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3-hydroxybutyric acid and Vascular Calcification

3-hydroxybutyric acid has been researched along with Vascular Calcification in 2 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.

Research Excerpts

ExcerptRelevanceReference
"Vascular calcification is an actively regulated process resembling bone formation and contributes to the cardiovascular morbidity and mortality of chronic kidney disease (CKD)."1.72Downregulation of HDAC9 by the ketone metabolite β-hydroxybutyrate suppresses vascular calcification. ( Chen, A; Dong, Q; Fu, M; Lan, Z; Li, L; Li, Y; Liang, Q; Liu, X; Lu, L; Ou, JS; Qiu, X; Wang, S; Yan, J; Ye, Y; Zhu, Z, 2022)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Lan, Z1
Chen, A1
Li, L1
Ye, Y1
Liang, Q1
Dong, Q1
Wang, S1
Fu, M1
Li, Y1
Liu, X1
Zhu, Z1
Ou, JS1
Qiu, X1
Lu, L1
Yan, J1
Vojinovic, D1
van der Lee, SJ1
van Duijn, CM1
Vernooij, MW1
Kavousi, M1
Amin, N1
Demirkan, A1
Ikram, MA1
van der Lugt, A1
Bos, D1

Other Studies

2 other studies available for 3-hydroxybutyric acid and Vascular Calcification

ArticleYear
Downregulation of HDAC9 by the ketone metabolite β-hydroxybutyrate suppresses vascular calcification.
    The Journal of pathology, 2022, Volume: 258, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Calcium; Cells, Cultured; Down-Regulation; Histone Deacetylases; Hum

2022
Metabolic profiling of intra- and extracranial carotid artery atherosclerosis.
    Atherosclerosis, 2018, Volume: 272

    Topics: 3-Hydroxybutyric Acid; Aged; Atherosclerosis; Calcinosis; Carotid Artery Diseases; Carotid Artery, I

2018