Page last updated: 2024-09-27

Histiocytosis, Sinus

Benign, non-Langerhans-cell, histiocytic proliferative disorder that primarily affects the lymph nodes. It is often referred to as sinus histiocytosis with massive lymphadenopathy.

Synonyms(1)

Synonym
Histiocytosis, Sinus

Research

Studies (198)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's21 (10.61)12.5806
2000's52 (26.26)18.1394
2010's85 (42.93)28.8240
2020's40 (20.20)9.53
DrugIndicatedRelationship StrengthStudiesTrials
aminolevulinic acid0low20
formaldehyde0low10
nitrous oxide0low10
azathioprine0low20
cyclopentolate0low10
dapsone0low50
fentanyl0low10
iohexol0low10
iomeprol0low10
isoflurane0low10
khellin0low10
midazolam0low10
ofloxacin0low10
procarbazine0low10
propofol0low10
sevoflurane0low20
thalidomide0low130
prednisolone0low190
thyroxine0low30
prednisone0low200
cytarabine0low20
dinitrofluorobenzene0low10
triamcinolone acetonide0low30
methylprednisolone0low70
meglumine0low10
2-chloroadenosine0low10
betamethasone0low10
cladribine0low20
titanium0low10
chromium0low10
gadolinium0low10
trolamine salicylate0low60
triamcinolone0low10
etoposide0low10
propiconazole0low120
imiquimod0low10
iopamidol0low10
fluorodeoxyglucose f180low310
bexarotene0low10
fibrinogen0low10
cobalt0low10
clofarabine0low40
imatinib mesylate0low20
methotrexate0low170
cortisone0low10
inositol 3-phosphate0low10
rocuronium0low10
melphalan0low10
bromochloroacetic acid0low10
mercaptopurine0low20
2-chloro-3'-deoxyadenosine0low10
calcitriol0low10
isotretinoin0low20
phenylephrine hydrochloride0low50
acitretin0low20
sirolimus0low30
clobetasol0low10
gadolinium dtpa0low10
trametinib0low10
jaw0low10
gdc-09730low30
technetium tc 99m sestamibi0low10
sodium pertechnetate tc 99m0low10
chiniofon0low10
piperidines0low20
dabrafenib0low10
roquinimex0low10
cyclin d10medium31
lewis x antigen0low10
cyclosporine0low20
technetium tc 99m medronate0low10
muramidase0low20
exudates0low10
acyclovir0low10
eye0low20

Protein Targets (866)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE100010
Chain A, Beta-lactamase6006
glp-1 receptor, partial110011
TDP1 protein300030
Smad37007
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)9009
NPYLR7B0011
67.9K protein9009
IDH1110011
cellular tumor antigen p53 isoform a5005
vasopressin V1b receptor1001
nuclear factor erythroid 2-related factor 2 isoform 2130013
glycogen synthase kinase-3 beta isoform 10011
mitogen-activated protein kinase 13003
flap endonuclease 16006
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
DNA polymerase iota isoform a (long)9009
urokinase-type plasminogen activator precursor7007
plasminogen precursor7007
urokinase plasminogen activator surface receptor precursor7007
geminin240024
survival motor neuron protein isoform d100010
relaxin receptor 1 isoform 12002
high affinity choline transporter 1 isoform a0101
relaxin receptor 2 isoform 11001
lamin isoform A-delta10160016
cGMP-dependent 3',5'-cyclic phosphodiesterase0303
Renin0101
Integrin beta-34004
Heat shock protein HSP 90-alpha0213
Integrin alpha-IIb4004
Adenosine receptor A30314
Endoplasmin0112
Adenosine receptor A10203
Adenosine receptor A10101
5-hydroxytryptamine receptor 2A0101
Adenosine receptor A30202
Adenosine receptor A2a0315
Adenosine receptor A2b0113
Adenosine receptor A2b0204
Adenosine receptor A10102
Adenosine receptor A2a0204
Adenosine receptor A2a0011
Adenosine receptor A10011
Adenosine deaminase 0101
Adenylate cyclase type 50101
Ataxin-2180018
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Luciferase7007
USP1 protein, partial130013
Microtubule-associated protein tau6006
AR protein300030
aldehyde dehydrogenase 1 family, member A1140014
glucocorticoid receptor [Homo sapiens]250025
estrogen nuclear receptor alpha320032
peroxisome proliferator activated receptor gamma150015
