Page last updated: 2024-10-20

thiosulfates and Vascular Calcification

thiosulfates has been researched along with Vascular Calcification in 20 studies

Thiosulfates: Inorganic salts of thiosulfuric acid possessing the general formula R2S2O3.
thiosulfate(2-) : A divalent inorganic anion obtained by removal of both protons from thiosulfuric acid.

Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.

Research Excerpts

ExcerptRelevanceReference
" As the prevalence of cardiac complications is higher in CKD, we tested the effectiveness of STS in a rat model of adenine-induced vascular calcification and subjected the heart to IR."7.88Sodium thiosulfate mediated cardioprotection against myocardial ischemia-reperfusion injury is defunct in rat heart with co-morbidity of vascular calcification. ( Kurian, GA; Ramachandran, K; Ravindran, S, 2018)
" Sodium thiosulfate (STS) due to its multiple properties such as antioxidant and calcium chelation has been reported to prevent vascular calcification in uremic rats, without mentioning its impact on cerebral function."7.81Sodium thiosulfate protects brain in rat model of adenine induced vascular calcification. ( Kurian, GA; Sriram, R; Subhash, N, 2015)
"It is speculated that sodium thiosulfate can alleviate the progression of vascular calcification by changing the levels of calcification factors."5.69Effects of sodium thiosulfate on serum calcification factors in patients undergoing maintenance hemodialysis. ( Li, X; Liu, P; Long, X; Peng, H; Wang, Y; Xu, X, 2023)
"Renal failure was assessed by plasma and urinary markers."5.43The renal mitochondrial dysfunction in patients with vascular calcification is prevented by sodium thiosulfate. ( Krishnaraj, P; Kurian, GA; Ravindran, S, 2016)
" As the prevalence of cardiac complications is higher in CKD, we tested the effectiveness of STS in a rat model of adenine-induced vascular calcification and subjected the heart to IR."3.88Sodium thiosulfate mediated cardioprotection against myocardial ischemia-reperfusion injury is defunct in rat heart with co-morbidity of vascular calcification. ( Kurian, GA; Ramachandran, K; Ravindran, S, 2018)
" Sodium thiosulfate (STS) due to its multiple properties such as antioxidant and calcium chelation has been reported to prevent vascular calcification in uremic rats, without mentioning its impact on cerebral function."3.81Sodium thiosulfate protects brain in rat model of adenine induced vascular calcification. ( Kurian, GA; Sriram, R; Subhash, N, 2015)
"Calciphylaxis is a rare disorder of poor prognosis that can lead to intense, painful lesions involving the skin and subcutaneous tissue."2.61Calciphylaxis: Approach to Diagnosis and Management. ( Noureddine, L; Seethapathy, H, 2019)
"Calciphylaxis is a cutaneous ischemic infarct caused by total occlusion of blood vessels initiated by vascular calcification."2.61Calciphylaxis: Diagnosis, Pathogenesis, and Treatment. ( Chang, JJ, 2019)
"Renal failure was assessed by plasma and urinary markers."1.43The renal mitochondrial dysfunction in patients with vascular calcification is prevented by sodium thiosulfate. ( Krishnaraj, P; Kurian, GA; Ravindran, S, 2016)
"The key to successful treatment of calciphylaxis is fast diagnosing of the disease and appropriate treatment management."1.42[Calcific uremic arteriolopathy - treatment with sodium thiosulfate]. ( Blaštíková, J; Dvořáková, G; Souček, M; Svojanovský, J; Vyskočilová, M, 2015)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's15 (75.00)24.3611
2020's5 (25.00)2.80

