Page last updated: 2024-08-20

2-chloroadenosine and pentostatin

2-chloroadenosine has been researched along with pentostatin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19903 (15.00)18.7374
1990's15 (75.00)18.2507
2000's1 (5.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cheviet, T; Lefebvre-Tournier, I; Peyrottes, S; Wein, S1
Cheson, BD2
Hagberg, H1
Daly, K; Golomb, HM; Mick, R; Ratain, MJ1
Phyliky, RL; Tefferi, A1
Gribbin, TE1
Golde, DW; Lill, MC1
Gutterman, JU; Kurzrock, R; Talpaz, M1
Lichtenstein, LM; Peachell, PT; Schleimer, RP1
Carrera, CJ; Carson, DA; Lotz, M; Piro, LD; Yamanaka, H1
Cronstein, BN; Hirschhorn, R; Kramer, SB; Weissmann, G1
Estey, EH; Jaiyesimi, IA; Kantarjian, HM1
Aykol, S; Bilighan, A; Cayci, B; Doğulu, F; Türközkan, N1
Alekseev, AE; Gomez, LA; Parkinson, SJ; Terzic, A; Wagner, F; Waldman, SA1
Bolam, S; Orchard, JA; Oscier, DG1
Flandrin, G; Maloisel, F; Troussard, X1
Ayres, M; Chen, W; Gandhi, V; Madden, TL; Newman, RA; Rhie, JK1

Reviews

8 review(s) available for 2-chloroadenosine and pentostatin

ArticleYear
Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues.
    Journal of medicinal chemistry, 2019, 09-26, Volume: 62, Issue:18

    Topics: Antimalarials; Biological Transport; Drug Design; Erythrocytes; Humans; Inhibitory Concentration 50; Malaria; Nucleosides; Nucleotides; Plasmodium falciparum; Purines; Pyrimidines

2019
The treatment of hairy cell leukemia: an update.
    Leukemia, 1992, Volume: 6 Suppl 2

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Deoxyadenosines; Humans; Interferon-alpha; Leukemia, Hairy Cell; Pentostatin; Splenectomy

1992
A clinical update on chronic lymphocytic leukemia. II. Critical analysis of current chemotherapeutic modalities.
    Mayo Clinic proceedings, 1992, Volume: 67, Issue:5

    Topics: 2-Chloroadenosine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Chlorambucil; Deoxyadenosines; Dose-Response Relationship, Drug; Histocompatibility Testing; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Prednisone; Prognosis; Survival Rate; Vidarabine

1992
New purine analogues for the treatment of chronic B-cell malignancies.
    Henry Ford Hospital medical journal, 1991, Volume: 39, Issue:2

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Leukemia, Lymphocytic, Chronic, B-Cell; Pentostatin; Vidarabine

1991
Treatment of hairy-cell leukemia.
    Blood reviews, 1990, Volume: 4, Issue:4

    Topics: 2-Chloroadenosine; Antibody Formation; Antineoplastic Agents; Cladribine; Combined Modality Therapy; Deoxyadenosines; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Deficiency Syndromes; Immunologic Factors; Interferon Type I; Leukemia, Hairy Cell; Pentostatin; Remission Induction; Retrospective Studies; Splenectomy

1990
Hairy cell leukaemia: review of treatment.
    British journal of haematology, 1991, Volume: 79 Suppl 1

    Topics: 2-Chloroadenosine; Cladribine; Deoxyadenosines; Granulocyte Colony-Stimulating Factor; Humans; Interferon-alpha; Leukemia, Hairy Cell; Pentostatin; Splenectomy

1991
Advances in therapy for hairy cell leukemia. A review.
    Cancer, 1993, Jul-01, Volume: 72, Issue:1

    Topics: 2-Chloroadenosine; Deoxyadenosines; Forecasting; Granulocyte Colony-Stimulating Factor; Humans; Interferons; Leukemia, Hairy Cell; Male; Pentostatin; Splenectomy; Vidarabine

1993
Hairy cell leukemia. What is new forty years after the first description?
    Hematology and cell therapy, 1998, Volume: 40, Issue:4

    Topics: 2-Chloroadenosine; Antigens, CD; Antimetabolites, Antineoplastic; Antineoplastic Agents; B-Lymphocytes; Bone Marrow; Clinical Trials as Topic; Deoxyadenosines; Humans; Immunologic Factors; Interferon Type I; Leukemia, Hairy Cell; Neoplasm Proteins; Neoplasms, Second Primary; Neoplastic Stem Cells; Pentostatin; Receptors, Antigen, T-Cell, gamma-delta; Recombinant Proteins; Splenectomy; Vidarabine

1998

Trials

1 trial(s) available for 2-chloroadenosine and pentostatin

ArticleYear
Treatment of hairy-cell leukemia.
    Blood reviews, 1990, Volume: 4, Issue:4

