2-chloroadenosine has been researched along with 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine in 39 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 26 (66.67) | 18.2507 |
2000's | 12 (30.77) | 29.6817 |
2010's | 1 (2.56) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Berkich, DA; Dean, RL; Eveleth, D; Hiramatsu, K; Jacobson, KA; Ji, XD; Kassell, NF; Lee, KS; Nikodijevic, O; van Galen, PJ | 1 |
Jacobson, KA; van Galen, PJ; Williams, M | 1 |
Arroyo, LH; Olsson, RA; Thompson, RD; Ueeda, M | 1 |
Jacobson, KA; Kim, J; Schöneberg, T; van Rhee, AM; Wess, J | 1 |
Jacobson, KA; Ji, XD; Kim, HO; Olah, ME; Siddiqi, SM; Stiles, GL | 1 |
Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U | 1 |
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T | 1 |
Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW | 1 |
Brown, ML; Linden, J; Macdonald, TL; Rieger, JM; Sullivan, GW | 1 |
Bertarelli, DC; Borrmann, T; Florin, NC; Hinz, S; Li, W; Müller, CE; Scheiff, AB | 1 |
de Lera Ruiz, M; Lim, YH; Zheng, J | 1 |
Makujina, SR; Mustafa, SJ | 1 |
Burnstock, G; Ralevic, V; Rubino, A | 1 |
Brunelleschi, S; Dianzani, C; Fantozzi, R; Viano, I | 1 |
Alexander, SP; Hill, SJ; Kendall, DA; Losinski, A | 1 |
Blazynski, C; McIntosh, HH | 1 |
Cunha, RA; Milusheva, E; Ribeiro, JA; Sebastião, AM; Vizi, ES | 1 |
Broad, RM; Fredholm, BB | 1 |
Constantino, MD; Cunha, RA; Fredholm, BB; Johansson, B; Sebastião, AM | 1 |
Anderson, GF; Barraco, RA; Helfman, CC; Zhong, H | 1 |
Fredholm, BB; Jin, S | 1 |
Monteiro, EC; Monteiro, TC; Silva e Sousa, MA; Vera-Cruz, P | 1 |
Abebe, W; Mustafa, SJ | 1 |
Neher, M; Schneider, A; Schwaninger, M; Spranger, M; Viegas, E | 1 |
Ali, S; Metzger, WJ; Mustafa, SJ; Olanrewaju, HA | 1 |
Alexander, SP; Cooper, J; Hill, SJ | 1 |
Dubey, RK; Gillespie, DG; Jackson, EK | 1 |
Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z | 1 |
Cunha, RA; Gonçalves, ML; Ribeiro, JA | 1 |
Henry, JL; Li, H | 1 |
Dubey, RK; Gillespie, DG; Jackson, EK; Shue, H | 1 |
Feoktistov, I; Mustafa, SJ; Olanrewaju, HA; Qin, W; Scemama, JL | 1 |
Hourani, SM; Prentice, DJ | 1 |
Flood, A; Headrick, JP | 1 |
Morrison, RR; Mustafa, SJ; Talukder, MA | 1 |
Flood, AJ; Headrick, JP; Willems, L | 1 |
Hague, BF; Kindt, TJ; Zhao, TM | 1 |
Carroll, MA; Falck, JR; Ferreri, NR; Liclican, EL; McGiff, JC; Pedraza, PL | 1 |
Hendrich, KS; Ho, C; Jackson, EK; Janesko, KL; Kochanek, PM; Melick, JA; Shore, PM; Wisniewski, SR; Zacharia, L | 1 |
2 review(s) available for 2-chloroadenosine and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine
Article | Year |
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Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
Adenosine A2A receptor as a drug discovery target.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction | 2014 |
37 other study(ies) available for 2-chloroadenosine and 2-(4-(2-carboxyethyl)phenethylamino)-5'-n-ethylcarboxamidoadenosine
Article | Year |
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Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists.
Topics: Adenosine; Animals; Body Temperature; Brain; Evoked Potentials; Gerbillinae; In Vitro Techniques; Lipolysis; Male; Mice; Motor Activity; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Solubility; Structure-Activity Relationship; Sulfonic Acids | 1992 |
2-Alkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor.
