Compounds > indican
Page last updated: 2024-08-21

indican and Vascular Calcification

indican has been researched along with Vascular Calcification in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (78.57)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Chen, L; Gao, F; He, X; Jiang, H; Liang, S; Wei, M1
Cai, J; Chen, J; Ding, X; Gu, Y; Ning, Y; Shi, Y; Song, N; Zhang, H; Zhang, X1
Kuo, WH; Lee, CT; Lee, YT; Leung, FF; Ng, HY; Tain, YL1
Chen, L; Cheng, X; Gao, F; He, X; Jiang, H; Wang, Z; Wei, L1
Chao, CT; Lin, SH1
Chen, J; Ding, X; Gu, Y; Hu, J; Shen, Z; Xu, L; Zhang, H; Zhang, X1
Aoki, J; Asami, M; Horiuchi, Y; Ito, S; Tanabe, K; Tanimoto, S; Yoshida, E; Yoshida, M1
Chillon, JM; Hénaut, L; Kamel, S; Massy, ZA1
Bennis, Y; Bouabdallah, J; Caus, T; Choukroun, G; Issa, H; Kamel, S; Kchour, G; Lenglet, G; Six, I; Zibara, K1
Aikawa, E; Aikawa, M; Anderson, DG; Aster, JC; Barabási, AL; Boff, MS; Chen, M; Decano, JL; Golden, WS; Guimaraes, GC; Halu, A; Higashi, H; Iwata, H; Katsuki, S; Kauffman, KJ; Kum, AST; Kuromoto, RK; Lee, LH; Maejima, T; Nakano, T; Pestana, DVS; Sharma, A; Singh, SA; Suzuki, T1
Azmi, A; D'Haese, PC; De Leger, W; De Maré, A; Evenepoel, P; Maudsley, S; Meijers, B; Neven, E; Opdebeeck, B; Verhulst, A1
Cha, MU; Han, SH; Jhee, JH; Jung, SY; Kang, HY; Kang, SW; Kee, YK; Kim, H; Kim, HC; Kim, S; Kwon, YE; Lee, M; Lim, SK; Nam, BY; Park, J; Park, JT; Park, S; Seo, C; Um, JE; Wu, M; Yoo, TH; Yoon, CY; Yun, HR1
Chen, J; Ding, X; Ji, J; Liu, T; Teng, J; Zhang, H; Zhang, X1
Fujii, H; Goto, S; Kitamura, K; Kono, K; Nakai, K; Nishi, S1

Reviews

2 review(s) available for indican and Vascular Calcification

ArticleYear
Uremic Vascular Calcification: The Pathogenic Roles and Gastrointestinal Decontamination of Uremic Toxins.
    Toxins, 2020, Dec-21, Volume: 12, Issue:12

    Topics: Clinical Trials as Topic; Decontamination; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Indican; Isoquinolines; Renal Insufficiency, Chronic; Sulfonamides; Toxins, Biological; Uremia; Vascular Calcification

2020
Updates on the Mechanisms and the Care of Cardiovascular Calcification in Chronic Kidney Disease.
    Seminars in nephrology, 2018, Volume: 38, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Calcimimetic Agents; Calcium; Cardiovascular Diseases; Chelating Agents; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glucuronidase; Glycation End Products, Advanced; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indican; Inflammation; Klotho Proteins; Magnesium; Mesenchymal Stem Cells; Phosphates; Renal Insufficiency, Chronic; Tunica Intima; Tunica Media; Vascular Calcification; Vitamin K 2; Zinc Finger Protein GLI1

2018

Trials

1 trial(s) available for indican and Vascular Calcification

ArticleYear
Impact of Indoxyl Sulfate on Coronary Plaques in Patients on Hemodialysis.
    International heart journal, 2018, May-30, Volume: 59, Issue:3

    Topics: Aged; Biomarkers; Computed Tomography Angiography; Coronary Artery Disease; Coronary Vessels; Female; Humans; Indican; Male; Middle Aged; Multidetector Computed Tomography; Plaque, Atherosclerotic; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic; Risk Assessment; Vascular Calcification

2018

Other Studies

11 other study(ies) available for indican and Vascular Calcification

ArticleYear
Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway.
    Microscopy research and technique, 2019, Volume: 82, Issue:12

    Topics: Actins; Cell Line; Chromones; Core Binding Factor Alpha 1 Subunit; Down-Regulation; Humans; Indican; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Renal Insufficiency, Chronic; Signal Transduction; Sulfones; Up-Regulation; Vascular Calcification

2019
METTL14-dependent m6A regulates vascular calcification induced by indoxyl sulfate.
    Life sciences, 2019, Dec-15, Volume: 239

