| Assay ID | Title | Year | Journal | Article |
|---|
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID702181 | Displacement of [3H]R-PIA from human A1 adenosine receptor expressed in CHO cells after 60 min by Perkin Elmer Liquid Scintillation Analyzer | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID33752 | Ratio of A2 to A1. | 1992 | Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
| Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. |
| AID30329 | Inhibition of [125I]APNEA binding to adenosine A1 receptor of rat brain | 1989 | Journal of medicinal chemistry, May, Volume: 32, Issue:5
| Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptors. |
| AID32502 | Inhibition of binding of 1 nM N6-[3H]cyclohexyladenosine to adenosine A1 receptor on rat cerebral cortical membranes. | 1985 | Journal of medicinal chemistry, Sep, Volume: 28, Issue:9
| Functionalized congeners of adenosine: preparation of analogues with high affinity for A1-adenosine receptors. |
| AID702166 | Anticonvulsant activity in CF-1 albino mouse assessed as protection against subcutaneous metrazol-induced seizures at 1 mg/kg, ip | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID702179 | Displacement of [3H]CGS21680 from human A2a adenosine receptor expressed in HEK293 cells after 60 min by Perkin Elmer Liquid Scintillation Analyzer | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID702177 | Displacement of [125I]I-AB-MECA from human A3 adenosine receptor expressed in CHO cells after 60 min Packard Cobra 2 gamma-counter | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID31850 | Inhibition of [3H]PIA binding to rat cortical adenosine A1 receptor | 1992 | Journal of medicinal chemistry, Oct-30, Volume: 35, Issue:22
| Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists. |
| AID702171 | Anticonvulsant activity in ip dosed CF-1 albino mouse assessed as protection against 6 Hz psychomotor seizure after 1 hr by minimal clonic seizure test | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID31848 | Affinity for adenosine A1 receptor using [3H]N6-(phenylisopropyl)adenosine (R)-[3H]-PIA as a radioligand in rat brain. | 1989 | Journal of medicinal chemistry, May, Volume: 32, Issue:5
| Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptors. |
| AID702168 | Anticonvulsant activity in CF-1 albino mouse assessed as protection against maximal electroshock-induced seizures at 2 mg/kg, ip by MES test | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID32177 | Binding affinity against adenosine A1 receptor using [3H]-CHA or [3H]PIA as radioligand | 1992 | Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
| Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. |
| AID31977 | Displacement of [3H]-N6 -(phenylisopropyl)-adenosine (R)-[3H]-PIA from Adenosine A1 receptor of calf brain | 1989 | Journal of medicinal chemistry, May, Volume: 32, Issue:5
| Electrophilic derivatives of purines as irreversible inhibitors of A1 adenosine receptors. |
| AID702176 | Activity at human A1 adenosine receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production at 10 uM after 30 min | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID702169 | Anticonvulsant activity in CF-1 albino mouse assessed as protection against maximal electroshock-induced seizures at 1 mg/kg, ip by MES test | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID702173 | Toxicity in ip dosed CF-1 albino mouse assessed as behavioral changes after 4 hrs by rotarod test | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID179751 | In vitro inhibition of synaptic potential in the hippocampal formation (synaptic responses (fEPSPs) recorded in the CAI region of in vivo hippocampal slices in rat brain) | 1992 | Journal of medicinal chemistry, Oct-30, Volume: 35, Issue:22
| Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists. |
| AID33746 | Binding affinity against adenosine A2 receptor using [3H]- NECA as radioligand | 1992 | Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
| Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. |
| AID702167 | Anticonvulsant activity in CF-1 albino mouse assessed as protection against subcutaneous metrazol-induced seizures at 3 mg/kg, ip | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID702170 | Anticonvulsant activity in CF-1 albino mouse assessed as protection against maximal electroshock-induced seizures at 3 mg/kg, ip by MES test | 2012 | Journal of medicinal chemistry, Sep-27, Volume: 55, Issue:18
| Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |