| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID230534 | Ratio of selectivity for A3 and A1 receptors at rat brain | 1994 | Journal of medicinal chemistry, Sep-30, Volume: 37, Issue:20
| Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors. |
| AID33486 | Displacement of [125I]AB-MECA from membranes of CHO cells stably transfected with the rat adenosine A3 receptor cDNA | 1994 | Journal of medicinal chemistry, Sep-30, Volume: 37, Issue:20
| Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors. |
| AID32514 | Displacement of [3H]PIA from adenosine A1 receptors of rat brain membrane | 1994 | Journal of medicinal chemistry, Sep-30, Volume: 37, Issue:20
| Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors. |
| AID259521 | Binding affinity to rat adenosine A2A receptor | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor. |
| AID33176 | Binding affinity at human Adenosine A2B receptor expressed in HEK293 cells, using [125I]ABOPX as radioligand | 2002 | Journal of medicinal chemistry, May-23, Volume: 45, Issue:11
| Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions. |
| AID259511 | Binding affinity to recombinant human adenosine A2A receptor | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor. |
| AID32191 | Binding affinity towards adenosine A1 receptor in rat cerebral cortical membranes by [3H]cyclohexyladenosine displacement. | 1985 | Journal of medicinal chemistry, Sep, Volume: 28, Issue:9
| Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors. |
| AID33728 | Inhibition of binding of [3H]5'-(N-ethylcarbamoyl)-adenosine to adenosine A2 receptor in rat striatal membranes | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
| Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. |
| AID30622 | Binding affinity against A2 adenosine receptor in guinea pig cerebral cortical slices by [3H]-adenine displacement. | 1985 | Journal of medicinal chemistry, Sep, Volume: 28, Issue:9
| Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors. |
| AID30798 | Inhibition of NECA binding to adenosine A2 receptor mediates reduced adenylate cyclase activity in human platelets | 1988 | Journal of medicinal chemistry, Apr, Volume: 31, Issue:4
| 125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors. |
| AID32177 | Binding affinity against adenosine A1 receptor using [3H]-CHA or [3H]PIA as radioligand | 1992 | Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
| Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. |
| AID32500 | Inhibition of binding of 1 nM [3H]N-6-(phenylisopropyl)adenosine to adenosine A1 receptor in rat cortical membranes | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
| Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. |
| AID259510 | Binding affinity to recombinant human adenosine A2B receptor | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor. |
| AID259512 | Selectivity for human adenosine A2B over human adenosine A2A receptor | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor. |
| AID34250 | Antagonist activity against recombinant human adenosine A2A receptor expressed in HEK293 cells in presence of [125I]iodo-ZM-241385 radioligand. | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID234381 | Selectivity ratio of hA1 to hA2B | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID234382 | Selectivity ratio of hA2A to hA2B | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID30463 | Antagonist activity against recombinant human adenosine A1 receptor expressed in HEK293 cells in presence of [125I]IABA radioligand. | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID30639 | Antagonism of NECA-induced stimulation of adenylate cyclase activity in human platelet membranes at A2-adenosine receptor; value ranges from 1500-3900 | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1
| Xanthine functionalized congeners as potent ligands at A2-adenosine receptors. |
| AID230003 | Ratio of Ki for A1 and A2 receptors | 1985 | Journal of medicinal chemistry, Sep, Volume: 28, Issue:9
| Functionalized congeners of 1,3-dialkylxanthines: preparation of analogues with high affinity for adenosine receptors. |
| AID33752 | Ratio of A2 to A1. | 1992 | Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
| Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. |
| AID230229 | Inhibitory selectivity for A2 receptor in rat striatal membranes and A1 receptor in rat cortical membranes | 1989 | Journal of medicinal chemistry, Aug, Volume: 32, Issue:8
| Sulfur-containing 1,3-dialkylxanthine derivatives as selective antagonists at A1-adenosine receptors. |
| AID32495 | Inhibition of [3H]- PIA binding at adenosine A1 receptor on rat cerebral cortex membranes. | 1987 | Journal of medicinal chemistry, Jan, Volume: 30, Issue:1
| Xanthine functionalized congeners as potent ligands at A2-adenosine receptors. |
| AID33940 | Displacement of [3H]-CGS- 21680 from adenosine A2a receptors of rat striatal membrane | 1994 | Journal of medicinal chemistry, Sep-30, Volume: 37, Issue:20
| Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors. |
| AID33354 | Antagonist activity against rat adenosine A3 receptor using [125I]I-AB-MECA or [125 I]IABA | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID34864 | Antagonist activity against human adenosine A3 receptor expressed in HEK cells in presence of [125]IAB-MECA or [125I]IABA radioligand. | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID259517 | Binding affinity to recombinant human adenosine A3 receptor | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor. |
| AID32886 | Antagonist activity against adenosine A2A receptor in rat striatal membrane in presence of [3H]CGS-21680 radioligand. | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID259522 | Binding affinity to rat adenosine A1 receptor | 2006 | Journal of medicinal chemistry, Jan-12, Volume: 49, Issue:1
| Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor. |
| AID31846 | Binding affinity for adenosine A1 receptor as inhibition of [125-I]-labeled aminobenzyl adenosine binding to bovine brain membranes | 1988 | Journal of medicinal chemistry, Apr, Volume: 31, Issue:4
| 125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors. |
| AID32335 | Antagonist activity against adenosine A1 receptor in rat brain membrane in presence of [3H]R-PIA radioligand. | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID230535 | Ratio of selectivity for A3 and A2a receptors at rat brain | 1994 | Journal of medicinal chemistry, Sep-30, Volume: 37, Issue:20
| Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors. |
| AID234383 | Selectivity ratio of hA3 to hA2B | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID7693 | Antagonist activity against human A2B adenosine receptor expressed in HEK293 cells uisng [3H]ZM-241385 or [125I]-IABOPX | 2000 | Journal of medicinal chemistry, Mar-23, Volume: 43, Issue:6
| Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors. |
| AID33746 | Binding affinity against adenosine A2 receptor using [3H]- NECA as radioligand | 1992 | Journal of medicinal chemistry, Feb-07, Volume: 35, Issue:3
| Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. |
| AID1345721 | Human A2B receptor (Adenosine receptors) | 2001 | Biochemical pharmacology, Mar-15, Volume: 61, Issue:6
| [3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |