2-chloroadenosine has been researched along with B-Cell Chronic Lymphocytic Leukemia in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 12 (57.14) | 18.2507 |
| 2000's | 7 (33.33) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Feng, G; Gandhi, V; Krett, NL; McBrayer, SK; Qian, J; Rosen, ST; Shanmugam, M; Yarrington, M | 1 |
| Bednarczyk, D; Kaca, W; Myszka, H; Najder, M | 1 |
| Al-Katib, AM; Beck, FW; Dandashi, MH; Eilender, DS; Godmere, MA; Mohammad, RM; Siddiq, F; Snell, DC | 1 |
| Beutler, E; Carson, DA | 1 |
| Juliusson, G; Liliemark, J | 1 |
| Ames, MM; Li, CY; Reid, JM; Tefferi, A; Witzig, TE | 1 |
| Tefferi, A; Trendle, MC | 1 |
| Amoroso, V; Baccarani, M; Beltrami, CA; Damiani, D; Di Loreto, C; Fanin, R; Infanti, L; Mariuzzi, L; Russo, D; Salmaso, F; Silvestri, F; Zaja, F | 1 |
| Bloński, JZ; Ceglarek, B; Dmoszyńska, A; Dwilewicz-Trojaczek, J; Grieb, P; Hansz, J; Hellmann, A; Holowiecki, J; Kasznicki, M; Komarnicki, M; Konopka, L; Kroll, R; Kuliczkowski, K; Lewandowski, K; Nowak, W; Potoczek, S; Robak, T; Skotnicki, AB; Soroka-Wojtaszko, M; Tomaszewska, A; Zdziarska, B | 1 |
| Al-Katib, AM; Beck, FW; Mohammad, RM; Wall, NR | 1 |
| Blonski, JZ; Gora-Tybor, J; Lech-Miranda, E; Robak, T | 1 |
| Champain, K; Csermak, K; Ganeshaguru, K; Gordon, M; Hart, SM; Hoffbrand, AV; Jones, DT; Man, A; Mehta, AB; Prentice, HG; Virchis, AE; Wickremasinghe, RG | 1 |
| Clausen, NT; Hansen, PB; Larsen, CR | 1 |
| Beutler, E; Carrera, CJ; Carson, DA; Kay, AC; Piro, LD; Saven, A; Thurston, D | 1 |
| Carrera, CJ; Carson, DA; Cottam, HB; Esparza, LM; Kipps, TJ; Wasson, DB | 1 |
| Elmhorn-Rosenborg, A; Juliusson, G; Liliemark, J | 1 |
| Phyliky, RL; Tefferi, A | 1 |
| Gribbin, TE | 1 |
| Beutler, E; Carrera, CJ; Carson, DA; Piro, LD; Saven, A; Terai, C | 1 |
| Beutler, E; Carrera, CJ; Carson, DA; Piro, LD; Wasson, DB | 1 |
4 review(s) available for 2-chloroadenosine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
2-Chlorodeoxyadenosine: hairy cell leukemia takes a surprising turn.
Topics: 2-Chloroadenosine; Apoptosis; Humans; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Lymphocytes; Lymphoma | 1993 |
A clinical update on chronic lymphocytic leukemia. II. Critical analysis of current chemotherapeutic modalities.
Topics: 2-Chloroadenosine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Chlorambucil; Deoxyadenosines; Dose-Response Relationship, Drug; Histocompatibility Testing; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prednisone; Prognosis; Survival Rate; Vidarabine | 1992 |
New purine analogues for the treatment of chronic B-cell malignancies.
Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine | 1991 |
Activity of 2-chloro-2'-deoxyadenosine in chronic lymphocytic leukemia, hairy cell leukemia, and autoimmune hemolytic anemia.
Topics: 2-Chloroadenosine; Adenosine Deaminase; Anemia, Hemolytic, Autoimmune; Cladribine; Deoxyadenosines; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell | 1989 |
4 trial(s) available for 2-chloroadenosine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Phase I study of combined 2-chlorodeoxyadenosine and chlorambucil in chronic lymphoid leukemia and low-grade lymphoma.
Topics: 2-Chloroadenosine; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Deoxyadenosines; Drug Administration Schedule; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Male; Middle Aged; Treatment Outcome | 1994 |
Cladribine with or without prednisone in the treatment of previously treated and untreated B-cell chronic lymphocytic leukaemia - updated results of the multicentre study of 378 patients.
Topics: 2-Chloroadenosine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cladribine; Deoxyadenosines; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Prednisone; Prospective Studies; Survival Analysis | 2000 |
2-Chlorodeoxyadenosine treatment of low-grade lymphomas.
Topics: 2-Chloroadenosine; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bacterial Infections; Bone Marrow Diseases; Cladribine; Deoxyadenosines; Drug Evaluation; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Non-Hodgkin; Male; Middle Aged; Remission Induction; Treatment Outcome | 1992 |
Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine.