euchromatic histone-lysine N-methyltransferase 2210021
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a190019
vitamin D3 receptor isoform VDRA6006
thyroid hormone receptor beta isoform 2180018
serine/threonine-protein kinase PLK13003
eyes absent homolog 2 isoform a1001
DNA polymerase eta isoform 14004
peripheral myelin protein 22140014
histone acetyltransferase KAT2A isoform 16006
ATP-binding cassette sub-family C member 3023023
Multidrug resistance-associated protein 4023024
Bile salt export pump0505
Bile salt export pump028028
Rap guanine nucleotide exchange factor 32002
Cellular tumor antigen p53250025
Rap guanine nucleotide exchange factor 43003
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain8008
Thymidine kinase 0101
thioredoxin reductase130013
phosphopantetheinyl transferase7007
GLS protein5005
thyroid stimulating hormone receptor4004
EWS/FLI fusion protein170017
arylsulfatase A6006
activating transcription factor 69009
Histone H2A.x120012
Bloom syndrome protein isoform 19009
hemoglobin subunit beta4004
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Solute carrier family 22 member 1 0203
Solute carrier family 22 member 60001
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0102
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0708
Cytochrome P450 2J20303
Disintegrin and metalloproteinase domain-containing protein 171001
Purine nucleoside phosphorylase0022
Solute carrier family 22 member 60002
Thymidine kinase 0101
Solute carrier family 22 member 80002
Canalicular multispecific organic anion transporter 1023024
Thymidine kinase0202
bromodomain adjacent to zinc finger domain 2B4004
Gamma-aminobutyric acid receptor subunit rho-10101
Glutamate receptor 10101
Glutamate receptor 20101
Glutamate receptor 30101
Glutamate receptor ionotropic, kainate 30101
Solute carrier family 15 member 10101
Glutamate receptor 40101
Solute carrier family 15 member 10101
Solute carrier family 15 member 20101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
interleukin 84004
acetylcholinesterase7007
RAR-related orphan receptor gamma220022
SMAD family member 28008
ATAD5 protein, partial8008
Fumarate hydratase8008
SMAD family member 38008
GLI family zinc finger 3240024
thioredoxin glutathione reductase6006
nuclear receptor subfamily 1, group I, member 3200020
retinoic acid nuclear receptor alpha variant 1190019
retinoid X nuclear receptor alpha170017
estrogen-related nuclear receptor alpha250025
farnesoid X nuclear receptor150015
pregnane X nuclear receptor240024
G120012
polyprotein8008
P531001
peroxisome proliferator-activated receptor delta150015
aryl hydrocarbon receptor140014
thyroid stimulating hormone receptor8008
v-jun sarcoma virus 17 oncogene homolog (avian)9009
peripheral myelin protein 22 isoform 15005
heat shock protein beta-19009
nuclear factor erythroid 2-related factor 2 isoform 1210021
cytochrome P450 3A4 isoform 17007
M-phase phosphoprotein 83003
muscleblind-like protein 1 isoform 17007
muscarinic acetylcholine receptor M13003
Gamma-aminobutyric acid receptor subunit pi73111
Voltage-dependent calcium channel gamma-2 subunit150015
Interferon beta160016
HLA class I histocompatibility antigen, B alpha chain 120012
Gamma-aminobutyric acid receptor subunit beta-173111
Gamma-aminobutyric acid receptor subunit delta73111
Gamma-aminobutyric acid receptor subunit gamma-273111
Glutamate receptor 2150015
Gamma-aminobutyric acid receptor subunit alpha-573111
Gamma-aminobutyric acid receptor subunit alpha-373111
Gamma-aminobutyric acid receptor subunit gamma-173111
Gamma-aminobutyric acid receptor subunit alpha-273111
Gamma-aminobutyric acid receptor subunit alpha-473111
Gamma-aminobutyric acid receptor subunit gamma-373111
Gamma-aminobutyric acid receptor subunit alpha-673111
