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2-chloroadenosine and 2-chloro-3'-deoxyadenosine

2-chloroadenosine has been researched along with 2-chloro-3'-deoxyadenosine in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.55)18.7374
1990's21 (47.73)18.2507
2000's16 (36.36)29.6817
2010's5 (11.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Koning, HP; Eze, AA; Gustavsson, AL; Hammarström, LG; Lundbäck, T; Olivera, GC; Rottenberg, ME; Sjöberg, B; Svensson, R; Vodnala, SK; Yeheskieli, E1
Phyliky, RL; Tefferi, A1
Rosowsky, A; Ruprecht, RM; Sodroski, JG; Solan, VC1
Hiraoka, W; Kuwabara, M; Matsuda, A; Sato, F; Tanabe, K; Ueda, T1
Bilgeri, R; Braunsteiner, H; Geisen, FH; Haun, M; Herold, M; Konwalinka, G; Petzer, AL; Zilian, U1
Estey, EH; Jaiyesimi, IA; Kantarjian, HM1
Lundberg, JH; Tefferi, A; Weitz, JJ; Witzig, TE1
Ames, MM; Li, CY; Reid, JM; Tefferi, A; Witzig, TE1
Boeck, G; Egle, A; Geisen, F; Greil, R; Gruber, J; Konwalinka, G; Sgonc, R; Villunger, A1
Cheson, BD1
Ambrosetti, A; Betticher, DC; Bürki, K; Cerny, T; Egger, T; Radford, JA; Rufener, B; Schmitz, SF; von Rohr, A; Zucca, E1
Enzenauer, RJ; Judson, PH1
Birtolo, S; Bocchia, M; Forconi, F; Lauria, F; Marotta, G; Raspadori, D; Rondelli, D; Salvucci, M; Tura, S; Ventura, MA; Zinzani, PL1
Knauf, W; Thiel, E; Zimmer-Molsberger, B1
Adamczyk-Cioch, M; Błasińska-Morawiec, M; Dmoszyńska, A; Dwilewicz-Trojaczek, M; Hellmann, A; Kazimierczak, M; Krykowski, E; Kuratowska, Z; Lewandowski, K; Nowak, WS; Robak, T; Skotnicki, AB; Trepińska, E; Urasiński, I; Zdziarska, B1
Mehta, A; Virchis, A1
Bolam, S; Orchard, JA; Oscier, DG1
Chrobák, L; Podzimek, K; Stránský, P; Zák, P1
Barak, V; Dinarello, CA; Nisman, B; Polliack, A; Vannier, E1
Amoroso, V; Baccarani, M; Beltrami, CA; Damiani, D; Di Loreto, C; Fanin, R; Infanti, L; Mariuzzi, L; Russo, D; Salmaso, F; Silvestri, F; Zaja, F1
Flandrin, G; Maloisel, F; Troussard, X1
Bacchi, M; Betticher, DC; Cerny, T; Hess, U; Ratschiller, D; Sperb, RA; Tichelli, A; Tobler, A; von Rohr, A1
Barak, V; Nisman, B; Polliack, A1
Bloński, JZ; Ceglarek, B; Dmoszyńska, A; Dwilewicz-Trojaczek, J; Grieb, P; Hansz, J; Hellmann, A; Holowiecki, J; Kasznicki, M; Komarnicki, M; Konopka, L; Kroll, R; Kuliczkowski, K; Lewandowski, K; Nowak, W; Potoczek, S; Robak, T; Skotnicki, AB; Soroka-Wojtaszko, M; Tomaszewska, A; Zdziarska, B1
Boehrer, S; Chow, KU; Hoelzer, D; Jantschke, P; Martin, H; Mitrou, PS; Napieralski, S; Pourebrahim, F; Ries, J; Rummel, MJ; Stein, J; Weidmann, E1
Gushiken, FC1
Dumontet, C; Galmarini, CM; Mackey, JR1
Al-Katib, AM; Beck, FW; Mohammad, RM; Wall, NR1
Blonski, JZ; Gora-Tybor, J; Lech-Miranda, E; Robak, T1
Abhyankar, D; Advani, SH; Bajpai, S; Gopal, R; Nair, CN; Saikia, T1
Bednarczyk, D; Kaca, W; Myszka, H; Najder, M1
Barge, RM; Honders, MW; Spoelder, HE; Veuger, MJ; Willemze, R1
Lucas, T; Samorapoompichit, P; Schedled, A; Sperr, WR; Steiner, M; Valent, P; Wachtler, F1
Caracciolo, F; Cecconi, N; Galimberti, S; Petrini, M; Riccioni, R1
Al-Katib, AM; Beck, FW; Dandashi, MH; Eilender, DS; Godmere, MA; Mohammad, RM; Siddiq, F; Snell, DC1
Ferrari, J; Lang, W; Müllauer, L; Raderer, M; Thurnher, S1
Januszewicz, H; Quach, H; Westerman, D1
Beauregard, P; Dufresne, J; Knecht, H; St-Hilaire, E; Viens, D1
Akı, Z; Deger, M; Konca, C; Özkurt, ZN; Yağcı, M1
Buda, G; Cecconi, N; Cervetti, G; Galimberti, S; Orciuolo, E; Petrini, M; Sordi, E1
Imamura, T; Kamizono, J; Kanegane, H; Kudo, K; Morimoto, A; Nakadate, H; Nakagawa, S; Sato, T; Shiota, Y; Tauchi, H1
Argnani, L; Baccarani, M; Broccoli, A; Derenzini, E; Gandolfi, L; Pellegrini, C; Pileri, S; Quirini, F; Stefoni, V; Zinzani, PL1
Baron, J; Lin, H; Penumalli, V; Rezania, K; Soliven, B; van Besien, K1

