2-chloroadenosine has been researched along with adenosine in 491 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 282 (57.43) | 18.7374 |
| 1990's | 147 (29.94) | 18.2507 |
| 2000's | 48 (9.78) | 29.6817 |
| 2010's | 12 (2.44) | 24.3611 |
| 2020's | 2 (0.41) | 2.80 |
| Authors | Studies |
|---|---|
| Berkich, DA; Dean, RL; Eveleth, D; Hiramatsu, K; Jacobson, KA; Ji, XD; Kassell, NF; Lee, KS; Nikodijevic, O; van Galen, PJ | 1 |
| Daly, JW; Olsson, RA; Secunda, S; Thompson, RD | 1 |
| Arroyo, LH; Olsson, RA; Thompson, RD; Ueeda, M | 1 |
| Bruns, RF; Trivedi, BK | 1 |
| Daly, JW | 1 |
| Cristalli, G; Esker, JL; Jacobson, KA; Ji, XD; Melman, N; Olah, ME; Schneller, SW; Secrist, JA; Siddiqi, SM; Tiwari, KN | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| de Lera Ruiz, M; Lim, YH; Zheng, J | 1 |
| Carlson, EE; Goswami, M; Wilke, KE | 1 |
| Cheviet, T; Lefebvre-Tournier, I; Peyrottes, S; Wein, S | 1 |
| Banerjee, M; Blagg, BSJ; Brackett, CM; Gao, ZG; Jacobson, KA; Jung, YH; Tosh, DK | 1 |
| Narayanan, N; Sulakhe, PV; Wei, JW | 1 |
| DeLapp, NW; Eckols, K | 1 |
| Advenier, C; Candenas, ML; Devillier, P; Naline, E | 2 |
| Hattori, Y; Hayashi, Y; Hori, Y; Lu, YF; Moriwaki, A | 1 |
| Alexander, SP; Dickenson, JM; Hill, SJ; White, TE | 1 |
| Földes, FF; Nagano, O; Nakatsuka, H; Ohta, Y; Reich, D; Sperlagh, B; Vizi, ES | 1 |
| Baulieu, EE; el-Etr, M; Erlanger, BF; Lombes, M | 1 |
| Silinsky, EM; Solsona, CS | 1 |
| Richter, J | 1 |
| Cabantchik, ZI; Eidelman, O; Fox, C; Guay-Broder, C; Jacobson, KA; Pollard, HB; Turner, RJ; van Galen, PJ | 1 |
| Budohoski, L; Opas, M | 1 |
| Borg, I; Henriksson, J; Hickner, RC; Jorfeldt, L; Rosdahl, H; Ungerstedt, U | 1 |
| Berne, RM; Headrick, JP; Hynes, MR; Matherne, GP; Northington, FJ | 1 |
| Henry, JL; Li, H | 3 |
| Kaminski, PM; Proctor, KG | 1 |
| Bartrup, JT; Mackinnon, MW; Morrison, PD; Skett, PG; Stone, TW | 1 |
| Arizono, K; Brady, FO; Garrett, SH; Xiong, X | 1 |
| Hussain, T; Mustafa, SJ | 2 |
| Bozzi, A; Corbo, RM; Ingianna, R; Scacchi, R | 1 |
| Calignano, A; Mancuso, F; Persico, P; Sorrentino, L | 1 |
| Evans, DH | 1 |
| Edbladh, M; Edström, A; Ekström, P | 1 |
| Canela, EI; Casadó, V; Casillas, T; Franco, R; Lluis, C; Mallol, J | 1 |
| Simmons, DA; Winegrad, AI | 1 |
| Cushing, DJ; Makujina, SR; Mustafa, SJ; Sabouni, MH | 2 |
| Amerini, S; Ledda, F; Mantelli, L; Rubino, A | 1 |
| Miller, RJ; Scholz, KP | 1 |
| Plunkett, W; Saunders, PP | 1 |
| Ishimura, Y; Kizaki, H; Suzuki, K; Tadakuma, T | 2 |
| Mohell, N; Nedergaard, J; Unelius, L | 1 |
| Bartrup, JT; Stone, TW | 3 |
| Cordier, J; Delumeau, JC; Glowinski, J; Petitet, F; Prémont, J | 1 |
| Mitsumoto, Y; Mohri, T; Ohkubo, T | 1 |
| Kim, HD; Sohn, DH | 1 |
| Petersen, EN | 1 |
| Dulloo, AG; Girardier, L; Seydoux, J | 1 |
| Beninger, RJ; Josselyn, SA | 1 |
| Adams-Brotherton, A; Clancy, GP; Husted, RF; Stokes, JB | 1 |
| Barron, HV; Forrest, JN; Kelley, GG; Poeschla, EM | 1 |
| Brown, J; Kwok, YN; McIntosh, C | 1 |
| Baldessarini, RJ; Booth, RG | 1 |
| Ibayashi, S; Meno, JR; Ngai, AC; Winn, HR | 1 |
| Do, UH; Jarvis, MF; Sills, MA; Williams, M | 1 |
| Kulkarni, SK; Thorat, SN | 1 |
| Chambaut-Guerin, AM; Delbourg, I; Ribier, A; Thomopoulos, P; Ventura, MA | 1 |
| Barrett, KE; Cohn, JA; Dharmsathaphorn, K; Huott, PA; Wasserman, SI | 1 |
| Rabin, RA | 2 |
| Frew, R; Hamilton, MG; Lundy, PM | 1 |
| Hattori, Y | 1 |
| Ferroni, S; Mager, R; Schubert, P | 1 |
| Barclay, BW; McNeal, RB; Webb, RL; Yasay, GD | 1 |
| Alabadí, JA; Alborch, E; Alvarez, C; Miranda, FJ; Salom, JB; Torregrosa, G | 1 |
| de Mendonça, A; Ribeiro, JA | 2 |
| Shaw, JS; Stoggall, SM | 1 |
| Lothman, EW; Stringer, JL | 1 |
| Contreras, E; Germany, A; Villar, M | 1 |
| Mustafa, SJ; Ramagopal, MV; Sabouni, MH | 1 |
| Chapal, J; Loubatières-Mariani, MM; Petit, P; Roye, M | 1 |
| Firth, JL; Kendall, DA | 1 |
| Ballati, L; Manzini, S | 1 |
| Churchill, PC; Wu, PH | 1 |
| Kitos, TE; Michaelis, ML; Mooney, T | 1 |
| Gerber, JG; Nies, AS; Payne, NA | 1 |
| Dzierzanowski, D; McCarthy, L; Schimmel, RJ | 1 |
| Daly, JW; Gusovsky, F | 1 |
| Hoskins, DD; Vijayaraghavan, S | 1 |
| Daly, JW; de la Cruz, RA; Gusovsky, F; Hollingsworth, EB; Sears, EB | 1 |
| Birch, RE; Polmar, SH | 1 |
| Clancy, G; Pratt, AD; Welsh, MJ | 1 |
| Dolphin, AC; Forda, SR; Scott, RH | 1 |
| Kelly, E; Nahorski, SR | 1 |
| Condorelli, M; Kagey-Sobotka, A; Lichtenstein, LM; Marone, G; Triggiani, M | 1 |
| Fox, IH; John, D | 2 |
| Brown, SJ; Richardson, PJ | 1 |
| Edwards, RJ; MacDermot, J; Wilkins, AJ | 1 |
| Barbenel, JC; Forbes, CD; Lowe, GD; Madhok, R; Saniabadi, AR; Shaw, B; Spowart, K | 1 |
| Paes de Carvalho, R; Ventura, AL | 1 |
| Brady, MJ; Nairn, AC; Nichols, RA; Palfrey, HC | 1 |
| Beek, D; Kenakin, TP | 1 |
| Addae, JI; Stone, TW | 1 |
| Berry-Kravis, E; Dawson, G; Derechin, V; Kazmierczak, BI | 1 |
| Ribeiro, JA; Sebastião, AM | 4 |
| Adams, RN; Johe, KK; Michaelis, ML; Moghadam, B | 1 |
| Lichtenstein, LM; Peachell, PT; Schleimer, RP | 1 |
| Cirillo, R; Genovese, A; Marino, O; Marone, G; Quattrin, S | 1 |
| Blair, TA; Murray, TF; Parenti, M | 1 |
| Cushing, DJ; Mustafa, SJ; Sabouni, MH | 1 |
| Grome, JJ; Harper, AM; McBean, DE | 1 |
| Duman, RS; Enna, SJ; Strada, SJ | 1 |
| Johnson, GV; Jope, RS; Li, XH | 1 |
| Baldwin, HA; File, SE | 1 |
| Azuma, I; Iida, J; Ishihara, C; Mizukoshi, N; Nishi, N; Saiki, I; Tokura, S | 1 |
| Aosaki, T; Kasai, H | 1 |
| Lloyd, HG; Perkins, A; Spence, I | 1 |
| Hiraishi, H; Ivey, KJ; Kurachi, Y; Mutoh, H; Ota, S; Shimada, T; Sugimoto, T; Terano, A | 1 |
| Borish, L; Joseph, B; Rocklin, RE; Sustiel, AM | 1 |
| Cordier, J; el-Etr, M; Glowinski, J; Prémont, J; Torrens, Y | 1 |
| de Mello, FG; Paes de Carvalho, R | 2 |
| d'Almeida, MS; Lautt, WW; Legare, DJ | 1 |
| Isono, K; Osada, H | 3 |
| Dobson, JG; Frohloff, N; LaMonica, DA | 1 |
| Mustafa, SJ; Sabouni, MH | 1 |
| Hargittai, PT; Lieberman, EM; Mustafa, SJ; Sabouni, MH | 1 |
| Franklin, PH; Murray, TF; Tripp, ED; Zhang, G | 1 |
| Barankiewicz, J; Cheung, R; Cohen, A; Dosch, HM | 1 |
| Cardinali, DP; Pereyra, EN; Sarmiento, MI; Vacas, MI | 1 |
| Fredholm, BB; Jansson, PA; Lönnroth, P; Smith, U | 1 |
| Cordier, J; el-Etr, M; Glowinski, J; Premont, J | 1 |
| Billington, CJ; Grace, M; Krahn, DD; Levine, AS | 1 |
| Ellis, EF; Haberl, RL; Heizer, ML | 1 |
| Chen, H; Dryden, WF; Singh, YN | 2 |
| Belardinelli, L; Belloni, FL; Halperin, C; Hintze, TH | 1 |
| Berne, RM; Park, TS; Rubio, R; Van Wylen, DG | 1 |
| de la Harpe, J; Nathan, CF | 1 |
| Geiger, JD; Westerberg, VS | 1 |
| Burnstock, G; Reilly, WM; Saville, VL | 1 |
| Gharib, A; Ou, L; Pacheco, H; Reynaud, D; Sarda, N | 1 |
| Fredholm, BB; Lerner, UH; Sahlberg, K | 1 |
| Billig, H; Rosberg, S; Thelander, H | 1 |
| Jacobson, B; Lerner, A; Miller, RA | 1 |
| Brown, AM; Donaldson, J; Hill, SJ | 1 |
| Reinhardt, RR; Wecker, L | 1 |
| Jackson, EK; Kuan, CJ | 1 |
| Hayashi, H; Inoue, K; Kato, T; Kudo, I; Nojima, S; Nozawa, R | 1 |
| Birch, PJ; Fillenz, M | 1 |
| McCarthy, L; Schimmel, RJ | 2 |
| Coleman, DL; Downs, SM; Eppig, JJ | 1 |
| Magistretti, PJ; Ofori, S; Schorderet, M | 1 |
| Enna, SJ; Karbon, EW; Shenolikar, S | 1 |
| Benishin, CG; Cooper, JR; Pearce, LB | 3 |
| Mott, J; Sherman, AD | 1 |
| Doak, N; Fleming, WW; Leedham, JA; Taylor, DA | 1 |
| Echizen, H; Ishizaki, T; Itoh, R | 1 |
| Bruns, RF; Fox, IH; Hutchison, K; Prasad, M; Work, C | 1 |
| Churchill, MC; Churchill, PC | 1 |
| Broadley, KJ; Broome, S; Paton, DM | 1 |
| Chin, JH; DeLorenzo, RJ; Mashman, WE | 1 |
| Gustafsson, LE; Hedqvist, P; Lundin, J; Wiklund, NP | 1 |
| Schwarz, M; Sontag, KH; Turski, L; Turski, WA | 1 |
| Holloway, WR; Thor, DH | 1 |
| Daly, JW; Hollingsworth, EB; Sears, EB | 1 |
| Cronstein, BN; Hirschhorn, R; Kramer, SB; Rosenstein, ED; Weissmann, G | 1 |
| Fredholm, BB; Li, YO | 1 |
| Cervenka, J; Eikvar, L; Hansson, V; Jutte, NH; Levy, FO; Yoganathan, T | 1 |
| Burton, JL; Creveling, CR; Daly, JW; Hollingsworth, EB; McNeal, ET; Williams, RJ | 1 |
| Jackson, MB; Trussell, LO | 1 |
| Kulkarni, SK; Mehta, AK | 4 |
| Forrest, JN; Handler, JS; Lang, MA; Preston, AS | 1 |
| Daly, JW; Hollingsworth, EB | 1 |
| Hamburger-Bar, R; Newman, ME | 1 |
| Chin, JH; Delorenzo, RJ | 2 |
| Gustafsson, LE; Samuelson, UE; Wiklund, NP | 1 |
| Daly, JW; Hollingsworth, EB; Ukena, D | 1 |
| Daly, JW; De la Cruz, RA; Hollingsworth, EB | 1 |
| Bloomfield, MR; Fillenz, M | 1 |
| Elliott, ME; Schimmel, RJ | 1 |
| Bruns, RF; Lu, GH; Pugsley, TA | 1 |
| Fredholm, BB; Jonzon, B; Lindström, K | 1 |
| Samet, MK | 2 |
| Bazil, CW; Minneman, KP | 1 |
| Sawynok, J; Sweeney, MI; White, TD | 1 |
| Murray, TF; Schultz, CS; Sylvester, D; Szot, P | 1 |
| de Bruijn, CH; Dinjens, WN; Roos, D; van Doorn, R; van Laarhoven, JP; Zeijlemaker, WP | 1 |
| Conley, NS; Zeidler, RB | 1 |
| Duman, RS; Enna, SJ | 1 |
| Consolo, S; Fisone, G; Forloni, GL; Ladinsky, H | 1 |
| Dzierzanowski, D; Elliott, ME; Honeyman, TW; Schimmel, RJ | 1 |
| Cronstein, BN; Hirschhorn, R; Kubersky, SM; Weissmann, G | 1 |
| Fredholm, BB; Nordstedt, C | 1 |
| Gilfillan, AM; Rooney, SA | 1 |
| Brodie, MS; Dunwiddie, TV; Fredholm, BB; Lee, K; Ståhle, L | 1 |
| Hasday, JD; Sitrin, RG | 1 |
| Tse, SY; Wei, ET | 1 |
| Cullen, JJ; Welsh, MJ | 1 |
| Klabunde, RE | 1 |
| Arai, S; Fujii, Y; Kimura, S; Sendo, F | 1 |
| Kaufman, MP; Rotto, DM | 1 |
| Fulton, AM | 1 |
| Johnston, GA; Lloyd, HG; Spence, I | 1 |
| Bjur, RA; Shinozuka, K; Westfall, DP | 1 |
| Buxton, IL; Smith, MA; Westfall, DP | 1 |
| Brown, SJ | 1 |
| Arvin, B; Neville, LF; Roberts, PJ | 1 |
| Silinsky, EM | 3 |
| Brun-Marmillon, J; Claustrat, B; Collin, JP; Falcón, J | 1 |
| Mohrman, DE | 1 |
| Stone, TW | 1 |
| Basuyau, JP; Chedeville, A; Claeyssens, S; Hamet, M; Lavoinne, A | 1 |
| Blakeley, AG; Dunn, PM; Petersen, SA | 1 |
| Franklin, PH; Gale, K; Murray, TF; Tripp, ED; Zhang, G | 1 |
| Coffin, VL; Spealman, RD | 2 |
| Cheung, WT; Lee, CM; Ng, TB | 1 |
| Harper, AM; McBean, DE; Rudolphi, KA | 1 |
| Clark, RL; Cusick, WA; Eschbach, K; Heyse, JF | 1 |
| Hardebo, JE; Kåhrström, J; Owman, C | 1 |
| Evans, MC; Meldrum, BS; Swan, JH | 1 |
| Holz, FG; Steinhausen, M | 1 |
| Altom, MG; Schultz, RM | 1 |
| Monteiro, EC; Ribeiro, JA | 1 |
| Granger, JP; Knox, FG; Pawlowska, D | 1 |
| Clanachan, AS; Heaton, TP | 1 |
| Harding, SE; Harris, P; Hopwood, AM | 2 |
| Proctor, KG | 1 |
| Burnstock, G; Delbro, D | 1 |
| Cote, DT; Dotson, RA; Francis, JE; Ghai, G; Goodman, FR; Hopkins, MF; Williams, M; Zimmerman, MB | 1 |
| Collis, MG; Jacobson, KA; Tomkins, DM | 1 |
| Barbenel, JC; Forbes, CD; Lowe, GD; Saniabadi, AR | 1 |
| Ferrario, P; Mantegazza, P; Zambotti, F; Zecca, L; Zonta, N | 1 |
| Buc, HA; Cépanec, C; Demaugre, F; Leroux, JP; Moncion, A | 1 |
| Bowker, HM; Chapman, AG | 1 |
| Belanoff, J; Cronstein, BN; Hirschhorn, R; Levin, RI; Weissmann, G | 1 |
| Barraco, RA; Campbell, WR; Marcantonio, DR; Phillis, JW; Salah, RS | 1 |
| Ades, EW; Altom, MG; DeLong, DC; Schultz, RM; Tang, JC | 1 |
| Kamatani, N; Mikanagi, K; Nishida, Y; Nishioka, K; Nobori, T; Yamanaka, H | 1 |
| Campbell, AK; Patel, AK | 1 |
| Kenakin, TP; Pike, NB | 1 |
| Erfurth, A; Lee, KS; Reddington, M | 1 |
| Dóra, E; Kovách, AG | 1 |
| Fredholm, BB; Lerner, U | 3 |
| Bortolotto, ZA; Cavalheiro, EA; Ikonomidou, C; Mello, LE; Turski, L; Turski, WA | 1 |
| Nagahata, H; Noda, H | 1 |
| Jarvis, SM | 1 |
| Longnecker, DE; Seyde, WC | 1 |
| Saito, T; Yamaguchi, J | 1 |
| Campbell, AK; Morgan, BP; Roberts, PA | 1 |
| Barr, E; Daniell, LC; Leslie, SW | 1 |
| Belardinelli, L; West, GA | 1 |
| Campbell, AK; Hallett, MB; Newby, AC; Roberts, PA | 1 |
| Dóra, E | 1 |
| Jarvis, SM; Martin, BW; Ng, AS | 1 |
| Fukuda, H; Ishida, Y; Kotani, M; Moritoki, H; Takei, M; Ueyama, T | 1 |
| Bortolotto, ZA; Cavalheiro, EA; Mello, LE; Turski, L | 1 |
| Corcoran, T; Huffaker, T; Wagner, JA | 1 |
| Churchill, PC; Murray, RD | 1 |
| Budohoski, L; Challiss, RA; Lozeman, FJ; McManus, B; Newsholme, EA | 1 |
| Collier, HO; Plant, NT; Tucker, JF; von Uexküll, A | 1 |
| Devreotes, PN; Theibert, A | 1 |
| Fredholm, BB; Jonzon, B | 1 |
| Watanabe, Y; Yoshida, H | 1 |
| Block, T; Breckenridge, BM; Kon, C | 1 |
| Elfman, L; Fredholm, BB; Lindgren, E; Walum, E | 1 |
| Alkadhi, KA; Brown, TR; Sabouni, MH | 1 |
| Gustafsson, LE | 1 |
| Mantegazza, P; Tammiso, R; Zambotti, F; Zecca, L; Zonta, N | 1 |
| Chapal, J; Loubatières-Mariani, MM; Roye, M; Zerbib, A | 1 |
| Berezo, MW; Erny, RE; Perlman, RL | 1 |
| Blaker, WD; Cheney, DL; Costa, E; Murray, TF | 1 |
| Bourke, RS; Church, G; Dazé, M; Kimelberg, HK | 1 |
| McGee, R; Rabe, CS | 1 |
| Archer, ER; Dolphin, AC | 1 |
| Burnstock, G; Meldrum, LA; Sneddon, P | 1 |
| Galloway, MP; Roth, RH | 1 |
| Budohoski, L; Challiss, RA; McManus, B; Newsholme, EA | 1 |
| Dobbins, JW; Forrest, JN; Laurenson, JP | 1 |
| De Lucia, R; McIlwain, H; Newman, ME; Patel, J | 1 |
| Kobayashi, K; Kuroda, Y; Yoshioka, M | 1 |
| Deeprose, RD; Duncan, GS; Schmitges, CJ; Wolberg, G; Zimmerman, TP | 1 |
| Behrman, HR; Hall, AK; Preston, SL | 1 |
| Clanachan, AS | 1 |
| Kenimer, JG; Nirenberg, M | 1 |
| Lee, KS; Reddington, M; Schubert, P | 1 |
| Friis, RR; Glossman, H; Howard, RF; Sheppard, JR | 1 |
| Phillis, JW; Wu, PH | 1 |
| Brown, CM; Collis, MG | 1 |
| Perrin, MH; Smith, MA; Vale, WW | 1 |
| Cummins, CJ; Lust, WD; Passonneau, JV | 1 |
| Taylor, DA; Williams, M | 1 |
| Dobson, JG | 1 |
| Lal, H; Spencer, DG | 1 |
| Fox, IH; Kurpis, L | 1 |
| Henon, BK; McAfee, DA | 1 |
| Buckley, N; Burnstock, G | 1 |
| Butts-Lamb, P; Daly, JW; Padgett, W | 1 |
| Cronstein, BN; Hirschhorn, R; Kramer, SB; Weissmann, G | 1 |
| Dolphin, AC | 1 |
| Snyder, SH | 1 |
| Kamino, Y; Lai, RT; Watanabe, Y; Yoshida, H | 1 |
| Narahashi, T; Tsunoo, A | 1 |
| Bartrons, R; Hers, HG; Van Schaftingen, E | 1 |
| Kamatani, N; Mikanagi, K; Nishida, Y; Nishioka, K; Yamanaka, H | 1 |
| Kagiya, T; Kaminoh, Y; Kawabata, H; Watanabe, Y; Yoshida, H | 1 |
| Barber, R; Butcher, RW; Goka, TJ | 1 |
| Burnstock, G; Crowe, R; Kennedy, C; Török, J | 1 |
| Bidani, AK; Churchill, MC; Churchill, PC; Prada, J | 1 |
| Kamatani, N; Miyamoto, T; Morito, T; Nishida, Y | 1 |
| Breese, GR; Mueller, RA; Widerlöv, E | 1 |
| Armstrong, I; Wagner, J; Wu, N | 1 |
| Isono, K; Koyama, T; Kusakabe, H; McCloskey, JA; Miyata, N; Sethi, SK; Ubukata, M; Uramoto, M | 1 |
| Altman, HJ; Barraco, RA; Coffin, VL; Phillis, JW | 1 |
| Consolo, S; Fisone, G; Forloni, GL; Ladinsky, H; Sieklucka, M | 1 |
| Helland, S; Schanche, JS; Schanche, T; Ueland, PM | 1 |
| Dragunow, M; Goddard, GV | 1 |
| Huang, M; Rorstad, OP | 1 |
| Beck, DW; Cancilla, PA; Hart, MN; Henn, FA; Vinters, HV | 1 |
| Albertson, TE; Bowyer, JF; Joy, RM; Stark, LG | 1 |
| Brown, C; Burnstock, G; Cusack, NJ; Meghji, P; Moody, CJ | 1 |
| Fondacaro, JD; Jacobson, ED; Schwaiger, M; Walus, KM | 1 |
| Ansell, J; Cassidy, J; Czernik, AJ; Petrack, B | 1 |
| Goto, F; Goto, K; Nakamura, S; Yoshinaga, M | 1 |
| Churchill, PC | 1 |
| Kenakin, TP | 1 |
| Beppu, T; Takahashi, E | 1 |
| Fujisawa, H; Kumazawa, Y; Nishimura, C; Ohtani, A | 1 |
| Bristol, JA; Evans, DB; Schenden, JA | 1 |
| Chiang, PK; Guranowski, A; Segall, JE | 1 |
| Michaelis, EK; Michaelis, ML | 1 |
| Fredholm, BB; Sollevi, A | 1 |
| Haubrich, DR; Williams, M; Wood, PL; Yarbrough, GG | 1 |
| Crawley, JN; Marangos, PJ; Patel, J | 1 |
| Risley, EA; Williams, M | 1 |
| Balls, K; Phillis, JW; Rinaldi, B; Wu, PH | 1 |
| Makujina, SR; Mustafa, SJ | 1 |
| Barankiewicz, J; Bullough, DA; Erion, MD; Firestein, GS; Gruber, HE; Jimenez, R; Mullane, KM; Ramirez-Weinhouse, M; Smith, CW | 1 |
| Dolphin, AC; Sweeney, MI | 1 |
| Bhardwaj, A; Hanley, DF; Koehler, RC; Northington, FJ; Stiefel, T; Traystman, RJ | 1 |
| Burnstock, G; Ralevic, V; Rubino, A | 1 |
| Kabuto, H; Liu, J; Mori, A; Toma, J; Yokoi, I | 1 |
| Heistad, DD; Loftus, CM; Muhonen, MG | 1 |
| de Mendonça, A; Ribeiro, JA; Sebastião, AM | 1 |
| Challiss, RA; Morgan, AJ; Murray, KJ | 1 |
| Stefanović, V; Vlahović, P | 1 |
| Hargittai, PT; Lieberman, EA; Mustafa, SJ; Olanrewaju, HA | 1 |
| Hashimoto, T; Ishii, R; Kunitomo, M; Shinozuka, K; Takeuchi, K | 1 |
| Szondy, Z | 1 |
| Elnazir, BK; Marshall, JM; Thomas, T | 1 |
| Brunelleschi, S; Dianzani, C; Fantozzi, R; Viano, I | 1 |
| Bellingham, MC; Berger, AJ | 1 |
| Chiba, S; Furukawa, Y; Kasama, M; Oguchi, T; Sawaki, S | 1 |
| Kitano, I; Matsunaga, T; Mori, N; Nario, K | 1 |
| Dehpour, AR; Ghafourifar, P; Jabbary, M; Shadan, F | 1 |
| Alexander, SP; Hill, SJ; Kendall, DA; Losinski, A | 1 |
| Hill, SJ; Peakman, MC | 1 |
| Bendall, MR; Faden, AI; Headrick, JP; Vink, R | 1 |
| Handforth, A; Treiman, DM | 1 |
| Blazynski, C; McIntosh, HH | 1 |
| Marshall, JM; Thomas, T; Turner, L | 1 |
| Hunt, RH; Muller, MJ; Prior, T; Rangachari, PK | 1 |
| Cunha, RA; Milusheva, E; Ribeiro, JA; Sebastião, AM; Vizi, ES | 1 |
| Hattori, Y; Hayashi, Y; Hori, Y; Islam, N; Moriwaki, A | 1 |
| Hunt, JM; Silinsky, EM | 1 |
| Hattori, Y; Hayashi, Y; Hori, Y; Moriwaki, A | 1 |
| Barajas-López, C | 1 |
| Belloni, FL; Hernandez, A; Lee, HT; Lewy, JL; Thompson, CI | 1 |
| Fiorella, D; Rabin, RA; Van Wylen, DG | 1 |
| Duncan, AE; Fraser, LR | 1 |
| Baudendistel, LJ; Dahms, TE; Marts, BC; Naunheim, KS | 1 |
| Flückiger-Isler, RE; Walter, P | 1 |
| Dickenson, JM; Hill, SJ; Megson, AC; Townsend-Nicholson, A | 1 |
| Collin, JP; Falcón, J; Van Camp, G | 1 |
| Broad, RM; Fredholm, BB | 1 |
| Arfors, KE; Bardenheuer, HJ; Chambers, JD; Chouker, A; Fischer, S; Peter, K; Thiel, M; Zourelidis, C | 1 |
| Constantino, MD; Cunha, RA; Fredholm, BB; Johansson, B; Sebastião, AM | 1 |
| Barajas-López, C; Espinosa-Luna, R; Peres, AL | 1 |
| Anderson, GF; Barraco, RA; Helfman, CC; Zhong, H | 1 |
| Hettinger-Smith, BD; Leid, M; Murray, TF | 1 |
| Clotz, MA; Haun, SE; Horrocks, LA; Segeleon, JE; Trapp, VL | 1 |
| Burnstock, G; Höpker, VH; Saffrey, MJ | 1 |
| Endou, H; Kurokawa, K; Miyanoshita, A; Nishi, T; Nosaka, K; Suzuki, K; Takahashi, T | 1 |
| Atmaca, M; Fry, JR | 1 |
| Alekseev, AE; Gomez, LA; Parkinson, SJ; Terzic, A; Wagner, F; Waldman, SA | 1 |
| Fredholm, BB; Jin, S | 1 |
| Elnazir, B; Kumar, P; Marshall, JM | 1 |
| Monteiro, EC; Monteiro, TC; Silva e Sousa, MA; Vera-Cruz, P | 1 |
| Kataoka, K; Nakamura, Y; Si, QS | 1 |
| Holzer, K; Kreimeier, U; Messmer, K; Moritz, S; Peter, K; Thiel, M | 1 |
| Blay, J; Hoskin, DW; Williams, BA | 1 |
| Chopde, CT; Ghosh, AK; Mandhane, SN | 1 |
| Buxton, IL; Cheek, DJ; Smith, AD; Westfall, DP | 1 |
| Ikeda, U; Kurosaki, K; Okada, K; Saito, T; Shimada, K; Shimpo, M | 1 |
| Barth, A; Janigro, D; Meno, JR; Newell, DW; Nguyen, LB; Wender, R; Winn, HR | 1 |
| Abebe, W; Mustafa, SJ | 1 |
| Neher, M; Schneider, A; Schwaninger, M; Spranger, M; Viegas, E | 1 |
| Ikeda, U; Kurosaki, K; Ohya, K; Shimada, K | 1 |
| Ali, S; Metzger, WJ; Mustafa, SJ; Olanrewaju, HA | 1 |
| Alexander, SP; Cooper, J; Hill, SJ | 1 |
| Carré, DA; Civan, MM; Coca-Prados, M; Mitchell, CH; Peterson-Yantorno, K | 1 |
| Koch, H; Starke, K; von Kügelgen, I | 1 |
| George, B; Kulkarni, SK | 1 |
| Keef, KD; Mutafova-Yambolieva, VN | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK | 3 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z | 1 |
| Cunha, RA; Gonçalves, ML; Ribeiro, JA | 1 |
| Kaputlu, I; Ozdem, S; Sadan, G | 1 |
| Avoli, M; D'Antuono, M; Nehlig, A; Tancredi, V | 1 |
| Greene, DA; Kato, K; Nakamura, J; Stevens, MJ; Thomas, TP | 1 |
| Fallahi, M; Mirnajafi-Zadeh, J; Palizvan, MR; Pourgholami, MH; Rostampour, M | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Shue, H | 1 |
| Campos, BG; Ferreira, RR; Gomes, JC | 1 |
| Gauthier, NS; Headrick, JP; Matherne, GP; Morrison, RR | 1 |
| Hashikawa, T; Kamatani, T; Murakami, S; Okada, H; Saho, T; Shimabukuro, Y; Terakura, M | 1 |
| Abbracchio, MP; Camurri, A; Ceruti, S; Falzano, L; Fiorentini, C; Frank, C; Giammarioli, AM; Malorni, W; Rufini, S | 1 |
| Feoktistov, I; Mustafa, SJ; Olanrewaju, HA; Qin, W; Scemama, JL | 1 |
| de la Lande, IS; Krishna, M; Marino, V; Narayanan, A; Parker, DA | 1 |
| Dhalla, AK; Dodam, JR; Johnson, LR; Jones, AW; Laughlin, MH; Magliola, L; Rubin, LJ | 1 |
| Hourani, SM; Prentice, DJ | 1 |
| Farroni, JS; McCool, BA | 1 |
| Dubey, RK; Gillespie, DG; Jackson, EK; Mi, Z; Zacharia, LC | 1 |
| Kubota, Y; Kunitomo, M; Kwon, YM; Nakamura, K; Shinozuka, K; Tanaka, N; Tanioka, Y | 1 |
| Ishii-Nozawa, R; Kunitomo, M; Matsuda, A; Minakawa, N; Nakata, H; Shinozuka, K; Takeuchi, K | 1 |
| Georgiev, V; Kambourova, T; Tchekalarova, J | 1 |
| Graham, SH; Hendrich, KS; Ho, C; Jackson, EK; Kochanek, PM; Marion, DW; Melick, JA; Robertson, CL; Williams, DS | 1 |
| Flood, A; Headrick, JP | 1 |
| Bradley, KK; Bradley, ME | 1 |
| Delbro, DS; Giglio, D; Tobin, G | 1 |
| Hashikawa, T; Murakami, S; Nozaki, T; Okada, H; Saho, T; Shimabukuro, Y; Takedachi, M | 1 |
| Morrison, RR; Mustafa, SJ; Talukder, MA | 1 |
| Harris, AL; Houlbrook, S; Priddle, JD; Robbins, SK | 1 |
| Hou, T; Li, M; Li, Z; Wang, Q; Zhang, L; Zhang, Q; Zhao, J | 1 |
| Lambert, NA; Wetherington, JP | 1 |
| Hayashi, N; Kitamura, N; Kosaka, H; Koshiba, M; Kumagai, S; Nakazawa, T; Saura, R | 1 |
| Costenla, AR; de Mendonça, A; Ribeiro, JA | 1 |
| Flood, AJ; Headrick, JP; Willems, L | 1 |
| Ferroni, S; Marchini, C; Ogata, T; Schubert, P | 1 |
| Clark, RS; Dixon, CE; Griffith, RP; Jackson, EK; Jenkins, LW; Kochanek, PM; Melick, JA; Peters, GW; Vagni, VA; Varma, MR | 1 |
| Hague, BF; Kindt, TJ; Zhao, TM | 1 |
| CLARKE, DA; PHILIPS, FS; STERNBERG, SS | 1 |
| COBBIN, LB; THORP, RH | 1 |
| THORP, RH | 1 |
| BORN, GV; HONOUR, AJ; MITCHELL, JR | 1 |
| Abebe, W; Mozaffari, MS | 1 |
| Alloisio, S; Cugnoli, C; Ferroni, S; Nobile, M | 1 |
| Carroll, MA; Falck, JR; Ferreri, NR; Liclican, EL; McGiff, JC; Pedraza, PL | 1 |
| Hendrich, KS; Ho, C; Jackson, EK; Janesko, KL; Kochanek, PM; Melick, JA; Shore, PM; Wisniewski, SR; Zacharia, L | 1 |
| Gorelik, E; Huang, X; Jackson, EK; Raskovalova, T; Sitkovsky, M; Zacharia, LC | 1 |
| Coelho, JE; Cunha, RA; de Mendonça, A; Fragata, I; Rebola, N; Ribeiro, JA | 1 |
| Ashton, KJ; Blackburn, MR; Chunn, JL; Headrick, JP; Molina, JG; Reichelt, ME; Schnermann, J; Sun, CX; Willems, L | 1 |
| Fragata, IR; Ribeiro, JA; Sebastião, AM | 1 |
| Gorelik, E; Huang, X; Jackson, EK; Lokshin, A; Raskovalova, T; Zacharia, LC | 1 |
| Ashton, KJ; Blackburn, MR; Headrick, JP; Matherne, GP; Peart, JN; Reichelt, ME; Willems, L | 1 |
| Carneiro, FS; Giachini, FR; Inscho, EW; Leite, R; Tostes, RC; Webb, RC | 1 |
| Gorelik, E; Huang, X; Jackson, EK; Lokshin, A; Mandic, M; Raskovalova, T; Su, Y; Zarour, HM | 1 |
| Kubota, Y; Kunitomo, M; Mizuno, H; Morikawa, T; Nakamura, K; Shinozuka, K; Tanaka, N | 1 |
| Fredholm, BB; Herling, AW; Johansson, SM; Lindgren, E; Yang, JN | 1 |
| Ayres, ML; Chen, LS; Gandhi, V; Krett, NL; Nowak, BJ; Rosen, ST; Zhang, S | 1 |
| Bache, RJ; Chen, Y; Fassett, JT; French, J; Hu, X; Xu, X; Zhu, G | 1 |
| Blackburn, MR; Ellis, NA; Headrick, JP; Reichelt, ME; Shanu, A; Willems, L; Witting, PK | 1 |
| Correia, AM; Pousinha, PA; Ribeiro, JA; Sebastião, AM | 1 |
| Glaumann, C; Grishina, VA; Gustafsson, LE; Nilsson, KF | 1 |
| Boison, D; Boon, P; Pil, K; Raedt, R; Van Dycke, A; Verstraete, A; Vonck, K | 1 |
| Maguma, H; Taylor, DA; Thayne, K | 1 |
| Broz, V; Dolezal, V; Fleischmannova, J; Kucerova, L; Santruckova, E; Sidorov, R; Zurovec, M | 1 |
| Feng, G; Gandhi, V; Krett, NL; McBrayer, SK; Qian, J; Rosen, ST; Shanmugam, M; Yarrington, M | 1 |
| Chan, J; Deng, Z; He, L; Qi, J; Tao, W; Xu, W; Zhao, C | 1 |
| Dubey, RK; Fingerle, J; Gillespie, DG; Imthurn, B; Jackson, EK; Mi, Z; Rosselli, M | 1 |
| Emoto, M; Fujimoto, K; Inaba, M; Kakutani, Y; Miki, Y; Morioka, T; Shioi, A; Shoji, T | 1 |
| Cottrell, KA; Dizon, MG; Torres, LS; Weber, JD | 1 |
5 review(s) available for 2-chloroadenosine and adenosine
| Article | Year |
|---|---|
Adenosine receptors: targets for future drugs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Humans; Ligands; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Xanthines | 1982 |
Adenosine A2A receptor as a drug discovery target.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction | 2014 |
Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues.
Topics: Antimalarials; Biological Transport; Drug Design; Erythrocytes; Humans; Inhibitory Concentration 50; Malaria; Nucleosides; Nucleotides; Plasmodium falciparum; Purines; Pyrimidines | 2019 |
Metabolism and action of purine nucleoside analogs.
Topics: 2-Chloroadenosine; Adenosine; Cladribine; Deoxyadenosines; Guanine; Guanosine; Humans; Purine Nucleosides; Ribavirin; Vidarabine | 1991 |
Neurotransmitter receptor binding and drug discovery.
Topics: 2-Chloroadenosine; Adenosine; Animals; Barbiturates; Binding, Competitive; Diazepam; gamma-Aminobutyric Acid; Phenylisopropyladenosine; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter; Receptors, Purinergic; Xanthines | 1983 |
486 other study(ies) available for 2-chloroadenosine and adenosine
| Article | Year |
|---|---|
Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists.
Topics: Adenosine; Animals; Body Temperature; Brain; Evoked Potentials; Gerbillinae; In Vitro Techniques; Lipolysis; Male; Mice; Motor Activity; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Solubility; Structure-Activity Relationship; Sulfonic Acids | 1992 |
Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors.
Topics: 2-Chloroadenosine; Animals; Brain; In Vitro Techniques; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1991 |
2-Alkoxyadenosines: potent and selective agonists at the coronary artery A2 adenosine receptor.
Topics: Adenosine; Animals; Atrioventricular Node; Coronary Vessels; Guinea Pigs; Heart; In Vitro Techniques; Models, Molecular; Molecular Conformation; Molecular Structure; Muscle, Smooth, Vascular; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1991 |
C2,N6-disubstituted adenosines: synthesis and structure-activity relationships.
Topics: Adenosine; Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Rats; Receptors, Purinergic; Structure-Activity Relationship | 1989 |
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship | 1995 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.
Topics: Adenine; Adenosine Triphosphate; Anti-Bacterial Agents; Aspartic Acid; Bacteria; Drug Design; Histidine Kinase; HSP90 Heat-Shock Proteins; Models, Molecular; Molecular Docking Simulation; Structure-Activity Relationship | 2017 |
Biological Evaluation of 5'-(
Topics: | 2021 |
Differences in the cation sensitivity of adenylate cyclase from heart and skeletal muscle: modification by guanyl nucleotides and isoproterenol.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Cations, Divalent; Female; Guanine Nucleotides; Guinea Pigs; In Vitro Techniques; Isoproterenol; Magnesium; Manganese; Membranes; Muscles; Myocardium; Sodium Fluoride | 1979 |
Forskolin stimulation of cyclic AMP accumulation in rat brain cortex slices is markedly enhanced by endogenous adenosine.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Drug Synergism; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Purinergic Antagonists; Rats; Rats, Inbred Strains | 1992 |
Influence of benzodiazepines on the response of the guinea-pig isolated trachea to the contractile action of adenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Benzodiazepines; Benzodiazepinones; Epithelium; Guinea Pigs; In Vitro Techniques; Isoquinolines; Male; Muscle Contraction; Phenylisopropyladenosine; Receptors, GABA-A; Trachea | 1992 |
Increased responses to adenosine and 2-chloroadenosine of cyclic AMP-generating systems in the primary cortical region of cobalt-induced epilepsy in the rat.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Cerebral Cortex; Cobalt; Cyclic AMP; Epilepsy; Male; Rats; Rats, Inbred Strains | 1992 |
Adenosine A1-receptor stimulation of inositol phospholipid hydrolysis and calcium mobilisation in DDT1 MF-2 cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Benzoquinones; Calcium; Cell Line; Cricetinae; Hydrolysis; Indomethacin; Lipoxygenase Inhibitors; Male; Muscle, Smooth; Phosphatidylinositols; Receptors, Purinergic | 1992 |
Presynaptic A1-purinoceptor-mediated inhibitory effects of adenosine and its stable analogues on the mouse hemidiaphragm preparation.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diaphragm; Dipyridamole; Electric Stimulation; In Vitro Techniques; Magnesium; Male; Mice; Muscle Contraction; Neuromuscular Junction; Phrenic Nerve; Purinergic Antagonists; Receptors, Purinergic; Synapses; Synaptic Transmission; Theophylline; Tritium; Tubocurarine; Xanthines | 1992 |
A monoclonal anti-idiotypic 'internal image' antibody that recognizes the A1 adenosine receptor potentiates the alpha 1-adrenergic activation of phospholipase C in primary cultures of mouse striatal astrocytes.
Topics: 2-Chloroadenosine; 5,8,11,14-Eicosatetraynoic Acid; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Astrocytes; Cells, Cultured; Corpus Striatum; Enzyme Activation; Female; Mice; Norepinephrine; Pregnancy; Quinacrine; Receptors, Adrenergic, alpha; Receptors, Purinergic; Type C Phospholipases; Xanthines | 1992 |
Calcium currents at motor nerve endings: absence of effects of adenosine receptor agonists in the frog.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Calcium; Calcium Channels; Calcium-Transporting ATPases; In Vitro Techniques; Motor Neurons; Rana pipiens; Receptors, Purinergic | 1992 |
Effect of adenosine analogues and cAMP-raising agents on TNF-, GM-CSF-, and chemotactic peptide-induced degranulation in single adherent neutrophils.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Blood Proteins; Bucladesine; Cell Adhesion; Cell Degranulation; Chemotactic Factors; Colforsin; Cyclic AMP; Cytochalasin B; Exocytosis; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
A1 adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells.
Topics: 2-Chloroadenosine; Adenocarcinoma; Adenosine; Cell Line; Chlorides; Chromosome Deletion; Colonic Neoplasms; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Genotype; Humans; Kinetics; Membrane Proteins; Mutation; Pancreatic Neoplasms; Phenotype; Purinergic Antagonists; Xanthines | 1992 |
Effects of insulin and a tumour promoter, TPA, on glucose transport and metabolism in retinal pigmented epithelium in vitro.
Topics: 2-Chloroadenosine; Adenosine; Animals; Biological Transport; Cell Division; Chick Embryo; Enzyme Activation; Glucose; Insulin; Pigment Epithelium of Eye; Protein Kinase C; Tetradecanoylphorbol Acetate | 1992 |
The ethanol technique of monitoring local blood flow changes in rat skeletal muscle: implications for microdialysis.
Topics: 2-Chloroadenosine; Adenosine; Animals; Blood Glucose; Dialysis; Ethanol; Glycerol; Lactates; Male; Muscles; Perfusion; Rats; Rats, Wistar; Regional Blood Flow | 1992 |
Relative responses to luminal and adventitial adenosine in perfused arteries.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arteries; Biological Transport; Blood Circulation; Dipyridamole; Histological Techniques; In Vitro Techniques; Male; Perfusion; Rabbits; Theophylline | 1992 |
Adenosine-induced hyperpolarization is depressed by glibenclamide in rat CA1 neurones.
Topics: 2-Chloroadenosine; Adenosine; Animals; Glyburide; Hippocampus; In Vitro Techniques; Male; Neurons; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1992 |
Extracellular and intracellular actions of adenosine and related compounds in the reperfused rat intestine.
Topics: 2-Chloroadenosine; Adenosine; Aminoimidazole Carboxamide; Animals; Dipyridamole; Intestines; Male; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reperfusion Injury; Ribonucleosides; Theophylline | 1992 |
Changes in adenosine sensitivity in the hippocampus of rats with streptozotocin-induced diabetes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Biological Transport, Active; Diabetes Mellitus, Experimental; Drug Resistance; Evoked Potentials; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Insulin; Male; Rats; Rats, Inbred Strains | 1992 |
Purinergic agonist induction of metallothionein.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Caffeine; Cells, Cultured; Cladribine; Deoxyadenosines; Dose-Response Relationship, Drug; Immunoblotting; Liver; Male; Metallothionein; Rats; Rats, Inbred Strains; RNA, Messenger; Theophylline; Time Factors; Transcription, Genetic; Vasodilator Agents | 1992 |
Effects of adenosine analogues on ADP ribosylation of GS protein in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate Ribose; Adenosine-5'-(N-ethylcarboxamide); Animals; Blotting, Western; Cattle; Cell Membrane; Cholera Toxin; Coronary Vessels; GTP-Binding Proteins; Guanosine Triphosphate; Isoproterenol; Kinetics; Membrane Proteins; Muscle, Smooth, Vascular; Receptors, Purinergic | 1992 |
Kinetic properties of the common electrophoretic variants of human S-adenosylhomocysteine hydrolase (AHCY): the effect of four nucleoside analogue inhibitors.
Topics: 2-Chloroadenosine; Adenosine; Adenosylhomocysteinase; Anti-Bacterial Agents; Enzyme Inhibitors; Erythrocytes; Humans; Hydrolases; Isomerism; Kinetics; Purine Nucleosides; Ribonucleosides; Tubercidin | 1992 |
Adenosine release in morphine-induced hypotension in rats.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine; Blood Pressure; Dipyridamole; Hypotension; Injections, Intraperitoneal; Injections, Intravenous; Male; Morphine; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Tetrabenazine; Theophylline | 1992 |
Evidence for the presence of A1 and A2 adenosine receptors in the ventral aorta of the dogfish shark, Squalus acanthias.
Topics: 2-Chloroadenosine; Adenosine; Animals; Aorta; Dogfish; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Receptors, Purinergic | 1992 |
Adenosine inhibition of the regeneration in vitro of adult frog sciatic sensory axons.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Imidodiphosphate; Animals; Axons; Cell Division; In Vitro Techniques; Nerve Regeneration; Neurons, Afferent; Rana temporaria; Schwann Cells; Sciatic Nerve; Theophylline; Thymidine | 1992 |
The adenosine receptors present on the plasma membrane of chromaffin cells are of the A2b subtype.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Cell Fractionation; Cell Membrane; Chromaffin System; Phenylisopropyladenosine; Radioligand Assay; Receptors, Purinergic; Tritium; Vasodilator Agents; Xanthines | 1992 |
Elevated extracellular glucose inhibits an adenosine-(Na+,K+)-ATPase regulatory system in rabbit aortic wall.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Aorta, Thoracic; Child, Preschool; Colforsin; Diglycerides; Glucose; Glycerol; Homeostasis; Humans; In Vitro Techniques; Inositol; Male; Muscle, Smooth, Vascular; Phosphatidylinositols; Potassium; Rubidium; Sodium-Potassium-Exchanging ATPase; Theophylline | 1991 |
Inhibition of adenylate cyclase attenuates adenosine receptor-mediated relaxation in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclase Inhibitors; Animals; Colforsin; Coronary Vessels; Cyclic AMP; Dideoxyadenosine; Dilazep; Guanosine Triphosphate; In Vitro Techniques; Muscle Relaxation; Receptors, Purinergic; Sodium Fluoride; Swine; Vasodilator Agents | 1991 |
Adenosine receptors involved in the inhibitory control of non-adrenergic non-cholinergic neurotransmission in guinea-pig atria belong to the A1 subtype.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Atrial Function; Autonomic Nervous System; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Male; Neurons, Afferent; Phenylisopropyladenosine; Receptors, Purinergic; Reserpine; Synaptic Transmission; Theophylline | 1991 |
Analysis of adenosine actions on Ca2+ currents and synaptic transmission in cultured rat hippocampal pyramidal neurones.
Topics: 2-Chloroadenosine; Adenosine; Animals; Calcium; Cells, Cultured; Electrophysiology; Guanosine Triphosphate; Hippocampus; Neurons; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synapses; Synaptic Transmission | 1991 |
Influence of diazepam, alpidem, zolpidem and zopiclone, on the response to adenosine of the guinea pig isolated trachea.
Topics: 2-Chloroadenosine; Adenosine; Animals; Anti-Anxiety Agents; Diazepam; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Hypnotics and Sedatives; Imidazoles; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, GABA-A; Trachea; Zolpidem | 1991 |
Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bucladesine; Cell Survival; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Kinetics; Male; Mice; Mice, Inbred BALB C; Phenylisopropyladenosine; Receptors, Purinergic; T-Lymphocytes | 1990 |
Cold acclimation induces desensitization to adenosine in brown fat cells without changing receptor binding.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Acclimatization; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Cell Membrane; Cells, Cultured; Cold Temperature; Cricetinae; Edetic Acid; Kinetics; Magnesium; Male; Mesocricetus; Norepinephrine; Oxygen Consumption; Phenylisopropyladenosine; Receptors, Purinergic | 1990 |
Inhibition of adenosine responses of rat hippocampal neurones by nifedipine and BAYK 8644.
Topics: 2-Chloroadenosine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Animals; Dihydropyridines; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Neurons; Nifedipine; Pyramidal Tracts; Rats | 1990 |
Dihydropyridines alter adenosine sensitivity in the rat hippocampal slice.
Topics: 2-Chloroadenosine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dihydropyridines; Dipyridamole; Evoked Potentials; Hippocampus; In Vitro Techniques; Magnesium; Male; Nifedipine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Vasodilator Agents | 1990 |
Synergistic regulation of cytosolic Ca2+ concentration in mouse astrocytes by NK1 tachykinin and adenosine agonists.
Topics: 2-Chloroadenosine; 5,8,11,14-Eicosatetraynoic Acid; Adenosine; Animals; Arachidonic Acid; Astrocytes; Calcium; Cells, Cultured; Cytosol; Drug Synergism; Enzyme Activation; Mice; Osmolar Concentration; Protein Kinase C; Receptors, Neurotransmitter; Receptors, Purinergic; Receptors, Tachykinin; Substance P; Tachykinins | 1991 |
Protein kinase C and phospholipase C in adenosine receptor-mediated relaxation in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Alkaloids; Animals; Coronary Vessels; Isoproterenol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroprusside; Phorbol 12,13-Dibutyrate; Potassium Chloride; Protein Kinase C; Receptors, Purinergic; Staurosporine; Swine; Type C Phospholipases | 1991 |
Characterization of the uptake of adenosine by cultured rat hippocampal cells and inhibition of the uptake by xanthine derivatives.
Topics: 2-Chloroadenosine; Adenosine; Affinity Labels; Animals; Biological Transport; Caffeine; Cells, Cultured; Cytarabine; Dipyridamole; Embryo, Mammalian; Hippocampus; Kinetics; Neuroglia; Neurons; Pentoxifylline; Rats; Sodium; Theophylline; Thioinosine; Tritium; Xanthines | 1991 |
Effects of adenosine receptor agonists on volume-activated ion transport in pig red cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane Permeability; Chlorides; Cyclic AMP; Electrolytes; Erythrocytes; Hydrogen; In Vitro Techniques; Potassium; Receptors, Purinergic; Rubidium; Sodium; Swine | 1991 |
Selective protection by adenosine receptor agonists against DMCM-induced seizures.
Topics: 2-Chloroadenosine; Adenosine; Animals; Anticonvulsants; Bicuculline; Carbolines; Convulsants; Female; Mice; Pentylenetetrazole; Phenylisopropyladenosine; Receptors, Purinergic; Seizures; Theophylline | 1991 |
Peripheral mechanisms of thermogenesis induced by ephedrine and caffeine in brown adipose tissue.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature Regulation; Caffeine; Culture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Ephedrine; Male; Oxygen Consumption; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Theophylline; Xanthines | 1991 |
Behavioral effects of intrastriatal caffeine mediated by adenosinergic modulation of dopamine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Behavior, Animal; Caffeine; Corpus Striatum; Dopamine; Flupenthixol; Male; Microinjections; Rats; Rats, Inbred Strains; Rotation; Stereoisomerism; Stereotyped Behavior | 1991 |
Inhibition of Na transport by 2-chloroadenosine: dissociation from production of cyclic nucleotides.
Topics: 2-Chloroadenosine; Adenosine; Animals; Biological Transport; Cell Membrane; Cells, Cultured; Cyclic AMP; Intracellular Fluid; Kidney Medulla; Rats; Rats, Inbred Strains; Sodium; Time Factors | 1990 |
A1 adenosine receptors inhibit chloride transport in the shark rectal gland. Dissociation of inhibition and cyclic AMP.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Chlorides; Colforsin; Cyclic AMP; Dogfish; Female; In Vitro Techniques; Kinetics; Male; Perfusion; Receptors, Purinergic; Salt Gland; Somatostatin; Theophylline | 1990 |
Augmentation of release of gastric somatostatin-like immunoreactivity by adenosine, adenosine triphosphate and their analogs.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Gastric Mucosa; Hexamethonium; Hexamethonium Compounds; Male; Peptides; Perfusion; Rats; Rats, Inbred Strains; Theophylline | 1990 |
Adenosine A2 stimulation of tyrosine hydroxylase in rat striatal minces is reversed by dopamine D2 autoreceptor activation.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Apomorphine; Colforsin; Corpus Striatum; Cyclic AMP; Dopamine Agents; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Purinergic; Theophylline; Tyrosine 3-Monooxygenase | 1990 |
Effects of topical adenosine analogs and forskolin on rat pial arterioles in vivo.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Colforsin; Male; Phenylisopropyladenosine; Pia Mater; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Characterization of the binding of a novel nonxanthine adenosine antagonist radioligand, [3H]CGS 15943, to multiple affinity states of the adenosine A1 receptor in the rat cortex.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Phenylisopropyladenosine; Purinergic Antagonists; Pyrazoles; Quinazolines; Rats; Receptors, Purinergic; Triazoles; Tritium | 1991 |
Effect of MK-801 and its interaction with adenosinergic agents and carbamazepine against hypoxic stress-induced convulsions and death in mice.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbamazepine; Dipyridamole; Dizocilpine Maleate; Drug Interactions; Female; Male; Mice; Seizures; Stress, Physiological; Theophylline | 1990 |
The adhesiveness of monocytic U937 cells is stimulated by pro-inflammatory agents and inhibited by adenosine 3':5'-cyclic monophosphate.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Alprostadil; Bucladesine; Calcitriol; Cell Adhesion; Cell Differentiation; Cell Line; Cyclic AMP; Diglycerides; Humans; Kinetics; Leukotriene B4; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Platelet Activating Factor; Tretinoin | 1990 |
Immune-related intestinal chloride secretion. II. Effect of adenosine on T84 cell line.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Calcium; Cell Line; Chlorides; Cyclic AMP; Cyclic GMP; Cytosol; Electrolytes; Epithelium; Histamine; Humans; Inflammation; Kinetics; Phenylisopropyladenosine; Phosphorylation; Protein Kinases; Theophylline | 1990 |
Direct effects of chronic ethanol exposure on beta-adrenergic and adenosine-sensitive adenylate cyclase activities and cyclic AMP content in primary cerebellar cultures.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Cells, Cultured; Cerebellum; Cyclic AMP; Dose-Response Relationship, Drug; Ethanol; Guanylyl Imidodiphosphate; Isoproterenol; Norepinephrine; Receptors, Adrenergic, beta; Time Factors | 1990 |
Failure of adenosine analogues to affect N-type voltage sensitive Ca2+ channels in chicken brain synaptosomes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Calcium; Calcium Channels; Chickens; Kinetics; omega-Conotoxins; Peptides, Cyclic; Synaptosomes | 1990 |
Regional difference in responsiveness of adenosine-sensitive cyclic AMP-generating systems in chronic epileptic cerebral cortex of the rat.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Cerebral Cortex; Cyclic AMP; Epilepsy; In Vitro Techniques; Male; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
12-O-tetradecanoylphorbol 13-acetate potentiates the action of cAMP in inducing DNA cleavage in thymocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bucladesine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; DNA; Kinetics; Male; Mice; Mice, Inbred BALB C; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1990 |
Adenosine modulates a voltage-dependent chloride conductance in cultured hippocampal neurons.
Topics: 2-Chloroadenosine; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Action Potentials; Adenosine; Animals; Cells, Cultured; Chloride Channels; Chlorides; Electric Conductivity; Hippocampus; Membrane Potentials; Membrane Proteins; Neurons; Phenylisopropyladenosine; Rats; Rats, Inbred Strains | 1990 |
Hemodynamic effects of adenosine agonists in the conscious spontaneously hypertensive rat.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Heart Rate; Hydralazine; Injections, Intravenous; Male; Rats; Rats, Inbred SHR; Receptors, Purinergic; Renin; Vascular Resistance; Vasodilator Agents | 1990 |
Adenosine A2 receptors mediate cerebral vasodilation in the conscious goat.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Goats; Phenylisopropyladenosine; Receptors, Purinergic; Vasodilation; Vasodilator Agents | 1990 |
2-Chloroadenosine decreases long-term potentiation in the hippocampal CA1 area of the rat.
Topics: 2-Chloroadenosine; Adenosine; Animals; Electric Stimulation; Electrodes, Implanted; Hippocampus; In Vitro Techniques; Rats; Rats, Inbred Strains; Synapses; Theophylline | 1990 |
The coexistence of adenosine A1 and A2 receptors in guinea-pig aorta.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Guinea Pigs; Male; Muscle Contraction; Phenylephrine; Phenylisopropyladenosine; Receptors, Purinergic; Vasodilator Agents | 1990 |
A1 adenosinergic modulation alters the duration of maximal dentate activation.
Topics: 2-Chloroadenosine; Adenosine; Animals; Electric Stimulation; Hippocampus; Limbic System; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Seizures; Time Factors; Xanthines | 1990 |
Effects of some adenosine analogs on morphine-induced analgesia and tolerance.
Topics: 2-Chloroadenosine; Adenosine; Analgesics; Animals; Caffeine; Drug Synergism; Drug Tolerance; Injections, Intraventricular; Mice; Morphine; Naloxone; Phenylisopropyladenosine | 1990 |
Relaxation by adenosine and its analogs of potassium-contracted human coronary arteries.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Coronary Vessels; Humans; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylisopropyladenosine; Potassium; Receptors, Purinergic | 1990 |
Inhibition by chlordiazepoxide of adenosine-stimulated glucagon secretion.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Chlordiazepoxide; Glucagon; Isoproterenol; Male; Rats; Rats, Inbred Strains; Vasodilation | 1990 |
Inositol phospholipid hydrolysis in human brain; adenosine inhibition of the response to histamine.
Topics: 2-Chloroadenosine; Adenosine; Adult; Aged; Brain; Carbachol; Female; Histamine; Humans; In Vitro Techniques; Inositol Phosphates; Male; Middle Aged; Norepinephrine; Potassium Chloride; Serotonin; Theophylline | 1990 |
2-Chloroadenosine induction of vagally-mediated and atropine-resistant bronchomotor responses in anaesthetized guinea-pigs.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Anesthesia; Animals; Atropine; Bronchi; Capsaicin; Drug Resistance; Guinea Pigs; Inosine; Male; Muscle Contraction; Muscle, Smooth; Neurons, Afferent; Phenylisopropyladenosine; Receptors, Purinergic; Serotonin; Vagus Nerve | 1990 |
2-Chloro-[3H]-adenosine binding in isolated rat kidney membranes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Binding, Competitive; In Vitro Techniques; Kidney; Rats; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Characteristics of adenosine binding sites in atrial sarcolemmal membranes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Binding, Competitive; Cattle; Endopeptidases; Heart Atria; Myocardium; Sarcolemma; Subcellular Fractions; Theophylline; Time Factors | 1985 |
Adenosine receptors on canine parietal cells modulate gastric acid secretion to histamine.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Dogs; Dose-Response Relationship, Drug; Female; Gastric Acid; Histamine; In Vitro Techniques; Male; Parietal Cells, Gastric; Phenylisopropyladenosine; Prostaglandins; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Effects of pertussis toxin treatment on metabolism in hamster brown adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue, Brown; Animals; Cricetinae; Drug Synergism; Isoproterenol; Lipolysis; Male; Mesocricetus; NAD; Oxygen Consumption; Pertussis Toxin; Phenylephrine; Virulence Factors, Bordetella | 1985 |
Scorpion venom (Leiurus quinquestriatus) elicits accumulations of inositol phosphates and cyclic AMP in guinea pig cortical synaptoneurosomes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cerebral Cortex; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pigs; Inositol Phosphates; Ion Channels; Male; Membrane Potentials; Phosphatidylinositols; Scorpion Venoms; Sugar Phosphates; Synaptosomes; Tetrodotoxin | 1986 |
Regulation of bovine sperm motility and cyclic adenosine 3',5'-monophosphate by adenosine and its analogues.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Bicarbonates; Cattle; Cyclic AMP; Dibucaine; Male; Sperm Motility; Spermatozoa; Structure-Activity Relationship; Theophylline | 1986 |
Accumulations of cyclic AMP and inositol phosphates in guinea pig cerebral cortical synaptoneurosomes: enhancement by agents acting at sodium channels.
Topics: 2-Chloroadenosine; Adenosine; Alkaloids; Animals; Batrachotoxins; Calcium; Cerebral Cortex; Cyclic AMP; Egtazic Acid; Guinea Pigs; Indolizines; Inositol Phosphates; Ion Channels; Male; Norepinephrine; Piperidines; Scorpion Venoms; Sodium; Sugar Phosphates; Synaptosomes; Tetrodotoxin | 1986 |
Adenosine induced immunosuppression: the role of the adenosine receptor--adenylate cyclase interaction in the alteration of T-lymphocyte surface phenotype and immunoregulatory function.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Adult; Antibodies, Monoclonal; Antigens, Surface; B-Lymphocytes; Cell Differentiation; Humans; Immune Tolerance; Isoproterenol; Kinetics; Receptors, Cell Surface; Receptors, Purinergic; T-Lymphocytes; Theophylline | 1986 |
Mucosal adenosine stimulates chloride secretion in canine tracheal epithelium.
Topics: 2-Chloroadenosine; Adenosine; Animals; Chlorides; Cyclic AMP; Dogs; Ion Channels; Mucous Membrane; Receptors, Cell Surface; Receptors, Purinergic; Sodium; Stimulation, Chemical; Theophylline; Trachea | 1986 |
Calcium-dependent currents in cultured rat dorsal root ganglion neurones are inhibited by an adenosine analogue.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Action Potentials; Adenosine; Adenylyl Cyclases; Animals; Baclofen; Calcium; Cells, Cultured; Depression, Chemical; Ganglia, Spinal; Ion Channels; Neurons; Potassium; Rats; Tetraethylammonium; Tetraethylammonium Compounds; Theophylline | 1986 |
Specific inhibition of dopamine D-1-mediated cyclic AMP formation by dopamine D-2, muscarinic cholinergic, and opiate receptor stimulation in rat striatal slices.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adenosine; Alprostadil; Animals; Benzazepines; Carbachol; Cholera Toxin; Corpus Striatum; Cyclic AMP; Isoproterenol; Morphine; Phenethylamines; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Receptors, Opioid; Vasoactive Intestinal Peptide | 1986 |
Adenosine receptors on human basophils and lung mast cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Basophils; Histamine Release; Humans; Immunoglobulin E; Mast Cells; Phenylisopropyladenosine; Receptors, Purinergic | 1986 |
Characteristics of high affinity and low affinity adenosine binding sites in human cerebral cortex.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Membrane; Cerebral Cortex; Humans; Kinetics; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline | 1986 |
ATP release from affinity-purified rat cholinergic nerve terminals.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Triphosphate; Animals; Cholinergic Fibers; Chromatography, High Pressure Liquid; Potassium Chloride; Rats; Sheep; Theophylline; Veratridine | 1987 |
Prostacyclin analogues reduce ADP-ribosylation of the alpha-subunit of the regulatory Gs-protein and diminish adenosine (A2) responsiveness of platelets.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate Ribose; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Adult; Blood Platelets; Epoprostenol; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Iloprost; In Vitro Techniques; Sodium Fluoride; Vasodilator Agents | 1987 |
Red blood cells mediate spontaneous aggregation of platelets in whole blood.
Topics: 2-Chloroadenosine; Adenosine; Adult; Aged; Aspirin; Epoprostenol; Erythrocytes; Humans; Iloprost; In Vitro Techniques; Middle Aged; Platelet Aggregation; Platelet Count; Sulfonamides; Thrombosis | 1987 |
Development of adenosine-dependent cyclic AMP accumulation in the avian optic tectum.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Deaminase; Animals; Chick Embryo; Cyclic AMP; Dipyridamole; Proteins; Superior Colliculi | 1987 |
Nerve growth factor treatment or cAMP elevation reduces Ca2+/calmodulin-dependent protein kinase III activity in PC12 cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adrenal Gland Neoplasms; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Cyclic AMP; Cytosol; Elongation Factor 2 Kinase; Epidermal Growth Factor; Kinetics; Nerve Growth Factors; Pheochromocytoma; Phosphorylation; Protein Kinases | 1987 |
Measurement of antagonist affinity for purine receptors of drugs producing concomitant phosphodiesterase blockade: the use of pharmacologic resultant analysis.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Regression Analysis; Theophylline; Vas Deferens | 1987 |
Purine receptors and kynurenic acid modulate the somatosensory evoked potential in rat cerebral cortex.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; Evoked Potentials, Somatosensory; Kynurenic Acid; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Synaptic Transmission | 1988 |
Neuromodulator-mediated phosphorylation of specific proteins in a neurotumor hybrid cell line (NCB-20).
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Alprostadil; Animals; Brain; Calcimycin; Colforsin; Cricetinae; Cyclic AMP; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Hybrid Cells; Immunoassay; Mice; Nerve Tissue Proteins; Neuroblastoma; Neurotransmitter Agents; Phosphoproteins; Phosphorylation; Protein Kinases; Serotonin; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1988 |
On the adenosine receptor and adenosine inactivation at the rat diaphragm neuromuscular junction.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Diaphragm; Evoked Potentials; Female; In Vitro Techniques; Male; Motor Endplate; Muscle Contraction; Neuromuscular Junction; Rats; Rats, Inbred Strains; Receptors, Purinergic; Temperature; Theophylline | 1988 |
Studies on the ionic mechanism for the neuromodulatory actions of adenosine in the brain.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Calcium; Male; Neurotransmitter Agents; Potassium; Potassium Channels; Rats; Rats, Inbred Strains; Synaptic Membranes; Synaptosomes; Thiocyanates; Valinomycin; Veratridine | 1988 |
Inhibition by adenosine of histamine and leukotriene release from human basophils.
Topics: 2-Chloroadenosine; Adenosine; Basophils; Coformycin; Histamine Release; Humans; In Vitro Techniques; Pentostatin; SRS-A; Structure-Activity Relationship; Theophylline | 1989 |
Human basophil/mast cell releasability. VII. Heterogeneity of the effect of adenosine on mediator secretion.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Basophils; Histamine Release; Humans; Immunoglobulin E; Lung; Mast Cells; Phenylisopropyladenosine; Prostaglandin D2; Skin; SRS-A; Vasodilator Agents | 1989 |
Development of pharmacological sensitivity to adenosine analogs in embryonic chick heart: role of A1 adenosine receptors and adenylyl cyclase inhibition.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclase Inhibitors; Animals; Chick Embryo; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart Rate; Potassium Channels; Receptors, Muscarinic; Receptors, Purinergic | 1989 |
Adenosine receptor-mediated relaxation in coronary artery: evidence for a guanyl nucleotide-binding regulatory protein involvement.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Cholera Toxin; Colforsin; Coronary Vessels; Ethylmaleimide; GTP-Binding Proteins; In Vitro Techniques; Receptors, Purinergic; Theophylline; Vasodilation | 1989 |
A cerebral vasoconstrictive effect of some adenosine analogues. A study of adenosine analogues on local cerebral blood flow and glucose utilisation in the rat.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autoradiography; Brain; Carotid Artery, Internal; Cerebrovascular Circulation; Deoxyglucose; Glucose; Male; Rats; Rats, Inbred Strains; Rheology; Vasoconstrictor Agents | 1989 |
Glucocorticoid administration increases receptor-mediated and forskolin-stimulated cyclic AMP accumulation in rat brain cerebral cortical slices.
Topics: 2-Chloroadenosine; Adenosine; Adrenocorticotropic Hormone; Animals; Cerebral Cortex; Colforsin; Cyclic AMP; Dexamethasone; In Vitro Techniques; Isoproterenol; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Reference Values; Sodium Fluoride; Vasoactive Intestinal Peptide | 1989 |
Aluminum increases agonist-stimulated cyclic AMP production in rat cerebral cortical slices.
Topics: 2-Chloroadenosine; Adenosine; Aluminum; Aluminum Chloride; Aluminum Compounds; Animals; Cerebral Cortex; Chlorides; Colforsin; Cyclic AMP; Isoproterenol; Male; Osmolar Concentration; Rats; Solutions; Stimulation, Chemical; Time Factors | 1989 |
Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors.
Topics: 2-Chloroadenosine; Adenosine; Alprazolam; Anxiety; Caffeine; Chlordiazepoxide; Clonidine; Flumazenil; Motor Activity; Muscle Relaxants, Central; Norepinephrine; Propranolol; Receptors, Adrenergic; Receptors, GABA-A; Receptors, Purinergic; Social Behavior | 1989 |
Macrophage activation and host augmentation against Sendai or herpes simplex virus (HSV) infections with synthetic polypeptides in mice.
Topics: 2-Chloroadenosine; Adenosine; Administration, Intranasal; Animals; Female; Herpes Simplex; Immune Tolerance; Injections, Intraperitoneal; Injections, Intravenous; Interferons; Lung; Macrophage Activation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Paramyxoviridae Infections; Peptides; Time Factors | 1989 |
Modulation of Ca-channel current by an adenosine analog mediated by a GTP-binding protein in chick sensory neurons.
Topics: 2-Chloroadenosine; Adenosine; Animals; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Electrophysiology; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Mollusk Venoms; Neurons, Afferent; omega-Conotoxins; Second Messenger Systems; Thionucleotides | 1989 |
Effect of magnesium on depression of the monosynaptic reflex induced by 2-chloroadenosine or hypoxia in the isolated spinal cord of neonatal rats.
Topics: 2-Chloroadenosine; Adenosine; Animals; Depression, Chemical; Electrophysiology; Kinetics; Magnesium; Oxygen; Rats; Reflex, Monosynaptic; Spinal Cord; Synaptic Transmission | 1989 |
Effect of adenosine and adenosine analogs on [14C]aminopyrine accumulation by rabbit parietal cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Aminopyrine; Animals; Carbon Radioisotopes; Cyclic AMP; Gastric Acid; Male; Parietal Cells, Gastric; Rabbits; Receptors, Purinergic | 1989 |
Asthmatic patients have neutrophils that exhibit diminished responsiveness to adenosine.
Topics: 2-Chloroadenosine; Adenosine; Asthma; Calcimycin; Cytochalasin B; Dinoprostone; Dose-Response Relationship, Drug; Humans; Isoproterenol; Lipopolysaccharides; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Superoxides | 1989 |
Pharmacological and functional heterogeneity of astrocytes: regional differences in phospholipase C stimulation by neuromediators.
Topics: 2-Chloroadenosine; Adenosine; Animals; Astrocytes; Brain; Carbachol; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Drug Synergism; Embryo, Mammalian; Mesencephalon; Mice; Neurotransmitter Agents; Norepinephrine; Type C Phospholipases | 1989 |
Expression of A1 adenosine receptors modulating dopamine-dependent cyclic AMP accumulation in the chick embryo retina.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Apomorphine; Chick Embryo; Cyclic AMP; Dopamine; Dose-Response Relationship, Drug; Receptors, Cell Surface; Receptors, Purinergic; Retina | 1985 |
Adenosine as putative regulator of hepatic arterial flow (the buffer response).
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Blood Pressure; Cats; Dipyridamole; Hepatic Artery; Liver Circulation; Portal System; Rheology; Time Factors; Vasodilation | 1985 |
Mechanism of action and selective toxicity of ascamycin, a nucleoside antibiotic.
Topics: 2-Chloroadenosine; Adenosine; Alanine; Anti-Bacterial Agents; Bacteria; Bacterial Proteins; DNA, Bacterial; Escherichia coli; Microbial Sensitivity Tests; Peptide Biosynthesis; Peptides; Poly U; RNA, Bacterial; Xanthomonas | 1985 |
Adenosine inhibition of catecholamine-stimulated cardiac membrane adenylate cyclase.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Animals; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Male; Myocardium; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Sodium Fluoride | 1985 |
Effects of adenosine analogs and ouabain on rhythmicity in human coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adolescent; Adult; Child; Coronary Vessels; Dinoprost; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Potassium | 1989 |
Evidence for adenosine receptor-mediated hyperpolarization in coronary smooth muscle.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Coronary Vessels; Electrophysiology; Membrane Potentials; Muscle, Smooth, Vascular; Potassium Chloride; Receptors, Purinergic; Theophylline; Vasodilator Agents | 1989 |
Adenosine A1 receptor activation mediates suppression of (-) bicuculline methiodide-induced seizures in rat prepiriform cortex.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autoradiography; Bicuculline; Cerebral Cortex; Dose-Response Relationship, Drug; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Seizures | 1989 |
Relationship between extracellular and intracellular nucleotide metabolism in human lymphocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; B-Lymphocytes; Dose-Response Relationship, Drug; Extracellular Space; Humans; Inosine; Purines; T-Lymphocytes | 1989 |
Effect of adenosine on melatonin and norepinephrine release in rat pineal explants.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Analysis of Variance; Animals; Male; Melatonin; Norepinephrine; Periodicity; Pineal Gland; Rats; Tissue Extracts | 1989 |
Microdialysis of intercellular adenosine concentration in subcutaneous tissue in humans.
Topics: 2-Chloroadenosine; Adenosine; Adipose Tissue; Adult; Biological Transport, Active; Dialysis; Glucose; Humans; Insulin; Lipolysis; Male; Norepinephrine; Reference Values | 1989 |
A neuroglial cooperativity is required for the potentiation by 2-chloroadenosine of the muscarinic-sensitive phospholipase C in the striatum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Carbachol; Cells, Cultured; Corpus Striatum; Cytological Techniques; Drug Synergism; In Vitro Techniques; Inositol Phosphates; Muscarine; Neuroglia; Neurons; Norepinephrine; Receptors, Purinergic; Type C Phospholipases | 1989 |
The adenosine agonist N6-R-phenylisopropyladenosine (R-PIA) stimulates feeding in rats.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Feeding Behavior; Grooming; Male; Motor Activity; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Laser-Doppler assessment of brain microcirculation: effect of local alterations.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bradykinin; Brain; Cerebral Arteries; Cerebrovascular Circulation; Lasers; Male; Microcirculation; Rabbits; Regional Blood Flow; Vasodilation | 1989 |
Transduction mechanism involving the presynaptic adenosine receptor at mouse motor nerve terminals.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Chloroadenosine; Adenosine; Animals; Enzyme Inhibitors; Isoquinolines; Membrane Potentials; Mice; Motor Endplate; Motor Neurons; Neuromuscular Junction; Pertussis Toxin; Piperazines; Protein Kinases; Receptors, Purinergic; Signal Transduction; Virulence Factors, Bordetella | 1989 |
An unusual receptor mediates adenosine-induced SA nodal bradycardia in dogs.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Atrial Function; Dipyridamole; Dogs; Heart Atria; Heart Rate; Kinetics; Receptors, Purinergic; Reference Values; Sinoatrial Node; Structure-Activity Relationship | 1989 |
The effect of local infusion of adenosine and adenosine analogues on local cerebral blood flow.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebrovascular Circulation; Dialysis; Injections, Intraventricular; Perfusion; Rats; Rats, Inbred Strains; Theophylline | 1989 |
Adenosine regulates the respiratory burst of cytokine-triggered human neutrophils adherent to biologic surfaces.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Cell Adhesion; Cell Aggregation; Humans; Immunosuppressive Agents; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen Consumption; Tumor Necrosis Factor-alpha | 1989 |
Adenosine analogs inhibit gastric acid secretion.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Gastric Mucosa; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Stereoisomerism | 1989 |
Vessel reactivity and prejunctional modulatory changes in the portal vein of mature spontaneously hypertensive rats.
Topics: 2-Chloroadenosine; Adenosine; Aging; Animals; Blood Vessels; Electric Stimulation; Hypertension; In Vitro Techniques; Norepinephrine; Portal Vein; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Purinergic; Sympathetic Nervous System | 1989 |
Identification of adenosine receptor in rat pineal gland: evidence for A-2 selectivity.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cell Membrane; Ethylmaleimide; Guanylyl Imidodiphosphate; Male; Phenylisopropyladenosine; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, Purinergic; S-Adenosylhomocysteine | 1989 |
Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvaria.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Bone and Bones; Bone Resorption; Cells, Cultured; Colforsin; Cyclic AMP; Mice; Phenylisopropyladenosine; Pyrrolidinones; Receptors, Cyclic AMP; Rolipram; Theophylline | 1987 |
Adenosine receptor-mediated effects by nonmetabolizable adenosine analogs in preovulatory rat granulosa cells: a putative local regulatory role of adenosine in the ovary.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Female; Follicle Stimulating Hormone; Granulosa Cells; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic | 1988 |
Cyclic AMP concentrations modulate both calcium flux and hydrolysis of phosphatidylinositol phosphates in mouse T lymphocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Calcium; Calcium Channel Blockers; Cholera Toxin; Colforsin; Cyclic AMP; Dinoprostone; Hydrolysis; Kinetics; Male; Mice; Mice, Inbred Strains; Phosphatidylinositols; Phosphorylation; Prostaglandins E; T-Lymphocytes | 1988 |
Influence of rolipram on the cyclic 3',5'-adenosine monophosphate response to histamine and adenosine in slices of guinea-pig cerebral cortex.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cerebral Cortex; Cyclic AMP; Female; Guinea Pigs; Histamine; In Vitro Techniques; Kinetics; Male; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram | 1988 |
Adenosine inhibits choline kinase activity and decreases the phosphorylation of choline in striatal synaptosomes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Choline; Choline Kinase; Corpus Striatum; Deoxyadenosines; Dideoxyadenosine; Kinetics; Male; Phosphorylation; Phosphorylcholine; Phosphotransferases; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |
Role of adenosine in noradrenergic neurotransmission.
Topics: 2-Chloroadenosine; Adenosine; Animals; Blood Pressure; Electric Stimulation; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reference Values; Regional Blood Flow; Splanchnic Circulation; Sympathetic Nervous System; Synaptic Transmission; Xanthines | 1988 |
Differential response of adenylate cyclase and ATPase activities after chronic ethanol exposure of PC12 cells.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Adrenal Gland Neoplasms; Ca(2+) Mg(2+)-ATPase; Chlorides; Enzyme Activation; Ethanol; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Manganese; Manganese Compounds; Neurons; Ouabain; Pheochromocytoma; Sodium Fluoride; Sodium-Potassium-Exchanging ATPase; Tumor Cells, Cultured | 1988 |
A novel bioaction of PAF: induction of microbicidal activity in guinea pig bone marrow cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bone Marrow; Bone Marrow Cells; Candida; Carrageenan; Cells, Cultured; Guinea Pigs; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled | 1988 |
The regulation of noradrenaline synthesis in central nerve terminals by autoreceptors and heteroreceptors in rat.
Topics: 2-Chloroadenosine; Adenosine; Animals; Clonidine; Enzyme Activation; Hippocampus; In Vitro Techniques; Male; Norepinephrine; Potassium; Rats; Receptors, Adrenergic, alpha; Receptors, GABA-A; Synaptosomes; Tyrosine 3-Monooxygenase | 1985 |
Effects of insulin, adenosine, and prostaglandin on alpha-adrenergic-stimulated respiration in brown adipocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue, Brown; Adrenergic alpha-Agonists; Animals; Cricetinae; Dinoprostone; Insulin; Isoproterenol; Mesocricetus; Oxygen Consumption; Pertussis Toxin; Phenylephrine; Prostaglandins E; Virulence Factors, Bordetella | 1986 |
Maintenance of murine oocyte meiotic arrest: uptake and metabolism of hypoxanthine and adenosine by cumulus cell-enclosed and denuded oocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Biological Transport; Hypoxanthines; IMP Dehydrogenase; Inosine; Meiosis; Mice; Mycophenolic Acid; Oocytes; Ribonucleosides | 1986 |
Investigation of dopamine content, synthesis, and release in the rabbit retina in vitro: II. Effects of high potassium, adenylate cyclase activators, and N-n-propyl-3-(3-hydroxyphenyl) piperidine.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Calcium; Colforsin; Dopamine; Enzyme Activation; Female; Male; Piperidines; Potassium; Rabbits; Retina; Tyrosine 3-Monooxygenase; Vasoactive Intestinal Peptide | 1986 |
Phorbol esters enhance neurotransmitter-stimulated cyclic AMP production in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Colforsin; Cyclic AMP; Dinoprostone; Drug Synergism; Isoproterenol; Male; Molecular Weight; Neurotransmitter Agents; Phorbol Esters; Phosphorylation; Prostaglandins E; Protein Kinase C; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate; Tissue Distribution; Vasoactive Intestinal Peptide | 1986 |
Substance B: an endogenous brain factor that reverses presynaptic inhibition of acetylcholine release.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Brain Chemistry; Dimethylphenylpiperazinium Iodide; Guinea Pigs; In Vitro Techniques; Neurotransmitter Agents; Phenylisopropyladenosine; Receptors, Neurotransmitter | 1986 |
Effects of glutaminase inhibition on release of endogenous glutamic acid.
Topics: 2-Chloroadenosine; Adenosine; Amygdala; Animals; Aspartic Acid; Diazooxonorleucine; Dopamine; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glutaminase; Glycine; Haloperidol; In Vitro Techniques; Rats; Serotonin; Synaptosomes | 1986 |
Morphine tolerance and nonspecific subsensitivity of the longitudinal muscle myenteric plexus preparation of the guinea-pig to inhibitory agonists.
Topics: 2-Chloroadenosine; Adenosine; Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Guinea Pigs; Ileum; Male; Morphine; Muscle, Smooth; Myenteric Plexus; Xylazine | 1988 |
Adenosine and dopamine simultaneously determined in urine by reversed-phase HPLC, with on-line measurement of ultraviolet absorbance and electrochemical detection.
Topics: 2-Chloroadenosine; Adenosine; Adult; Boronic Acids; Chromatography, High Pressure Liquid; Dopamine; Female; Humans; Hydrochloric Acid; Isoproterenol; Male; Methanol; Middle Aged; Quality Control; Reference Values | 1989 |
Characteristics of an adenosine A1 binding site in human placental membranes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Membrane; Female; Guanine Nucleotides; Guanylyl Imidodiphosphate; Humans; Kinetics; Placenta; Pregnancy; Receptors, Purinergic | 1989 |
1,3,8- and 1,3,7-substituted xanthines: relative potency as adenosine receptor antagonists at the frog neuromuscular junction.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bronchodilator Agents; Neuromuscular Junction; Rana ridibunda; Receptors, Purinergic; Xanthines | 1989 |
A1 and A2 adenosine receptor activation inhibits and stimulates renin secretion of rat renal cortical slices.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Egtazic Acid; Gallopamil; In Vitro Techniques; Kidney Cortex; Male; Ouabain; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Renin; Theophylline; Vanadates; Vanadium | 1985 |
Hypothermia-induced supersensitivity to adenosine for responses mediated via A1-receptors but not A2-receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbachol; Female; Guinea Pigs; Heart; Hypothermia; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myocardial Contraction; Rats; Receptors, Cell Surface; Receptors, Purinergic; Trachea; Vas Deferens | 1985 |
Novel adenosine receptors in rat hippocampus. Identification and characterization.
Topics: 2-Chloroadenosine; Adenosine; Allosteric Site; Animals; Binding, Competitive; Brain; Hippocampus; Kinetics; Radioligand Assay; Rats; Receptors, Cell Surface; Receptors, Purinergic; Xanthines | 1985 |
Characterization of pre- and post-junctional adenosine receptors in guinea-pig ileum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cholinergic Fibers; Colforsin; Cyclic AMP; Diterpenes; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Phenylisopropyladenosine; Pyrrolidinones; Receptors, Cell Surface; Receptors, Neurotransmitter; Receptors, Purinergic; Rolipram; Synaptic Transmission | 1985 |
Muscle relaxant action of 2-chloroadenosine in genetically spastic rats is independent of gamma-aminobutyric acid-mediated inhibition.
Topics: 2-Chloroadenosine; Adenosine; Animals; Drug Interactions; Female; Male; Muscle Relaxants, Central; Muscle Spasticity; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1985 |
Interactive effects of caffeine, 2-chloroadenosine and haloperidol on activity, social investigation and play fighting of juvenile rats.
Topics: 2-Chloroadenosine; Adenosine; Aggression; Animals; Caffeine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Humans; Male; Motor Activity; Rats; Receptors, Cell Surface; Receptors, Purinergic; Social Behavior | 1985 |
An activator of protein kinase C (phorbol-12-myristate-13-acetate) augments 2-chloroadenosine-elicited accumulation of cyclic AMP in guinea pig cerebral cortical particulate preparations.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cell-Free System; Cerebral Cortex; Cyclic AMP; Drug Synergism; Enzyme Activation; Guinea Pigs; Inositol Phosphates; Male; Phorbols; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate | 1985 |
On the type of receptor involved in the inhibitory action of adenosine at the neuromuscular junction.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; In Vitro Techniques; Neuromuscular Junction; Phenylisopropyladenosine; Rana ridibunda; Receptors, Cell Surface; Receptors, Purinergic; Synaptic Transmission; Theophylline | 1985 |
Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Binding Sites; Binding, Competitive; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Cell Surface; Receptors, Purinergic; Superoxides; Theophylline | 1985 |
Adenosine analogues stimulate cyclic AMP formation in rabbit cerebral microvessels via adenosine A2-receptors.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cats; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; Microcirculation; Phenylisopropyladenosine; Pyrrolidinones; Rabbits; Receptors, Cell Surface; Receptors, Purinergic; Rolipram | 1985 |
Effects of adenosine analogs on glucagon-stimulated adenosine 3',5'-monophosphate formation in Sertoli cell cultures from immature rats.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cells, Cultured; Cyclic AMP; Follicle Stimulating Hormone; Glucagon; Kinetics; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Sertoli Cells; Sexual Maturation | 1985 |
Biochemical characterization of a filtered synaptoneurosome preparation from guinea pig cerebral cortex: cyclic adenosine 3':5'-monophosphate-generating systems, receptors, and enzymes.
Topics: 2-Chloroadenosine; 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholinesterase; Adenosine; Adenylyl Cyclases; Animals; Butyrylcholinesterase; Cerebral Cortex; Colforsin; Cyclic AMP; Diterpenes; Dose-Response Relationship, Drug; Filtration; Guinea Pigs; Histamine; Microscopy, Electron; Norepinephrine; Receptors, Adrenergic, beta; Receptors, Cell Surface; Receptors, Histamine H2; Receptors, Purinergic; Synaptosomes | 1985 |
Adenosine-activated potassium conductance in cultured striatal neurons.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Cell Membrane; Cells, Cultured; Corpus Striatum; Electric Conductivity; Evoked Potentials; Mice; Neurons; Potassium; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1985 |
Purine nucleoside--mediated immobility in mice: reversal by antidepressants.
Topics: 2-Chloroadenosine; Adenosine; Adrenergic Fibers; Animals; Antidepressive Agents; Depressive Disorder; Disease Models, Animal; Female; Humans; Male; Mice; Receptors, Neurotransmitter; Receptors, Purinergic | 1985 |
Adenosine stimulates sodium transport in kidney A6 epithelia in culture.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; Biological Transport, Active; Cell Line; Cyclic AMP; Epithelium; Kidney; Kinetics; Sodium; Theobromine; Xenopus | 1985 |
Characteristics of high-affinity and low-affinity adenosine binding sites in human cerebral cortex.
Topics: 2-Chloroadenosine; Adenosine; Binding, Competitive; Cell Membrane; Cerebral Cortex; Humans; Kinetics; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship | 1985 |
Accumulation of inositol phosphates and cyclic AMP in guinea-pig cerebral cortical preparations. Effects of norepinephrine, histamine, carbamylcholine and 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbachol; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Histamine; Inositol; Inositol Phosphates; Kinetics; Male; Metiamide; Norepinephrine; Prazosin; Propranolol; Pyrilamine; Serotonin; Sugar Phosphates; Tritium | 1985 |
Vasopressin inhibition of cyclic AMP accumulation and effects on the learned response in inbred mouse strains.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine Vasopressin; Avoidance Learning; Cerebral Cortex; Colforsin; Conditioning, Psychological; Cyclic AMP; Mice; Mice, Inbred Strains; Norepinephrine; Species Specificity | 1985 |
Cobalt ion enhancement of 2-chloro[3H]adenosine binding to a novel class of adenosine receptors in brain: antagonism by calcium.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Calcium; Cobalt; Edetic Acid; Lanthanum; Rats; Receptors, Cell Surface; Receptors, Neurotransmitter; Receptors, Purinergic | 1985 |
Dual effects of adenosine and adenosine analogues on motor activity of the human fallopian tube.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Fallopian Tubes; Female; Humans; Lidocaine; Menstruation; Middle Aged; Muscle Contraction; Muscle, Smooth; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1985 |
The protein kinase C activator phorbol-12-myristate-13-acetate enhances cyclic AMP accumulation in pheochromocytoma cells.
Topics: 2-Chloroadenosine; Adenosine; Adrenal Gland Neoplasms; Animals; Cell Line; Colforsin; Cyclic AMP; Enzyme Activation; Pheochromocytoma; Phorbols; Phosphatidylinositols; Protein Kinase C; Rats; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
A new class of adenosine receptors in brain. Characterization by 2-chloro[3H]adenosine binding.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Binding, Competitive; Brain; Brain Mapping; Ethylmaleimide; Hydrogen-Ion Concentration; Kinetics; Rats; Receptors, Cell Surface; Receptors, Purinergic; Subcellular Fractions; Synaptic Membranes; Temperature | 1986 |
Accumulations of inositol phosphates and cyclic AMP in brain slices: synergistic interactions of histamine and 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbachol; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Histamine; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Receptors, Cell Surface; Receptors, Purinergic; Sugar Phosphates; Theophylline | 1986 |
The effect of presynaptic receptor stimulation on adenosine 3',5'-cyclic monophosphate concentrations in rat cortical synaptosomes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Baclofen; Cerebral Cortex; Clonidine; Cyclic AMP; gamma-Aminobutyric Acid; Male; Norepinephrine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Synaptosomes | 1986 |
Pertussis toxin does not prevent alpha adrenergic stimulated breakdown of phosphoinositides or respiration in brown adipocytes.
