losartan has been researched along with Vascular Calcification in 2 studies
Losartan: An antagonist of ANGIOTENSIN TYPE 1 RECEPTOR with antihypertensive activity due to the reduced pressor effect of ANGIOTENSIN II.
losartan : A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since vascular calcification (VC) is commonly found in these diseases, the aim of this study was to examine whether or not losartan, a widely used angiotensin II receptor blockers, inhibits VC in rats in vivo." | 7.83 | Losartan Inhibits Vascular Calcification by Suppressing the BMP2 and Runx2 Expression in Rats In Vivo. ( Ke, Z; Li, D; Li, M; Shao, J; Wu, J; Wu, P, 2016) |
| "Objective To investigate the effect of the angiotensin II receptor 1 (AT1R) blocker losartan on vascular calcification in rat aortic artery and explore the underlying mechanisms." | 7.83 | [Mechanism of losartan suppressing vascular calcification in rat aortic artery]. ( Li, M; Shao, J; Wu, J; Wu, P, 2016) |
| "Objective To investigate the effect of the angiotensin II receptor 1 (AT1R) blocker losartan on vascular calcification in rat aortic artery and explore the underlying mechanisms." | 3.83 | [Mechanism of losartan suppressing vascular calcification in rat aortic artery]. ( Li, M; Shao, J; Wu, J; Wu, P, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, M | 2 |
| Wu, P | 2 |
| Shao, J | 2 |
| Ke, Z | 1 |
| Li, D | 1 |
| Wu, J | 2 |
2 other studies available for losartan and Vascular Calcification
| Article | Year |
|---|---|
Losartan Inhibits Vascular Calcification by Suppressing the BMP2 and Runx2 Expression in Rats In Vivo.
Topics: Angiotensin Receptor Antagonists; Animals; Bone Morphogenetic Protein 2; Core Binding Factor Alpha 1 | 2016 |
[Mechanism of losartan suppressing vascular calcification in rat aortic artery].
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Arteries; Blotting, Western; Bone Morph | 2016 |