Authors

AuthorsStudies
Liu, P1
Xu, X1
Wang, Y1
Long, X1
Li, X1
Peng, H1
Djuric, P1
Dimkovic, N1
Schlieper, G1
Djuric, Z1
Pantelic, M1
Mitrovic, M1
Jankovic, A1
Milanov, M1
Kuzmanovic Pficer, J1
Floege, J1
Seethapathy, H1
Noureddine, L1
Boyce, AM1
Gafni, RI1
Ferreira, CR1
Piccoli, GB1
Torreggiani, M1
Gendrot, L1
Nielsen, L1
Singh, A1
Tandon, S1
Tandon, C1
Olaoye, OA1
Koratala, A1
Ravindran, S2
Ramachandran, K1
Kurian, GA3
Saengpanit, D1
Chattranukulchai, P1
Tumkosit, M1
Siribumrungwong, M1
Katavetin, P1
Sitprija, V1
Praditpornsilpa, K1
Eiam-Ong, S1
Susantitaphong, P1
Chang, JJ1
Yonova, DH1
Vazelov, ES1
Trendafilov, II1
Stoinova, VV1
Nedevska, MT1
Antonov, SA1
Vyskočilová, M1
Svojanovský, J1
Blaštíková, J1
Dvořáková, G1
Souček, M1
Dusilová Sulková, S1
Disbrow, MB1
Qaqish, I1
Kransdorf, M1
Chakkera, HA1
Subhash, N1
Sriram, R1
Ossorio-García, L1
Jiménez-Gallo, D1
Arjona-Aguilera, C1
Linares-Barrios, M1
Krishnaraj, P1
O'Neill, WC1
Hardcastle, KI1
Li, JY1
Yong, TY1
Choudhry, M1
Rao, N1
Milton, C1
Juneja, R1
Barbara, JA1
Passaris, G1
Van Noten, C1
Janssen van Doorn, K1
Vermander, E1
Vlayen, S1
Verpooten, GA1
Couttenye, MM1

Reviews

4 reviews available for thiosulfates and Vascular Calcification

ArticleYear
Calciphylaxis: Approach to Diagnosis and Management.
    Advances in chronic kidney disease, 2019, Volume: 26, Issue:6

    Topics: Calciphylaxis; Chelating Agents; Humans; Kidney Failure, Chronic; Microvessels; Pain Management; Ren

2019
Generalized Arterial Calcification of Infancy: New Insights, Controversies, and Approach to Management.
    Current osteoporosis reports, 2020, Volume: 18, Issue:3

    Topics: Adenosine Monophosphate; Bone Density Conservation Agents; Calcinosis; Cardiovascular Agents; Chelat

2020
An update on vascular calcification and potential therapeutics.
    Molecular biology reports, 2021, Volume: 48, Issue:1

    Topics: Atherosclerosis; Calcimimetic Agents; Calcium; Denosumab; Diabetes Mellitus; Diphosphonates; Dyslipi

2021
Calciphylaxis: Diagnosis, Pathogenesis, and Treatment.
    Advances in skin & wound care, 2019, Volume: 32, Issue:5

    Topics: Calciphylaxis; Chelating Agents; Humans; Kidney Failure, Chronic; Kidney Transplantation; Pain Manag

2019

Trials

3 trials available for thiosulfates and Vascular Calcification

ArticleYear
Effects of sodium thiosulfate on serum calcification factors in patients undergoing maintenance hemodialysis.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2023, Volume: 27, Issue:6

    Topics: C-Reactive Protein; Humans; Renal Dialysis; Thiosulfates; Vascular Calcification

2023
Sodium thiosulphate and progression of vascular calcification in end-stage renal disease patients: a double-blind, randomized, placebo-controlled study.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2020, 01-01, Volume: 35, Issue:1

    Topics: Antioxidants; Aorta, Abdominal; Carotid Intima-Media Thickness; Disease Progression; Double-Blind Me

2020
Effect of Sodium Thiosulfate on Arterial Stiffness in End-Stage Renal Disease Patients Undergoing Chronic Hemodialysis (Sodium Thiosulfate-Hemodialysis Study): A Randomized Controlled Trial.
    Nephron, 2018, Volume: 139, Issue:3

    Topics: Adult; Aged; Ankle Brachial Index; C-Reactive Protein; Combined Modality Therapy; Coronary Artery Di

2018

Other Studies

13 other studies available for thiosulfates and Vascular Calcification

ArticleYear
Setting the clock back: new hope for dialysis patients. Sodium thiosulphate and the regression of vascular calcifications.
    Journal of nephrology, 2021, Volume: 34, Issue:1

    Topics: Double-Blind Method; Humans; Kidney Failure, Chronic; Renal Dialysis; Thiosulfates; Vascular Calcifi

2021
Patient with ESRD with vascular calcifications and ischaemic complications.
    BMJ case reports, 2017, Oct-04, Volume: 2017

    Topics: Fingers; Gangrene; Genitalia, Male; Hemodialysis, Home; Humans; Kidney Failure, Chronic; Male; Middl

2017
Sodium thiosulfate mediated cardioprotection against myocardial ischemia-reperfusion injury is defunct in rat heart with co-morbidity of vascular calcification.
    Biochimie, 2018, Volume: 147

    Topics: Adenine; Animals; Cardiotonic Agents; Heart; Male; Mitochondria; Myocardial Reperfusion Injury; Oxid

2018
First impressions of cardiovascular calcification treatment in hemodialysis patients with a new dialysis fluid containing sodium thiosulphate (STS).
    The International journal of artificial organs, 2014, Volume: 37, Issue:4

    Topics: Biomarkers; Calcium Chelating Agents; Coronary Artery Disease; Edetic Acid; Hemodialysis Solutions;

2014
[Calcific uremic arteriolopathy - treatment with sodium thiosulfate].
    Vnitrni lekarstvi, 2015, Volume: 61, Issue:2

    Topics: Calciphylaxis; Chelating Agents; Humans; Hyperparathyroidism, Secondary; Kidney Failure, Chronic; Ma

2015
[Calcific uremic arteriolopathy].
    Vnitrni lekarstvi, 2015, Volume: 61, Issue:2

    Topics: Calciphylaxis; Chelating Agents; Humans; Kidney Failure, Chronic; Male; Renal Dialysis; Thiosulfates

2015
Calcific uraemic arteriolopathy.
    BMJ case reports, 2015, Aug-27, Volume: 2015

    Topics: Adult; Arterioles; Calciphylaxis; Calcium; Chelating Agents; Female; Humans; Kidney Failure, Chronic

2015
Sodium thiosulfate protects brain in rat model of adenine induced vascular calcification.
    Neurochemistry international, 2015, Volume: 90

    Topics: Adenine; Animals; Antioxidants; Brain; Catalase; Disease Models, Animal; Glutathione Peroxidase; Kid

2015
Intralesional Sodium Thiosulfate to Treat Calciphylaxis.
    Actas dermo-sifiliograficas, 2016, Volume: 107, Issue:4

    Topics: Antioxidants; Calciphylaxis; Female; Humans; Middle Aged; Skin Diseases, Vascular; Thiosulfates; Vas

2016
The renal mitochondrial dysfunction in patients with vascular calcification is prevented by sodium thiosulfate.
    International urology and nephrology, 2016, Volume: 48, Issue:11

    Topics: Adenine; Animals; Antioxidants; Aorta; Apoptosis; Catalase; DNA Fragmentation; Glutathione; Glutathi

2016
The chemistry of thiosulfate and vascular calcification.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:2

    Topics: Animals; Aorta; Culture Media, Conditioned; Dose-Response Relationship, Drug; Durapatite; Male; Mode

2012
Successful treatment of calcific uremic arteriolopathy with sodium thiosulfate in a renal transplant recipient.
    Renal failure, 2012, Volume: 34, Issue:5

    Topics: Chelating Agents; Follow-Up Studies; Humans; Infusions, Intravenous; Kidney Transplantation; Male; M

2012
Maximal conservative therapy of calcific uremic ateriolopathy.
    Clinical nephrology, 2012, Volume: 78, Issue:1

    Topics: Arterioles; Calcimimetic Agents; Chelating Agents; Cinacalcet; Combined Modality Therapy; Diabetes M

2012