| Assay ID | Title | Year | Journal | Article |
|---|
| AID649020 | Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in HEK293 cells after 120 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID325512 | Displacement of [3H]ZM-241385 from human adenosine A2A receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry, Mar-01, Volume: 16, Issue:5
| 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists. |
| AID33177 | Binding affinity of compound for displacement of [3H]DPCPX binding in HEK293 membranes expressing human A2B adenosine receptors | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID372140 | Binding affinity to human adenosine A3 receptor | 2009 | Journal of medicinal chemistry, Jul-09, Volume: 52, Issue:13
| 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity. |
| AID254330 | Antagonist activity against human Adenosine A2b receptor | 2005 | Journal of medicinal chemistry, Nov-03, Volume: 48, Issue:22
| Molecular modeling and molecular dynamics simulation of the human A2B adenosine receptor. The study of the possible binding modes of the A2B receptor antagonists. |
| AID372137 | Binding affinity to human adenosine A1 receptor | 2009 | Journal of medicinal chemistry, Jul-09, Volume: 52, Issue:13
| 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity. |
| AID233613 | Ratio of binding affinities for adenosine A1 and adenosine A2b receptors | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13
| A mild, efficient and alpha-selective glycosidation by using potassium dodecatungstocobaltate trihydrate as catalyst. |
| AID33172 | Inhibitory activity against cAMP production in CHO cells transfected with human A2B adenosine receptor | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID649019 | Displacement of [3H]ZM241385 from human recombinant adenosine A2A receptor expressed in CHO cells after 120 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID33949 | Maximum binding [3H]-MRE 2029-F20 towards human adenosine A2b receptor expressed in CHO cells | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13
| A mild, efficient and alpha-selective glycosidation by using potassium dodecatungstocobaltate trihydrate as catalyst. |
| AID30459 | Binding affinity towards human adenosine A1 receptor expressed in CHO cells using [3H]DPCPX | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13
| A mild, efficient and alpha-selective glycosidation by using potassium dodecatungstocobaltate trihydrate as catalyst. |
| AID1289961 | Displacement of [3H] DPCPX from human recombinant Adenosine A2B receptor expressed in HEK293 cells after 60 mins | 2016 | Journal of medicinal chemistry, Mar-10, Volume: 59, Issue:5
| Discovery of Potent and Highly Selective A2B Adenosine Receptor Antagonist Chemotypes. |
| AID34240 | Binding affinity of compound for displacement of specific [3H]ZM-241385 binding at human adenosine A2A receptor expressed in CHO cells | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID494495 | Antagonist activity against human adenosine A2B receptor | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8
| Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods. |
| AID372139 | Binding affinity to human adenosine A2B receptor | 2009 | Journal of medicinal chemistry, Jul-09, Volume: 52, Issue:13
| 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity. |
| AID33952 | Binding affinity of [3H]-MRE 2029-F20 towards human adenosine A2b receptor expressed in CHO cells | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13
| A mild, efficient and alpha-selective glycosidation by using potassium dodecatungstocobaltate trihydrate as catalyst. |
| AID649018 | Displacement of [3H]DPCPX from human recombinant adenosine A1 receptor expressed in CHO cells after 120 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID494498 | Antagonist activity against human adenosine A3 receptor | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8
| Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods. |
| AID325511 | Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry, Mar-01, Volume: 16, Issue:5
| 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists. |
| AID231499 | Ratio of binding affinity of human A3 receptor to human A2B receptor expressed in CHO cells | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID231498 | Ratio of binding affinity of human A2A receptor to human A2B receptor expressed in CHO cells | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID34707 | Binding affinity of compound for displacement of specific [3H]MRE3008-F20 binding at human A3 receptors expressed in CHO cells | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID649023 | Antagonist activity at human recombinant adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced [3H]cAMP production after 150 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID494496 | Antagonist activity against human adenosine A2A receptor | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8
| Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods. |
