chloroquine has been researched along with Vascular Calcification in 1 studies
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.
Vascular Calcification: Deposition of calcium into the blood vessel structures. Excessive calcification of the vessels are associated with ATHEROSCLEROTIC PLAQUES formation particularly after MYOCARDIAL INFARCTION (see MONCKEBERG MEDIAL CALCIFIC SCLEROSIS) and chronic kidney diseases which in turn increase VASCULAR STIFFNESS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vascular calcification is a pathologic response to mineral imbalances and is prevalent in atherosclerosis, diabetes mellitus, and chronic kidney disease." | 1.48 | Inhibition of endo-lysosomal function exacerbates vascular calcification. ( Cai, Y; Flores, AM; Guzman, RJ; Lin, T; Wang, XL, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, Y | 1 |
| Wang, XL | 1 |
| Flores, AM | 1 |
| Lin, T | 1 |
| Guzman, RJ | 1 |
1 other study available for chloroquine and Vascular Calcification
| Article | Year |
|---|---|
Inhibition of endo-lysosomal function exacerbates vascular calcification.
Topics: Animals; Aorta; Calcium; Cells, Cultured; Chloroquine; Endosomes; Hydrazones; Lysosomes; Male; Mice; | 2018 |