Reviews

6 review(s) available for 2-chloroadenosine and 2-chloro-3'-deoxyadenosine

ArticleYear
A clinical update on chronic lymphocytic leukemia. II. Critical analysis of current chemotherapeutic modalities.
    Mayo Clinic proceedings, 1992, Volume: 67, Issue:5

    Topics: 2-Chloroadenosine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Chlorambucil; Deoxyadenosines; Dose-Response Relationship, Drug; Histocompatibility Testing; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prednisone; Prognosis; Survival Rate; Vidarabine

1992
Advances in therapy for hairy cell leukemia. A review.
    Cancer, 1993, Jul-01, Volume: 72, Issue:1

    Topics: 2-Chloroadenosine; Deoxyadenosines; Forecasting; Granulocyte Colony-Stimulating Factor; Humans; Interferons; Leukemia, Hairy Cell; Male; Pentostatin; Splenectomy; Vidarabine

1993
Ennui or not ennui, that is the question...
    Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7, Issue:8

    Topics: 2-Chloroadenosine; Clinical Trials as Topic; Deoxyadenosines; Humans; Lymphoma, Non-Hodgkin

1996
Hairy cell leukemia. What is new forty years after the first description?
    Hematology and cell therapy, 1998, Volume: 40, Issue:4

    Topics: 2-Chloroadenosine; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Agents; B-Lymphocytes; Bone Marrow; Clinical Trials as Topic; Deoxyadenosines; Humans; Immunologic Factors; Interferon Type I; Leukemia, Hairy Cell; Neoplasm Proteins; Neoplasms, Second Primary; Neoplastic Stem Cells; Pentostatin; Receptors, Antigen, T-Cell, gamma-delta; Recombinant Proteins; Splenectomy; Vidarabine

1998
Nucleoside analogues: mechanisms of drug resistance and reversal strategies.
    Leukemia, 2001, Volume: 15, Issue:6

    Topics: 2-Chloroadenosine; 5'-Nucleotidase; Acute Disease; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Biological Transport; Carrier Proteins; Cytarabine; Cytidine Deaminase; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dioxolanes; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Neoplasm; Gemcitabine; Hematopoietic Cell Growth Factors; Humans; Leukemia, Myeloid; Lymphoproliferative Disorders; Neoplastic Stem Cells; Nucleosides; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Remission Induction; Ribonucleotide Reductases; Vidarabine

2001
Myasthenia gravis, an autoimmune manifestation of lymphoma and lymphoproliferative disorders: case reports and review of literature.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:3

    Topics: 2-Chloroadenosine; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cyclosporine; Deoxyadenosines; Fatal Outcome; Female; Humans; Lymphoma; Lymphoma, Follicular; Lymphoproliferative Disorders; Male; Middle Aged; Myasthenia Gravis; Paraneoplastic Syndromes, Nervous System; Prednisone; Pyridostigmine Bromide; Recurrence; Remission Induction; Rituximab; Waldenstrom Macroglobulinemia

2012

Trials

5 trial(s) available for 2-chloroadenosine and 2-chloro-3'-deoxyadenosine

ArticleYear
Phase I study of combined 2-chlorodeoxyadenosine and chlorambucil in chronic lymphoid leukemia and low-grade lymphoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1994, Volume: 12, Issue:3

    Topics: 2-Chloroadenosine; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Deoxyadenosines; Drug Administration Schedule; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Treatment Outcome

1994
2-chlorodeoxyadenosine (2-CDA) therapy in previously untreated patients with follicular stage III-IV non-Hodgkin's lymphoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1996, Volume: 7, Issue:8

    Topics: 2-Chloroadenosine; Adult; Aged; Base Sequence; Deoxyadenosines; Disease-Free Survival; Female; Gene Rearrangement; Genes, bcl-2; Humans; Infusion Pumps; Infusions, Intravenous; Injections, Subcutaneous; Lymphoma, Non-Hodgkin; Male; Middle Aged; Molecular Sequence Data; Neoplasm Staging; Polymerase Chain Reaction; Survival Rate; Treatment Outcome

1996
Long-lasting complete remission in patients with hairy cell leukemia treated with 2-CdA: a 5-year survey.
    Leukemia, 1997, Volume: 11, Issue:5

    Topics: 2-Chloroadenosine; Antimetabolites, Antineoplastic; Bone Marrow; Deoxyadenosines; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Hairy Cell; Male; Middle Aged; Neoplasms, Second Primary; Splenomegaly; Survival Rate; Time Factors

1997
Cladribine with or without prednisone in the treatment of previously treated and untreated B-cell chronic lymphocytic leukaemia - updated results of the multicentre study of 378 patients.
    British journal of haematology, 2000, Volume: 108, Issue:2

    Topics: 2-Chloroadenosine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Deoxyadenosines; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prednisone; Prospective Studies; Survival Analysis

2000
2-CdA in the treatment of hairy cell leukaemia.
    The Journal of the Association of Physicians of India, 2001, Volume: 49

    Topics: 2-Chloroadenosine; Adult; Antimetabolites, Antineoplastic; Deoxyadenosines; Female; Humans; Leukemia, Hairy Cell; Male; Middle Aged; Neutropenia; Survival Rate; Treatment Outcome

2001

Other Studies

33 other study(ies) available for 2-chloroadenosine and 2-chloro-3'-deoxyadenosine

ArticleYear
Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.
    Journal of medicinal chemistry, 2013, Dec-27, Volume: 56, Issue:24

    Topics: Animals; Cell Survival; Cells, Cultured; Deoxyadenosines; Dose-Response Relationship, Drug; Humans; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African

2013
Lymphoma, hairy-cell leukemia respond to new agents.
    Oncology (Williston Park, N.Y.), 1992, Volume: 6, Issue:9

    Topics: 2-Chloroadenosine; Antibodies, Monoclonal; Deoxyadenosines; Humans; Immunoconjugates; Immunotoxins; Leukemia, Hairy Cell; Lymphoma; Pentostatin; Ricin

1992
Synthesis of the 2-chloro analogues of 3'-deoxyadenosine, 2',3'-dideoxyadenosine, and 2',3'-didehydro-2',3'-dideoxyadenosine as potential antiviral agents.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:5

    Topics: 2-Chloroadenosine; Animals; Antiviral Agents; Deoxyadenosines; Dideoxyadenosine; Dideoxynucleosides; HIV; Humans; Mice; Structure-Activity Relationship

1989
Metabolic effects of 3'-deoxyadenosine (cordycepin) and 2-halo-3'-deoxyadenosine on repair of X-ray-induced potentially lethal damage in Chinese hamster V79 cells.
    Radiation research, 1988, Volume: 114, Issue:2

    Topics: 2-Chloroadenosine; Adenosine Kinase; Animals; Cell Line; Cricetinae; Cricetulus; Deoxyadenosines; DNA; DNA Damage; DNA Repair; Phosphotransferases

1988
Growth-inhibitory effect of 2-CdA on myeloid CFU-GM progenitors in normal human long-term bone marrow cultures and its compensation by G-CSF or IL-3.
    Experimental hematology, 1995, Volume: 23, Issue:6

    Topics: 2-Chloroadenosine; Bone Marrow; Cell Division; Cells, Cultured; Colony-Forming Units Assay; Deoxyadenosines; Drug Antagonism; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Interleukin-6