Topics: 2-Chloroadenosine; Adenosine; Adipose Tissue, Brown; Animals; Cricetinae; GTP-Binding Proteins; Isoproterenol; Male; Mesocricetus; Oxygen Consumption; Pertussis Toxin; Phenylephrine; Phosphatidylinositols; Propranolol; Receptors, Adrenergic, alpha; Virulence Factors, Bordetella | 1986 |
Characterization of the A2 adenosine receptor labeled by [3H]NECA in rat striatal membranes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Animals; Corpus Striatum; Cyclic AMP; Ethylmaleimide; Female; Fibroblasts; Humans; Male; Mathematics; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Structure-Activity Relationship; Tissue Distribution | 1986 |
Effect of adenosine receptor agonists and other compounds on cyclic AMP accumulation in forskolin-treated hippocampal slices.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Colforsin; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Hippocampus; Histamine; Isoproterenol; Male; Phenylisopropyladenosine; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Xanthines | 1986 |
Evidence against functional adenosine receptors on murine lymphocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Male; Mice; Mitogens; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1986 |
An investigation of the low intrinsic activity of adenosine and its analogs at low affinity (A2) adenosine receptors in rat cerebral cortex.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; Cyclic AMP; Dipyridamole; Guanosine Triphosphate; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Xanthines | 1986 |
Classification of adenosine receptors mediating antinociception in the rat spinal cord.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dose-Response Relationship, Drug; Male; Pain; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Spinal Cord; Theophylline | 1986 |
Purinergic modulation of the seizure threshold for pentylenetetrazol in the rat.
Topics: 2-Chloroadenosine; Adenosine; Animals; Kinetics; Male; Pentylenetetrazole; Phenylisopropyladenosine; Purines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Seizures; Theophylline | 1985 |
Adenosine receptors on human T lymphocytes and human thymocytes.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adult; Child, Preschool; Coformycin; Cyclic AMP; Humans; In Vitro Techniques; Receptors, Purinergic; T-Lymphocytes; Thymus Gland | 1986 |
Superoxide generation by pig alveolar macrophages.
Topics: 2-Chloroadenosine; Adenosine; Animals; Kinetics; Macrophages; Superoxides; Swine | 1986 |
A procedure for measuring alpha 2-adrenergic receptor-mediated inhibition of cyclic AMP accumulation in rat brain slices.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Brimonidine Tartrate; Colforsin; Cyclic AMP; In Vitro Techniques; Isoproterenol; Male; Mianserin; Norepinephrine; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoactive Intestinal Peptide | 1986 |
Qualitative differences in the effects of adenosine analogs on the cholinergic systems of rat striatum and hippocampus.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Corpus Striatum; Female; Glutamates; Hippocampus; In Vitro Techniques; Parasympathetic Nervous System; Parasympathomimetics; Phenylisopropyladenosine; Rats; Synaptic Transmission; Theophylline | 1986 |
Stimulation of phosphoinositide metabolism in hamster brown adipocytes exposed to alpha 1-adrenergic agents and its inhibition with phorbol esters.
Topics: 2-Chloroadenosine; Adenosine; Adipose Tissue, Brown; Animals; Cricetinae; In Vitro Techniques; Insulin; Isoproterenol; Male; Mesocricetus; Oxygen Consumption; Phenylephrine; Phosphatidylinositols; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1986 |
The inhibitory effects of some adenosine analogues on transmitter release at the mammalian neuromuscular junction.
Topics: 2-Chloroadenosine; Adenosine; Animals; In Vitro Techniques; Membrane Potentials; Mice; Neuromuscular Junction; Receptors, Purinergic; Synaptic Transmission; Theophylline | 1986 |
Engagement of adenosine receptors inhibits hydrogen peroxide (H2O2-) release by activated human neutrophils.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Antigen-Antibody Complex; Concanavalin A; Hydrogen Peroxide; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic; Superoxides; Tetradecanoylphorbol Acetate; Zymosan | 1987 |
Phorbol-12,13-dibutyrate enhances the cyclic AMP accumulation in rat hippocampal slices induced by adenosine analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate Ribose; Adenosine-5'-(N-ethylcarboxamide); Adenylate Cyclase Toxin; Animals; Colforsin; Cyclic AMP; Hippocampus; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxants, Central; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Rats, Inbred Strains; Vasodilator Agents; Virulence Factors, Bordetella | 1987 |
Functional evidence for adenosine A2 receptor regulation of phosphatidylcholine secretion in cultured type II pneumocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cyclic AMP; Male; Phenylisopropyladenosine; Phosphatidylcholines; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Receptors, Purinergic; Terbutaline; Theophylline | 1987 |
Central versus peripheral mediation of responses to adenosine receptor agonists: evidence against a central mode of action.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Hippocampus; Injections, Intraperitoneal; Injections, Spinal; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1987 |
Adenosine receptors on rabbit alveolar macrophages: binding characteristics and effects on cellular function.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cell Membrane; Coagulants; Cyclic AMP; Macrophages; Male; Phenylisopropyladenosine; Plasminogen Activators; Rabbits; Receptors, Cell Surface; Time Factors | 1987 |
Inhibition of the shake response in rats by adenosine and 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Behavior, Animal; Cold Temperature; Dose-Response Relationship, Drug; Male; Morphine; Muscle Relaxants, Central; Rats; Shivering; Substance Withdrawal Syndrome | 1986 |
Regulation of sodium absorption by canine tracheal epithelium.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Aldosterone; Amiloride; Animals; Calcimycin; Cattle; Electric Conductivity; Epithelium; In Vitro Techniques; Indomethacin; Isoproterenol; Prostaglandins E; Sodium; Trachea; Water-Electrolyte Balance | 1987 |
Effects of adenosine on sympathetic vasoconstriction in dog gracilis muscle.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dogs; Hemodynamics; Hydralazine; Male; Muscles; Nitroglycerin; Sympathetic Nervous System; Vasoconstriction | 1987 |
In vivo antitumor effect of lymphokine-activated rodent polymorphonuclear leukocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cells, Cultured; Female; Fibrosarcoma; Lymphokines; Male; Mast-Cell Sarcoma; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neutrophils; Picibanil; Rats; Rats, Inbred Strains; T-Lymphocytes, Cytotoxic | 1987 |
Effect of metabolic products of muscular contraction on discharge of group III and IV afferents.
Topics: 2-Chloroadenosine; Adenosine; Afferent Pathways; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cats; Electric Stimulation; Indomethacin; Kinetics; Lactates; Lactic Acid; Muscle Contraction; Muscles; Nerve Fibers; Phosphates; Reference Values | 1988 |
Inhibition of experimental metastasis with indomethacin: role of macrophages and natural killer cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carrageenan; Cytotoxicity, Immunologic; Dinoprostone; Female; G(M1) Ganglioside; Glycosphingolipids; Immune Sera; Indomethacin; Killer Cells, Natural; Lung Neoplasms; Macrophages; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Prostaglandins E; Tumor Cells, Cultured | 1988 |
Involvement of adenosine in synaptic depression induced by a brief period of hypoxia in isolated spinal cord of neonatal rat.
Topics: 2-Chloroadenosine; Adenosine; Animals; Animals, Newborn; In Vitro Techniques; Oxygen; Rats; Reflex, Monosynaptic; Spinal Cord; Time Factors | 1988 |
Characterization of prejunctional purinoceptors on adrenergic nerves of the rat caudal artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Arteries; Azides; Electric Stimulation; Male; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Purinergic; Sympathetic Nervous System; Theophylline | 1988 |
Interactions of adenosine and magnesium on rat hippocampal slices.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Drug Interactions; Electric Stimulation; Hippocampus; In Vitro Techniques; Magnesium; Rats; Theophylline | 1988 |
Pharmacological classification of receptors for adenyl purines in guinea pig myometrium.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Azides; Female; Guanosine; Guinea Pigs; Myometrium; Phenylisopropyladenosine; Receptors, Purinergic; Stereoisomerism; Theophylline; Thionucleosides | 1988 |
Adenosine and ATP: presynaptic effects at the cholinergic nerve terminal.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Triphosphate; Adenylyl Cyclases; Animals; Colforsin; Corpus Striatum; Receptors, Purinergic; Synaptosomes | 1988 |
2-Chloroadenosine prevents kainic acid-induced toxicity in rat striatum.
Topics: 2-Chloroadenosine; Adenosine; Animals; Corpus Striatum; Kainic Acid; Male; Muscle Relaxants, Central; Rats; Rats, Inbred Strains | 1988 |
The influence of 2-chloroadenosine on potassium-evoked and neurally-evoked acetylcholine secretion from normal or from latent active zones in the frog.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Calcium; Electrophysiology; In Vitro Techniques; Magnesium; Neurons; Potassium; Rana pipiens | 1988 |
Melatonin production in organ cultured chicken pineal: modulation by adenosine and its analogs.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Chickens; Colforsin; Deoxyadenosines; Dipyridamole; Melatonin; Organ Culture Techniques; Phenylisopropyladenosine; Pineal Gland; Thioinosine | 1988 |
Adenosine handling in interstitia of cremaster muscle studied by bioassay.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arterioles; Biological Assay; Cricetinae; Diffusion; Dipyridamole; Extracellular Space; Kinetics; Methods; Muscles; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Thioinosine; Vasodilation | 1988 |
Interactions of carbamazepine, chlormethiazole and pentobarbitone with adenosine on hippocampal slices.
Topics: 2-Chloroadenosine; Adenosine; Amino Acids; Animals; Carbamazepine; Chlormethiazole; Hippocampus; In Vitro Techniques; Iontophoresis; Kynurenic Acid; Male; Muscle Relaxants, Central; Pentobarbital; Rats; Receptors, Purinergic; Synapses | 1988 |
Influence of 2-chloroadenosine on the nucleotide content of isolated rat hepatocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Adenosine Kinase; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Kinetics; Liver; Male; Nucleotides; Phosphorylation; Piperazines; Rats; Rats, Inbred Strains; Spectrophotometry; Tubercidin | 1988 |
A study of the actions of P1-purinoceptor agonists and antagonists in the mouse vas deferens in vitro.
Topics: 2-Chloroadenosine; Adenosine; Animals; Electrophysiology; Evoked Potentials; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Motor Endplate; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phenylisopropyladenosine; Receptors, Purinergic; Vas Deferens | 1988 |
Adenosine receptor activation blocks seizures induced by bicuculline methiodide in the rat prepiriform cortex.
Topics: 2-Chloroadenosine; Adenosine; Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Stereotyped Behavior | 1988 |
Discriminative-stimulus effects of adenosine analogs: mediation by adenosine A2 receptors.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Discrimination Learning; Drug Interactions; Male; Phenylisopropyladenosine; Receptors, Purinergic; Saimiri; Stereoisomerism | 1988 |
Potentiation of the anti-lipolytic effect of 2-chloroadenosine after chronic caffeine treatment.
Topics: 2-Chloroadenosine; Adenosine; Adipose Tissue; Animals; Body Weight; Caffeine; Cell Membrane; Drug Synergism; In Vitro Techniques; Lipolysis; Male; Organ Size; Radioligand Assay; Rats; Rats, Inbred Strains; Xanthines | 1988 |
Effects of adenosine and its analogues on porcine basilar arteries: are only A2 receptors involved?
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Basilar Artery; Dinoprost; Dose-Response Relationship, Drug; Phenylisopropyladenosine; Prostaglandins F; Receptors, Purinergic; Swine; Theophylline; Vasodilation; Vasodilator Agents | 1988 |
Interactions between caffeine and adenosine agonists in producing embryo resorptions and malformations in mice.
Topics: 2-Chloroadenosine; Abnormalities, Drug-Induced; Adenosine; Animals; Body Weight; Caffeine; Drug Administration Schedule; Drug Synergism; Embryo Loss; Female; Fetal Death; Mice; Mice, Inbred Strains; Phenylisopropyladenosine; Pregnancy | 1987 |
P1- and P2-purine receptors in brain circulation.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cats; Cerebral Arteries; Cerebrovascular Circulation; Female; Humans; In Vitro Techniques; Male; Rabbits; Receptors, Purinergic; Vasodilation | 1987 |
An adenosine analogue, 2-chloroadenosine, protects against long term development of ischaemic cell loss in the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain Ischemia; Cell Survival; Hippocampus; Male; Rats; Rats, Inbred Strains | 1987 |
Renovascular effects of adenosine receptor agonists.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Female; Rats; Receptors, Purinergic; Renal Artery; Renal Circulation; Renal Veins; Vasodilator Agents; Vasomotor System | 1987 |
Occurrence of an ascamycin dealanylating enzyme, Xc-aminopeptidase, in mammalian cell membranes and susceptibility to ascamycin.
Topics: 2-Chloroadenosine; Adenosine; Aminopeptidases; Animals; Anti-Bacterial Agents; Biological Transport; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Fluorescent Antibody Technique; Mice; Xanthomonas | 1986 |
Macrophage involvement in the antitumor activity of a synthetic acyltripeptide (FK-565) against experimental lung carcinoma metastases.
Topics: 2-Chloroadenosine; Adenosine; Adjuvants, Immunologic; Animals; Antineoplastic Agents; Diaminopimelic Acid; In Vitro Techniques; Lung Neoplasms; Lymphokines; Macrophage Activation; Macrophage-Activating Factors; Male; Mice; Mice, Inbred BALB C; Oligopeptides | 1986 |
Ventilatory effects of adenosine mediated by carotid body chemoreceptors in the rat.
Topics: 2-Chloroadenosine; Adenosine; Anesthesia; Animals; Blood Pressure; Carotid Body; Chemoreceptor Cells; Cyanides; Injections, Intravenous; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Respiration; Urethane | 1987 |
Effects of adenosine infusion into renal interstitium on renal hemodynamics.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Rats; Regional Blood Flow; Theophylline | 1987 |
Behavioral and cardiovascular effects of analogs of adenosine in cynomolgus monkeys.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Behavior, Animal; Blood Pressure; Caffeine; Cardiovascular System; Clonidine; Cocaine; Dextroamphetamine; Heart Rate; Isomerism; Macaca fascicularis; Male; Phenylisopropyladenosine | 1987 |
Isolation of a factor that reverses presynaptic inhibition of acetylcholine release.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Brain; Brain Chemistry; Clonidine; Dimethylphenylpiperazinium Iodide; Guinea Pigs; Morphine; Myenteric Plexus; Neuromuscular Junction; Oxotremorine; Phenylisopropyladenosine; Synapses; Synaptosomes | 1986 |
Nucleoside transport in guinea pig myocytes. Comparison of the affinities and transport velocities for adenosine and 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding Sites; Biological Transport; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Myocardium; Thioinosine; Tritium | 1987 |
An antiadrenergic effect of adenosine on guinea-pig but not rabbit ventricles.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenylyl Cyclase Inhibitors; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Papillary Muscles; Phenylisopropyladenosine; Rabbits; Species Specificity; Sympatholytics; Theophylline | 1987 |
Intestinal arteriolar responses to mucosal and serosal applications of adenosine analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Administration, Topical; Animals; Hemodynamics; Intestinal Mucosa; Jejunum; Male; Microcirculation; Microscopy; Rats; Rats, Inbred Strains; Receptors, Purinergic; Serous Membrane; Video Recording | 1987 |
Depressor and pressor actions of purine nucleosides and nucleotides in the anaesthetized rat.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Pressure; Cardiac Output; Injections, Intra-Arterial; Male; Nucleotides; Purine Nucleosides; Rats; Rats, Inbred Strains | 1987 |
Pharmacological characterization of CGS 15943A: a novel nonxanthine adenosine antagonist.
Topics: 2-Chloroadenosine; Adenosine; Animals; Blood Pressure; Coronary Vessels; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Trachea; Triazoles | 1987 |
Apparent affinity of some 8-phenyl-substituted xanthines at adenosine receptors in guinea-pig aorta and atria.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cell Membrane; Guinea Pigs; Heart; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardium; Receptors, Purinergic; Xanthines | 1987 |
Pertussis toxin reduces the antiadrenergic effect of 2-chloroadenosine on papillary muscle and the direct negative inotropic effect of 2-chloroadenosine on atrium.
Topics: 2-Chloroadenosine; Adenosine; Animals; Guinea Pigs; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxants, Central; Myocardial Contraction; Papillary Muscles; Pertussis Toxin; Sympatholytics; Theophylline; Virulence Factors, Bordetella | 1987 |
Effect of dipyridamole on spontaneous platelet aggregation in whole blood decreases with the time after venepuncture: evidence for the role of ADP.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Dipyridamole; Erythrocytes; Humans; In Vitro Techniques; Platelet Aggregation; Receptors, Purinergic | 1987 |
Effects of 2-chloroadenosine on hippocampal GABA content and turnover.
Topics: 2-Chloroadenosine; 4-Aminobutyrate Transaminase; Adenosine; Aminooxyacetic Acid; Animals; Caffeine; gamma-Aminobutyric Acid; Hippocampus; Injections, Intraventricular; Kinetics; Male; Rats; Rats, Inbred Strains | 1986 |
The effect of adenosine and chloroadenosine on sex differences in the energy metabolism of rat hepatocytes.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Adenosine; Animals; Energy Metabolism; Female; Gluconeogenesis; Glucose; Glycolysis; In Vitro Techniques; Liver; Liver Glycogen; Male; Mitochondria, Liver; Oleic Acid; Oleic Acids; Pyruvates; Rats | 1986 |
Adenosine analogues. The temperature-dependence of the anticonvulsant effect and inhibition of 3H-D-aspartate release.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticonvulsants; Aspartic Acid; Body Temperature; Dose-Response Relationship, Drug; Female; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred DBA; Motor Activity; Potassium; Rats; Rats, Inbred Strains; Theophylline; Tritium | 1986 |
Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Cell Adhesion; Endothelium; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Umbilical Veins | 1986 |
The effects of central injections of adenosine analogs on blood pressure and heart rate in the rat.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diastole; Heart Rate; Injections, Intraventricular; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Systole | 1986 |
Purification and characterization of ascamycin-hydrolysing aminopeptidase from Xanthomonas citri.
Topics: 2-Chloroadenosine; Adenosine; Aminopeptidases; Cations, Divalent; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Isoelectric Point; Molecular Weight; Substrate Specificity; Xanthomonas | 1986 |
Inability of anti-asialo-GM1 and 2-chloroadenosine to abrogate maleic anhydride-divinyl ether-induced resistance against experimental murine lung carcinoma metastases.
Topics: 2-Chloroadenosine; Adenosine; Animals; Antibodies; Antigen-Antibody Reactions; Cytotoxicity, Immunologic; G(M1) Ganglioside; Glycosphingolipids; Immunity, Cellular; Immunologic Surveillance; Killer Cells, Natural; Lung Neoplasms; Macrophages; Mice; Mice, Inbred BALB C; Polymers; Pyran Copolymer | 1986 |
Isolation of a factor (substance B) that antagonizes presynaptic modulation: pharmacological properties.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Brain Chemistry; Clonidine; Guinea Pigs; Hexamethonium Compounds; Ileum; Morphine; Muscle Contraction; Oxotremorine; Phencyclidine; Phenylisopropyladenosine; Synaptosomes | 1986 |
2-Chloroadenosine is phosphorylated and increases the production of hypoxanthine in human cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Kinase; Cell Line; Cell Survival; Drug Resistance; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Methylthioinosine; Phosphorylation; Purine Nucleotides | 1986 |
The membrane attack complex of complement induces permeability changes via thresholds in individual cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cell Membrane Permeability; Complement Membrane Attack Complex; Complement System Proteins; Cytotoxicity, Immunologic; Flow Cytometry; Humans; Neutrophils; Propidium; Rats; Rats, Inbred Strains; Time Factors | 1987 |
An in vitro analysis of purine-mediated renal vasoconstriction in rat isolated kidney.
Topics: 2-Chloroadenosine; Adenosine; Animals; Colforsin; Male; Methoxamine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Renal Circulation; Theophylline; Vasoconstriction; Xanthines | 1987 |
Heterogeneity of binding sites for N-ethylcarboxamido[3H]adenosine in rat brain: effects of N-ethylmaleimide.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Autoradiography; Binding Sites; Brain; Cell Membrane; Ethylmaleimide; Radioligand Assay; Rats; Subcellular Fractions | 1986 |
Regulation of cerebral blood flow (CBF) during hypoxia and epileptic seizures.
Topics: 2-Chloroadenosine; Adenosine; Amobarbital; Animals; Cats; Cerebrovascular Circulation; Cyanides; Epilepsy; Hypoxia; Theophylline | 1985 |
Prostaglandin E2 and 2-chloroadenosine act in concert to stimulate bone resorption in cultured murine calvarial bones.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bone Resorption; Calcium; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Indomethacin; Mice; Parathyroid Hormone; Prostaglandins E; Skull | 1985 |
Inhibition of antibody production by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Adenosine Deaminase Inhibitors; Animals; Antibody Formation; B-Lymphocytes; Cells, Cultured; DNA Replication; Homocysteine; Immunosuppressive Agents; Lymphocyte Activation; Male; Methylation; Mice; S-Adenosylmethionine | 1985 |
Effects of aminophylline and 2-chloroadenosine on seizures produced by pilocarpine in rats: morphological and electroencephalographic correlates.
Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Animals; Benzodiazepinones; Bicuculline; Brain; Carbolines; Convulsants; Electroencephalography; Flumazenil; Male; Motor Activity; Pilocarpine; Rats; Rats, Inbred Strains; Seizures | 1985 |
Depletion of monocytes from bovine mononuclear cells and the influence of monocyte depletion and some metabolic inhibitors on mitogen induced blastogenic response.
Topics: 2-Chloroadenosine; Adenosine; Animals; Blastomeres; Cattle; Concanavalin A; Indomethacin; Lymphocyte Activation; Mitogens; Mitomycin; Mitomycins; Monocytes; Phytohemagglutinins | 1985 |
Trans-stimulation and trans-inhibition of uridine efflux from human erythrocytes by permeant nucleosides.
Topics: 2-Chloroadenosine; Adenosine; Biological Transport; Erythrocytes; Humans; Nucleosides; Uridine | 1986 |
Cerebral oxygen tension in rats during deliberate hypotension with sodium nitroprusside, 2-chloroadenosine, or deep isoflurane anesthesia.
Topics: 2-Chloroadenosine; Adenosine; Anesthesia; Animals; Blood Pressure; Brain; Cyanides; Ferricyanides; Heart Rate; Hypotension, Controlled; Isoflurane; Male; Methyl Ethers; Nitroprusside; Oxygen; Partial Pressure; Rats; Rats, Inbred Strains | 1986 |
2-Chloroadenosine: a selective lethal effect to mouse macrophages and its mechanism.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Ascitic Fluid; Cell Line; Cell Membrane; Cell Survival; Coformycin; Female; Iodoacetates; Iodoacetic Acid; Kinetics; Macrophages; Methylation; Mice; Purine Nucleosides | 1985 |
2-Chloroadenosine inhibits complement-induced reactive oxygen metabolite production and recovery of human polymorphonuclear leucocytes attacked by complement.
Topics: 2-Chloroadenosine; Adenosine; Antibodies, Monoclonal; Cell Membrane; Complement Activation; Complement Inactivator Proteins; Humans; Immunoglobulin M; Luminescent Measurements; Neutrophils; Oxygen | 1985 |
Synaptosomal calcium uptake unaltered by adenosine and 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Calcium; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Synaptosomes | 1985 |
Sinus slowing and pacemaker shift caused by adenosine in rabbit SA node.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dose-Response Relationship, Drug; Heart; Heart Conduction System; In Vitro Techniques; Perfusion; Rabbits; Sinoatrial Node | 1985 |
Inhibition by adenosine of reactive oxygen metabolite production by human polymorphonuclear leucocytes.
Topics: 2-Chloroadenosine; Adenosine; Cytochalasin B; Free Radicals; Humans; Latex; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxygen; Theophylline | 1985 |
Effect of adenosine and its stabile analogue 2-chloroadenosine on cerebrocortical microcirculation and NAD/NADH redox state.
Topics: 2-Chloroadenosine; Adenosine; Administration, Topical; Animals; Cats; Cerebral Cortex; Dose-Response Relationship, Drug; Male; Microcirculation; NAD; Osmolar Concentration; Oxidation-Reduction | 1985 |
2-Chloroadenosine, a permeant for the nucleoside transporter.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Biological Transport; Blood Proteins; Carrier Proteins; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Thioinosine; Uridine | 1985 |
Possible mechanism of action of diazepam as an adenosine potentiator.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Animals; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; In Vitro Techniques; Intestines; Male; Muscle Contraction; Myocardial Contraction; Myocardium; Rats | 1985 |
Effects of 2-chloroadenosine on amygdaloid and hippocampal kindled seizures.
Topics: 2-Chloroadenosine; Adenosine; Amygdala; Animals; Electroencephalography; Hippocampus; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Seizures | 1985 |
Adenosine inhibits cell division and promotes neurite extension in PC12 cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenylyl Cyclases; Animals; Axons; Cell Division; Cell Line; Cyclic AMP; Drug Synergism; Nerve Growth Factors; Neurons; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Effects of adenosine receptor agonists in the isolated, perfused rat kidney.
Topics: 2-Chloroadenosine; Absorption; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Diuresis; Female; Hemodynamics; In Vitro Techniques; Kidney; Perfusion; Potassium; Pressure; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Renin; Sodium | 1984 |
Increased insulin sensitivity in soleus muscle from cold-exposed rats: reversal by an adenosine-receptor agonist.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbon Radioisotopes; Cold Temperature; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Male; Muscles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Inhibition by adenosine analogs of opiate withdrawal effects.
Topics: 2-Chloroadenosine; Adenosine; Animals; Behavior, Animal; Chlordiazepoxide; Guinea Pigs; Humans; Ileum; Male; Mice; Mice, Inbred Strains; Morphine Dependence; Morphine Derivatives; Muscle Contraction; Myenteric Plexus; Naloxone; Receptors, Cell Surface; Receptors, Purinergic; Substance Withdrawal Syndrome | 1984 |
Enhancement of tetrodotoxin-induced axonal blockade by adenosine, adenosine analogues, dibutyryl cyclic AMP and methylxanthines in the frog sciatic nerve.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Axons; Bucladesine; In Vitro Techniques; Phenylisopropyladenosine; Rana ridibunda; Sciatic Nerve; Tetrodotoxin; Xanthines | 1984 |
Adenosine and its derivatives inhibit the cAMP signaling response in Dictyostelium discoideum.
Topics: 2-Chloroadenosine; Adenosine; Cyclic AMP; Dictyostelium; Kinetics | 1984 |
Adenosine receptor mediated inhibition of noradrenaline release from slices of the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Calcium; Dipyridamole; Electric Stimulation; Hippocampus; Male; Norepinephrine; Phenylisopropyladenosine; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Rolipram; Theophylline; Xanthines | 1984 |
Modulation of alpha 2-adrenergic receptors of rat vas deferens by adenosine receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding Sites; Clonidine; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Cell Surface; Receptors, Purinergic; Vas Deferens; Yohimbine | 1984 |
Mutants of PC12 cells with altered cyclic AMP responses.
Topics: 2-Chloroadenosine; 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases; Adrenal Gland Neoplasms; Animals; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Diterpenes; Mutation; Phenotype; Pheochromocytoma; Rats | 1984 |
Adenosine analogues stimulate cyclic AMP-accumulation in cultured neuroblastoma and glioma cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cell Line; Cells, Cultured; Cyclic AMP; Glioma; Humans; Kinetics; Neuroblastoma; Phenylisopropyladenosine; Phosphoric Diester Hydrolases; Pyrrolidinones; Rolipram; Theophylline; Vasodilator Agents | 1984 |
Inhibitory effect of adenosine on transmission in sympathetic ganglia.
Topics: 2-Chloroadenosine; 4-Aminopyridine; Action Potentials; Adenosine; Aminopyridines; Animals; Dipyridamole; Electric Stimulation; Female; Ganglia, Sympathetic; In Vitro Techniques; Neuromuscular Depolarizing Agents; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1984 |
Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Atropine; Choline; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pyrrolidinones; Rolipram; Synaptic Transmission; Tetrodotoxin; Theophylline | 1984 |
Purine involvement in morphine antinociception.
Topics: 2-Chloroadenosine; Adenosine; Analgesia; Animals; Body Temperature; Bucladesine; Caffeine; Male; Morphine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains | 1984 |
Effects of adenosine, adenosine triphosphate and structural analogues on glucagon secretion from the perfused pancreas of rat in vitro.
Topics: 2-Chloroadenosine; 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Glucagon; In Vitro Techniques; Male; Nucleotidases; Pancreas; Rats; Theophylline | 1984 |
Activation of tyrosine 3-monooxygenase in pheochromocytoma cells by adenosine.
Topics: 2-Chloroadenosine; Adenosine; Adrenal Gland Neoplasms; Calcium; Cholera Toxin; Cyclic AMP; Dihydroxyphenylalanine; Enzyme Activation; Humans; Kinetics; Norepinephrine; Pheochromocytoma; Tyrosine 3-Monooxygenase | 1981 |
Inhibition of acetylcholine turnover rate in rat hippocampus and cortex by intraventricular injection of adenosine analogs.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Cerebral Cortex; Hippocampus; Male; Neurotransmitter Agents; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, Purinergic; Theophylline | 1982 |
Swelling and ion uptake in cat cerebrocortical slices: control by neurotransmitters and ion transport mechanisms.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bicarbonates; Cats; Cerebral Cortex; Chlorides; Histamine; Neurotransmitter Agents; Norepinephrine; Potassium; Sodium | 1983 |
Regulation of depolarization-dependent release of neurotransmitters by adenosine: cyclic AMP-dependent enhancement of release from PC12 cells.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Adrenal Gland Neoplasms; Animals; Cell Line; Cyclic AMP; Deoxyadenosines; Dideoxyadenosine; Methylation; Neurotransmitter Agents; Pheochromocytoma; Phosphatidylethanolamines; Rats | 1983 |
An adenosine agonist inhibits and a cyclic AMP analogue enhances the release of glutamate but not GABA from slices of rat dentate gyrus.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kinetics; Male; Potassium; Rats; Theophylline | 1983 |
Control of transmitter release in guinea-pig vas deferens by prejunctional P1-purinoceptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Triphosphate; Animals; Dipyridamole; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Neurotransmitter Agents; Norepinephrine; Receptors, Neurotransmitter; Receptors, Purinergic; Theophylline; Vas Deferens | 1984 |
Adenosine-elicited accumulation of adenosine 3', 5'-cyclic monophosphate in the chick embryo retina.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Cells, Cultured; Chick Embryo; Cyclic AMP; Dopamine Antagonists; Retina | 1982 |
Neuropharmacology of 3-isobutylmethylxanthine: effects on central noradrenergic systems in vivo.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Axons; Brain; Clonidine; Diazepam; Dihydroxyphenylalanine; Hydroxylation; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats; Rats, Inbred Strains; Stimulation, Chemical; Theophylline; Tyrosine 3-Monooxygenase; Yohimbine | 1983 |
Effects of analogues of adenosine and methyl xanthines on insulin sensitivity in soleus muscle of the rat.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Muscles; Phenylisopropyladenosine; Rats; Theophylline | 1984 |
Role of adenosine as an endogenous regulator of respiration in hamster brown adipocytes.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adipose Tissue, Brown; Animals; Cricetinae; Deoxyadenosines; Dideoxyadenosine; Isoproterenol; Lipolysis; Male; Mesocricetus; Oxygen Consumption | 1984 |
Adenosine and adenosine analogues stimulate adenosine cyclic 3', 5'-monophosphate-dependent chloride secretion in the mammalian ileum.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Transport; Chlorides; Cyclic AMP; Cyclic GMP; Ileum; Kinetics; Male; Phenylisopropyladenosine; Rabbits; Theophylline | 1984 |
Adenosine-binding to cerebral preparations in interpretation of adenosine activation of adenosine 3':5'-cyclic monophosphate formation [proceedings].
Topics: 2-Chloroadenosine; Adenosine; Animals; Cattle; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Kinetics; Mitochondria; Radioligand Assay; Rats; Synaptosomes; Theophylline; Tritium | 1980 |
Change of cycle AMP level in synaptosomes from cerebral cortex; increase by adenosine derivatives.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Cerebral Cortex; Cyclic AMP; Guinea Pigs; Male; Microsomes; Mitochondria; Nucleoside Deaminases; Stimulation, Chemical; Synaptosomes; Theophylline | 1981 |
Inhibition of cyclic AMP phosphodiesterase by 5'-deoxy-5'-S-isobutylthioadenosine at biologically active concentrations of drug.
Topics: 2-Chloroadenosine; 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenylyl Cyclases; Animals; Antineoplastic Agents; Cholera Toxin; Deoxyadenosines; Enzyme Activation; Isoproterenol; Kinetics; Lymphocytes; Mice; Prostaglandins E; Thionucleosides | 1981 |
Purine amplification of luteinizing hormone action in ovarian luteal cells.
Topics: 2-Chloroadenosine; Adenine; Adenine Nucleotides; Adenosine; Androgens; Animals; Corpus Luteum; Cyclic AMP; Female; Kinetics; Luteinizing Hormone; Progesterone; Purines; Rats | 1981 |
Antagonism of presynaptic adenosine receptors by theophylline 9-beta-D-riboside and 8-phenyltheophylline.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Dose-Response Relationship, Drug; Drug Antagonism; In Vitro Techniques; Male; Purine Nucleosides; Rats; Receptors, Adrenergic; Synaptic Transmission; Theophylline; Vas Deferens | 1981 |
Desensitization of adenylate cyclase to prostaglandin E1 or 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Alprostadil; Cyclic AMP; Cyclic GMP; Cycloheximide; Enzyme Activation; Glioma; Hybrid Cells; Kinetics; Neoplasms, Experimental; Neuroblastoma; Prostaglandins E; Time Factors | 1981 |
Properties of calcium receptors that initiate depolarization-secretion coupling.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Anura; Binding, Competitive; Calcium; Calcium-Binding Proteins; Cations, Divalent; Cytoplasmic Granules; Ion Channels; Lanthanum; Motor Neurons; Strontium | 1982 |
An A1-adenosine receptor, characterized by [3H] cyclohexyladenosine binding, mediates the depression of evoked potentials in a rat hippocampal slice preparation.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dose-Response Relationship, Drug; Evoked Potentials; Hippocampus; In Vitro Techniques; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, Purinergic | 1982 |
pp60src-Dependent increase in adenosine-stimulated cAMP formation.
Topics: 2-Chloroadenosine; Adenosine; Animals; Avian Leukosis Virus; Avian Sarcoma Viruses; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cyclic AMP; Defective Viruses; Kinetics; Mutation; Oncogene Protein pp60(v-src); Temperature; Viral Proteins | 1982 |
Adenosine receptors in rat brain membranes: characterization of high affinity binding of [3H]-2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Cell Membrane; Cerebral Cortex; Rats; Receptors, Cell Surface; Receptors, Purinergic; Subcellular Fractions | 1982 |
Evidence for an A2/Ra adenosine receptor in the guinea-pig trachea.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Receptors, Cell Surface; Receptors, Purinergic; Theophylline; Trachea | 1982 |
2-chloroadenosine increases calcium mobilization from mouse calvaria in vitro.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenine; Adenosine; Animals; Bone and Bones; Bone Resorption; Calcium; Cells, Cultured; Cyclic AMP; Mice; Purines | 1982 |
Interaction of adenosine 3',5'-monophosphate derivatives with the gonadotropin-releasing hormone receptor on pituitary and ovary.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine Monophosphate; Animals; Bucladesine; Cattle; Cyclic AMP; Female; Male; Ovary; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, LHRH; Thionucleotides | 1982 |
Regulation of glycogenolysis in transformed astrocytes in vitro.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Astrocytes; Brain; Cell Transformation, Viral; Cells, Cultured; Glycogen; Histamine; Isoproterenol; Kinetics; Norepinephrine; Phenylephrine; Rats; Serotonin; Simplexvirus | 1983 |
Interaction of 2-phenylaminoadenosine (CV 1808) with adenosine systems in rat tissues.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dipyridamole; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Vas Deferens; Vasodilator Agents | 1982 |
Mechanism of adenosine inhibition of catecholamine-induced responses in heart.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Cyclic AMP; Glycogen; Isoproterenol; Male; Myocardial Contraction; Myocardium; Phosphorylases; Protein Kinases; Rats; Rats, Inbred Strains; Time Factors; Ventricular Function | 1983 |
Discriminative stimulus properties of L-phenylisopropyl adenosine: blockade by caffeine and generalization to 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Caffeine; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Psychological; Male; Phenylisopropyladenosine; Rats; Receptors, Cell Surface; Receptors, Purinergic | 1983 |
Binding characteristics of an adenosine receptor in human placenta.
Topics: 2-Chloroadenosine; Adenosine; Binding, Competitive; Female; Humans; Kinetics; Microsomes; Placenta; Pregnancy; Receptors, Cell Surface; Receptors, Purinergic | 1983 |
The ionic basis of adenosine receptor actions on post-ganglionic neurones in the rat.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Autonomic Fibers, Postganglionic; Calcium; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Rats; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1983 |
Autoradiographic demonstration of peripheral adenosine binding sites using [3H]NECA.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Brain; Cecum; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Myenteric Plexus; Receptors, Cell Surface; Receptors, Purinergic | 1983 |
Subclasses of adenosine receptors in the central nervous system: interaction with caffeine and related methylxanthines.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Brain; Caffeine; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theobromine; Theophylline; Xanthines | 1983 |
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase; Calcimycin; Cell Aggregation; Coformycin; Cytochalasin B; Cytoplasmic Granules; Depression, Chemical; Dipyridamole; Humans; Methylation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pentostatin; Superoxides | 1983 |
The adenosine agonist 2-chloroadenosine inhibits the induction of long-term potentiation of the perforant path.
Topics: 2-Chloroadenosine; Adenosine; Animals; Calcium; Depression, Chemical; Evoked Potentials; Hippocampus; Ion Channels; Limbic System; Male; Neural Pathways; Rats; Synaptic Transmission; Time Factors | 1983 |
Effect of purinergic substances on rectal temperature in mice: involvement of P1-purinoceptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Body Temperature; Dose-Response Relationship, Drug; Female; Histamine Antagonists; Male; Mice; Purines; Receptors, Cell Surface; Receptors, Purinergic; Serotonin Antagonists; Sympatholytics | 1983 |
Evidence for the presence of P1- and P2-purinoceptors in rat caecum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Caffeine; Cecum; Cyclic AMP; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Quinidine; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1983 |
Interaction between 2-chloroadenosine and alpha-adrenoceptors in rat vas deferens.
Topics: 2-Chloroadenosine; Adenosine; Animals; Clonidine; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens | 1984 |
Cyclic AMP-mediated potentiation of muscarinic hyperpolarization in neuroblastoma cells.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Acetylcholine; Adenosine; Alprostadil; Animals; Cyclic AMP; Dopamine; In Vitro Techniques; Iontophoresis; Membrane Potentials; Mice; Morphine; Muscarine; Neuroblastoma; Prostaglandins E | 1984 |
On the mechanism by which adenosine receptor activation inhibits the release of acetylcholine from motor nerve endings.
Topics: 2-Chloroadenosine; Acetylcholine; Action Potentials; Adenosine; Adenylyl Cyclase Inhibitors; Animals; Cations, Divalent; Electric Stimulation; In Vitro Techniques; Motor Endplate; Neuromuscular Junction; Rana pipiens; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
The ability of adenosine to decrease the concentration of fructose 2,6-bisphosphate in isolated hepatocytes. A cyclic AMP-mediated effect.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Cyclic AMP; Depression, Chemical; Dose-Response Relationship, Drug; Fructosediphosphates; Glucagon; Gluconeogenesis; Hexosediphosphates; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains | 1984 |
Relationship between phosphorylation and cytotoxicity of 2-chloroadenosine and 6-methylmercaptopurine riboside in human cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Kinase; B-Lymphocytes; Cell Line; Genetic Variation; Humans; Inosine; Methylthioinosine; Phosphorylation; Phosphotransferases | 1984 |
The effects of phospholipase and 2-chloroadenosine treatments on alpha 2-adrenoceptors in rat vas deferens.
Topics: 2-Chloroadenosine; Adenosine; Animals; Clonidine; In Vitro Techniques; Male; Phospholipases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vas Deferens; Yohimbine | 1984 |
Hormone and methylxanthine action on breast epithelial cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Breast; Breast Neoplasms; Caffeine; Cell Line; Cyclic AMP; Epithelium; Female; Fibrocystic Breast Disease; Humans; Mice; Terbutaline; Xanthines | 1984 |
Indirect evidence that purinergic modulation of perivascular adrenergic neurotransmission in the portal vein is a physiological process.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Blood Vessels; Drug Interactions; Guinea Pigs; Histocytochemistry; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Portal Vein; Purines; Quinacrine; Rabbits; Rats; Rats, Inbred Strains; Sympathectomy, Chemical; Sympathetic Nervous System; Synaptic Transmission; Theophylline | 1984 |
Renal effects of 2-chloroadenosine in the two-kidney Goldblatt rat.
Topics: 2-Chloroadenosine; Adenosine; Animals; Blood Pressure; Body Weight; Constriction; Female; Hemodynamics; Inulin; Kidney; p-Aminohippuric Acid; Potassium; Rats; Rats, Inbred Strains; Renin | 1984 |
Studies on the mechanisms by which 2-chloroadenosine stimulates bone resorption in tissue culture.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arachidonic Acid; Arachidonic Acids; Bone and Bones; Bone Resorption; Calcitriol; Calcium; Cell Survival; Culture Techniques; Dinoprostone; Glucuronidase; Mice; Parathyroid Hormone; Prostaglandins E | 1983 |
Mechanism of potentiation by diazepam of adenosine response.
Topics: 2-Chloroadenosine; Adenosine; Animals; Benzodiazepinones; Cecum; Diazepam; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Female; Flumazenil; Hypoxanthine; Hypoxanthines; Inosine; Male; Rats; Rats, Inbred Strains | 1984 |
Differential inhibition of lymphocyte function by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Cell Survival; Cytotoxicity, Immunologic; Humans; Immunosuppressive Agents; In Vitro Techniques; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Thymidine | 1984 |
Attempted antagonism of adenosine analogue induced depression of respiration.
Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Animals; Animals, Newborn; Blood Gas Analysis; Brain Chemistry; Depression, Chemical; Dopamine; Female; Injections, Intraventricular; Male; Naloxone; Neurons; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Respiration; Serotonin | 1984 |
Genetic evidence that chloroadenosine increases the specific activity of choline acetyltransferase in PC12 cells via modulation of an adenosine-dependent adenylate cyclase.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenylyl Cyclases; Animals; Cholera Toxin; Choline O-Acetyltransferase; Clone Cells; Nerve Growth Factors; Pheochromocytoma; Rats | 1984 |
Ascamycin and dealanylascamycin, nucleoside antibiotics from Streptomyces sp.
Topics: 2-Chloroadenosine; Adenosine; Anti-Bacterial Agents; Bacteria; Mass Spectrometry; Microbial Sensitivity Tests; Optical Rotation; Species Specificity; Streptomyces; Structure-Activity Relationship | 1984 |
Central effects of adenosine analogs on locomotor activity in mice and antagonism of caffeine.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Depression, Chemical; Dose-Response Relationship, Drug; Locomotion; Male; Mice; Motor Activity; Phenylisopropyladenosine | 1983 |
Mediation by the corticostriatal input of the in vivo increase in rat striatal acetylcholine content induced by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Brain; Corpus Striatum; Female; Kinetics; Rats; Rats, Inbred Strains; Theophylline | 1983 |
A simple and sensitive liquid chromatographic method for the determination of 5'-methylthioadenosine in tissues.
Topics: 2-Chloroadenosine; Adenosine; Animals; Chromatography, Ion Exchange; Chromatography, Liquid; Deoxyadenosines; Rats; Thionucleosides; Tissue Distribution | 1983 |
Adenosine modulation of amygdala kindling.
Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Amygdala; Animals; Caffeine; Differential Threshold; Kindling, Neurologic; Male; Papaverine; Rats; Rats, Inbred Strains; Seizures | 1984 |
Effects of vasoactive intestinal polypeptide, monoamines, prostaglandins, and 2-chloroadenosine on adenylate cyclase in rat cerebral microvessels.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Animals; Catecholamines; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Activation; Gastrointestinal Hormones; Guanine Nucleotides; Microcirculation; Phentolamine; Propranolol; Prostaglandins; Rats; Rats, Inbred Strains; Vasoactive Intestinal Peptide | 1983 |
Uptake of adenosine into cultured cerebral endothelium.
Topics: 2-Chloroadenosine; Adenosine; Animals; Biological Transport; Carbon Radioisotopes; Cell Line; Cells, Cultured; Cerebrovascular Circulation; Dipyridamole; Endothelium; Kinetics; Mice; Papaverine; Sucrose; Tritium | 1983 |
Aminophylline and kindled seizures.
Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Amygdala; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Kindling, Neurologic; Male; Rats; Rats, Inbred Strains; Seizures | 1983 |
Evidence for stereospecificity of the P1-purinoceptor.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Azides; Female; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Male; Receptors, Drug; Receptors, Purinergic; Stereoisomerism; Theophylline; Trachea | 1982 |
Vasodilation of the normal and ischemic canine mesenteric circulation.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dogs; Epoprostenol; Female; Hemodynamics; Male; Mesenteric Vascular Occlusion; Oxygen Consumption; Prostaglandins; Prostaglandins D; Splanchnic Circulation; Vasodilation | 1981 |
Potentiation of arginine-induced glucagon secretion by adenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine; Drug Synergism; Glucagon; Insulin; Insulin Secretion; Male; Pancreas; Phenylisopropyladenosine; Rats; Theophylline | 1981 |
Physicochemical characterization of a PMN-derived soluble fraction that enhances lymphocyte DNA synthesis.
Topics: 2-Chloroadenosine; Adenosine; Animals; Chemical Phenomena; Chemistry, Physical; DNA; Electrophoresis, Polyacrylamide Gel; Female; Isoelectric Focusing; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Macrophages; Male; Mice; Mice, Inbred C3H; Neutrophils; Solubility | 1982 |
Renal effects of 2-chloroadenosine and their antagonism by aminophylline in anesthetized rats.
Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Animals; Glomerular Filtration Rate; Kidney; Male; Potassium; Rats; Rats, Inbred Strains; Sodium | 1982 |
The potentiation of cardiac responses to adenosine by benzodiazepines.
Topics: 2-Chloroadenosine; Adenosine; Animals; Benzodiazepines; Dimethyl Sulfoxide; Dipyridamole; Drug Synergism; Guinea Pigs; Heart; In Vitro Techniques; Male | 1982 |
A new nucleosidic antibiotic AT-265.
Topics: 2-Chloroadenosine; Adenosine; Anti-Bacterial Agents; Bacteria; Chemical Phenomena; Chemistry; Fermentation; Streptomyces | 1982 |
Inhibition of macrophage function by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Antibody Formation; Ascitic Fluid; Binding, Competitive; Cell Survival; Concanavalin A; Cytotoxicity, Immunologic; Female; Immunosuppression Therapy; Lymph Nodes; Lymphocyte Activation; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Spleen | 1982 |
Adenosine receptors mediating cardiac depression.