Topics: Adenosine; Animals; Atrioventricular Node; Coronary Vessels; Guinea Pigs; Heart; In Vitro Techniques; Models, Molecular; Molecular Conformation; Molecular Structure; Muscle, Smooth, Vascular; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1991 |
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1; Structure-Activity Relationship | 1995 |
2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Brain; Cell Membrane; CHO Cells; Cricetinae; Molecular Structure; Rats; Receptors, Purinergic P1; Recombinant Proteins; Structure-Activity Relationship | 1994 |
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium | 1999 |
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines | 1999 |
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2000 |
Design, synthesis, and evaluation of novel A2A adenosine receptor agonists.
Topics: Alkynes; Animals; Cerebral Cortex; Combinatorial Chemistry Techniques; Corpus Striatum; Crystallography, X-Ray; Drug Design; Furans; In Vitro Techniques; Ligands; Models, Molecular; Purinergic P1 Receptor Agonists; Purines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Regression Analysis; Structure-Activity Relationship | 2001 |
1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.
Topics: Adenosine A2 Receptor Antagonists; Animals; Drug Design; Humans; Kinetics; Ligands; Mice; Protein Binding; Radioligand Assay; Rats; Receptor, Adenosine A2B; Xanthines | 2009 |
Adenosine-5'-uronamides rapidly desensitize the adenosine A2 receptor in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Coronary Vessels; Cyclohexanes; Humans; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Receptors, Purinergic P1; Structure-Activity Relationship; Swine; Tachyphylaxis | 1993 |
Contribution of P1-(A2b subtype) and P2-purinoceptors to the control of vascular tone in the rat isolated mesenteric arterial bed.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Adenosine modulation of primed human neutrophils.
Topics: 2-Chloroadenosine; Adenosine; Antihypertensive Agents; Drug Interactions; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenethylamines; Receptors, Purinergic P1; Superoxides; Theophylline | 1994 |
A comparison of A2 adenosine receptor-induced cyclic AMP generation in cerebral cortex and relaxation of pre-contracted aorta.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Cerebral Cortex; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1994 |
Characterization and localization of adenosine A2 receptors in bovine rod outer segments.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cattle; Electrophoresis, Polyacrylamide Gel; Phenethylamines; Receptors, Purinergic P1; Rod Cell Outer Segment; Subcellular Fractions; Tissue Distribution | 1994 |
Excitatory and inhibitory effects of A1 and A2A adenosine receptor activation on the electrically evoked [3H]acetylcholine release from different areas of the rat hippocampus.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Antihypertensive Agents; Cerebellar Nuclei; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Male; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Tritium; Xanthines | 1994 |
A1, but not A2A, adenosine receptors modulate electrically stimulated [14C]acetylcholine release from rat cortex.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Cerebral Cortex; Electric Stimulation; In Vitro Techniques; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 1996 |
Evidence for high-affinity binding sites for the adenosine A2A receptor agonist [3H] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Xanthines | 1996 |
The effects of 5'-N-ethylcarboxamidoadenosine on evoked release of [3H]serotonin in the rat nucleus tractus solitarius.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Antihypertensive Agents; Binding, Competitive; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; Male; Neurotransmitter Agents; Organ Culture Techniques; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Sensitivity and Specificity; Serotonin; Solitary Nucleus; Tritium; Vasodilator Agents; Xanthines | 1996 |
Adenosine A2A receptor stimulation increases release of acetylcholine from rat hippocampus but not striatum, and does not affect catecholamine release.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Catecholamines; Corpus Striatum; Hippocampus; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Xanthines | 1997 |
Adenosine increases the cAMP content of the rat carotid body in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenine; Adenosine; Animals; Carotid Body; Cyclic AMP; Male; Nerve Tissue Proteins; Perfusion; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Second Messenger Systems | 1996 |
Effect of low density lipoprotein on adenosine receptor-mediated coronary vasorelaxation in vitro.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; In Vitro Techniques; Lipoproteins, LDL; Male; Nitrites; Oxidation-Reduction; Phenethylamines; Receptors, Purinergic P1; Swine; Vasodilation | 1997 |
Stimulation of interleukin-6 secretion and gene transcription in primary astrocytes by adenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Animals, Newborn; Astrocytes; Cerebral Cortex; Genes, Reporter; Humans; Interleukin-6; Kinetics; Mice; Phenethylamines; Purinergic P1 Receptor Agonists; Recombinant Fusion Proteins; Transcription, Genetic | 1997 |
Adenosine receptor-mediated relaxation of rabbit airway smooth muscle: a role for nitric oxide.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Bronchi; Dose-Response Relationship, Drug; Epithelium; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenethylamines; Potassium Chloride; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Purinergic P1 | 1997 |
An endogenous A2B adenosine receptor coupled to cyclic AMP generation in human embryonic kidney (HEK 293) cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cells, Cultured; Cyclic AMP; DNA, Complementary; Gene Amplification; Humans; In Vitro Techniques; Kidney; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2B; Receptors, Purinergic P1; Triazoles | 1997 |
Cyclic AMP-adenosine pathway induces nitric oxide synthesis in aortic smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Aorta, Thoracic; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dideoxyadenosine; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Signal Transduction; Thionucleotides | 1998 |
Adenosine inhibits growth of human aortic smooth muscle cells via A2B receptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adult; Animals; Aorta, Thoracic; Cell Division; Cells, Cultured; Collagen; Dipyridamole; DNA; Humans; Kinetics; Male; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A2B; Receptors, Purinergic P1; Thymidine; Xanthines | 1998 |
Adenosine A2A receptors facilitate 45Ca2+ uptake through class A calcium channels in rat hippocampal CA3 but not CA1 synaptosomes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Hippocampus; Male; omega-Agatoxin IVA; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Spider Venoms; Synaptosomes; Veratridine; Xanthines | 1997 |
Adenosine A2 receptor mediation of pre- and postsynaptic excitatory effects of adenosine in rat hippocampus in vitro.
Topics: 2-Chloroadenosine; Adenosine; Animals; Excitatory Postsynaptic Potentials; Female; Hippocampus; Male; Phenethylamines; Rats; Receptors, Purinergic P1; Synaptic Transmission; Tetrodotoxin | 1998 |
A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticoagulants; Antihypertensive Agents; Aorta, Abdominal; Becaplermin; Cell Division; Dinucleoside Phosphates; Enzyme Inhibitors; Hyperplasia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phenethylamines; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Thymidine; Tritium; Tubercidin; Vasodilator Agents; Xanthines | 2000 |
Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; Binding, Competitive; Cells, Cultured; Coronary Vessels; Cyclic AMP; Endothelium, Vascular; Gene Expression Regulation; Humans; Iodine Radioisotopes; Iodobenzenes; Kinetics; Phenethylamines; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Swine; Transcription, Genetic; Triazines; Triazoles | 2000 |
Characterisation of adenosine receptors mediating relaxation in hamster isolated aorta.
Topics: 2-Chloroadenosine; Adenosine; Animals; Aorta; Cricetinae; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mesocricetus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenethylamines; Receptors, Purinergic P1; Theophylline; Thioinosine; Vasodilation | 2000 |
Functional characterization of coronary vascular adenosine receptors in the mouse.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Heart; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitroarginine; Phenethylamines; Potassium Channel Blockers; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Vascular Resistance; Vasodilation; Vasodilator Agents | 2001 |
Comparison of the vascular effects of adenosine in isolated mouse heart and aorta.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Heart; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Perfusion; Phenethylamines | 2002 |
Coronary function and adenosine receptor-mediated responses in ischemic-reperfused mouse heart.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Animals; Caffeine; Coronary Circulation; Heart; Male; Mice; Mice, Inbred C57BL; Models, Animal; Myocardial Contraction; Myocardial Reperfusion Injury; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Antagonists; Vasodilator Agents; Xanthines | 2002 |
Binding of HTLV-1 virions to T cells occurs by a temperature and calcium-dependent process and is blocked by certain type 2 adenosine receptor antagonists.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antibodies, Monoclonal; Calcium; Cations, Divalent; Cell Line, Transformed; Human T-lymphotropic virus 1; Humans; Kinetics; Membrane Microdomains; Phenethylamines; Purinergic P1 Receptor Agonists; Quinazolines; T-Lymphocytes; Thermodynamics; Triazoles | 2003 |
Exaggerated response to adenosine in kidneys from high salt-fed rats: role of epoxyeicosatrienoic acids.
Topics: 2-Chloroadenosine; 8,11,14-Eicosatrienoic Acid; Adenosine; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney; Male; Perfusion; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Renal Circulation; Sodium, Dietary; Vasodilation | 2005 |
Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonance imaging.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Brain Injuries; Cerebrovascular Circulation; Magnetic Resonance Imaging; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Spin Labels; Trauma Severity Indices | 2005 |