Page last updated: 2024-10-23

aspirin and Vascular Calcification

aspirin has been researched along with Vascular Calcification in 14 studies

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)
acetylsalicylate : A benzoate that is the conjugate base of acetylsalicylic acid, arising from deprotonation of the carboxy group.
acetylsalicylic acid : A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.

Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.

Research Excerpts

ExcerptRelevanceReference
" Among current therapies, low-dose aspirin has been shown to reduce cardiovascular thrombosis."7.96A Pathophysiologic Primary Prevention Review of Aspirin Administration to Prevent Cardiovascular Thrombosis. ( Burchiel, S; Eaton, RP; Schade, DS, 2020)
"8 years with 10-75% coronary artery stenosis, as assessed by coronary computed tomography angiography, were randomly assigned to sarpogrelate 300 mg/day plus aspirin 100 mg/day (SPG + ASA group) or aspirin 100 mg/day alone (ASA group) for 6 months."5.24Effect of sarpogrelate, a selective 5-HT ( Chun, EJ; Han, SJ; Hur, JH; Jang, HC; Kang, DK; Kim, HJ; Kim, KM; Lee, DH; Lee, JE; Lim, S; Min, SH; Oh, TJ, 2017)
"To examine the association between CAC, bleeding, and ASCVD and explore the net estimated effect of aspirin at different CAC thresholds."4.02Value of Coronary Artery Calcium Scanning in Association With the Net Benefit of Aspirin in Primary Prevention of Atherosclerotic Cardiovascular Disease. ( Ajufo, E; Ayers, CR; de Lemos, JA; Joshi, PH; Khera, A; Rohatgi, A; Vigen, R, 2021)
"Recent American College of Cardiology/American Heart Association Primary Prevention Guidelines recommended considering low-dose aspirin therapy only among adults 40 to 70 years of age who are at higher atherosclerotic cardiovascular disease (ASCVD) risk but not at high risk of bleeding."3.96Coronary Artery Calcium for Personalized Allocation of Aspirin in Primary Prevention of Cardiovascular Disease in 2019: The MESA Study (Multi-Ethnic Study of Atherosclerosis). ( Al Rifai, M; Blaha, MJ; Blumenthal, RS; Budoff, M; Cainzos-Achirica, M; Dardari, Z; Duprez, DA; Dzaye, O; Greenland, P; Hong, J; McEvoy, JW; Miedema, MD; Mortensen, MB; Nasir, K; Yeboah, J, 2020)
" Among current therapies, low-dose aspirin has been shown to reduce cardiovascular thrombosis."3.96A Pathophysiologic Primary Prevention Review of Aspirin Administration to Prevent Cardiovascular Thrombosis. ( Burchiel, S; Eaton, RP; Schade, DS, 2020)
"Aspirin has been the mainstay of both secondary and primary prevention of cardiovascular disease for half a century."2.72Aspirin in Primary Prevention: What Changed? A Critical Appraisal of Current Evidence. ( Dasa, O; Pearson, TA; Pepine, CJ, 2021)
"It is a marker of atherosclerotic plaque burden and the strongest independent predictor of future myocardial infarction and mortality."1.46Cardiac Society of Australia and New Zealand position statement executive summary: coronary artery calcium scoring. ( Chan, J; Chow, CK; Hamilton-Craig, CR; Jelinek, VM; Liew, GY; Younger, JF, 2017)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (35.71)24.3611
2020's9 (64.29)2.80

Authors

AuthorsStudies
Hu, S1
Belcaro, G1
Cesarone, MR1
Feragalli, B1
Cotellese, R1
Dugall, M1
Scipione, C1
Scipione, V1
Maione, C1
Paven, E1
Dillinger, JG1
Bal Dit Sollier, C1
Vidal-Trecan, T1
Berge, N1
Dautry, R1
Gautier, JF1
Drouet, L1
Riveline, JP1
Henry, P1
Lee, CH1
Kim, U1
Wokhlu, A1
Wymer, D1
Taasan, V1
Winchester, DE1
Cainzos-Achirica, M1
Miedema, MD1
McEvoy, JW1
Al Rifai, M1
Greenland, P1
Dardari, Z1
Budoff, M1
Blumenthal, RS1
Yeboah, J1
Duprez, DA1
Mortensen, MB1
Dzaye, O1
Hong, J1
Nasir, K1
Blaha, MJ1
Ajufo, E1
Ayers, CR1
Vigen, R1
Joshi, PH1
Rohatgi, A1
de Lemos, JA1
Khera, A1
Dasa, O1
Pepine, CJ1
Pearson, TA1
Schade, DS1
Burchiel, S1
Eaton, RP1
Kim, BS1
Chan, N1
Hsu, G1
Makaryus, AN1
Chopra, M1
Cohen, SL1
Makaryus, JN1
Hamilton-Craig, CR1
Chow, CK1
Younger, JF1
Jelinek, VM1
Chan, J1
Liew, GY1
Fiaccadori, E1
Maggiore, U1
Regolisti, G1
Ercan, S1
Davutoglu, V1
Ozer, O1
Soeiro, Ade M1
Mansur, Ade P1
Schaan, BD1
Caramelli, B1
Rochitte, CE1
Serrano, CV1
Garzillo, CL1
Calderaro, D1
Gualandro, DM1
Lima, EG1
Marcondes-Braga, FG1
Lima, FG1
Oliveira, FM1
Azevedo, FR1
Chauhan, H1
Salles, JE1
Soares, J1
Cardoso, JN1
Pellanda, LC1
Sacilotto, L1
Baracioli, L1
Bortolotto, LA1
César, LA1
Ochiai, ME1
Minami, MH1
Pinheiro, MB1
Moretti, MA1
Oliveira, MT1
Rezende, PC1
Lemos, PA1
Admoni, SN1
Lottenberg, SA1
Rocha, VZ1
Hueb, W1
Mathias, W1
Lee, DH1
Chun, EJ1
Hur, JH1
Min, SH1
Lee, JE1
Oh, TJ1
Kim, KM1
Jang, HC1
Han, SJ1
Kang, DK1
Kim, HJ1
Lim, S1

Reviews

1 review available for aspirin and Vascular Calcification

ArticleYear
Aspirin in Primary Prevention: What Changed? A Critical Appraisal of Current Evidence.
    The American journal of cardiology, 2021, 02-15, Volume: 141

    Topics: Aspirin; Cardiovascular Diseases; Coronary Artery Disease; Evidence-Based Medicine; Heart Disease Ri

2021

Trials

1 trial available for aspirin and Vascular Calcification

ArticleYear
Effect of sarpogrelate, a selective 5-HT
    Atherosclerosis, 2017, Volume: 257

    Topics: Adult; Aged; Ankle Brachial Index; Anti-Inflammatory Agents; Aspirin; Biomarkers; Computed Tomograph

2017

Other Studies

12 other studies available for aspirin and Vascular Calcification

ArticleYear
Central cardiovascular calcifications: supplementation with Pycnogenol® and Centellicum®: variations over 12 months.
    Minerva cardioangiologica, 2020, Volume: 68, Issue:1

    Topics: Aspirin; Cardiovascular Diseases; Centella; Coronary Artery Disease; Dietary Supplements; Disease Ma

2020
Determinants of aspirin resistance in patients with type 2 diabetes.
    Diabetes & metabolism, 2020, Volume: 46, Issue:5

    Topics: Aged; Arachidonic Acid; Aspirin; C-Reactive Protein; Coronary Artery Disease; Diabetes Mellitus, Typ

2020
Coronary artery aneurysm in Kawasaki disease: from multimodality imaging.
    Coronary artery disease, 2020, Volume: 31, Issue:2

    Topics: Anticoagulants; Aspirin; Computed Tomography Angiography; Coronary Aneurysm; Coronary Angiography; C

2020
Effect of Elevated Calcium Score on Normal Myocardial Perfusion Study on Clinician Management of Coronary Artery Disease Risk Factors.
    Critical pathways in cardiology, 2020, Volume: 19, Issue:2

    Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Cohort Studies; Coronary Artery Di

2020
Coronary Artery Calcium for Personalized Allocation of Aspirin in Primary Prevention of Cardiovascular Disease in 2019: The MESA Study (Multi-Ethnic Study of Atherosclerosis).
    Circulation, 2020, 05-12, Volume: 141, Issue:19

    Topics: Aged; Aged, 80 and over; Aspirin; Clinical Decision-Making; Computed Tomography Angiography; Coronar

2020
Value of Coronary Artery Calcium Scanning in Association With the Net Benefit of Aspirin in Primary Prevention of Atherosclerotic Cardiovascular Disease.
    JAMA cardiology, 2021, 02-01, Volume: 6, Issue:2

    Topics: Adult; Aspirin; Atherosclerosis; Cohort Studies; Coronary Artery Disease; Coronary Disease; Eye Hemo

2021
A Pathophysiologic Primary Prevention Review of Aspirin Administration to Prevent Cardiovascular Thrombosis.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2020, Volume: 26, Issue:7

    Topics: Aged; Aspirin; Cardiovascular Diseases; Coronary Artery Disease; Humans; Plaque, Atherosclerotic; Pr

2020
Sex Differences in Coronary Arterial Calcification in Symptomatic Patients.
    The American journal of cardiology, 2021, 06-15, Volume: 149

    Topics: Adult; Aspirin; Chest Pain; Cohort Studies; Computed Tomography Angiography; Coronary Angiography; C

2021
Cardiac Society of Australia and New Zealand position statement executive summary: coronary artery calcium scoring.
    The Medical journal of Australia, 2017, Oct-16, Volume: 207, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asymptomatic Diseases; Coronary Artery Disea

2017
Balancing thromboembolic risk against vitamin K antagonist-related bleeding and accelerated calcification: is fondaparinux the Holy Grail for end-stage renal disease patients with atrial fibrillation?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2013, Volume: 28, Issue:12

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Contraindications; Factor Xa Inhibitors; Fondaparinux;

2013
Breakage of floppy wire during coronary stenting and long-term outcome.
    Asian cardiovascular & thoracic annals, 2013, Volume: 21, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Aspirin; Cardiac Catheters; Coronary Angiography; Coronary Artery Di

2013
    Arquivos brasileiros de cardiologia, 2014, Volume: 102, Issue:5 Suppl 1

    Topics: Aspirin; Atherosclerosis; Brazil; Cardiovascular Diseases; Coronary Artery Disease; Diabetes Mellitu

2014