    Topics: Animals; Cells, Cultured; Female; Glucuronidase; Humans; Indican; Klotho Proteins; Male; Membrane Glycoproteins; Methylation; Methyltransferases; Muscle, Smooth, Vascular; Nerve Tissue Proteins; Osteogenesis; Rats; Rats, Sprague-Dawley; Vascular Calcification

2019
The role of TRPM7 in vascular calcification: Comparison between phosphate and uremic toxin.
    Life sciences, 2020, Nov-01, Volume: 260

    Topics: Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 7; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Humans; Indican; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphates; Protein Serine-Threonine Kinases; Receptors, Calcitriol; Renal Insufficiency, Chronic; TRPM Cation Channels; Vascular Calcification

2020
Indoxyl sulfate promotes osteogenic differentiation of vascular smooth muscle cells by miR-155-5p-dependent downregulation of matrix Gla protein via ROS/NF-κB signaling.
    Experimental cell research, 2020, 12-01, Volume: 397, Issue:1

    Topics: Animals; Calcium-Binding Proteins; Cell Differentiation; Extracellular Matrix Proteins; Gene Expression Regulation; Humans; Indican; Matrix Gla Protein; MicroRNAs; Muscle, Smooth, Vascular; NF-kappa B; Osteogenesis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renal Insufficiency, Chronic; Vascular Calcification

2020
Indoxyl sulfate accelerates vascular smooth muscle cell calcification via microRNA-29b dependent regulation of Wnt/β-catenin signaling.
    Toxicology letters, 2018, Mar-01, Volume: 284

    Topics: beta Catenin; Cell Culture Techniques; Cells, Cultured; Down-Regulation; Humans; Indican; Kidney Failure, Chronic; MicroRNAs; Muscle, Smooth, Vascular; Radial Artery; Signal Transduction; Vascular Calcification; Wnt Proteins

2018
Endothelial cells exposed to phosphate and indoxyl sulphate promote vascular calcification through interleukin-8 secretion.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2019, 07-01, Volume: 34, Issue:7

    Topics: Animals; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Human Umbilical Vein Endothelial Cells; Humans; Indican; Interleukin-8; Male; Myocytes, Smooth Muscle; Phosphates; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Vascular Calcification

2019
Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.
    Circulation, 2019, 01-02, Volume: 139, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Animals; Atherosclerosis; Calcium-Binding Proteins; Disease Models, Animal; Humans; Indican; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Intracellular Signaling Peptides and Proteins; Macrophage Activation; Macrophages; Male; Membrane Proteins; Mice; Mice, Knockout; Organic Anion Transporters; Phenotype; Plaque, Atherosclerotic; RAW 264.7 Cells; Receptors, LDL; Receptors, Notch; Renal Insufficiency, Chronic; Signal Transduction; Vascular Calcification

2019
Indoxyl Sulfate and p-Cresyl Sulfate Promote Vascular Calcification and Associate with Glucose Intolerance.
    Journal of the American Society of Nephrology : JASN, 2019, Volume: 30, Issue:5

    Topics: Animals; Biological Products; Biopsy, Needle; Carbamates; Disease Models, Animal; Glucose Intolerance; Immunohistochemistry; Indican; Male; Metformin; Polyesters; Random Allocation; Rats; Rats, Wistar; Renal Insufficiency, Chronic; Sensitivity and Specificity; Vascular Calcification

2019
Low Dentin Matrix Protein 1 Is Associated With Incident Cardiovascular Events in Peritoneal Dialysis Patients.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2016, Volume: 31, Issue:12

    Topics: Animals; Cardiovascular Diseases; Case-Control Studies; Cell Line; Extracellular Matrix Proteins; Female; Humans; Incidence; Indican; Kaplan-Meier Estimate; Logistic Models; Male; Mice; Middle Aged; Osteocytes; Peritoneal Dialysis; Phosphoproteins; Proportional Hazards Models; Risk Factors; RNA, Messenger; Vascular Calcification

2016
Indoxyl Sulfate Enhance the Hypermethylation of Klotho and Promote the Process of Vascular Calcification in Chronic Kidney Disease.
    International journal of biological sciences, 2016, Volume: 12, Issue:10

    Topics: Animals; Cell Line; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Glucuronidase; Humans; Indican; Kidney Failure, Chronic; Klotho Proteins; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Tandem Mass Spectrometry; Vascular Calcification

2016
Association between AST-120 and abdominal aortic calcification in predialysis patients with chronic kidney disease.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:3

    Topics: Aged; Aorta, Abdominal; Aortic Diseases; Carbon; Cross-Sectional Studies; Female; Humans; Indican; Male; Middle Aged; Oxides; Renal Insufficiency, Chronic; Retrospective Studies; Tomography, X-Ray Computed; Vascular Calcification

2013