1995
Treatment of refractory T-cell chronic lymphocytic leukemia with purine nucleoside analogues.
    Leukemia & lymphoma, 1994, Volume: 14, Issue:1-2

    Topics: 2-Chloroadenosine; Anemia; Antineoplastic Combined Chemotherapy Protocols; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclophosphamide; Deoxyadenosines; Fatal Outcome; Female; Humans; Immunophenotyping; Leukemia, Prolymphocytic; Leukemia, Prolymphocytic, T-Cell; Male; Methotrexate; Middle Aged; Neoplastic Stem Cells; Prednisone; Salvage Therapy; Vidarabine; Vincristine; Zidovudine

1994
2',2'-Difluorodeoxycytidine (gemcitabine) induces apoptosis in myeloma cell lines resistant to steroids and 2-chlorodeoxyadenosine (2-CdA).
    Stem cells (Dayton, Ohio), 1996, Volume: 14, Issue:3

    Topics: 2-Chloroadenosine; Antimetabolites, Antineoplastic; Apoptosis; Biotin; Deoxyadenosines; Deoxycytidine; Deoxyuracil Nucleotides; Dexamethasone; DNA Damage; Drug Resistance; Gemcitabine; Glucocorticoids; Hematopoietic Stem Cells; Humans; Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sensitivity and Specificity; Staining and Labeling; Steroids; Tumor Cells, Cultured

1996
Purine analogues for treatment of refractory essential mixed cryoglobulinemia.
    Mayo Clinic proceedings, 1997, Volume: 72, Issue:1

    Topics: 2-Chloroadenosine; Cryoglobulinemia; Deoxyadenosines; Humans; Purines; Vidarabine

1997
Mycophenolate mofetil for severe autoimmune haemolytic anemia.
    Lancet (London, England), 1997, Oct-04, Volume: 350, Issue:9083

    Topics: 2-Chloroadenosine; Aged; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antimetabolites, Antineoplastic; Deoxyadenosines; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Male; Middle Aged; Mycophenolic Acid

1997
2-Chlorodeoxyadenosine (cladribine)-related eosinophilia in patients with lymphoproliferative diseases.
    European journal of haematology, 1997, Volume: 59, Issue:4

    Topics: 2-Chloroadenosine; Aged; Antimetabolites, Antineoplastic; Deoxyadenosines; Eosinophilia; Female; Humans; Infusions, Intravenous; Leukocyte Count; Lymphoproliferative Disorders; Male; Middle Aged; Retrospective Studies

1997
Splenic lymphoma with villous lymphocytes (SLVL) responding to 2-chlorodeoxyadenosine (2-CdA)
    British journal of haematology, 1998, Volume: 100, Issue:3

    Topics: 2-Chloroadenosine; Antimetabolites, Antineoplastic; Deoxyadenosines; Humans; Lymphoma; Splenectomy; Splenic Neoplasms

1998
Association of myelodysplastic changes with purine analogues.
    British journal of haematology, 1998, Volume: 100, Issue:4

    Topics: 2-Chloroadenosine; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Deoxyadenosines; Female; Humans; Lymphoproliferative Disorders; Male; Myelodysplastic Syndromes; Pentostatin; Vidarabine

1998
Red cell distribution width (RDW) as a marker of disease activity in patients with hairy cell leukemia.
    Acta medica (Hradec Kralove), 1998, Volume: 41, Issue:1

    Topics: 2-Chloroadenosine; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Deoxyadenosines; Erythrocyte Indices; Female; Hemoglobins; Humans; Interferon-alpha; Leukemia, Hairy Cell; Male; Middle Aged; Remission Induction; Splenectomy

1998
Correlation of serum levels of interleukin-1 family members with disease activity and response to treatment in hairy cell leukemia.
    European cytokine network, 1998, Volume: 9, Issue:1

    Topics: 2-Chloroadenosine; Antimetabolites, Antineoplastic; Deoxyadenosines; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1; Leukemia, Hairy Cell; Receptors, Interleukin-1; Receptors, Interleukin-1 Type II; Severity of Illness Index; Sialoglycoproteins

1998
BCL-2 immunohistochemical evaluation in B-cell chronic lymphocytic leukemia and hairy cell leukemia before treatment with fludarabine and 2-chloro-deoxy-adenosine.
    Leukemia & lymphoma, 1998, Volume: 28, Issue:5-6

