| Assay ID | Title | Year | Journal | Article |
|---|
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID34582 | Concentration required to increase Adenosine A2A receptor mediated P12 Adenylate cyclase activity | 1991 | Journal of medicinal chemistry, Dec, Volume: 34, Issue:12
| Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. |
| AID34265 | Effect on forskolin-stimulated cyclic AMP production in intact chinese hamster ovary (CHO) cell expressing the human Adenosine A3 receptor | 2002 | Journal of medicinal chemistry, Sep-26, Volume: 45, Issue:20
| Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. |
| AID235520 | Selectivity, ratio of affinity towards adenosine A2A to A1 | 2000 | Journal of medicinal chemistry, Jul-27, Volume: 43, Issue:15
| A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives. |
| AID32206 | Displacement of [3H]CHA from adenosine A1 receptor of rat whole brain | 1985 | Journal of medicinal chemistry, Oct, Volume: 28, Issue:10
| N6-cycloalkyladenosines. Potent, A1-selective adenosine agonists. |
| AID42825 | Antagonist binding of N6-cyclohexyl-[3H]-adenosine to bovine brain | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID32361 | Evaluated for the binding affinity towards the Adenosine A1 receptor in corpora striata of rats using [3H]CHA as radioligand. | 1990 | Journal of medicinal chemistry, Aug, Volume: 33, Issue:8
| 4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants. |
| AID233378 | Inhibitory selectivity at Adenosine A3 receptor compared to Adenosine 1 receptor. | 1998 | Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
| 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. |
| AID34574 | Affinity for human Adenosine A3 receptor expressed in CHO cell | 2002 | Journal of medicinal chemistry, Sep-26, Volume: 45, Issue:20
| Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. |
| AID33590 | Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membrane | 1985 | Journal of medicinal chemistry, Oct, Volume: 28, Issue:10
| N6-cycloalkyladenosines. Potent, A1-selective adenosine agonists. |
| AID196738 | Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat fat | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID229446 | Relative binding to A2 and A1 receptors (ratio of Ki) | 1985 | Journal of medicinal chemistry, Oct, Volume: 28, Issue:10
| N6-cycloalkyladenosines. Potent, A1-selective adenosine agonists. |
| AID195543 | Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat brain | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID30353 | Affinity constant for inhibition of A1 receptor control of adenylate cyclase in adipocytes, heart and brain cells | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID195542 | Antagonist binding of 2-chloro-[3H]-adenosine to rat brain | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID196931 | Antagonist binding of N6-cyclohexyl-[3H]-adenosine to rat testes | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID33019 | Selectivity for Adenosine A2A over Adenosine A1 receptor | 2002 | Journal of medicinal chemistry, Mar-14, Volume: 45, Issue:6
| Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues. |
| AID31976 | Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranes | 2000 | Journal of medicinal chemistry, Jul-27, Volume: 43, Issue:15
| A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives. |
| AID228918 | Molar potency ratio was evaluated | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Dog coronary artery adenosine receptor: structure of the N6-alkyl subregion. |
| AID33567 | Binding affinity to A2 adenosine receptor in rat striatal membranes by [3H]NECA (1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide) displacement. | 1987 | Journal of medicinal chemistry, Oct, Volume: 30, Issue:10
| N6-(2,2-diphenylethyl)adenosine, a novel adenosine receptor agonist with antipsychotic-like activity. |
| AID32360 | Binding affinity for Adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]-CHA | 1990 | Journal of medicinal chemistry, Aug, Volume: 33, Issue:8
| 4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants. |
| AID233379 | Inhibitory selectivity at Adenosine A3 receptor compared to Adenosine 2A receptor. | 1998 | Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
| 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. |
| AID34117 | Ability to displace the specific binding of [3H](R)-PIA to adenosine A3 receptor from rat testis membranes | 2000 | Journal of medicinal chemistry, Jul-27, Volume: 43, Issue:15
| A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives. |
| AID33018 | Ratio of binding potencies at Adenosine A2A receptor and Adenosine A1A receptor | 1991 | Journal of medicinal chemistry, Dec, Volume: 34, Issue:12
| Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. |
| AID233377 | Inhibitory selectivity at Adenosine 2A receptor compared to Adenosine 1 receptor. | 1998 | Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
| 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. |
| AID33333 | Affinity to Adenosine A3 receptor of rat testis membrane using [3H](R)-PIA with 150 nM DPCPX | 2002 | Journal of medicinal chemistry, Mar-14, Volume: 45, Issue:6
| Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues. |
| AID131363 | Effect on Motor activity in mouse following i.p. administration. | 1987 | Journal of medicinal chemistry, Oct, Volume: 30, Issue:10
| N6-(2,2-diphenylethyl)adenosine, a novel adenosine receptor agonist with antipsychotic-like activity. |
| AID33022 | Ability to displace [3H]-CGS- 21680 from Adenosine A2A receptor of rat brain striatum at 10e-5 M | 2002 | Journal of medicinal chemistry, Mar-14, Volume: 45, Issue:6
| Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues. |
| AID235522 | Selectivity, ratio of affinity towards adenosine A3 to A2A | 2000 | Journal of medicinal chemistry, Jul-27, Volume: 43, Issue:15
| A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives. |