Topics: 2-Chloroadenosine; Adult; Antineoplastic Agents; Cladribine; Deoxyadenosines; Drug Resistance; Female; Haptoglobins; Humans; Immunoglobulins; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocyte Count; Lymphocytes; Male; Middle Aged; Remission Induction; Vidarabine | 1992 |
13 other study(ies) available for 2-chloroadenosine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms.
Topics: 2-Chloroadenosine; Adenosine; Cell Line, Tumor; Clinical Trials, Phase I as Topic; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucosephosphate Dehydrogenase; Hematologic Neoplasms; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Multiple Myeloma; Neoplasm Proteins; Pentose Phosphate Pathway; RNA, Neoplasm | 2012 |
Synthesis and induction of apoptosis in B cell chronic leukemia by diosgenyl 2-amino-2-deoxy-beta-D-glucopyranoside hydrochloride and its derivatives.
Topics: 2-Chloroadenosine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Deoxyadenosines; Diosgenin; Glucosamine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Saponins; Structure-Activity Relationship | 2003 |
Factors affecting bryostatin 1-enhanced 2-CdA cytotoxicity in resistant B-cell chronic lymphocytic leukemia.
Topics: 2-Chloroadenosine; 5'-Nucleotidase; Antimetabolites, Antineoplastic; Bryostatins; Cell Death; Deoxyadenosines; Deoxycytidine Kinase; DNA-Activated Protein Kinase; DNA-Binding Proteins; Drug Resistance, Neoplasm; Drug Synergism; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Nuclear Proteins; Protein Serine-Threonine Kinases; ras Proteins; Tumor Cells, Cultured | 2004 |
Retreatment of chronic lymphocytic leukemia with 2-chlorodeoxyadenosine (CdA) at relapse following CdA-induced remission: no acquired resistance.
Topics: 2-Chloroadenosine; Aged; Chlorambucil; Drug Resistance; Erythrocyte Transfusion; Female; Follow-Up Studies; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Male; Middle Aged; Platelet Transfusion; Recurrence; Remission Induction; Time Factors; Vidarabine | 1994 |
Tumor lysis syndrome after treatment of chronic lymphocytic leukemia with cladribine.
Topics: 2-Chloroadenosine; Deoxyadenosines; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Tumor Lysis Syndrome | 1994 |
BCL-2 immunohistochemical evaluation in B-cell chronic lymphocytic leukemia and hairy cell leukemia before treatment with fludarabine and 2-chloro-deoxy-adenosine.
Topics: 2-Chloroadenosine; Adult; Antimetabolites, Antineoplastic; Antineoplastic Agents; Biomarkers, Tumor; Deoxyadenosines; Female; Gene Expression Regulation, Neoplastic; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Proto-Oncogene Proteins c-bcl-2; Vidarabine | 1998 |
Treatment-induced expression of anti-apoptotic proteins in WSU-CLL, a human chronic lymphocytic leukemia cell line.
Topics: 2-Chloroadenosine; Aged; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Bryostatins; Deoxyadenosines; Enzyme Activators; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2001 |
2-chlorodeoxyadenosine (2-CdA) does not change the expression of Fas antigen on chronic lymphocytic leukaemia cells.
Topics: 2-Chloroadenosine; Antimetabolites, Antineoplastic; Deoxyadenosines; fas Receptor; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukocytes, Mononuclear; Tumor Cells, Cultured | 2000 |
Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro.
Topics: 2-Chloroadenosine; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; B-Lymphocytes; Calcium Channel Blockers; Chlorambucil; Deoxyadenosines; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; In Situ Nick-End Labeling; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Proteins; Palatine Tonsil; Protein Kinase C; Staurosporine; Tumor Cells, Cultured; Verapamil; Vidarabine | 2002 |
Aggressive growth of epithelial carcinomas following treatment with nucleoside analogues.
Topics: 2-Chloroadenosine; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Immunosuppressive Agents; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Nucleosides; Vidarabine | 2002 |
Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Animals; Antimetabolites, Antineoplastic; Arabinonucleosides; Cell Death; Cladribine; Clofarabine; Deoxyadenosines; DNA; DNA Damage; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Mice; Mice, SCID; Monocytes | 1992 |
Pentostatin and 2-chlorodeoxyadenosine for hairy-cell leukemia.
Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Pentostatin; Vidarabine | 1992 |
2-Chlorodeoxyadenosine chemotherapy triggers programmed cell death in normal and malignant lymphocytes.
Topics: 2-Chloroadenosine; Cell Death; Cladribine; Deoxyadenosines; DNA; DNA Damage; Humans; In Vitro Techniques; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Nucleosomes; Reference Values | 1991 |