Nuclear receptor ROR-gamma6006
Gamma-aminobutyric acid receptor subunit alpha-173111
Gamma-aminobutyric acid receptor subunit beta-373111
Gamma-aminobutyric acid receptor subunit beta-273111
GABA theta subunit73111
Inositol hexakisphosphate kinase 1120012
ATPase family AAA domain-containing protein 5160016
Gamma-aminobutyric acid receptor subunit epsilon73111
Protein-arginine deiminase type-40202
cytochrome P450 2C9, partial120012
pregnane X receptor6006
progesterone receptor160016
cytochrome P450 family 3 subfamily A polypeptide 4160016
vitamin D (1,25- dihydroxyvitamin D3) receptor130013
nuclear receptor subfamily 1, group I, member 26006
thyroid hormone receptor beta isoform a6006
galanin receptor type 30101
Glucocorticoid receptor014221
Glycine receptor subunit alpha-1014014
Glycine receptor subunit beta014014
Glycine receptor subunit alpha-2014014
Glycine receptor subunit alpha-3014014
ORF730011
hypoxia-inducible factor 1 alpha subunit8008
PPM1D protein5005
caspase 7, apoptosis-related cysteine protease5005
estrogen receptor 2 (ER beta)9009
caspase-35005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
thyrotropin-releasing hormone receptor1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
Caspase-73003
caspase-33003
nuclear receptor ROR-gamma isoform 18008
Cytochrome P450 26A10101
Cytochrome P450 1A20304
Cytochrome P450 3A409011
Retinoic acid receptor alpha0123
Retinoic acid receptor beta0123
Retinoic acid receptor gamma 0123
Retinoic acid receptor RXR-alpha0258
Retinoic acid receptor RXR-alpha0112
Retinoic acid receptor RXR-beta0112
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Type-1 angiotensin II receptor0011
Nuclear receptor subfamily 4 group A member 20011
Retinoic acid receptor RXR-gamma0112
Type-2 angiotensin II receptor0011
Oxysterols receptor LXR-beta0011
Spike glycoprotein110011
Retinoic acid receptor RXR-alpha0011
Oxysterols receptor LXR-alpha0011
Sigma non-opioid intracellular receptor 10303
Cytochrome P450 26B10101
Chain A, Vitamin D Nuclear Receptor0011
Vitamin D3 receptor0011
Vitamin D-binding protein0011
Androgen receptor0303
Cytochrome P450 2D60202
Vitamin D3 receptor0124
Vitamin D3 receptor0113
Cytochrome P450 2C190303
Kappa-type opioid receptor0213
Vitamin D3 receptor0011
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
Chain A, BCL-2-RELATED PROTEIN A10011
huntingtin isoform 22002
tyrosine-protein kinase Yes1001
bcl-2-like protein 11 isoform 10011
Deoxycytidine kinase0046
endonuclease IV3003
dopamine D1 receptor2002
regulator of G-protein signaling 42002
chromobox protein homolog 19009
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0202
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 435005
Multidrug and toxin extrusion protein 10101
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0303
serine/threonine-protein kinase mTOR isoform 14004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
transactivating tegument protein VP16 [Human herpesvirus 1]0303
nuclear receptor coactivator 3 isoform a0303
Thymidine kinase 2, mitochondrial0101
Thymidine kinase0101
Thymidylate synthase0304
Thymidine kinase0101
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
D(1A) dopamine receptor1001
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Deoxynucleoside kinase0101
ATP-dependent phosphofructokinase5005
Bone morphogenetic protein receptor type-1B0044
Membrane-associated progesterone receptor component 10033
Cell division cycle 7-related protein kinase0033
Serine/threonine-protein kinase PLK40044
ATP-dependent RNA helicase DDX3X0044
Pirin0101
Pyridoxal kinase0044
Citron Rho-interacting kinase0044
Serine/threonine-protein kinase Chk10044
Aurora kinase A0044
Cyclin-G-associated kinase0044
Ephrin type-B receptor 60044
Peroxisomal acyl-coenzyme A oxidase 30044