    Topics: 2-Chloroadenosine; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Biomarkers, Tumor; Deoxyadenosines; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Proto-Oncogene Proteins c-bcl-2; Vidarabine

1998
[2-CDA in treatment of hairy cell leukemia: a comparison between intravenous and subcutaneous administration. Swiss Study Group of Applied Cancer Research].
    Schweizerische medizinische Wochenschrift, 1998, Oct-17, Volume: 128, Issue:42

    Topics: 2-Chloroadenosine; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Cohort Studies; Deoxyadenosines; Dose-Response Relationship, Drug; Drug Administration Schedule; Feasibility Studies; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia, Hairy Cell; Male; Middle Aged; Pilot Projects; Prospective Studies; Remission Induction; Treatment Outcome

1998
The tumor necrosis factor family and and correlation with disease activity and response to treatment in hairy cell leukemia.
    European journal of haematology, 1999, Volume: 62, Issue:2

    Topics: 2-Chloroadenosine; Antimetabolites, Antineoplastic; Biomarkers, Tumor; Deoxyadenosines; Humans; Leukemia, Hairy Cell; Neoplasm, Residual; Prognosis; Receptors, Tumor Necrosis Factor; Tumor Necrosis Factor-alpha

1999
Induction of apoptosis by 2-chloro-2'deoxyadenosine (2-CdA) alone and in combination with other cytotoxic drugs: synergistic effects on normal and neoplastic lymphocytes by addition of doxorubicin and mitoxantrone.
    Leukemia & lymphoma, 2000, Volume: 36, Issue:5-6

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Apoptosis; Deoxyadenosines; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Humans; Lymphoma; Mitoxantrone; Tumor Cells, Cultured

2000
Peliosis hepatis after treatment with 2-chloro-3'-deoxyadenosine.
    Southern medical journal, 2000, Volume: 93, Issue:6

    Topics: 2-Chloroadenosine; Aged; Antineoplastic Agents; Deoxyadenosines; Female; Humans; Leukemia, Hairy Cell; Peliosis Hepatis

2000
Treatment-induced expression of anti-apoptotic proteins in WSU-CLL, a human chronic lymphocytic leukemia cell line.
    Journal of drug targeting, 2001, Volume: 9, Issue:5

    Topics: 2-Chloroadenosine; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Bryostatins; Deoxyadenosines; Enzyme Activators; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured

2001
2-chlorodeoxyadenosine (2-CdA) does not change the expression of Fas antigen on chronic lymphocytic leukaemia cells.
    Advances in experimental medicine and biology, 2000, Volume: 486

    Topics: 2-Chloroadenosine; Antimetabolites, Antineoplastic; Deoxyadenosines; fas Receptor; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Tumor Cells, Cultured

2000
Synthesis and induction of apoptosis in B cell chronic leukemia by diosgenyl 2-amino-2-deoxy-beta-D-glucopyranoside hydrochloride and its derivatives.
    Carbohydrate research, 2003, Jan-20, Volume: 338, Issue:2

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Deoxyadenosines; Diosgenin; Glucosamine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Saponins; Structure-Activity Relationship

2003
Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.
    Leukemia research, 2003, Volume: 27, Issue:5

    Topics: 2-Chloroadenosine; Alternative Splicing; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Biological Transport; Buthionine Sulfoximine; Calcium Channel Blockers; Cytarabine; Daunorubicin; Decitabine; Deoxyadenosines; Deoxycytidine Kinase; DNA Mutational Analysis; DNA, Neoplasm; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glutathione; Humans; Idarubicin; Leukemia; Methotrexate; Neoplasm Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Verapamil

2003
Induction of apoptosis in the human mast cell leukemia cell line HMC-1 by various antineoplastic drugs.
    Leukemia & lymphoma, 2003, Volume: 44, Issue:3

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Apoptosis; Cisplatin; Cytarabine; Deoxyadenosines; DNA Fragmentation; Doxorubicin; Endodeoxyribonucleases; Etoposide; Humans; In Situ Nick-End Labeling; Leukemia, Mast-Cell; Microscopy, Electron; Neoplasm Proteins; Tumor Cells, Cultured; Vidarabine; Vincristine

2003
Low dose 2-CdA schedule activity in splenic marginal zone lymphomas.
    Hematological oncology, 2003, Volume: 21, Issue:4

