UTP binding

Definition

Target type: molecularfunction

Binding to UTP, uridine 5'-triphosphate. [GOC:hjd, ISBN:0198506732]

UTP binding is a molecular function that involves the specific recognition and interaction of a protein or other molecule with the nucleotide uridine triphosphate (UTP). UTP plays a crucial role in various cellular processes, including:

- **Nucleic acid synthesis:** UTP is a precursor for RNA synthesis, where it is incorporated into the growing RNA chain by RNA polymerase.
- **Glycogen synthesis:** UTP is involved in the synthesis of glycogen, a storage form of glucose in animals, by providing the activated sugar uridine diphosphate glucose (UDP-glucose).
- **Signal transduction:** UTP can act as a signaling molecule, binding to specific receptors on cell surfaces and triggering downstream signaling pathways.
- **Metabolic regulation:** UTP can regulate the activity of enzymes involved in various metabolic pathways.

The binding of UTP to a protein or molecule typically occurs through specific interactions between the nucleotide's phosphate groups, ribose sugar, and the uracil base with amino acid residues in the binding site. These interactions can be mediated by hydrogen bonds, electrostatic interactions, and hydrophobic forces.

The specific molecular function of UTP binding can vary depending on the protein or molecule involved and its cellular context. For example, some proteins may specifically bind UTP to utilize it as a substrate for enzymatic reactions, while others may bind UTP to regulate their activity or to act as signaling molecules.

In summary, UTP binding is a fundamental molecular function that is essential for a wide range of cellular processes, including nucleic acid synthesis, glycogen metabolism, signal transduction, and metabolic regulation.'
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Proteins (1)

Compounds (60)