Receptor-interacting serine/threonine-protein kinase 20145
Mitotic checkpoint serine/threonine-protein kinase BUB10044
Dynamin-like 120 kDa protein, mitochondrial0044
Tyrosine-protein kinase JAK20033
Eukaryotic translation initiation factor 5B0044
Rho-associated protein kinase 20044
Serine/threonine-protein kinase ULK10044
Serine/threonine-protein kinase/endoribonuclease IRE10044
Nuclear receptor subfamily 1 group I member 20055
Ribosomal protein S6 kinase alpha-50044
U5 small nuclear ribonucleoprotein 200 kDa helicase0044
Ribosomal protein S6 kinase alpha-40044
Serine/threonine-protein kinase 160044
Cyclin-dependent kinase-like 50044
Serine/threonine-protein kinase 100044
Serine/threonine-protein kinase D30044
Structural maintenance of chromosomes protein 20044
Mitogen-activated protein kinase kinase kinase 60044
Mitogen-activated protein kinase kinase kinase kinase 40044
Serine/threonine-protein kinase LATS10044
Serine/threonine-protein kinase PAK 40044
Tyrosine-protein kinase ABL10168
Epidermal growth factor receptor0145
GTPase KRas0101
RAF proto-oncogene serine/threonine-protein kinase0102
High affinity nerve growth factor receptor0044
Guanine nucleotide-binding protein G(i) subunit alpha-20022
ADP/ATP translocase 20044
Protein kinase C beta type0044
Insulin receptor0044
Tyrosine-protein kinase Lck0044
Tyrosine-protein kinase Fyn0044
Cyclin-dependent kinase 10044
Glycogen phosphorylase, liver form0044
Tyrosine-protein kinase Fes/Fps0044
Adenine phosphoribosyltransferase0033
Tyrosine-protein kinase Yes0044
Tyrosine-protein kinase Lyn0044
Proto-oncogene tyrosine-protein kinase receptor Ret0044
Insulin-like growth factor 1 receptor0044
Signal recognition particle receptor subunit alpha0044
Cytochrome c1, heme protein, mitochondrial0044
Hepatocyte growth factor receptor0044
Tyrosine-protein kinase HCK0044
Platelet-derived growth factor receptor beta0044
Tyrosine-protein kinase Fgr0033
Serine/threonine-protein kinase A-Raf0145
Glycogen phosphorylase, brain form0044
Breakpoint cluster region protein0056
Serine/threonine-protein kinase pim-10044
Fibroblast growth factor receptor 10044
DNA topoisomerase 2-alpha01511
Cyclin-dependent kinase 40044
ADP/ATP translocase 30044
Inosine-5'-monophosphate dehydrogenase 20044
Proto-oncogene tyrosine-protein kinase Src0044
cAMP-dependent protein kinase type II-alpha regulatory subunit0044
Serine/threonine-protein kinase B-raf0258
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0044
Ribosyldihydronicotinamide dehydrogenase [quinone]0044
Tyrosine-protein kinase Fer0044
Protein kinase C alpha type0044
cAMP-dependent protein kinase catalytic subunit alpha0044
General transcription and DNA repair factor IIH helicase subunit XPD0044
Casein kinase II subunit alpha'0044
Ras-related protein Rab-6A0044
Ephrin type-A receptor 10044
Multifunctional protein ADE20044
cAMP-dependent protein kinase catalytic subunit gamma0033
cAMP-dependent protein kinase catalytic subunit beta0044
Ferrochelatase, mitochondrial0044
Ribosomal protein S6 kinase beta-10033
Tyrosine-protein kinase JAK10044
Cyclin-dependent kinase 20055
Beta-adrenergic receptor kinase 10044
Probable ATP-dependent RNA helicase DDX60044
Mitogen-activated protein kinase 3 0044
MAP/microtubule affinity-regulating kinase 30044
Mitogen-activated protein kinase 10145
Ephrin type-A receptor 20044
Ephrin type-B receptor 20044
Non-receptor tyrosine-protein kinase TYK20044
UMP-CMP kinase 0033
Phosphatidylethanolamine-binding protein 10044
Wee1-like protein kinase0044
Heme oxygenase 20044
S-adenosylmethionine synthase isoform type-20044
DnaJ homolog subfamily A member 10044
RAC-alpha serine/threonine-protein kinase0044
RAC-beta serine/threonine-protein kinase0044
Dual specificity protein kinase TTK0033
DNA replication licensing factor MCM40044
Myosin-100033
Dual specificity mitogen-activated protein kinase kinase 20347
Receptor-type tyrosine-protein kinase FLT30044
Bone morphogenetic protein receptor type-1A0044
Activin receptor type-1B0044
TGF-beta receptor type-10145
Serine/threonine-protein kinase receptor R30033
TGF-beta receptor type-20044
Electron transfer flavoprotein subunit beta0044
Tyrosine-protein kinase CSK0044
Glycine--tRNA ligase0044
Protein kinase C iota type0044
Exosome RNA helicase MTR40044
Tyrosine-protein kinase Tec0044
Tyrosine-protein kinase ABL20044
Tyrosine-protein kinase FRK0044
Tyrosine-protein kinase SYK0044
26S proteasome regulatory subunit 6B0044
Mitogen-activated protein kinase 80044
Mitogen-activated protein kinase 90044
Dual specificity mitogen-activated protein kinase kinase 40033
Dual specificity mitogen-activated protein kinase kinase 30044
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0044
Casein kinase I isoform alpha0044
Casein kinase I isoform delta0044
MAP kinase-activated protein kinase 20044
Elongation factor Tu, mitochondrial0044
Choline-phosphate cytidylyltransferase A0044
Cysteine--tRNA ligase, cytoplasmic0044
Casein kinase I isoform epsilon0044
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0044
Dual specificity protein kinase CLK10044
Dual specificity protein kinase CLK20044
Dual specificity protein kinase CLK30033
Glycogen synthase kinase-3 alpha0044
Glycogen synthase kinase-3 beta0044
Cyclin-dependent kinase 70044
Cyclin-dependent kinase 90044
Ras-related protein Rab-27A0044
Interleukin-1 receptor-associated kinase 10044
Ribosomal protein S6 kinase alpha-30044
Serine/threonine-protein kinase Nek20044
Serine/threonine-protein kinase Nek30044
Dual specificity mitogen-activated protein kinase kinase 60044
Serine/threonine-protein kinase PLK10044
LIM domain kinase 10044
LIM domain kinase 20044
Mitogen-activated protein kinase 100044
Tyrosine--tRNA ligase, cytoplasmic0044
5'-AMP-activated protein kinase subunit gamma-10044
Ephrin type-B receptor 30044
Ephrin type-A receptor 50044
Ephrin type-B receptor 40044
Ephrin type-A receptor 40044
Adenylate kinase 2, mitochondrial0044
Adenosine kinase0033
Ras-related protein Rab-100044
Actin-related protein 30145
Actin-related protein 20033
GTP-binding nuclear protein Ran0044
Casein kinase I isoform gamma-20044
Cyclin-dependent kinase 30022
Cyclin-dependent kinase 60044
Cyclin-dependent-like kinase 5 0044
Cyclin-dependent kinase 160044
Cyclin-dependent kinase 170044
Heat shock factor protein 10101
ATP-dependent 6-phosphofructokinase, platelet type0044
Dual specificity mitogen-activated protein kinase kinase 10347
DNA topoisomerase 2-beta01512
Protein kinase C theta type0044
Activin receptor type-10044
Macrophage-stimulating protein receptor0044
Focal adhesion kinase 10044
Protein kinase C zeta type0033
Protein kinase C delta type0044
Tyrosine-protein kinase BTK0044
Activated CDC42 kinase 10044
Epithelial discoidin domain-containing receptor 10044
Mitogen-activated protein kinase kinase kinase kinase 20044
Tyrosine-protein kinase Mer0022
Serine/threonine-protein kinase 40044
5'-AMP-activated protein kinase catalytic subunit alpha-10044
Dual specificity mitogen-activated protein kinase kinase 50044
Mitogen-activated protein kinase 70044
Serine/threonine-protein kinase PAK 20044
Serine/threonine-protein kinase 30044
Mitogen-activated protein kinase kinase kinase 10044
Integrin-linked protein kinase0044
Rho-associated protein kinase 10044
Non-receptor tyrosine-protein kinase TNK10044
Receptor-interacting serine/threonine-protein kinase 10101
Calcium/calmodulin-dependent protein kinase type II subunit gamma0044
Calcium/calmodulin-dependent protein kinase type II subunit delta0044
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0044