Topics: 2-Chloroadenosine; Adenosine; Animals; Depression, Chemical; Guinea Pigs; Heart Atria; Male; Myocardial Contraction; Phenylisopropyladenosine; Theophylline; Xanthines | 1982 |
Irreversible inhibition of S-adenosylhomocysteine hydrolase by nucleoside analogs.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosylhomocysteinase; Animals; Cattle; Chemical Phenomena; Chemistry; Hydrolases; Kinetics; Liver; Nucleosides; Structure-Activity Relationship; Vidarabine | 1981 |
Effects of 2-chloroadenosine on electric potentials in brain synaptic membrane vesicles.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain; Membrane Potentials; Onium Compounds; Potassium; Rats; Sodium Chloride; Succinates; Succinic Acid; Synaptic Membranes; Trityl Compounds; Valinomycin | 1981 |
The antilipolytic effect of endogenous and exogenous adenosine in canine adipose tissue in situ.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adipose Tissue; Animals; Dilazep; Dipyridamole; Dogs; Female; Lipolysis | 1981 |
2-chloroadenosine inhibits brain acetylcholine turnover in vivo.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Brain; Cerebral Cortex; Corpus Striatum; Female; Gas Chromatography-Mass Spectrometry; Hippocampus; Male; Rats; Rats, Inbred Strains | 1981 |
Behavioral characterization of two long-lasting adenosine analogs: sedative properties and interaction with diazepam.
Topics: 2-Chloroadenosine; Adenosine; Analgesia; Animals; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Exploratory Behavior; Hot Temperature; Hypnotics and Sedatives; Male; Mice; Motor Activity | 1981 |
High affinity binding of 2-chloroadenosine to rat brain synaptic membranes.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Binding Sites; Brain; Rats; Synaptic Membranes | 1980 |
Specific binding of 2-[3H]chloroadenosine to rat brain cortical membranes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding Sites; Cerebral Cortex; In Vitro Techniques; Male; Membranes; Rats | 1980 |
Adenosine-5'-uronamides rapidly desensitize the adenosine A2 receptor in coronary artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Coronary Vessels; Cyclohexanes; Humans; In Vitro Techniques; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Receptors, Purinergic P1; Structure-Activity Relationship; Swine; Tachyphylaxis | 1993 |
Inhibition of neutrophil adhesion by adenosine and an adenosine kinase inhibitor. The role of selectins.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Kinase; CD18 Antigens; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cytoskeleton; Depression, Chemical; E-Selectin; Endothelium, Vascular; Humans; Interleukin-1; L-Selectin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Ribonucleosides | 1995 |
Adenosine A1 agonists and the Ca2+ channel agonist bay K 8644 produce a synergistic stimulation of the GTPase activity of Go in rat frontal cortical membranes.
Topics: 2-Chloroadenosine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amino Acid Sequence; Animals; Calcium Channels; Cell Membrane; Drug Synergism; Frontal Lobe; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Molecular Sequence Data; Pertussis Toxin; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Virulence Factors, Bordetella | 1995 |
Adenosine modulates N-methyl-D-aspartate-stimulated hippocampal nitric oxide production in vivo.
Topics: 2-Chloroadenosine; Adenosine; Amino Acid Oxidoreductases; Animals; Arginine; Carbon Radioisotopes; Citrulline; Excitatory Amino Acid Antagonists; Hippocampus; Male; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norbornanes; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 1995 |
Contribution of P1-(A2b subtype) and P2-purinoceptors to the control of vascular tone in the rat isolated mesenteric arterial bed.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Adenosines scavenged hydroxyl radicals and prevented posttraumatic epilepsy.
Topics: 2-Chloroadenosine; Adenosine; Animals; Chlorides; Cyclic N-Oxides; Electroencephalography; Electron Spin Resonance Spectroscopy; Epilepsy, Post-Traumatic; Ferric Compounds; Free Radical Scavengers; Free Radicals; Hydroxyl Radical; Hypoxanthine; Hypoxanthines; Male; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides; Xanthine Oxidase | 1995 |
Effects of adenosine and 2-chloroadenosine on cerebral collateral vessels.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cerebrovascular Circulation; Collateral Circulation; Dogs; Microspheres | 1995 |
Inhibition of NMDA receptor-mediated currents in isolated rat hippocampal neurones by adenosine A1 receptor activation.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dose-Response Relationship, Drug; Hippocampus; Membrane Potentials; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1 | 1995 |
Comparison of the effect of isobutylmethylxanthine and phosphodiesterase-selective inhibitors on cAMP levels in SH-SY5Y neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Adenylyl Cyclase Inhibitors; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Phosphodiesterase Inhibitors; Pyrrolidinones; Rolipram; Tumor Cells, Cultured | 1993 |
A2 adenosine receptors in human glomerular mesangial cells.
Topics: 2-Chloroadenosine; 5'-Nucleotidase; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Glomerular Mesangium; Humans; Receptors, Purinergic P1; Tritium | 1995 |
Role of endothelium in hyperpolarization of coronary smooth muscle by adenosine and its analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Swine; Theophylline; Vasodilator Agents | 1995 |
Characterization of the facilitatory prejunctional purinoceptor on adrenergic nerves of the rabbit ear artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adrenergic Fibers; Animals; Arteries; Ear; Female; In Vitro Techniques; Male; Norepinephrine; Purinergic Agonists; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Theophylline | 1995 |
Adenosine stimulates DNA fragmentation in human thymocytes by Ca(2+)-mediated mechanisms.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Apoptosis; Calcium; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Child, Preschool; Cyclic AMP; DNA; DNA Damage; Enzyme Activation; Humans; Infant; Inositol Phosphates; Intracellular Fluid; Lymphocyte Count; Protein Kinase C; Purinergic P1 Receptor Agonists; Receptors, Antigen, T-Cell; Receptors, Purinergic P1; Stimulation, Chemical; T-Lymphocyte Subsets; Thymus Gland | 1994 |
Differentiation of the peripherally mediated from the centrally mediated influences of adenosine in the rat during systemic hypoxia.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Blood Gas Analysis; Blood Pressure; Heart Rate; Hemodynamics; Hypoxia; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Rats; Respiration; Theophylline; Vascular Resistance; Vasodilation | 1994 |
Adenosine modulation of primed human neutrophils.
Topics: 2-Chloroadenosine; Adenosine; Antihypertensive Agents; Drug Interactions; Humans; In Vitro Techniques; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phenethylamines; Receptors, Purinergic P1; Superoxides; Theophylline | 1994 |
Adenosine suppresses excitatory glutamatergic inputs to rat hypoglossal motoneurons in vitro.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Female; Hypoglossal Nerve; Kynurenic Acid; Male; Membrane Potentials; Motor Neurons; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Purinergic P1; Xanthines | 1994 |
Are negative chronotropic and inotropic responses to adenosine differentiated at the receptor or postreceptor levels in isolated dog hearts?
Topics: 2-Chloroadenosine; 4-Aminopyridine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Benzazepines; Depression, Chemical; Dogs; Heart Rate; In Vitro Techniques; Myocardial Contraction; Piperidines; Pyridines; Receptors, Purinergic P1; Xanthines | 1995 |
The effect of adenosine on cochlear potentials in the guinea pig.
Topics: 2-Chloroadenosine; Acoustic Stimulation; Action Potentials; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Cochlea; Cochlear Microphonic Potentials; Dose-Response Relationship, Drug; Guinea Pigs; Reaction Time | 1994 |
Possible evidence for involvement of new subtype of P1-purinoceptors in rat isolated uterus.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Female; In Vitro Techniques; Phenylisopropyladenosine; Rats; Receptors, Purinergic P1; Stereoisomerism; Uterine Contraction | 1994 |
A comparison of A2 adenosine receptor-induced cyclic AMP generation in cerebral cortex and relaxation of pre-contracted aorta.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta; Cerebral Cortex; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Vasodilator Agents; Xanthines | 1994 |
Adenosine A2B-receptor-mediated cyclic AMP accumulation in primary rat astrocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Astrocytes; Cells, Cultured; Cyclic AMP; Dipyridamole; Dose-Response Relationship, Drug; Immunohistochemistry; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Xanthines | 1994 |
Dissociation of adenosine levels from bioenergetic state in experimental brain trauma: potential role in secondary injury.
Topics: 2-Chloroadenosine; Adenosine; Animals; Blood Pressure; Brain Injuries; Energy Metabolism; Kinetics; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Effect of an adenosine antagonist and an adenosine agonist on status entry and severity in a model of limbic status epilepticus.
Topics: 2-Chloroadenosine; Adenosine; Aminophylline; Amygdala; Animals; Behavior, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Complex Partial; Limbic System; Male; Rats; Rats, Sprague-Dawley; Status Epilepticus | 1994 |
Adenosine inhibits the NMDA receptor-mediated excitatory postsynaptic potential in the hippocampus.
Topics: 2-Chloroadenosine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Adenosine; Animals; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Magnesium; Male; Osmolar Concentration; Picrotoxin; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Characterization and localization of adenosine A2 receptors in bovine rod outer segments.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding, Competitive; Cattle; Electrophoresis, Polyacrylamide Gel; Phenethylamines; Receptors, Purinergic P1; Rod Cell Outer Segment; Subcellular Fractions; Tissue Distribution | 1994 |
A link between adenosine, ATP-sensitive K+ channels, potassium and muscle vasodilatation in the rat in systemic hypoxia.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Glyburide; Hypoxia; Muscles; Potassium; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Theophylline; Vasodilation | 1993 |
Adenosine A1 receptors are not involved in contraction of canine gastric muscularis mucosae by adenosine analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dogs; Drug Interactions; Female; Gastric Mucosa; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purinergic P1 Receptor Antagonists; Pyrilamine; Receptors, Purinergic P1; Stimulation, Chemical; Tetrodotoxin; Xanthines | 1994 |
Excitatory and inhibitory effects of A1 and A2A adenosine receptor activation on the electrically evoked [3H]acetylcholine release from different areas of the rat hippocampus.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Antihypertensive Agents; Cerebellar Nuclei; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Male; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Tritium; Xanthines | 1994 |
Characterization of adenosine receptor-mediated generation of cyclic AMP in slices of rat cerebral cortex with chronic epileptic activity.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cerebral Cortex; Chronic Disease; Cyclic AMP; Electroencephalography; Epilepsy; Ferrous Compounds; In Vitro Techniques; Male; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Purinergic P1 | 1993 |
Ionomycin-induced acetylcholine release and its inhibition by adenosine at frog motor nerve endings.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Calcium; In Vitro Techniques; Ionomycin; Membrane Potentials; Motor Neurons; Neuromuscular Junction; Rana pipiens | 1993 |
Involvement of adenosine-sensitive cyclic AMP-generating systems in cobalt-induced epileptic activity in the rat.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Animals; Cerebral Cortex; Cobalt; Cyclic AMP; Electroencephalography; Epilepsy; In Vitro Techniques; Male; Microinjections; Motor Activity; Rats; Rats, Wistar; Theophylline | 1993 |
Adenosine reduces the potassium conductance of guinea pig submucosal plexus neurons by activating protein kinase A.
Topics: 2-Chloroadenosine; Adenosine; Alkaloids; Animals; Cadmium; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Guinea Pigs; Membrane Potentials; Neurons; Phorbol 12,13-Dibutyrate; Potassium; Staurosporine; Submucous Plexus | 1993 |
Cardiac desensitization to adenosine analogues after prolonged R-PIA infusion in vivo.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carbachol; Down-Regulation; GTP-Binding Proteins; Heart; Heart Atria; In Vitro Techniques; Male; Myocardium; Phenylisopropyladenosine; Rats; Rats, Wistar; Receptors, Purinergic P1; Time Factors | 1993 |
Role of extracellular adenosine in ethanol-induced desensitization of cyclic AMP production.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; Ethanol; Extracellular Space; PC12 Cells | 1993 |
Regulation of adenosine receptor system in coronary artery: functional studies and cAMP.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arteries; Colforsin; Coronary Vessels; Cyclic AMP; Female; In Vitro Techniques; Male; Rabbits; Receptors, Purinergic; Sodium Fluoride; Swine; Vasodilation | 1993 |
Adenosine analogues with specificity for A2 receptors bind to mouse spermatozoa and stimulate adenylate cyclase activity in uncapacitated suspensions.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Cells, Cultured; Cyclic AMP; Male; Mice; Protein Binding; Receptors, Purinergic; Sperm Capacitation; Spermatozoa | 1993 |
Protective effect of 2-chloroadenosine on lung ischemia reperfusion injury.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bronchoalveolar Lavage Fluid; Hemodynamics; Ischemia; Lung; Male; Neutrophils; Rabbits; Reperfusion Injury | 1993 |
Stimulation of rat liver glycogen synthesis by the adenosine kinase inhibitor 5-iodotubercidin.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Kinase; Adenosine Triphosphate; Amino Acids; Animals; Cells, Cultured; Liver; Liver Glycogen; Male; Rats; Rats, Wistar; Tubercidin | 1993 |
Synergy between the inositol phosphate responses to transfected human adenosine A1-receptors and constitutive P2-purinoceptors in CHO-K1 cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cattle; Cells, Cultured; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Humans; Inositol Phosphates; Pertussis Toxin; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Uridine Triphosphate; Virulence Factors, Bordetella; Xanthines | 1995 |
Adenosine A2 receptor-mediated stimulation of cyclic AMP in cultured chicken pineal cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cells, Cultured; Chickens; Colforsin; Cyclic AMP; Kinetics; Pineal Gland; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1995 |
A1, but not A2A, adenosine receptors modulate electrically stimulated [14C]acetylcholine release from rat cortex.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Cerebral Cortex; Electric Stimulation; In Vitro Techniques; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Xanthines | 1996 |
Effect of adenosine on the expression of beta(2) integrins and L-selectin of human polymorphonuclear leukocytes in vitro.
Topics: 2-Chloroadenosine; Adenosine; CD18 Antigens; Dipyridamole; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; L-Selectin; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic P1; Xanthines | 1996 |
Evidence for high-affinity binding sites for the adenosine A2A receptor agonist [3H] CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Xanthines | 1996 |
Cellular mechanisms underlying adenosine actions on cholinergic transmission in enteric neurons.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Calcium; Calcium Channels; Electric Conductivity; Enteric Nervous System; Female; GTP-Binding Proteins; Guinea Pigs; Intestines; Male; Myenteric Plexus; Parasympathetic Nervous System; Patch-Clamp Techniques; Synaptic Transmission | 1996 |
The effects of 5'-N-ethylcarboxamidoadenosine on evoked release of [3H]serotonin in the rat nucleus tractus solitarius.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Analysis of Variance; Animals; Antihypertensive Agents; Binding, Competitive; Dopamine; Dose-Response Relationship, Drug; Electric Stimulation; gamma-Aminobutyric Acid; Male; Neurotransmitter Agents; Organ Culture Techniques; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Sensitivity and Specificity; Serotonin; Solitary Nucleus; Tritium; Vasodilator Agents; Xanthines | 1996 |
Chronic exposure to adenosine receptor agonists and antagonists reciprocally regulates the A1 adenosine receptor-adenylyl cyclase system in cerebellar granule cells.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Cerebellum; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Time Factors; Xanthines | 1996 |
Inosine mediates the protective effect of adenosine in rat astrocyte cultures subjected to combined glucose-oxygen deprivation.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Animals, Newborn; Astrocytes; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Glucose; Inosine; Kinetics; L-Lactate Dehydrogenase; Purines; Rats; Rats, Sprague-Dawley | 1996 |
Neurite outgrowth of striatal neurons in vitro: involvement of purines in the growth-promoting effect of myenteric plexus explants.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Aminohydrolases; Animals; Cells, Cultured; Colforsin; Drug Interactions; Fibroblast Growth Factors; Fibronectins; Gangliosides; Guanosine Triphosphate; Laminin; Myenteric Plexus; Neostriatum; Nerve Growth Factors; Neurites; Neurons; Neuropeptides; Neurotrophin 3; Rats; Rats, Sprague-Dawley; Serotonin; Tetrodotoxin; Theophylline | 1996 |
Effect of adenosine on phorbol myristate acetate induced-reactive oxygen metabolite production in cultured mesangial cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cells, Cultured; Colforsin; Cyclic AMP; Female; Glomerular Mesangium; Luminescent Measurements; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tetradecanoylphorbol Acetate | 1996 |
Adenosine-mediated inhibition of glutathione synthesis in rat isolated hepatocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Glucose; Glutathione; In Vitro Techniques; Liver; Male; Methionine; Rats; Rats, Wistar; Receptors, Purinergic P1; Vitamin K | 1996 |
Interruption of Escherichia coli heat-stable enterotoxin-induced guanylyl cyclase signaling and associated chloride current in human intestinal cells by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Bacterial Toxins; Caco-2 Cells; Chloride Channels; Enterotoxins; Enzyme Inhibitors; Escherichia coli Proteins; Guanylate Cyclase; Humans; Models, Biological; Pentostatin; Purinergic P1 Receptor Agonists; Signal Transduction | 1997 |
Adenosine A2A receptor stimulation increases release of acetylcholine from rat hippocampus but not striatum, and does not affect catecholamine release.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Catecholamines; Corpus Striatum; Hippocampus; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Xanthines | 1997 |
Postnatal development of the pattern of respiratory and cardiovascular response to systemic hypoxia in the piglet: the roles of adenosine.
Topics: 2-Chloroadenosine; Adenosine; Aging; Animals; Animals, Newborn; Cardiovascular System; Hypoxia; Respiration; Swine; Theophylline | 1996 |
Adenosine increases the cAMP content of the rat carotid body in vitro.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenine; Adenosine; Animals; Carotid Body; Cyclic AMP; Male; Nerve Tissue Proteins; Perfusion; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Second Messenger Systems | 1996 |
Adenosine inhibits superoxide production in rat peritoneal macrophages via elevation of cAMP level.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Bucladesine; Cyclic AMP; Enzyme Activation; Intracellular Fluid; Macrophages, Peritoneal; Male; Protein Kinase C; Rats; Rats, Wistar; Superoxides; Xanthines | 1997 |
Effects of adenosine on the functions of circulating polymorphonuclear leukocytes during hyperdynamic endotoxemia.
Topics: 2-Chloroadenosine; Adenosine; Animals; CD18 Antigens; Endotoxemia; Female; L-Selectin; Neutrophils; Phagocytosis; Superoxides; Swine | 1997 |
2-chloroadenosine stimulates granule exocytosis from mouse natural killer cells: evidence for signal transduction through a novel extracellular receptor.
Topics: 2-Chloroadenosine; Adenosine; Animals; Calcium; Cytoplasmic Granules; Dose-Response Relationship, Drug; Drug Interactions; Exocytosis; Female; GTP-Binding Proteins; Killer Cells, Natural; Mice; Mice, Inbred C57BL; Models, Biological; Protein Kinase Inhibitors; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Spleen | 1997 |
Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Catalepsy; Dopamine Antagonists; Haloperidol; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Scopolamine; Theobromine; Theophylline; Xanthines | 1997 |
Competition of adenine nucleotides for a 1,3-[3H]-dipropyl-8-cyclopentylxanthine binding site in rat vas deferens.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Binding Sites; Binding, Competitive; In Vitro Techniques; Kinetics; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Vas Deferens; Xanthines | 1997 |
Adenosine stimulates nitric oxide synthesis in rat cardiac myocytes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Animals, Newborn; Bucladesine; Cells, Cultured; Dactinomycin; Enzyme Inhibitors; Heart; Humans; Interleukin-1; Isoproterenol; Myocardium; Naphthalenes; Nitric Oxide; Nitrites; omega-N-Methylarginine; Protein Kinase C; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Stereoisomerism; Theophylline; Xanthines | 1997 |
Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Deaminase Inhibitors; Animals; Animals, Newborn; Brain Ischemia; Cell Survival; Enzyme Inhibitors; Hippocampus; Neurons; Neurotoxins; Nitric Oxide; Organ Culture Techniques; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1997 |
Effect of low density lipoprotein on adenosine receptor-mediated coronary vasorelaxation in vitro.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; In Vitro Techniques; Lipoproteins, LDL; Male; Nitrites; Oxidation-Reduction; Phenethylamines; Receptors, Purinergic P1; Swine; Vasodilation | 1997 |
Stimulation of interleukin-6 secretion and gene transcription in primary astrocytes by adenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Animals, Newborn; Astrocytes; Cerebral Cortex; Genes, Reporter; Humans; Interleukin-6; Kinetics; Mice; Phenethylamines; Purinergic P1 Receptor Agonists; Recombinant Fusion Proteins; Transcription, Genetic | 1997 |
Adenosine stimulates nitric oxide synthesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bucladesine; Cells, Cultured; Cyclic AMP; Interleukin-1; Muscle, Smooth, Vascular; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Vasodilator Agents | 1997 |
Adenosine receptor-mediated relaxation of rabbit airway smooth muscle: a role for nitric oxide.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Bronchi; Dose-Response Relationship, Drug; Epithelium; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Phenethylamines; Potassium Chloride; Purinergic P1 Receptor Agonists; Rabbits; Receptors, Purinergic P1 | 1997 |
An endogenous A2B adenosine receptor coupled to cyclic AMP generation in human embryonic kidney (HEK 293) cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Cells, Cultured; Cyclic AMP; DNA, Complementary; Gene Amplification; Humans; In Vitro Techniques; Kidney; Phenethylamines; Polymerase Chain Reaction; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Receptor, Adenosine A2B; Receptors, Purinergic P1; Triazoles | 1997 |
Adenosine stimulates Cl- channels of nonpigmented ciliary epithelial cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Monophosphate; Animals; Barium; Cattle; Cell Line; Cells, Cultured; Chloride Channels; Ciliary Body; Gramicidin; Humans; Kinetics; Male; Membrane Potentials; Niflumic Acid; Nitrobenzoates; Pigment Epithelium of Eye; Rabbits; Receptors, Purinergic P1; Time Factors | 1997 |
P2-receptor-mediated inhibition of serotonin release in the rat brain cortex.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebral Cortex; Desipramine; Dinucleoside Phosphates; In Vitro Techniques; Male; Methiothepin; Quipazine; Rats; Rats, Wistar; Receptors, Purinergic P2; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists | 1997 |
Modulation of lithium-pilocarpine-induced status epilepticus by adenosinergic agents.
Topics: 2-Chloroadenosine; Adenosine; Animals; Anticonvulsants; Carbamazepine; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Lithium; Male; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Theophylline; Vasodilator Agents | 1997 |
Adenosine-induced hyperpolarization in guinea pig coronary artery involves A2b receptors and KATP channels.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Membrane; Coronary Vessels; Endothelium, Vascular; Glyburide; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Nitroarginine; Potassium Channels; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2B; Receptors, Purinergic P1 | 1997 |
Cyclic AMP-adenosine pathway induces nitric oxide synthesis in aortic smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Aorta, Thoracic; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytosol; Dideoxyadenosine; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Signal Transduction; Thionucleotides | 1998 |
Adenosine inhibits growth of human aortic smooth muscle cells via A2B receptors.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adult; Animals; Aorta, Thoracic; Cell Division; Cells, Cultured; Collagen; Dipyridamole; DNA; Humans; Kinetics; Male; Muscle, Smooth, Vascular; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Receptor, Adenosine A2B; Receptors, Purinergic P1; Thymidine; Xanthines | 1998 |
Adenosine A2A receptors facilitate 45Ca2+ uptake through class A calcium channels in rat hippocampal CA3 but not CA1 synaptosomes.
