beta-glycerophosphoric acid has been researched along with Vascular Calcification in 36 studies
beta-glycerophosphoric acid: plays role in mineralization of bone in vitro
glycerol 2-phosphate : A glycerol monophosphate having the phosphate group at the 2-position.
Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Melatonin has previously been shown to protect against cardiovascular disease, so this study sought to explore whether it attenuates vascular calcification by regulating mitochondrial fission via the AMP-activated protein kinase/dynamin-related protein 1 (AMPK/Drp1) signalling pathway." | 5.56 | Melatonin attenuates vascular calcification by inhibiting mitochondria fission via an AMPK/Drp1 signalling pathway. ( Chen, WR; Liu, F; Sha, Y; Wu, XP; Yang, JQ; Zhou, YJ, 2020) |
| "Ginsenoside Rb1 (Rb1) has been reported to protect the cardiovascular system against vascular diseases, yet its role in VC and the underlying mechanisms remain unclear." | 5.51 | Ginsenoside Rb1 ameliorates CKD-associated vascular calcification by inhibiting the Wnt/β-catenin pathway. ( Dai, H; Dong, M; Guo, M; Guo, R; Ji, X; Lin, Z; Lu, H; Wang, L; Zhang, X; Zhang, Z; Zhou, P, 2019) |
| "Pathologic vascular calcification is a significant reason for mortality and morbidity in patients who suffer from end-stage renal disease (ESRD)." | 5.43 | Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2. ( Du, Y; Li, G; Li, Y; Wang, L; Zhang, P; Zhou, F, 2016) |
| "Melatonin has previously been shown to protect against cardiovascular disease, so this study sought to explore whether it attenuates vascular calcification by regulating mitochondrial fission via the AMP-activated protein kinase/dynamin-related protein 1 (AMPK/Drp1) signalling pathway." | 1.56 | Melatonin attenuates vascular calcification by inhibiting mitochondria fission via an AMPK/Drp1 signalling pathway. ( Chen, WR; Liu, F; Sha, Y; Wu, XP; Yang, JQ; Zhou, YJ, 2020) |
| "Ginsenoside Rb1 (Rb1) has been reported to protect the cardiovascular system against vascular diseases, yet its role in VC and the underlying mechanisms remain unclear." | 1.51 | Ginsenoside Rb1 ameliorates CKD-associated vascular calcification by inhibiting the Wnt/β-catenin pathway. ( Dai, H; Dong, M; Guo, M; Guo, R; Ji, X; Lin, Z; Lu, H; Wang, L; Zhang, X; Zhang, Z; Zhou, P, 2019) |
| "Vascular calcification is a common problem in the elderly with diabetes, heart failure and end-stage renal disease." | 1.51 | Adiponectin inhibits vascular smooth muscle cell calcification induced by beta-glycerophosphate through JAK2/STAT3 signaling pathway. ( Guo, B; Jia, Y; Lu, Y; Ma, Y; Sun, J; Wang, R; Wei, R, 2019) |
| "Vascular calcification is one of the most important factors for high morbidity and mortality from cardiovascular and cerebrovascular diseases." | 1.46 | MiR-26a regulates vascular smooth muscle cell calcification in vitro through targeting CTGF. ( Dai, SL; Shang, YQ; Wang, XC; Wu, W; Yi, F, 2017) |