Activin receptor type-2B0044
Bone morphogenetic protein receptor type-20044
Protein-tyrosine kinase 60044
cGMP-dependent protein kinase 1 0044
Cyclin-dependent kinase 130044
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0044
Protein-tyrosine kinase 2-beta0044
Maternal embryonic leucine zipper kinase0044
Structural maintenance of chromosomes protein 1A0044
Chromodomain-helicase-DNA-binding protein 40044
Peroxisomal acyl-coenzyme A oxidase 10044
Cyclin-dependent kinase 100022
Ephrin type-A receptor 70033
Delta(24)-sterol reductase0044
Ribosomal protein S6 kinase alpha-10044
Dual specificity testis-specific protein kinase 10044
Myosin light chain kinase, smooth muscle0044
Mitogen-activated protein kinase 110044
Serine/threonine-protein kinase STK110044
Serine/threonine-protein kinase N10044
Serine/threonine-protein kinase N20044
Mitogen-activated protein kinase 140145
Calcium/calmodulin-dependent protein kinase type IV0044
Mitogen-activated protein kinase kinase kinase 110044
MAP kinase-activated protein kinase 30033
Discoidin domain-containing receptor 20044
AP2-associated protein kinase 10044
Myosin light chain kinase 30044
Uncharacterized aarF domain-containing protein kinase 50033
Putative heat shock protein HSP 90-beta 20044
Rab-like protein 30033
Serine/threonine-protein kinase MRCK alpha0044
Serine/threonine-protein kinase MRCK gamma0033
Acyl-CoA dehydrogenase family member 100044
Serine/threonine-protein kinase N30044
Serine/threonine-protein kinase ULK30044
Dual serine/threonine and tyrosine protein kinase0101
Uncharacterized protein FLJ452520044
Acyl-CoA dehydrogenase family member 110044
Serine/threonine-protein kinase/endoribonuclease IRE20044
Serine/threonine-protein kinase MARK20044
ATP-dependent RNA helicase DHX300044
Serine/threonine-protein kinase TAO10044
STE20-related kinase adapter protein alpha0044
Myosin-140044
AarF domain-containing protein kinase 10044
ATP-dependent RNA helicase DDX420033
Mitogen-activated protein kinase kinase kinase kinase 30044
MAP kinase-activated protein kinase 50044
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0022
Misshapen-like kinase 10044
Atypical kinase COQ8A, mitochondrial0044
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0044
Mitogen-activated protein kinase 150044
Serine/threonine-protein kinase Nek90044
ATP-dependent RNA helicase DDX10044
Mitogen-activated protein kinase kinase kinase kinase 10044
Aurora kinase B0044
MAP/microtubule affinity-regulating kinase 40044
Serine/threonine-protein kinase Nek10044
PAS domain-containing serine/threonine-protein kinase0033
Calcium/calmodulin-dependent protein kinase kinase 20044
EKC/KEOPS complex subunit TP53RK0044
Dual specificity testis-specific protein kinase 20044
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0044
Mitogen-activated protein kinase kinase kinase 50044
Mitogen-activated protein kinase kinase kinase 30044
Eukaryotic translation initiation factor 2-alpha kinase 10044
Nucleolar GTP-binding protein 10044
Serine/threonine-protein kinase D20044
NUAK family SNF1-like kinase 20022
RNA cytidine acetyltransferase0044
Serine/threonine-protein kinase SIK20044
STE20-like serine/threonine-protein kinase 0044
Serine/threonine-protein kinase TAO30044
dCTP pyrophosphatase 10044
Dual specificity protein kinase CLK40044
Casein kinase I isoform gamma-10044
Serine/threonine-protein kinase PAK 60033
Phenylalanine--tRNA ligase beta subunit0044
Isoleucine--tRNA ligase, mitochondrial0033
BMP-2-inducible protein kinase0044
Obg-like ATPase 10033
Midasin0044
Interleukin-1 receptor-associated kinase 40044
Mitogen-activated protein kinase kinase kinase 200044
Cyclin-dependent kinase 120044
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130033
Serine/threonine-protein kinase pim-20022
