8-azanebularine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 10106291 |
| CHEMBL ID | 1651380 |
| MeSH ID | M0510331 |
| Synonym |
|---|
| bdbm50335313 |
| 8-aza-nebularine |
| CHEMBL1651380 , |
| 8-azanebularine |
| HY-145442 |
| CS-0374337 |
| (2r,3s,4r,5r)-2-(hydroxymethyl)-5-{3h-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl}oxolane-3,4-diol |
| 38874-46-3 |
| (2r,3s,4r,5r)-2-(hydroxymethyl)-5-(triazolo[4,5-d]pyrimidin-3-yl)tetrahydrofuran-3,4-diol |
| EX-A7845Y |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Adenosine deaminase | Homo sapiens (human) | Ki | 0.0400 | 0.0000 | 0.3088 | 7.0000 | AID554264 |
| Adenosine deaminase | Bos taurus (cattle) | Ki | 0.0400 | 0.0000 | 0.4893 | 7.0000 | AID554263 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| adenosine deaminase activity | Adenosine deaminase | Homo sapiens (human) |
| protein binding | Adenosine deaminase | Homo sapiens (human) |
| zinc ion binding | Adenosine deaminase | Homo sapiens (human) |
| deaminase activity | Adenosine deaminase | Homo sapiens (human) |
| 2'-deoxyadenosine deaminase activity | Adenosine deaminase | Homo sapiens (human) |
| adenosine deaminase activity | Adenosine deaminase | Bos taurus (cattle) |
| protein binding | Adenosine deaminase | Bos taurus (cattle) |
| zinc ion binding | Adenosine deaminase | Bos taurus (cattle) |
| 2'-deoxyadenosine deaminase activity | Adenosine deaminase | Bos taurus (cattle) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Process | via Protein(s) | Taxonomy |
|---|---|---|
| lysosome | Adenosine deaminase | Homo sapiens (human) |
| cytosol | Adenosine deaminase | Homo sapiens (human) |
| plasma membrane | Adenosine deaminase | Homo sapiens (human) |
| external side of plasma membrane | Adenosine deaminase | Homo sapiens (human) |
| cell surface | Adenosine deaminase | Homo sapiens (human) |
| membrane | Adenosine deaminase | Homo sapiens (human) |
| cytoplasmic vesicle lumen | Adenosine deaminase | Homo sapiens (human) |
| anchoring junction | Adenosine deaminase | Homo sapiens (human) |
| cytosol | Adenosine deaminase | Homo sapiens (human) |
| external side of plasma membrane | Adenosine deaminase | Homo sapiens (human) |
| lysosome | Adenosine deaminase | Bos taurus (cattle) |
| cytoplasmic vesicle lumen | Adenosine deaminase | Bos taurus (cattle) |
| anchoring junction | Adenosine deaminase | Bos taurus (cattle) |
| [Information is prepared from geneontology information from the June-17-2024 release] | ||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID554263 | Inhibition of calf intestine adenosine deaminase by Lineweaver-Burk plot analysis | 2011 | Journal of medicinal chemistry, Jan-13, Volume: 54, Issue:1 | Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors. |
| AID554264 | Inhibition of adenosine deaminase | 2011 | Journal of medicinal chemistry, Jan-13, Volume: 54, Issue:1 | Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (22.47) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||