| "Vascular calcification is a frequent complication of atherosclerosis, diabetes and chronic kidney disease." | 1.43 | Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells. ( Agarwal, A; Arosio, P; Balla, G; Balla, J; Balogh, E; Bányai, E; Becs, Á; Becs, G; Eaton, JW; Jeney, V; Kovács, KÉ; Nyitrai, M; Poli, M; Zarjou, A, 2016) |
| "Aldosterone and SATB2 were found to be markedly upregulated during VSMC calcification, whereas miR-34b/c expression was downregulated." | 1.43 | MicroRNA-34b/c inhibits aldosterone-induced vascular smooth muscle cell calcification via a SATB2/Runx2 pathway. ( Cong, G; Hao, J; Hao, L; Ren, L; Zhang, L, 2016) |
| "Pathologic vascular calcification is a significant reason for mortality and morbidity in patients who suffer from end-stage renal disease (ESRD)." | 1.43 | Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2. ( Du, Y; Li, G; Li, Y; Wang, L; Zhang, P; Zhou, F, 2016) |
| "Vascular calcification is highly prevalent in patients with chronic kidney disease (CKD) and contributes to increased risk of cardiovascular disease and mortality." | 1.40 | miR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment. ( Cao, H; Dai, C; Fang, L; He, W; Jiang, L; Su, W; Wen, P; Xu, H; Yang, J; Ye, H; Zhou, Y, 2014) |
| "Vascular calcification was confirmed in 78." | 1.38 | Involvement of parathyroid hormone-related protein in vascular calcification of chronic haemodialysis patients. ( Fan, W; Fu, P; Gou, R; Huang, S; Huang, Y; Liu, F; Qiu, H; Zhong, H, 2012) |
| "Vascular calcification is a hallmark of cardiovascular disease." | 1.38 | Interleukin-24 attenuates β-glycerophosphate-induced calcification of vascular smooth muscle cells by inhibiting apoptosis, the expression of calcification and osteoblastic markers, and the Wnt/β-catenin pathway. ( Choi, HR; Kang, HA; Kang, HS; Lee, HY; Lee, KM; Oh, JW; Park, M; Yun, CH, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.78) | 29.6817 |
| 2010's | 28 (77.78) | 24.3611 |
| 2020's | 7 (19.44) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, F | 1 |
| Li, J | 3 |
| Gu, C | 1 |
| Zhang, H | 1 |
| Zhou, P | 1 |
| Zhang, X | 3 |
| Guo, M | 1 |
| Guo, R | 1 |
| Wang, L | 4 |
| Zhang, Z | 2 |
| Lin, Z | 1 |
| Dong, M | 1 |
| Dai, H | 1 |
| Ji, X | 1 |
| Lu, H | 1 |
| Lu, Y | 1 |
| Ma, Y | 1 |
| Wang, R | 1 |
| Sun, J | 1 |
| Guo, B | 1 |
| Wei, R | 1 |
| Jia, Y | 1 |
| Chen, J | 1 |
| Meng, Q | 1 |
| Li, D | 1 |
| Hu, FZ | 1 |
| Zhu, YQ | 1 |
| Huang, YY | 1 |
| Liu, YN | 1 |
| Sun, L | 1 |
| Liang, QH | 2 |
| Chen, WR | 1 |
| Zhou, YJ | 1 |
| Sha, Y | 1 |
| Wu, XP | 1 |
| Yang, JQ | 1 |
| Liu, F | 2 |
| Alesutan, I | 1 |
| Moritz, F | 1 |
| Haider, T | 1 |
| Shouxuan, S | 1 |
| Gollmann-Tepeköylü, C | 1 |
| Holfeld, J | 1 |
| Pieske, B | 1 |
| Lang, F | 1 |
| Eckardt, KU | 1 |
| Heinzmann, SS | 1 |
| Voelkl, J | 1 |
| Buchet, R | 1 |
| Tribes, C | 1 |
| Rouaix, V | 1 |
| Doumèche, B | 1 |
| Fiore, M | 1 |
| Wu, Y | 2 |
| Magne, D | 1 |
| Mebarek, S | 1 |
| Niu, J | 1 |
| Wu, C | 1 |
| Zhang, M | 1 |
| Yang, Z | 1 |
| Liu, Z | 1 |
| Fu, F | 1 |
| Feng, N | 1 |
| Gu, X | 1 |
| Zhang, S | 1 |
| Liu, Y | 4 |
| Fan, R | 1 |
| Pei, J | 1 |
| Ning, FL | 1 |
| Tao, J | 1 |
| Li, DD | 1 |
| Tian, LL | 1 |
| Wang, ML | 1 |