| AID33726 | Binding affinity for Adenosine A2 receptor in corpora striata of rats using [3H]NECA | 1990 | Journal of medicinal chemistry, Aug, Volume: 33, Issue:8
| 4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants. |
| AID131362 | Effect on Ataxia in mouse following i.p. administration. | 1987 | Journal of medicinal chemistry, Oct, Volume: 30, Issue:10
| N6-(2,2-diphenylethyl)adenosine, a novel adenosine receptor agonist with antipsychotic-like activity. |
| AID31412 | Evaluated for the binding affinity towards the Adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand. | 1990 | Journal of medicinal chemistry, Aug, Volume: 33, Issue:8
| 4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants. |
| AID32872 | Inhibition of [3H]- NECA binding to adenosine receptor A2A | 1991 | Journal of medicinal chemistry, Dec, Volume: 34, Issue:12
| Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. |
| AID235521 | Selectivity, ratio of affinity towards adenosine A3 to A1 | 2000 | Journal of medicinal chemistry, Jul-27, Volume: 43, Issue:15
| A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives. |
| AID33928 | Inhibitory activity at Adenosine A2A receptor by inhibition of [3H]-CGS- 21680 binding to bovine striatal membranes. | 1998 | Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
| 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. |
| AID34272 | Percent efficacy against human Adenosine A3 receptor expressed in CHO cell | 2002 | Journal of medicinal chemistry, Sep-26, Volume: 45, Issue:20
| Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. |
| AID34158 | Inhibition of adenyl cyclase via P site in adipocytes; Inactive | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID78489 | Antagonist binding of N6-cyclohexyl-[3H]-adenosine to guinea pig brain | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID32180 | Inhibition of [3H]- (R)-P1A binding to adenosine A1 receptor | 1991 | Journal of medicinal chemistry, Dec, Volume: 34, Issue:12
| Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. |
| AID32015 | Binding affinity to adenosine A1 receptor in rat whole brain membranes by [3H]N6-cyclohexyladenosine displacement. | 1987 | Journal of medicinal chemistry, Oct, Volume: 30, Issue:10
| N6-(2,2-diphenylethyl)adenosine, a novel adenosine receptor agonist with antipsychotic-like activity. |
| AID33909 | Affinity constant for A2 receptor control of adenylate cyclase in adipocytes, heart and brain cells | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID33482 | Inhibitory activity against Adenosine A3 receptor by inhibiting specific [3H](R)-PIA binding to rat testis membranes | 1998 | Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
| 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. |
| AID33490 | Selectivity for Adenosine A3 over Adenosine A1 receptor | 2002 | Journal of medicinal chemistry, Mar-14, Volume: 45, Issue:6
| Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues. |
| AID33917 | Ability to displace the specific binding of [3H]-CGS- to adenosine A2A receptor form bovine brain striatal membranes | 2000 | Journal of medicinal chemistry, Jul-27, Volume: 43, Issue:15
| A novel class of highly potent and selective A1 adenosine antagonists: structure-affinity profile of a series of 1,8-naphthyridine derivatives. |
| AID33491 | Selectivity towards Adenosine A3 receptor to Adenosine A2A receptor | 2002 | Journal of medicinal chemistry, Mar-14, Volume: 45, Issue:6
| Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues. |
| AID32002 | Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovine brain cortical membranes. | 1998 | Journal of medicinal chemistry, May-07, Volume: 41, Issue:10
| 2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. |
| AID195544 | Antagonist binding of N6-cyclohexyl-[3H]-adenosine to rat brain | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Adenosine receptors: targets for future drugs. |
| AID25507 | HPLC capacity factor (k') | 1985 | Journal of medicinal chemistry, Nov, Volume: 28, Issue:11
| Dog coronary artery adenosine receptor: structure of the N6-alkyl subregion. |
| AID31854 | Inhibition of [3H]CHA (N6-cyclohexyl adenosine) to rat brain membrane Adenosine A1 receptor | 2002 | Journal of medicinal chemistry, Mar-14, Volume: 45, Issue:6
| Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues. |
| AID1345618 | Human A2A receptor (Adenosine receptors) | 1998 | Naunyn-Schmiedeberg's archives of pharmacology, Jan, Volume: 357, Issue:1
| Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. |
| AID1345721 | Human A2B receptor (Adenosine receptors) | 2005 | Biochemical pharmacology, Nov-25, Volume: 70, Issue:11
| Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors. |
| AID1345618 | Human A2A receptor (Adenosine receptors) | 1997 | British journal of pharmacology, Jun, Volume: 121, Issue:3
| Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261. |
| AID1345685 | Human A1 receptor (Adenosine receptors) | 1994 | The Journal of biological chemistry, Jan-28, Volume: 269, Issue:4
| A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding. |
| AID1345822 | Human A3 receptor (Adenosine receptors) | 1998 | Naunyn-Schmiedeberg's archives of pharmacology, Jan, Volume: 357, Issue:1
| Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells. |
| AID1345822 | Human A3 receptor (Adenosine receptors) | 1993 | Proceedings of the National Academy of Sciences of the United States of America, Nov-01, Volume: 90, Issue:21
| Molecular cloning and characterization of the human A3 adenosine receptor. |
| AID1345721 | Human A2B receptor (Adenosine receptors) | 1999 | Molecular pharmacology, Oct, Volume: 56, Issue:4
| Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells. |
| AID1345685 | Human A1 receptor (Adenosine receptors) | 1994 | The Journal of biological chemistry, Dec-23, Volume: 269, Issue:51
| Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor. |
| AID1345822 | Human A3 receptor (Adenosine receptors) | 2000 | Molecular pharmacology, May, Volume: 57, Issue:5
| [(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |