012 |