    Topics: 2-Chloroadenosine; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Deoxyadenosines; Female; Humans; Lymphoma; Middle Aged; Splenectomy; Splenic Neoplasms; Survival Analysis; Treatment Outcome

2003
Factors affecting bryostatin 1-enhanced 2-CdA cytotoxicity in resistant B-cell chronic lymphocytic leukemia.
    International journal of molecular medicine, 2004, Volume: 14, Issue:1

    Topics: 2-Chloroadenosine; 5'-Nucleotidase; Antimetabolites, Antineoplastic; Bryostatins; Cell Death; Deoxyadenosines; Deoxycytidine Kinase; DNA-Activated Protein Kinase; DNA-Binding Proteins; Drug Resistance, Neoplasm; Drug Synergism; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Nuclear Proteins; Protein Serine-Threonine Kinases; ras Proteins; Tumor Cells, Cultured

2004
Bilateral facial nerve palsy as first indication of relapsing hairy cell leukemia after 36 years.
    Neurology, 2004, Jul-27, Volume: 63, Issue:2

    Topics: 2-Chloroadenosine; Aged; Antimetabolites, Antineoplastic; Arm; Deoxyadenosines; Diagnosis, Differential; Diplopia; Facial Paralysis; Female; Humans; Hypesthesia; Leukemia, Hairy Cell; Lymph Nodes; Recurrence; Remission Induction; Stroke; Survivors

2004
Complete remission of hairy cell leukemia variant (HCL-v) complicated by red cell aplasia post treatment with rituximab.
    Haematologica, 2005, Volume: 90 Suppl

    Topics: 2-Chloroadenosine; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood Transfusion; Combined Modality Therapy; Cyclophosphamide; Deoxyadenosines; Disease Progression; Drug Resistance, Neoplasm; Fatal Outcome; Humans; Interferon-alpha; Leukemia, Hairy Cell; Male; Neoplasms, Second Primary; Prednisolone; Recurrence; Red-Cell Aplasia, Pure; Remission Induction; Rituximab; Splenectomy; Urinary Bladder Neoplasms

2005
Successful treatment of warm antibody (IgG/C3 positive) autoimmune hemolytic anemia in hairy-cell leukemia with 2-CdA in the elderly.
    Leukemia & lymphoma, 2008, Volume: 49, Issue:7

    Topics: 2-Chloroadenosine; Aged, 80 and over; Anemia, Hemolytic, Autoimmune; Antimetabolites, Antineoplastic; Deoxyadenosines; Female; Humans; Leukemia, Hairy Cell; Treatment Outcome

2008
Extranodal multifocal Rosai-Dorfman disease: response to 2-chlorodeoxyadenosine treatment.
    International journal of hematology, 2009, Volume: 89, Issue:1

    Topics: 2-Chloroadenosine; Adult; Deoxyadenosines; Histiocytosis, Sinus; Humans; Lymphatic Diseases; Lymphoma, Non-Hodgkin; Male; Remission Induction; Spinal Cord Compression

2009
Significant efficacy of 2-CdA with or without rituximab in the treatment of splenic marginal zone lymphoma (SMZL).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2010, Volume: 21, Issue:4

    Topics: 2-Chloroadenosine; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Deoxyadenosines; Disease-Free Survival; Female; Humans; Lymphoma, B-Cell, Marginal Zone; Male; Middle Aged; Remission Induction; Retrospective Studies; Rituximab; Splenic Neoplasms; Treatment Outcome

2010
Outcome of pediatric patients with Langerhans cell histiocytosis treated with 2 chlorodeoxyadenosine: a nationwide survey in Japan.
    International journal of hematology, 2010, Volume: 91, Issue:4

    Topics: 2-Chloroadenosine; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Data Collection; Deoxyadenosines; Drug Resistance, Neoplasm; Female; Histiocytosis, Langerhans-Cell; Humans; Infant; Infant, Newborn; Japan; Male; Surveys and Questionnaires; Treatment Outcome

2010
Hairy cell leukemia: evaluation of the long-term outcome in 121 patients.
    Cancer, 2010, Oct-15, Volume: 116, Issue:20

    Topics: 2-Chloroadenosine; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Deoxyadenosines; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Leukemia, Hairy Cell; Male; Middle Aged; Retreatment; Splenectomy; Treatment Outcome

2010