| AID372138 | Binding affinity to human adenosine A2A receptor | 2009 | Journal of medicinal chemistry, Jul-09, Volume: 52, Issue:13
| 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity. |
| AID30448 | Displacement of specific [3H]DPCPX binding at human adenosine A1 receptor expressed in CHO cells | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID34084 | Inhibition of [3H]-ZM 241385 binding to human adenosine A2a receptor expressed in CHO cells; Not significant | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13
| A mild, efficient and alpha-selective glycosidation by using potassium dodecatungstocobaltate trihydrate as catalyst. |
| AID372146 | Selectivity ratio of Ki for human adenosine A1 receptor to Ki for human adenosine A2B receptor | 2009 | Journal of medicinal chemistry, Jul-09, Volume: 52, Issue:13
| 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity. |
| AID34430 | Inhibition of [3H]-MRE 3008-F20 binding to human adenosine A3 receptor expressed in CHO cells; Not significant | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13
| A mild, efficient and alpha-selective glycosidation by using potassium dodecatungstocobaltate trihydrate as catalyst. |
| AID649033 | Displacement of [3H]MRE2029-F20 from human recombinant adenosine A2B receptor expressed in CHO cells | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID33178 | Binding affinity of compound for displacement of specific [3H]- DPCPX binding at human A2B receptors expressed in HEK293 cells | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID231497 | Ratio of binding affinity of human A1 receptor to human A2B receptor expressed in CHO cells | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID494497 | Antagonist activity against human adenosine A1 receptor | 2010 | European journal of medicinal chemistry, Aug, Volume: 45, Issue:8
| Insights into binding modes of adenosine A(2B) antagonists with ligand-based and receptor-based methods. |
| AID649021 | Displacement of [3H]MRE3008-F20 from human recombinant adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counting | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID1428100 | Displacement of [3H]DPCPX from human adenosine receptor A2b expressed in HEK293 cell membranes | 2017 | European journal of medicinal chemistry, Feb-15, Volume: 127 | A |
| AID1871328 | Antagonist activity at adenosine A2A receptor (unknown origin) | 2022 | European journal of medicinal chemistry, Jan-05, Volume: 227 | Adenosine receptor antagonists: Recent advances and therapeutic perspective. |
| AID649025 | Binding affinity to human adenosine A2A receptor | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID649027 | Binding affinity to human adenosine A3 receptor | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID649022 | Selectivity ratio of Ki for human recombinant adenosine A1 receptor to Ki for human recombinant adenosine A2B receptor | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID649026 | Binding affinity to human adenosine A1 receptor | 2012 | Journal of medicinal chemistry, Jan-26, Volume: 55, Issue:2
| Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A₂B adenosine receptor antagonists. |
| AID233615 | Ratio of binding affinities for adenosine A3 and adenosine A2b receptors | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13
| A mild, efficient and alpha-selective glycosidation by using potassium dodecatungstocobaltate trihydrate as catalyst. |
| AID233614 | Ratio of binding affinities for adenosine A2a and adenosine A2b receptors | 2004 | Bioorganic & medicinal chemistry letters, Jul-05, Volume: 14, Issue:13
| A mild, efficient and alpha-selective glycosidation by using potassium dodecatungstocobaltate trihydrate as catalyst. |
| AID325514 | Displacement of [3H]MRE2029F20 from human adenosine A2B receptor expressed in HEK293 cells | 2008 | Bioorganic & medicinal chemistry, Mar-01, Volume: 16, Issue:5
| 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists. |
| AID325513 | Displacement of [3H]MRE3008F20 from human adenosine A3 receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry, Mar-01, Volume: 16, Issue:5
| 1,3-Dipropyl-8-(1-phenylacetamide-1H-pyrazol-3-yl)-xanthine derivatives as highly potent and selective human A(2B) adenosine receptor antagonists. |
| AID1345685 | Human A1 receptor (Adenosine receptors) | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID1345685 | Human A1 receptor (Adenosine receptors) | 2005 | Biochemical pharmacology, Nov-25, Volume: 70, Issue:11
| Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors. |
| AID1345721 | Human A2B receptor (Adenosine receptors) | 2005 | Biochemical pharmacology, Nov-25, Volume: 70, Issue:11
| Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors. |
| AID1345822 | Human A3 receptor (Adenosine receptors) | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID1345618 | Human A2A receptor (Adenosine receptors) | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| AID1345721 | Human A2B receptor (Adenosine receptors) | 2004 | Journal of medicinal chemistry, Mar-11, Volume: 47, Issue:6
| Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |