Page last updated: 2024-09-23

adenosine 2',3'-ribo-epoxide

Description

adenosine 2',3'-ribo-epoxide: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID72252
CHEMBL ID2032007
SCHEMBL ID5471536
MeSH IDM0048959

Synonyms (16)

Synonym
2',3'-epoxya down
2',3'-epoxyadenosine down
2627-64-7
[(1r,2r,4r,5r)-4-(6-aminopurin-9-yl)-3,6-dioxabicyclo[3.1.0]hexan-2-yl]methanol
CHEMBL2032007
adenosine, 2',3'-anhydro-
adenosine 2',3'-ribo-epoxide
9-(2,3-anhydro-beta-d-ribofuranosyl)adenine
2',3'-anhydroadenosine
SCHEMBL5471536
RANSNKOSWWZYEJ-KQYNXXCUSA-N
A855616
9-(2,3-anhydropentofuranosyl)-9h-purin-6-amine
DTXSID70949134
[(1r,2r,4r,5r)-4-(6-amino-9h-purin-9-yl)-3,6-dioxabicyclo[3.1.0]hexan-2-yl]methanol
((1r,2r,4r,5r)-4-(6-amino-9h-purin-9-yl)-3,6-dioxabicyclo[3.1.0]hexan-2-yl)methanol

Bioassays (4)

Assay IDTitleYearJournalArticle
AID662565Growth inhibition of Trichomonas vaginalis T1 at 100 uM after 24 hrs by hemocytometry2012Bioorganic & medicinal chemistry letters, Jun-15, Volume: 22, Issue:12
S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.
AID1065714Trypanocidal activity against bloodstream stage of Trypanosoma brucei brucei AnTat1.1E after 72 hrs by WST-1 assay2013Journal of medicinal chemistry, Dec-27, Volume: 56, Issue:24
Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.
AID81438Dose required to inhibit cytopathic effect of human immunodeficiency virus replication in MT-4 cells.1988Journal of medicinal chemistry, Oct, Volume: 31, Issue:10
Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides.
AID81069Cytotoxic dose required to reduce the viability of normal uninfected MT-4 cells.1988Journal of medicinal chemistry, Oct, Volume: 31, Issue:10
Synthesis and anti-HIV activity of different sugar-modified pyrimidine and purine nucleosides.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]