Page last updated: 2024-11-04

sumatriptan and Rosacea

sumatriptan has been researched along with Rosacea in 1 studies

Sumatriptan: A serotonin agonist that acts selectively at 5HT1 receptors. It is used in the treatment of MIGRAINE DISORDERS.
sumatriptan : A sulfonamide that consists of N,N-dimethyltryptamine bearing an additional (N-methylsulfamoyl)methyl substituent at position 5. Selective agonist for a vascular 5-HT1 receptor subtype (probably a member of the 5-HT1D family). Used (in the form of its succinate salt) for the acute treatment of migraine with or without aura in adults.

Rosacea: A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).

Research Excerpts

ExcerptRelevanceReference
"We established a clinical experimental model of rosacea features and showed that sumatriptan was able to attenuate PACAP38-induced rosacea flushing and edema."9.41Infusion of Pituitary Adenylate Cyclase-Activating Polypeptide-38 in Patients with Rosacea Induces Flushing and Facial Edema that Can Be Attenuated by Sumatriptan. ( Ashina, M; Christensen, CE; Coskun, H; Egeberg, A; Ghanizada, H; Thyssen, JP; Wienholtz, NKF; Zhang, DG, 2021)
"We established a clinical experimental model of rosacea features and showed that sumatriptan was able to attenuate PACAP38-induced rosacea flushing and edema."5.41Infusion of Pituitary Adenylate Cyclase-Activating Polypeptide-38 in Patients with Rosacea Induces Flushing and Facial Edema that Can Be Attenuated by Sumatriptan. ( Ashina, M; Christensen, CE; Coskun, H; Egeberg, A; Ghanizada, H; Thyssen, JP; Wienholtz, NKF; Zhang, DG, 2021)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Wienholtz, NKF1
Christensen, CE1
Coskun, H1
Zhang, DG1
Ghanizada, H1
Egeberg, A1
Thyssen, JP1
Ashina, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Investigation of PACAP38-induced Headache and Rosacea-like Symptoms in Patients With Rosacea[NCT03878784]38 participants (Actual)Interventional2018-11-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for sumatriptan and Rosacea

ArticleYear
Infusion of Pituitary Adenylate Cyclase-Activating Polypeptide-38 in Patients with Rosacea Induces Flushing and Facial Edema that Can Be Attenuated by Sumatriptan.
    The Journal of investigative dermatology, 2021, Volume: 141, Issue:7

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Edema; Face; Female; Flushing; Humans; Infusions, In

2021