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2-chloroadenosine and phenylisopropyladenosine

2-chloroadenosine has been researched along with phenylisopropyladenosine in 20 studies

Research

Studies (20)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (30.00)	18.7374
1990's	10 (50.00)	18.2507
2000's	4 (20.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jacobson, KA; van Galen, PJ; Williams, M	1
Daly, JW; Olsson, RA; Secunda, S; Thompson, RD	1
Contardo, N; deJesus, R; Dotson, R; Francis, JE; Ghai, GR; Hutchison, AJ; Moskal, MA; Rovinski, SL; Webb, RL; Yokoyama, R	1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Bruns, RF; Trivedi, BK	1
Bruns, RF; Moos, WH; Szotek, DS	1
Bristol, JA; Bruns, RF; Haleen, SJ; Steffen, RP; Trivedi, BK	1
Bruns, RF	1
Daly, JW	1
Jacobson, KA; Kim, J; Schöneberg, T; van Rhee, AM; Wess, J	1
Bertin, B; Freissmuth, M; Hohenegger, M; Jockers, R; Linder, ME; Marullo, S; Nanoff, C; Strosberg, AD	1
Daly, JW; Olsson, RA; Padgett, WL; Secunda, SI; Thompson, RD	1
Cappellacci, L; Franchetti, P; Grifantini, M; Lucacchini, A; Marchetti, S; Martini, C; Mazzoni, MR; Trincavelli, L	1
Arslan, G; Fredholm, BB; Kull, B; Lorenzen, A; Nilsson, C; Owman, C; Schwabe, U	1
Barbhaiya, H; IJzerman, AP; Rivkees, SA	1
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T	1
Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW	1
Barak, D; Biadatti, T; Chen, W; Gao, ZG; Jacobson, KA; Johnson, CR; Kim, SG; Kim, SK; Lee, K	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Chen, VL; Gao, ZG; Ivanov, AA; Jacobson, KA; Klutz, AM; Wang, B	1

Reviews

2 review(s) available for 2-chloroadenosine and phenylisopropyladenosine

Article	Year
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3 Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship	1992
Adenosine receptors: targets for future drugs. Journal of medicinal chemistry, 1982, Volume: 25, Issue:3 Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines	1982

Other Studies

18 other study(ies) available for 2-chloroadenosine and phenylisopropyladenosine

Article	Year
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. Journal of medicinal chemistry, 1991, Volume: 34, Issue:12 Topics: 2-Chloroadenosine; Animals; Brain; In Vitro Techniques; Rats; Receptors, Purinergic; Structure-Activity Relationship	1991
Highly selective adenosine A2 receptor agonists in a series of N-alkylated 2-aminoadenosines. Journal of medicinal chemistry, 1991, Volume: 34, Issue:8 Topics: Adenosine; Alkylation; Animals; Antihypertensive Agents; Blood Pressure; Chemical Phenomena; Chemistry; Cyclohexanes; Heart Rate; Hypertension; Male; Molecular Structure; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Purinergic	1991
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
C2,N6-disubstituted adenosines: synthesis and structure-activity relationships. Journal of medicinal chemistry, 1989, Volume: 32, Issue:8 Topics: Adenosine; Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Rats; Receptors, Purinergic; Structure-Activity Relationship	1989
N6-cycloalkyladenosines. Potent, A1-selective adenosine agonists. Journal of medicinal chemistry, 1985, Volume: 28, Issue:10 Topics: Adenosine; Animals; Kinetics; Rats; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship	1985
N6-(arylalkyl)adenosines. Identification of N6-(9-fluorenylmethyl)adenosine as a highly potent agonist for the adenosine A2 receptor. Journal of medicinal chemistry, 1988, Volume: 31, Issue:1 Topics: Adenosine; Animals; Brain; Cell Membrane; Coronary Circulation; Fluorenes; Heart Rate; In Vitro Techniques; Indicators and Reagents; Kinetics; Rats; Receptors, Purinergic; Structure-Activity Relationship	1988
Adenosine receptor activation in human fibroblasts: nucleoside agonists and antagonists. Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:6 Topics: Binding, Competitive; Cells, Cultured; Cyclic AMP; Fibroblasts; Humans; Models, Biological; Nucleosides; Proteins; Receptors, Cell Surface; Receptors, Purinergic	1980
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor. The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23 Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1; Structure-Activity Relationship	1995
Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor. The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51 Topics: Animals; Base Sequence; Brain; Cattle; DNA Primers; Escherichia coli; GTP-Binding Proteins; Humans; Molecular Sequence Data; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Species Specificity	1994
Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors. Pharmacology, 1993, Volume: 46, Issue:2 Topics: Adenosine; Adenylyl Cyclases; Animals; Cell Membrane; Cerebral Cortex; Corpus Striatum; Guinea Pigs; Myocardium; PC12 Cells; Radioligand Assay; Rats; Receptors, Purinergic; Species Specificity; Structure-Activity Relationship	1993
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. Journal of medicinal chemistry, 1998, May-07, Volume: 41, Issue:10 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Brain; Cattle; Enzyme Inhibitors; In Vitro Techniques; Male; Membranes; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptor, Adenosine A3; Receptors, Purinergic P1; Testis	1998
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. Biochemical pharmacology, 1999, Jan-01, Volume: 57, Issue:1 Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Cyclic AMP; Humans; Kinetics; PC12 Cells; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyrimidines; Radioligand Assay; Rats; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Recombinant Proteins; RNA, Messenger; Transcription, Genetic; Transfection; Triazoles; Tritium	1999
Identification of the adenine binding site of the human A1 adenosine receptor. The Journal of biological chemistry, 1999, Feb-05, Volume: 274, Issue:6 Topics: Adenine; Amides; Amino Acid Sequence; Amino Acids; Binding Sites; DNA, Complementary; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1	1999
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells. Molecular pharmacology, 1999, Volume: 56, Issue:4 Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines	1999
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine. Molecular pharmacology, 2000, Volume: 58, Issue:6 Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine	2000
Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary. Journal of medicinal chemistry, 2002, Sep-26, Volume: 45, Issue:20 Topics: Adenosine; Animals; Binding, Competitive; CHO Cells; Cricetinae; Epoxy Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Models, Molecular; Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Ribose; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship	2002
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Adenosine; Adenosine A2 Receptor Agonists; Binding Sites; Computer Simulation; Drug Design; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Receptor, Adenosine A2B; Static Electricity; Stereoisomerism	2008