Serine/threonine-protein kinase 260044
Serine/threonine-protein kinase NLK0044
5'-AMP-activated protein kinase subunit gamma-20044
Serine/threonine-protein kinase TBK10044
Septin-90044
Ribosomal protein S6 kinase alpha-60044
TRAF2 and NCK-interacting protein kinase0044
Serine/threonine-protein kinase TAO20044
Serine/threonine-protein kinase ICK0044
RAC-gamma serine/threonine-protein kinase0044
Serine/threonine-protein kinase SIK30044
Mitogen-activated protein kinase kinase kinase 20044
Thyroid hormone receptor-associated protein 30044
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0033
Mitogen-activated protein kinase kinase kinase kinase 50044
Receptor-interacting serine/threonine-protein kinase 30145
Serine/threonine-protein kinase MRCK beta0044
Interleukin-1 receptor-associated kinase 30044
Serine/threonine-protein kinase 240044
Casein kinase I isoform gamma-30044
Mitogen-activated protein kinase kinase kinase 40044
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
cytochrome P450 2C9 precursor1001
Myeloperoxidase0101
Dihydrofolate reductase0303
Histamine H2 receptor2002
5-hydroxytryptamine receptor 60101
histone deacetylase 9 isoform 31001
lethal factor (plasmid)1001
Prothrombin0001
Regulatory protein E20011
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB10517
DNA topoisomerase 10102
Polyunsaturated fatty acid lipoxygenase ALOX150202
DNA topoisomerase 20001
ATP-dependent translocase ABCB10202
UDP-glucuronosyltransferase 1A1 0203
Serum paraoxonase/arylesterase 10101
Glutamate receptor ionotropic, NMDA 1 0001
Caspase-30101
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
DNA topoisomerase 2-alpha 0001
Glutamate receptor ionotropic, NMDA 2D0001
Tubulin beta-2B chain0101
Integrase 0101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
Glutamate receptor ionotropic, NMDA 3B0001
Solute carrier organic anion transporter family member 1B30203
Glutamate receptor ionotropic, NMDA 3A0001
potassium voltage-gated channel subfamily H member 2 isoform d3003
D(2) dopamine receptor0101
Amine oxidase [flavin-containing] A0101
D(4) dopamine receptor0101
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0202
Delta-type opioid receptor0303
Mu-type opioid receptor0314
Kappa-type opioid receptor0202
Histamine H1 receptor0101
Mu-type opioid receptor0213
D(3) dopamine receptor0101
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Potassium voltage-gated channel subfamily H member 20202
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10101
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Thrombopoietin1001
nonstructural protein 13003
Vpr2002
Solute carrier family 22 member 80002
Amyloid-beta precursor protein1001
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Ras-related C3 botulinum toxin substrate 10011
Serine/threonine-protein kinase ATR0011
Serine/threonine-protein kinase Nek70011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0033
Long-chain-fatty-acid--CoA ligase 50011
Serine/threonine-protein kinase 38-like0011
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
DNA repair protein RAD52 homolog isoform a0001
Cytochrome P450 2C80001
Mast/stem cell growth factor receptor Kit0112
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50001
cytochrome P450 2D66006
DNA polymerase beta2002
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
7,8-dihydro-8-oxoguanine triphosphatase0101
Toll-like receptor 80011
Toll-like receptor 70011
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
Chain A, Cruzipain1001
Parkin1001
Ornithine decarboxylase0001
Retinoic acid receptor alpha0101
Alpha-1B adrenergic receptor0202
Alpha-2B adrenergic receptor0202
Retinoic acid receptor gamma0101
Retinoic acid receptor beta0101
Cellular retinoic acid-binding protein 20011
Cellular retinoic acid-binding protein 10101