Topics: 2-Chloroadenosine; Adenosine; Animals; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Hippocampus; Male; omega-Agatoxin IVA; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Spider Venoms; Synaptosomes; Veratridine; Xanthines | 1997 |
Adenosine inhibits collagen and protein synthesis in cardiac fibroblasts: role of A2B receptors.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cardiovascular Agents; Cell Culture Techniques; Cell Division; Collagen; Fibroblasts; Fibrosis; Heart Ventricles; Male; Myocardial Infarction; Protein Biosynthesis; Proteins; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1 | 1998 |
Adenosine A2 receptor mediation of pre- and postsynaptic excitatory effects of adenosine in rat hippocampus in vitro.
Topics: 2-Chloroadenosine; Adenosine; Animals; Excitatory Postsynaptic Potentials; Female; Hippocampus; Male; Phenethylamines; Rats; Receptors, Purinergic P1; Synaptic Transmission; Tetrodotoxin | 1998 |
Exogenous adenosine potentiates hypnosis induced by intravenous anaesthetics.
Topics: 2-Chloroadenosine; Adenosine; Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Dipyridamole; Drug Synergism; Female; Male; Mice; Midazolam; Propofol; Reflex; Sleep; Theophylline; Thiopental | 1998 |
Modulation of epileptiform activity by adenosine A1 receptor-mediated mechanisms in the juvenile rat hippocampus.
Topics: 2-Chloroadenosine; 4-Aminopyridine; Adenosine; Age Factors; Animals; Anticonvulsants; Barium; Dipyridamole; Hippocampus; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Purinergic P1 | 1998 |
Adenosine inhibits collagen and total protein synthesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Aorta, Abdominal; Cells, Cultured; Collagen; Cyclic AMP; Dipyridamole; Kinetics; Leucine; Male; Muscle, Smooth, Vascular; Proline; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Xanthines | 1999 |
2-Chloroadenosine reverses hyperglycemia-induced inhibition of phosphoinositide synthesis in cultured human retinal pigment epithelial cells and prevents reduced nerve conduction velocity in diabetic rats.
Topics: 2-Chloroadenosine; Adenosine; Adenylyl Cyclases; Aldehyde Reductase; Animals; CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase; Cells, Cultured; Diabetes Mellitus, Experimental; Glucose; GTP-Binding Proteins; Humans; Hyperglycemia; Male; Membrane Proteins; Neural Conduction; Phosphatidylinositols; Pigment Epithelium of Eye; Rats; Rats, Wistar; Signal Transduction; Transferases (Other Substituted Phosphate Groups); Type C Phospholipases | 1999 |
Anticonvulsant action of 2-chloroadenosine injected focally into the perirhinal cortex in amygdaloid kindled rats.
Topics: 2-Chloroadenosine; Adenosine; Amygdala; Analysis of Variance; Animals; Anticonvulsants; Caffeine; Dose-Response Relationship, Drug; Injections; Kindling, Neurologic; Male; Olfactory Pathways; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures | 1999 |
A(2B) receptors mediate antimitogenesis in vascular smooth muscle cells.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Adenosine Kinase; Adenosine-5'-(N-ethylcarboxamide); Animals; Anticoagulants; Antihypertensive Agents; Aorta, Abdominal; Becaplermin; Cell Division; Dinucleoside Phosphates; Enzyme Inhibitors; Hyperplasia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phenethylamines; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Thymidine; Tritium; Tubercidin; Vasodilator Agents; Xanthines | 2000 |
The potentiation of the histamine release induced by adenosine in mast cells from guinea pig lung and heart: sharp dependence on the time of preincubation.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bucladesine; Dipyridamole; Drug Interactions; Female; Guinea Pigs; Histamine Release; Lung; Male; Mast Cells; Myocardium; Theophylline; Time Factors; Vasodilator Agents | 2000 |
Chronotropic and vasodilatory responses to adenosine and isoproterenol in mouse heart: effects of adenosine A1 receptor overexpression.
Topics: 2-Chloroadenosine; Adenosine; Adrenergic beta-Agonists; Algorithms; Animals; Coronary Circulation; Female; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Mice; Mice, Transgenic; Myocardial Contraction; Receptors, Purinergic P1; Vascular Resistance; Vasodilator Agents | 2000 |
Adenosine regulates the production of interleukin-6 by human gingival fibroblasts via cyclic AMP/protein kinase A pathway.
Topics: 2-Chloroadenosine; Adenosine; Adjuvants, Immunologic; Analysis of Variance; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Fibroblasts; Gingiva; Humans; Interleukin-6; Periodontitis; Stimulation, Chemical | 2000 |
Adenosine- and 2-chloro-adenosine-induced cytopathic effects on myoblastic cells and myotubes: involvement of different intracellular mechanisms.
Topics: 2-Chloroadenosine; Acetylcysteine; Actin Cytoskeleton; Adenosine; Adenosine Kinase; Animals; Apoptosis; Cell Adhesion; Cell Line; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Homocysteine; Intracellular Fluid; Mice; Microscopy, Electron, Scanning; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Reactive Oxygen Species; Thioinosine; Tubercidin | 2000 |
Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Affinity Labels; Animals; Binding, Competitive; Cells, Cultured; Coronary Vessels; Cyclic AMP; Endothelium, Vascular; Gene Expression Regulation; Humans; Iodine Radioisotopes; Iodobenzenes; Kinetics; Phenethylamines; Purinergic P1 Receptor Antagonists; Radioligand Assay; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Reverse Transcriptase Polymerase Chain Reaction; Swine; Transcription, Genetic; Triazines; Triazoles | 2000 |
Failure of presynaptic purinoceptors to modulate noradrenaline release from sympathetic nerves in human dental pulp.
Topics: 2-Chloroadenosine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Culture Techniques; Dental Pulp; Desipramine; Humans; Norepinephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Radiopharmaceuticals; Receptors, Presynaptic; Receptors, Purinergic P1; Receptors, Purinergic P2; Sympathetic Nervous System; Sympathomimetics; Tritium; Xanthines; Yohimbine | 2000 |
Selective transport of adenosine into porcine coronary smooth muscle.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; Biological Transport; Carrier Proteins; Coronary Vessels; Dinoprost; Dipyridamole; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; In Vitro Techniques; Muscle, Smooth, Vascular; Purinergic P1 Receptor Agonists; Substrate Specificity; Swine; Thioinosine; Vasoconstriction; Vasodilation; Vasodilator Agents | 2000 |
Adenosine action on interneurons and synaptic transmission onto interneurons in rat hippocampus in vitro.
Topics: 2-Chloroadenosine; Adenosine; Animals; Anti-Arrhythmia Agents; Hippocampus; Interneurons; Male; Membrane Potentials; Purinergic P1 Receptor Agonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission | 2000 |
Characterisation of adenosine receptors mediating relaxation in hamster isolated aorta.
Topics: 2-Chloroadenosine; Adenosine; Animals; Aorta; Cricetinae; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mesocricetus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenethylamines; Receptors, Purinergic P1; Theophylline; Thioinosine; Vasodilation | 2000 |
A1 adenosine receptors inhibit multiple voltage-gated Ca2+ channel subtypes in acutely isolated rat basolateral amygdala neurons.
Topics: 2-Chloroadenosine; Adenosine; Amygdala; Animals; Calcium Channels; Ethylmaleimide; In Vitro Techniques; Ion Channel Gating; Male; omega-Agatoxin IVA; omega-Conotoxin GVIA; Rats; Receptors, Purinergic P1; Signal Transduction; Virulence Factors, Bordetella | 2001 |
A(2b) receptors mediate the antimitogenic effects of adenosine in cardiac fibroblasts.
Topics: 2-Chloroadenosine; Adenosine; Animals; Becaplermin; Cell Division; Cells, Cultured; Collagen; Cyclic AMP; DNA; Enzyme Activation; Fibroblasts; Hypertension; Male; Mitogen-Activated Protein Kinases; Mitogens; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oligonucleotides, Antisense; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2B; Receptors, Purinergic P1; Signal Transduction | 2001 |
Characterization of prejunctional purinoceptors inhibiting noradrenaline release in rat mesenteric arteries.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Clonidine; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats; Rats, Wistar; Tetrodotoxin; Xanthines | 2001 |
Effect of 9-(6,7-dideoxy-beta-D-allo-hept-5-ynofuranosyl)adenine on noradrenaline release from vascular sympathetic nerves.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Adrenergic Fibers; Animals; Ear; Male; Mesenteric Arteries; Norepinephrine; Purinergic P1 Receptor Agonists; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Thionucleotides; Vasodilator Agents | 2001 |
Interaction between angiotensin IV and adenosine A(1) receptor related drugs in passive avoidance conditioning in rats.
Topics: 2-Chloroadenosine; Adenosine; Angiotensin II; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraventricular; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 2001 |
Assessment of 2-chloroadenosine treatment after experimental traumatic brain injury in the rat using arterial spin-labeled MRI: a preliminary report.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain Concussion; Cerebral Cortex; Dose-Response Relationship, Drug; Image Enhancement; Injections; Magnetic Resonance Imaging; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2000 |
Functional characterization of coronary vascular adenosine receptors in the mouse.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glyburide; Heart; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase; Nitroarginine; Phenethylamines; Potassium Channel Blockers; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Vascular Resistance; Vasodilation; Vasodilator Agents | 2001 |
Purine nucleoside-dependent inhibition of cellular proliferation in 1321N1 human astrocytoma cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Astrocytoma; Brain Neoplasms; Cell Death; Cell Division; Humans; Purine Nucleosides; Purinergic P1 Receptor Antagonists; Theophylline; Tumor Cells, Cultured; Uridine Triphosphate | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pirenzepine; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Purinergic; Theophylline; Urinary Bladder | 2001 |
Adenosine regulates the IL-1 beta-induced cellular functions of human gingival fibroblasts.
Topics: 2-Chloroadenosine; Adenosine; Adjuvants, Immunologic; Cell Adhesion; Cells, Cultured; Collagen Type I; Collagen Type III; Down-Regulation; Drug Synergism; Fibroblasts; Fibronectins; Gingiva; Glucuronosyltransferase; Glycosyltransferases; Humans; Hyaluronan Synthases; Immunity, Cellular; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-6; Interleukin-8; Laminin; Membrane Proteins; Purinergic P1 Receptor Agonists; Receptor, Adenosine A3; Receptors, Purinergic P1; RNA, Messenger; T-Lymphocytes; Transferases; Xenopus Proteins | 2001 |
Comparison of the vascular effects of adenosine in isolated mouse heart and aorta.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Heart; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Perfusion; Phenethylamines | 2002 |
8-Cl-adenosine is an active metabolite of 8-Cl-cAMP responsible for its in vitro antiproliferative effects on CHO mutants hypersensitive to cytostatic drugs.
Topics: 2-Chloroadenosine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Antineoplastic Agents; Cell Division; Chlorine Compounds; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Temperature | 2001 |
[Adenosine in treatment of rats with spinal cord injury].
Topics: 2-Chloroadenosine; Adenosine; Animals; Calcium; Disease Models, Animal; Extracellular Space; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2000 |
Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors.
Topics: 2-Chloroadenosine; Action Potentials; Adenosine; Animals; Animals, Newborn; Calcium Channels; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; GTP-Binding Proteins; Hippocampus; Neurons; Patch-Clamp Techniques; Potassium Channels; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Signal Transduction; Synapses; Xanthines | 2002 |
2-Chloroadenosine but not adenosine induces apoptosis in rheumatoid fibroblasts independently of cell surface adenosine receptor signalling.
Topics: 2-Chloroadenosine; Adenosine; Analgesics; Apoptosis; Arthritis, Rheumatoid; Fibroblasts; HeLa Cells; Humans; Receptors, Cell Surface; Receptors, Purinergic P1; Signal Transduction; Synovial Membrane; Tumor Cells, Cultured | 2002 |
Persistence of the neuromodulatory effects of adenosine on synaptic transmission after long-term potentiation and long-term depression.
Topics: 2-Chloroadenosine; Adenosine; Analgesics; Animals; Dose-Response Relationship, Drug; Hippocampus; Long-Term Potentiation; Male; Neurotransmitter Agents; Rats; Rats, Wistar; Synaptic Transmission | 2002 |
Coronary function and adenosine receptor-mediated responses in ischemic-reperfused mouse heart.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Diphosphate; Animals; Caffeine; Coronary Circulation; Heart; Male; Mice; Mice, Inbred C57BL; Models, Animal; Myocardial Contraction; Myocardial Reperfusion Injury; Nitroprusside; Perfusion; Phenethylamines; Purinergic P1 Receptor Antagonists; Vasodilator Agents; Xanthines | 2002 |
Recovery of deficient cholinergic calcium signaling by adenosine in cultured rat cortical astrocytes.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adrenergic Agonists; Alzheimer Disease; Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Muscarinic Antagonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptor Cross-Talk; Receptors, Muscarinic; Receptors, Nicotinic; Receptors, Purinergic | 2002 |
Administration of adenosine receptor agonists or antagonists after controlled cortical impact in mice: effects on function and histopathology.
Topics: 2-Chloroadenosine; Adenosine; Animals; Brain Injuries; Cell Count; Cerebral Cortex; Hand Strength; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Neuroprotective Agents; Postural Balance; Psychomotor Performance; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Xanthines | 2002 |
Binding of HTLV-1 virions to T cells occurs by a temperature and calcium-dependent process and is blocked by certain type 2 adenosine receptor antagonists.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antibodies, Monoclonal; Calcium; Cations, Divalent; Cell Line, Transformed; Human T-lymphotropic virus 1; Humans; Kinetics; Membrane Microdomains; Phenethylamines; Purinergic P1 Receptor Agonists; Quinazolines; T-Lymphocytes; Thermodynamics; Triazoles | 2003 |
Gastric ulcers and pancreatitis in rats given 2-chloroadenosine or adenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Pancreatitis; Peptic Ulcer; Rats; Stomach Ulcer | 1954 |
A study of the cardiovascular actions of 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Blood Pressure; Blood Pressure Determination; Cardiovascular System; Congenital Abnormalities | 1959 |
The effect of ouabain on the heart block produced in the guinea pig by 2-chloroadenosine.
Topics: 2-Chloroadenosine; Adenosine; Guinea Pigs; Heart Block; Ouabain; Strophanthins | 1959 |
INHIBITION BY ADENOSINE AND BY 2-CHLOROADENOSINE OF THE FORMATION AND EMBOLIZATION OF PLATELET THROMBI.
Topics: 2-Chloroadenosine; Adenosine; Blood Platelets; Nucleosides; Pharmacology; Rabbits; Research; Thrombosis; Wounds and Injuries | 1964 |
Effect of taurine deficiency on adenosine receptor-mediated relaxation of the rat aorta.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; beta-Alanine; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phenylephrine; Rats; Rats, Inbred WKY; Receptors, Purinergic P1; Taurine; Triazines; Triazoles; Vasoconstrictor Agents; Vasodilator Agents | 2003 |
Differential modulation of ATP-induced calcium signalling by A1 and A2 adenosine receptors in cultured cortical astrocytes.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Cyclic AMP; Down-Regulation; Purinergic P1 Receptor Agonists; Rats; Receptors, Purinergic P1 | 2004 |
Exaggerated response to adenosine in kidneys from high salt-fed rats: role of epoxyeicosatrienoic acids.
Topics: 2-Chloroadenosine; 8,11,14-Eicosatrienoic Acid; Adenosine; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Dose-Response Relationship, Drug; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kidney; Male; Perfusion; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Renal Circulation; Sodium, Dietary; Vasodilation | 2005 |
Characterization of the effects of adenosine receptor agonists on cerebral blood flow in uninjured and traumatically injured rat brain using continuous arterial spin-labeled magnetic resonance imaging.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Brain Injuries; Cerebrovascular Circulation; Magnetic Resonance Imaging; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Spin Labels; Trauma Severity Indices | 2005 |
Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Carcinoma, Lewis Lung; Cell Line, Tumor; Cyclic AMP; Cytotoxicity, Immunologic; Fas Ligand Protein; Female; GTP-Binding Protein alpha Subunits, Gs; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Activation; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Signal Transduction | 2005 |
Hypoxia-induced desensitization and internalization of adenosine A1 receptors in the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Disease Models, Animal; Endocytosis; Excitatory Postsynaptic Potentials; Hippocampus; Hypoxia-Ischemia, Brain; Male; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Synaptic Transmission; Theophylline; Xanthines | 2006 |
Effects of adenosine deaminase and A1 receptor deficiency in normoxic and ischaemic mouse hearts.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Deaminase; Animals; Dose-Response Relationship, Drug; Heart Rate; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Myocardial Contraction; Myocardial Ischemia; Myocardium; Perfusion; Receptor, Adenosine A1; Vasodilator Agents; Ventricular Pressure | 2006 |
Nitric oxide mediates interactions between GABAA receptors and adenosine A1 receptors in the rat hippocampus.
Topics: 2-Chloroadenosine; Adenosine; Animals; Bicuculline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Guanylate Cyclase; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Penicillamine; Quinoxalines; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, GABA-A; Synaptic Transmission | 2006 |
Adenosine-mediated inhibition of the cytotoxic activity and cytokine production by activated natural killer cells.
Topics: 2-Chloroadenosine; Adenosine; Animals; Cyclic AMP-Dependent Protein Kinases; Cytokines; Enzyme Activation; Female; Isoenzymes; Killer Cells, Lymphokine-Activated; Mice; Mice, Inbred C57BL | 2006 |
Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Receptor, Adenosine A1; Theophylline; Time Factors; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2007 |
Determination of adenosine effects and adenosine receptors in murine corpus cavernosum.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Atropine; Bretylium Tosylate; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Penile Erection; Phenylephrine; Prazosin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Triazoles | 2007 |
Inhibition of cytokine production and cytotoxic activity of human antimelanoma specific CD8+ and CD4+ T lymphocytes by adenosine-protein kinase A type I signaling.
Topics: 2-Chloroadenosine; Adenosine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclic AMP-Dependent Protein Kinases; Cytokines; Cytotoxicity, Immunologic; Humans; Melanoma; Receptor, Adenosine A2A; Signal Transduction | 2007 |
ATP modulates the release of noradrenaline through two different prejunctional receptors on the adrenergic nerves of rat prostate.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Norepinephrine; Presynaptic Terminals; Prostate; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Presynaptic; Receptors, Purinergic P2; Suramin; Sympathetic Nervous System; Thionucleotides; Xanthines | 2007 |
Adenosine A1 receptors regulate lipolysis and lipogenesis in mouse adipose tissue-interactions with insulin.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Agonists; Adenosine Deaminase; Adipose Tissue; Animals; Body Weight; Cyclic AMP; Dose-Response Relationship, Drug; Glucose; Insulin; Lipids; Lipogenesis; Lipolysis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Norepinephrine; Receptor, Adenosine A1; Signal Transduction | 2008 |
Inhibition of ATP synthase by chlorinated adenosine analogue.
Topics: 2-Chloroadenosine; Adenosine; Antineoplastic Agents; ATP Synthetase Complexes; Glycolysis; Halogenation; Hydrolysis; Models, Molecular; Oxygen Consumption; Protein Binding; Protein Conformation | 2009 |
Adenosine regulation of microtubule dynamics in cardiac hypertrophy.
Topics: 2-Chloroadenosine; 5'-Nucleotidase; Adenosine; Animals; Cardiomegaly; Cells, Cultured; Colchicine; Disease Models, Animal; Mice; Mice, Inbred BALB C; Mice, Knockout; Microtubules; Myocardial Contraction; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Tubulin; Tubulin Modulators | 2009 |
Endogenous adenosine selectively modulates oxidant stress via the A1 receptor in ischemic hearts.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Agonists; Animals; Cholesterol; Cholesterol Esters; Chromatography, High Pressure Liquid; Glutathione; Heme Oxygenase-1; Hydroxides; L-Lactate Dehydrogenase; Lipid Peroxides; Male; Mice; Myocardial Reperfusion Injury; Oxidation-Reduction; Oxidative Stress; Polymerase Chain Reaction; Receptor, Adenosine A1; Vitamin E | 2009 |
Predominance of adenosine excitatory over inhibitory effects on transmission at the neuromuscular junction of infant rats.
Topics: 2-Chloroadenosine; Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Diaphragm; Excitatory Postsynaptic Potentials; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Ligands; Male; Miniature Postsynaptic Potentials; Neuromuscular Junction; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Tubercidin | 2010 |
Estimation of endogenous adenosine activity at adenosine receptors in guinea-pig ileum using a new pharmacological method.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dilazep; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Male; Muscle Contraction; Receptors, Purinergic P1; Synaptic Transmission; Theophylline; Vasodilator Agents | 2010 |
Quantitative analysis of adenosine using liquid chromatography/atmospheric pressure chemical ionization-tandem mass spectrometry (LC/APCI-MS/MS).
Topics: 2-Chloroadenosine; Adenosine; Cells, Cultured; Chromatography, Liquid; Culture Media; Drug Stability; Humans; Neurons; Reproducibility of Results; Sensitivity and Specificity; Stem Cells; Tandem Mass Spectrometry | 2010 |
Characteristics of tolerance in the guinea pig ileum produced by chronic in vivo exposure to opioid versus cannabinoid agonists.
Topics: 2-Chloroadenosine; Adenosine; Analgesics, Opioid; Animals; Benzoxazines; Cannabinoids; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; Ileum; Morphine; Morpholines; Muscle Contraction; Naphthalenes; Receptors, Opioid, mu | 2010 |
Characterization of the Drosophila adenosine receptor: the effect of adenosine analogs on cAMP signaling in Drosophila cells and their utility for in vivo experiments.
Topics: 2-Chloroadenosine; Adenosine; Amino Acid Sequence; Amino Acids; Animals; Calcium; Calcium Signaling; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Drosophila; Humans; Molecular Sequence Data; Pyrimidines; Real-Time Polymerase Chain Reaction; Receptors, Purinergic P1; Signal Transduction; Survival; Triazoles | 2012 |
Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms.
Topics: 2-Chloroadenosine; Adenosine; Cell Line, Tumor; Clinical Trials, Phase I as Topic; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucosephosphate Dehydrogenase; Hematologic Neoplasms; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Multiple Myeloma; Neoplasm Proteins; Pentose Phosphate Pathway; RNA, Neoplasm | 2012 |
Characterization of biosynthetic genes of ascamycin/dealanylascamycin featuring a 5'-O-sulfonamide moiety in Streptomyces sp. JCM9888.
Topics: 2-Chloroadenosine; Adenosine; Genes, Bacterial; Molecular Sequence Data; Multigene Family; Streptomyces; Sulfonamides | 2014 |
Adenosine Attenuates Human Coronary Artery Smooth Muscle Cell Proliferation by Inhibiting Multiple Signaling Pathways That Converge on Cyclin D.
Topics: 2-Chloroadenosine; Adenosine; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclin D; Cyclin-Dependent Kinase Inhibitor p27; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; Male; Myocytes, Smooth Muscle; Rats, Inbred WKY; Receptor, Adenosine A1; Receptor, Adenosine A2B; RNA Interference; S-Phase Kinase-Associated Proteins; Signal Transduction | 2015 |
Adenosine Attenuates Aortic Smooth Muscle Cell Calcification through A
Topics: 2-Chloroadenosine; Adenosine; Alkaline Phosphatase; Aorta; Calcinosis; Humans; Myocytes, Smooth Muscle; Oncostatin M; Receptor, Adenosine A3; Signal Transduction | 2019 |
8-azaadenosine and 8-chloroadenosine are not selective inhibitors of ADAR.
Topics: 2-Chloroadenosine; Adenosine; Interferon Type I | 2021 |