Page last updated: 2024-08-20

2-chloroadenosine and 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

2-chloroadenosine has been researched along with 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobson, KA; van Galen, PJ; Williams, M1
Jacobson, KA; Kim, J; Schöneberg, T; van Rhee, AM; Wess, J1
Bertin, B; Freissmuth, M; Hohenegger, M; Jockers, R; Linder, ME; Marullo, S; Nanoff, C; Strosberg, AD1
Figler, H; Jin, X; Linden, J; Robeva, AS; Thai, T1
Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW1
Barak, D; Chen, A; Gao, ZG; Jacobson, KA; Kim, SA; Lee, K; Liang, BT; Link, A; Rompaey, PV; van Calenbergh, S1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1

Reviews

1 review(s) available for 2-chloroadenosine and 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

ArticleYear
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
    Journal of medicinal chemistry, 1992, Feb-07, Volume: 35, Issue:3

    Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship

1992

Other Studies

7 other study(ies) available for 2-chloroadenosine and 8-(4-((2-aminoethyl)aminocarbonylmethyloxy)phenyl)-1,3-dipropylxanthine

ArticleYear
Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.
    The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23

    Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Purinergic P1; Structure-Activity Relationship

1995
Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.
    The Journal of biological chemistry, 1994, Dec-23, Volume: 269, Issue:51

    Topics: Animals; Base Sequence; Brain; Cattle; DNA Primers; Escherichia coli; GTP-Binding Proteins; Humans; Molecular Sequence Data; Protein Binding; Receptors, Purinergic P1; Recombinant Proteins; Species Specificity

1994
Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
    Molecular pharmacology, 1999, Volume: 56, Issue:4

    Topics: Animals; Anti-Asthmatic Agents; Blotting, Western; Calcium; Cell Degranulation; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Humans; Kidney; Mast Cells; Purinergic P1 Receptor Agonists; Radioligand Assay; Receptor, Adenosine A2B; Receptors, Purinergic P1; Theophylline; Type C Phospholipases; Xanthines

1999
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
    Molecular pharmacology, 2000, Volume: 58, Issue:6

    Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine

2000
Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.
    Journal of medicinal chemistry, 2001, Nov-22, Volume: 44, Issue:24

    Topics: Adenosine; Amines; Animals; Cell Line; Cerebral Cortex; Cyclic AMP; GTP-Binding Proteins; Humans; In Vitro Techniques; Ligands; Models, Molecular; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009