5-hydroxytryptamine receptor 2B0404
Alpha-1A adrenergic receptor0202
Cellular retinoic acid-binding protein 10011
Olfactory receptor 51E20101
Chymotrypsinogen A0101
GALC protein2002
cytochrome P450 2D6 isoform 11001
cytochrome P450 2C19 precursor2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
importin subunit beta-1 isoform 13003
snurportin-13003
GTP-binding nuclear protein Ran isoform 11001
Cytochrome P450 1A10202
Cytochrome P450 1B10101
Cereblon isoform 40303
Bromodomain-containing protein 40101
DNA-binding protein Ikaros0014
DNA damage-binding protein 10213
Protein cereblon0429
Zinc finger protein Aiolos0011
15-lipoxygenase, partial3003
glucocerebrosidase1001
Large neutral amino acids transporter small subunit 1 0101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, 2-oxoglutarate Oxygenase4004
apical membrane antigen 1, AMA12002
transcriptional regulator ERG isoform 32002
UDP-glucose 6-dehydrogenase0101
Hypoxanthine-guanine phosphoribosyltransferase0001
UDP-glucose 6-dehydrogenase0101
Prostaglandin G/H synthase 10202
UDP-glucuronosyltransferase 1A1 0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
DNA polymerase kappa isoform 12002
caspase-1 isoform alpha precursor1001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Carbonic anhydrase 20112
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30002
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Androgen receptor0303
Nuclear receptor subfamily 1 group I member 20011
Translocator protein0101
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
UDP-glucuronosyltransferase 1A40101
UDP-glucuronosyltransferase 2B10 0101
STE240001
CAAX prenyl protease0001
streptokinase A precursor0011
Trypsin0001
Albumin0011
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA gyrase subunit B0102
DNA gyrase subunit A0102
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Glutamine synthetase0011
Histamine H1 receptor0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Estrogen receptor beta0202
heat shock protein HSP 90-alpha isoform 20001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
D(1A) dopamine receptor1001
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
5-hydroxytryptamine receptor 40202
Carbonic anhydrase 10101
Aldo-keto reductase family 1 member B10202
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium-dependent noradrenaline transporter 0202
Sodium- and chloride-dependent GABA transporter 10101
5-hydroxytryptamine receptor 2C0202
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit alpha-50011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit beta-20011
Sodium- and chloride-dependent betaine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-40011
Fatty-acid amide hydrolase 10101
Gamma-aminobutyric acid receptor subunit alpha-60011
UDP-glucuronosyltransferase 1A80001
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Alpha-synuclein1001
Serine/threonine-protein kinase mTOR0112
G protein-coupled receptor kinase 60022
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Cyclin-dependent kinase 180022
Peptidyl-prolyl cis-trans isomerase FKBP50101
Programmed cell death protein 40011
Regulatory-associated protein of mTOR0101
Calcium/calmodulin-dependent protein kinase type 1G0011
Target of rapamycin complex subunit LST80101
Serine/threonine-protein kinase mTOR 0101
Solute carrier organic anion transporter family member 1B10102
Prostaglandin G/H synthase 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Prostaglandin G/H synthase 20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Peroxisome proliferator-activated receptor gamma0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
NFKB1 protein, partial1001
procathepsin L isoform 1 preproprotein0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]