| Reilly, S | 1 |
| Liu, C | 1 |
| Cai, H | 1 |
| Xin, H | 1 |
| Zhang, XM | 1 |
| Wu, W | 1 |
| Shang, YQ | 1 |
| Dai, SL | 1 |
| Yi, F | 1 |
| Wang, XC | 1 |
| Jiang, W | 1 |
| Yang, H | 1 |
| Lin, Q | 1 |
| Qin, X | 1 |
| Hao, W | 1 |
| Yang, R | 1 |
| Yang, Y | 1 |
| Jin, S | 1 |
| Li, Y | 4 |
| Yuan, F | 1 |
| Guo, Q | 1 |
| Xiao, L | 1 |
| Wang, X | 1 |
| Wang, F | 1 |
| Teng, X | 1 |
| Ter Braake, AD | 1 |
| Tinnemans, PT | 1 |
| Shanahan, CM | 1 |
| Hoenderop, JGJ | 1 |
| de Baaij, JHF | 1 |
| Lin, F | 1 |
| Fu, Y | 1 |
| Chen, W | 2 |
| Liu, W | 1 |
| Chi, J | 1 |
| Yin, X | 1 |
| Tian, BY | 2 |
| Yao, L | 2 |
| Sheng, ZT | 2 |
| Wan, PZ | 1 |
| Qiu, XB | 2 |
| Wang, J | 2 |
| Xu, TH | 2 |
| Han, YR | 1 |
| Wang, C | 1 |
| Tang, Y | 1 |
| Wang, Y | 1 |
| Li, G | 2 |
| Chen, YX | 1 |
| Huang, C | 1 |
| Duan, ZB | 1 |
| Xu, CY | 1 |
| Chen, Y | 1 |
| Mahmoud, AM | 1 |
| Jones, AM | 1 |
| Sidgwick, GP | 1 |
| Arafat, AM | 1 |
| Alexander, YM | 1 |
| Wilkinson, FL | 1 |
| Liao, XB | 2 |
| Zhang, ZY | 1 |
| Yuan, K | 1 |
| Feng, X | 1 |
| Cui, RR | 2 |
| Hu, YR | 1 |
| Yuan, ZS | 1 |
| Gu, L | 1 |
| Li, SJ | 2 |
| Mao, DA | 2 |
| Lu, Q | 1 |
| Zhou, XM | 1 |
| de Jesus Perez, VA | 1 |
| Yuan, LQ | 2 |
| Cao, X | 1 |
| Li, H | 1 |
| Tao, H | 1 |
| Wu, N | 1 |
| Yu, L | 1 |
| Zhang, D | 1 |
| Lu, X | 1 |
| Zhu, J | 1 |
| Lu, Z | 1 |
| Zhu, Q | 1 |
| Wen, P | 1 |
| Cao, H | 1 |
| Fang, L | 1 |
| Ye, H | 1 |
| Zhou, Y | 1 |
| Jiang, L | 1 |
| Su, W | 1 |
| Xu, H | 1 |
| He, W | 1 |
| Dai, C | 1 |
| Yang, J | 1 |
| Becs, G | 1 |
| Zarjou, A | 1 |
| Agarwal, A | 1 |
| Kovács, KÉ | 1 |
| Becs, Á | 1 |
| Nyitrai, M | 1 |
| Balogh, E | 1 |
| Bányai, E | 1 |
| Eaton, JW | 1 |
| Arosio, P | 1 |
| Poli, M | 1 |
| Jeney, V | 1 |
| Balla, J | 1 |
| Balla, G | 1 |
| Fu, K | 1 |
| Xin, Y | 1 |
| Shi, Y | 1 |
| Zheng, X | 1 |
| Lyu, Y | 1 |
| Xu, Z | 1 |
| Liu, J | 1 |
| Li, EG | 1 |
| Tian, J | 1 |
| Xu, ZH | 1 |
| Zhang, W | 1 |
| Ding, H | 1 |
| Du, Y | 2 |
| Zhang, SL | 1 |
| Xu, JS | 1 |
| Yang, S | 1 |
| Bai, YL | 1 |
| Zhang, JX | 1 |
| Cui, LW | 1 |
| Yu, QY | 1 |
| Hao, J | 1 |
| Zhang, L | 1 |
| Cong, G | 1 |
| Ren, L | 1 |
| Hao, L | 1 |
| Xu, M | 1 |
| Liu, L | 1 |
| Song, C | 1 |
| Gui, S | 1 |
| Zhang, P | 1 |
| Zhou, F | 1 |
| Cui, XX | 1 |
| Wang, SW | 1 |
| Qi, P | 1 |
| Zhao, WH | 1 |
| Gou, BD | 1 |
| Zhang, TL | 1 |
| Wang, K | 1 |
| Fu, P | 1 |
| Fan, W | 1 |
| Gou, R | 1 |
| Huang, Y | 1 |
| Qiu, H | 1 |
| Zhong, H | 1 |
| Huang, S | 1 |
| Liu, LJ | 1 |
| Yi, L | 1 |
| Zhu, X | 1 |
| Liu, GY | 1 |
| Wu, SS | 1 |
| Liao, EY | 1 |
| Lee, KM | 1 |
| Kang, HA | 1 |
| Park, M | 1 |
| Lee, HY | 1 |
| Choi, HR | 1 |
| Yun, CH | 1 |
| Oh, JW | 1 |
| Kang, HS | 1 |
| Sasaki, T | 1 |
| Nakamura, K | 1 |
| Sasada, K | 1 |
| Okada, S | 1 |
| Cheng, XW | 1 |
| Suzuki, T | 1 |
| Murohara, T | 1 |
| Sato, K | 1 |
| Kuzuya, M | 1 |
36 other studies available for beta-glycerophosphoric acid and Vascular Calcification
| Article | Year |
|---|---|
MiR-140-5p upregulation suppressed β-glycerophosphate-induced vascular smooth muscle cell calcification via targeting TLR4.
Topics: Calcium; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Glycerophosphates; Humans; MicroRNAs; | 2022 |
Ginsenoside Rb1 ameliorates CKD-associated vascular calcification by inhibiting the Wnt/β-catenin pathway.
Topics: Animals; Calcium; Down-Regulation; Ginsenosides; Glycerophosphates; Male; Phenotype; PPAR gamma; Rat | 2019 |
Adiponectin inhibits vascular smooth muscle cell calcification induced by beta-glycerophosphate through JAK2/STAT3 signaling pathway.
Topics: Adiponectin; Animals; Cell Differentiation; Gene Expression Regulation; Glycerophosphates; Humans; J | 2019 |
The protective effects of long non-coding RNA-ANCR on arterial calcification.
Topics: Animals; Apoptosis; Autophagy-Related Protein 5; Bone Morphogenetic Protein 2; Calcitriol; Calcium; | 2020 |
Melatonin attenuates vascular calcification by inhibiting mitochondria fission via an AMPK/Drp1 signalling pathway.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Calcium; Cytoprotection; Dynamins; Glycerophospha | 2020 |
Impact of β-glycerophosphate on the bioenergetic profile of vascular smooth muscle cells.
Topics: Aorta; Cell Transdifferentiation; Cells, Cultured; Chondrogenesis; Energy Metabolism; Glycerophospha | 2020 |
Hydrolysis of Extracellular ATP by Vascular Smooth Muscle Cells Transdifferentiated into Chondrocytes Generates P
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Aorta; Ascorbic Acid; Atherosclerosis; Cell T | 2021 |
κ-opioid receptor stimulation alleviates rat vascular smooth muscle cell calcification via PFKFB3-lactate signaling.
Topics: Animals; Aorta; Cell Differentiation; Glycerophosphates; Glycolysis; Hypoxia-Inducible Factor-Prolin | 2021 |
Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling.
Topics: Alkaline Phosphatase; Animals; Aorta, Thoracic; Benzimidazoles; Cholecalciferol; Disease Models, Ani | 2022 |
MiR-26a regulates vascular smooth muscle cell calcification in vitro through targeting CTGF.
Topics: Alkaline Phosphatase; Cells, Cultured; Connective Tissue Growth Factor; Glycerophosphates; Humans; M | 2017 |
The miR-182/SORT1 axis regulates vascular smooth muscle cell calcification in vitro and in vivo.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Atherosclerosis; Calcinosis; Cell Line; Cholecalcife | 2018 |
Stellate ganglion block ameliorates vascular calcification by inhibiting endoplasmic reticulum stress.
Topics: Animals; Aorta; Autonomic Nerve Block; Calcium; Cholecalciferol; Disease Models, Animal; Endoplasmic | 2018 |
Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation.
Topics: Alkaline Phosphatase; Animals; Apoptosis; Boron Compounds; Cattle; Cells, Cultured; Durapatite; Glyc | 2018 |
Cortistatin inhibits arterial calcification in rats via GSK3β/β-catenin and protein kinase C signalling but not c-Jun N-terminal kinase signalling.
Topics: Animals; beta Catenin; Cholecalciferol; Disease Models, Animal; Glycerophosphates; Glycogen Synthase | 2018 |
Specific knockdown of WNT8b expression protects against phosphate-induced calcification in vascular smooth muscle cells by inhibiting the Wnt-β-catenin signaling pathway.
Topics: Actins; Alkaline Phosphatase; Calcium; Cells, Cultured; Gene Knockdown Techniques; Glycerophosphates | 2019 |
Restoration of microRNA-30b expression alleviates vascular calcification through the mTOR signaling pathway and autophagy.
Topics: Animals; Aorta; Autophagy; Beclin-1; Core Binding Factor Alpha 1 Subunit; Epigenomics; Gene Expressi | 2019 |
Label-free quantitative proteomics identifies Smarca4 is involved in vascular calcification.
Topics: Animals; Aorta; Biomarkers; Cell Line; Disease Models, Animal; DNA Helicases; Glycerophosphates; Hum | 2019 |
Klotho/FGF23 axis mediates high phosphate-induced vascular calcification in vascular smooth muscle cells via Wnt7b/β-catenin pathway.
Topics: Alkaline Phosphatase; Animals; Aorta; beta Catenin; Calcium; Fibroblast Growth Factor-23; Fibroblast | 2019 |
Small Molecule Glycomimetics Inhibit Vascular Calcification via c-Met/Notch3/HES1 Signalling.
Topics: Biomimetic Materials; Bone Morphogenetic Protein 2; Cell Line; Core Binding Factor Alpha 1 Subunit; | 2019 |
MiR-133a modulates osteogenic differentiation of vascular smooth muscle cells.
Topics: 3' Untranslated Regions; Animals; Biomarkers; Cell Transdifferentiation; Cells, Cultured; Core Bindi | 2013 |
Metformin inhibits vascular calcification in female rat aortic smooth muscle cells via the AMPK-eNOS-NO pathway.
Topics: AMP-Activated Protein Kinases; Animals; Aorta; Cell Transdifferentiation; Cells, Cultured; Diabetic | 2013 |
miR-125b/Ets1 axis regulates transdifferentiation and calcification of vascular smooth muscle cells in a high-phosphate environment.
Topics: Alkaline Phosphatase; Animals; Aorta; Blotting, Western; Calcification, Physiologic; Cell Transdiffe | 2014 |
Pharmacological induction of ferritin prevents osteoblastic transformation of smooth muscle cells.
Topics: Alkaline Phosphatase; Aorta; Calcitriol; Calcium; Cells, Cultured; Cholecalciferol; Ergocalciferols; | 2016 |
[Effects and mechanism of fibroblast growth factor 21 on rat vascular smooth muscle cells calcification].
Topics: Animals; Calcium; Fibroblast Growth Factors; Glycerophosphates; Muscle, Smooth, Vascular; Myocytes, | 2015 |
Effects of Gingko biloba extract (EGb 761) on vascular smooth muscle cell calcification induced by β-glycerophosphate.
Topics: Animals; Cells, Cultured; Ginkgo biloba; Glycerophosphates; Male; Muscle, Smooth, Vascular; Phytothe | 2016 |
Hydrogen peroxide prevents vascular calcification induced ROS production by regulating Nrf-2 pathway.
Topics: Animals; Antioxidants; Aorta; Cells, Cultured; Glycerophosphates; Humans; Hydrogen Peroxide; Kidney | 2016 |
[Effects of intermediate conductance calcium-activated potassium channel blocker TARAM-34 on β-glycerophosphate induced vascular smooth muscle cells calcification].
Topics: Animals; Aorta, Thoracic; Calcinosis; Calcium; Cell Differentiation; Cells, Cultured; Core Binding F | 2016 |
MicroRNA-34b/c inhibits aldosterone-induced vascular smooth muscle cell calcification via a SATB2/Runx2 pathway.
Topics: 3' Untranslated Regions; Aldosterone; Animals; Aorta; Base Sequence; Core Binding Factor Alpha 1 Sub | 2016 |
Ghrelin improves vascular autophagy in rats with vascular calcification.
Topics: AMP-Activated Protein Kinases; Animals; Aorta; Autophagy; Calcium; Cholecalciferol; Disease Models, | 2017 |
Resveratrol Ameliorated Vascular Calcification by Regulating Sirt-1 and Nrf2.
Topics: Animals; Antioxidants; Cells, Cultured; Glycerophosphates; Heme Oxygenase-1; Male; Mitochondria, Mus | 2016 |
[Studies on the mechanism of arterial in vitro calcification].
Topics: Animals; Cell Differentiation; Cells, Cultured; Collagen Type X; Glycerophosphates; Hydroxycholester | 2001 |
Lanthanum chloride bidirectionally influences calcification in bovine vascular smooth muscle cells.
Topics: Alkaline Phosphatase; Animals; Apoptosis; Atherosclerosis; Calcium Phosphates; Caspases; Cattle; Cel | 2012 |
Involvement of parathyroid hormone-related protein in vascular calcification of chronic haemodialysis patients.
Topics: Adult; Alkaline Phosphatase; Aorta; Blotting, Western; Bone Morphogenetic Protein 2; Calcium; Case-C | 2012 |
MicroRNA-204 regulates vascular smooth muscle cell calcification in vitro and in vivo.
Topics: Animals; Biomarkers; Cell Differentiation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Fem | 2012 |
Interleukin-24 attenuates β-glycerophosphate-induced calcification of vascular smooth muscle cells by inhibiting apoptosis, the expression of calcification and osteoblastic markers, and the Wnt/β-catenin pathway.
Topics: Animals; Apoptosis; beta Catenin; Biomarkers; Cells, Cultured; Glycerophosphates; Humans; Interleuki | 2012 |
Matrix metalloproteinase-2 deficiency impairs aortic atherosclerotic calcification in ApoE-deficient mice.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Chondrocytes; Glycerophosphates | 2013 |