    Topics: 2-Chloroadenosine; Antibody Formation; Antineoplastic Agents; Cladribine; Combined Modality Therapy; Deoxyadenosines; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Deficiency Syndromes; Immunologic Factors; Interferon Type I; Leukemia, Hairy Cell; Pentostatin; Remission Induction; Retrospective Studies; Splenectomy

1990

Other Studies

12 other study(ies) available for 2-chloroadenosine and pentostatin

ArticleYear
The purine analogs--a therapeutic beauty contest.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:3

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Deoxyadenosines; Humans; Leukemia; Lymphoma, Non-Hodgkin; Pentostatin; Vidarabine

1992
[Alpha interferon treatment in hairy cell leukemia].
    Nordisk medicin, 1992, Volume: 107, Issue:3

    Topics: 2-Chloroadenosine; Cladribine; Deoxyadenosines; Drug Therapy, Combination; Humans; Interferon-alpha; Leukemia, Hairy Cell; Pentostatin

1992
The purine analogs--a therapeutic beauty contest.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:5

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Deoxyadenosines; Humans; Leukemia; Pentostatin; Vidarabine

1992
Pentostatin and 2-chlorodeoxyadenosine for hairy-cell leukemia.
    The Medical letter on drugs and therapeutics, 1992, Sep-18, Volume: 34, Issue:879

    Topics: 2-Chloroadenosine; Antineoplastic Agents; Cladribine; Clinical Trials as Topic; Deoxyadenosines; Humans; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Non-Hodgkin; Pentostatin; Vidarabine

1992
Lymphoma, hairy-cell leukemia respond to new agents.
    Oncology (Williston Park, N.Y.), 1992, Volume: 6, Issue:9

    Topics: 2-Chloroadenosine; Antibodies, Monoclonal; Deoxyadenosines; Humans; Immunoconjugates; Immunotoxins; Leukemia, Hairy Cell; Lymphoma; Pentostatin; Ricin

1992
Inhibition by adenosine of histamine and leukotriene release from human basophils.
    Biochemical pharmacology, 1989, Jun-01, Volume: 38, Issue:11

    Topics: 2-Chloroadenosine; Adenosine; Basophils; Coformycin; Histamine Release; Humans; In Vitro Techniques; Pentostatin; SRS-A; Structure-Activity Relationship; Theophylline

1989
Profound toxicity of deoxyadenosine and 2-chlorodeoxyadenosine toward human monocytes in vitro and in vivo.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: 2-Chloroadenosine; Cladribine; Deoxyadenosines; DNA Damage; Humans; In Vitro Techniques; Lymphoma; Monocytes; Pentostatin; T-Lymphocytes

1989
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.
    The Journal of experimental medicine, 1983, Oct-01, Volume: 158, Issue:4

    Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Calcimycin; Cell Aggregation; Coformycin; Cytochalasin B; Cytoplasmic Granules; Depression, Chemical; Dipyridamole; Humans; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides

1983
The effects of 2-chloroadenosine and deoxycoformycin on the ATP level, Na-K ATPase activity in experimental brain ischemia of gerbil.
    Neurological research, 1996, Volume: 18, Issue:4

    Topics: 2-Chloroadenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Brain Damage, Chronic; Brain Ischemia; Cell Membrane Permeability; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Gerbillinae; Male; Nerve Tissue Proteins; Neuroprotective Agents; Pentostatin; Sodium-Potassium-Exchanging ATPase

1996
Interruption of Escherichia coli heat-stable enterotoxin-induced guanylyl cyclase signaling and associated chloride current in human intestinal cells by 2-chloroadenosine.
    The Journal of biological chemistry, 1997, Jan-10, Volume: 272, Issue:2

    Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Bacterial Toxins; Caco-2 Cells; Chloride Channels; Enterotoxins; Enzyme Inhibitors; Escherichia coli Proteins; Guanylate Cyclase; Humans; Models, Biological; Pentostatin; Purinergic P1 Receptor Agonists; Signal Transduction

1997
Association of myelodysplastic changes with purine analogues.
    British journal of haematology, 1998, Volume: 100, Issue:4

    Topics: 2-Chloroadenosine; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Deoxyadenosines; Female; Humans; Lymphoproliferative Disorders; Male; Myelodysplastic Syndromes; Pentostatin; Vidarabine

1998
Plasma and cellular pharmacology of 8-chloro-adenosine in mice and rats.
    Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:2

    Topics: 2-Chloroadenosine; Adenosine Deaminase; Adenosine Kinase; Adenosine Triphosphate; Animals; Antimetabolites, Antineoplastic; Biotransformation; Chromatography, High Pressure Liquid; Female; Inosine; Leukocytes, Mononuclear; Male; Mice; Pentostatin; Phosphorylation; Prodrugs; Rats; Rats, Sprague-Dawley; Species Specificity

2002