Page last updated: 2024-10-22

acetazolamide and Vascular Calcification

acetazolamide has been researched along with Vascular Calcification in 2 studies

Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.

Research Excerpts

ExcerptRelevanceReference
"Vascular calcification is a recognised source of morbidity among mid-age and elderly subjects."5.51Would acetazolamide inhibit progression of atheromatous vascular calcification? ( Cochran, M, 2019)
"Acetazolamide (ACM) treatment partially reversed the growth deficit of kl/kl mice."5.43Acetazolamide sensitive tissue calcification and aging of klotho-hypomorphic mice. ( Alesutan, I; Castor, T; Kohlhofer, U; Kübler, L; Kuro-o, M; Lang, F; Leibrock, CB; Mannheim, JG; Michael, D; Pichler, BJ; Quintanilla-Martinez, L; Rosenblatt, KP; Voelkl, J, 2016)
"Vascular calcification is a recognised source of morbidity among mid-age and elderly subjects."1.51Would acetazolamide inhibit progression of atheromatous vascular calcification? ( Cochran, M, 2019)
"Acetazolamide (ACM) treatment partially reversed the growth deficit of kl/kl mice."1.43Acetazolamide sensitive tissue calcification and aging of klotho-hypomorphic mice. ( Alesutan, I; Castor, T; Kohlhofer, U; Kübler, L; Kuro-o, M; Lang, F; Leibrock, CB; Mannheim, JG; Michael, D; Pichler, BJ; Quintanilla-Martinez, L; Rosenblatt, KP; Voelkl, J, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cochran, M1
Leibrock, CB1
Alesutan, I1
Voelkl, J1
Michael, D1
Castor, T1
Kohlhofer, U1
Quintanilla-Martinez, L1
Kübler, L1
Mannheim, JG1
Pichler, BJ1
Rosenblatt, KP1
Kuro-o, M1
Lang, F1

Other Studies

2 other studies available for acetazolamide and Vascular Calcification

ArticleYear
Would acetazolamide inhibit progression of atheromatous vascular calcification?
    Medical hypotheses, 2019, Volume: 132

    Topics: Acetazolamide; Acidosis; Aged; Alkaline Phosphatase; Calcium; Disease Progression; Humans; Hydrogen-

2019
Acetazolamide sensitive tissue calcification and aging of klotho-hypomorphic mice.
    Journal of molecular medicine (Berlin, Germany), 2016, Volume: 94, Issue:1

    Topics: Acetazolamide; Acidosis; Aging; Alkaline Phosphatase; Animals; Calcitriol; Calcium; Carbonic Anhydra

2016