Page last updated: 2024-11-06

tromantadine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID64377
CHEMBL ID3085149
CHEMBL ID3989506
CHEBI ID135163
SCHEMBL ID148486
MeSH IDM0045285

Synonyms (40)

Synonym
n-(1-adamantyl)-2-(2-dimethylaminoethyloxy)acetamide
n-1-adamantyl-2-[2-(dimethylamino)ethoxy]acetamide
53783-83-8
tromantadine
tromantadine (inn)
D07199
2-(2-(dimethylamino)ethoxy)-n-tricyclo(3.3.1.1(3,7))dec-1-ylacetamide
n-1-adamantyl-2-((2-dimethylamino)ethoxy)acetamide
2-(2-(dimethylamino)ethoxy)-n-tricyclo(3.3.1.13,7)dec-1-ylacetamide
einecs 258-770-0
tromantadina [inn-spanish]
tromantadin
tromantadine [inn:dcf]
n-(tricyclo(3.3.1.1(3,7))decyl)-2-(2-dimethylaminoethoxy)acetamid
tromantadinum [inn-latin]
acetamide, 2-(2-(dimethylamino)ethoxy)-n-tricyclo(3.3.1.13,7)dec-1-yl-
tromantadinum [latin]
n-1-adamantyl-2-(2-(dimethylamino)ethoxy)acetamide
CHEBI:135163
h191jfg8wa ,
tromantadina
unii-h191jfg8wa
tromantadinum
CHEMBL3085149
SCHEMBL148486
tromantadine [who-dd]
tromantadine [mi]
tromantadine [inn]
tromantadine [ii]
DTXSID00202062
n-(1-adamantyl)-2-[2-(dimethylamino)ethoxy]acetamide
AKOS030573341
HY-U00124
CS-7161
Q4463719
DB13288
CHEMBL3989506
n-(adamantan-1-yl)-2-(2-(dimethylamino)ethoxy)acetamide
EN300-22285451
n-(adamantan-1-yl)-2-[2-(dimethylamino)ethoxy]acetamide

Research Excerpts

Overview

Tromantadine is a topical antiviral agent derived from amantadines.

ExcerptReferenceRelevance
"Tromantadine is a topical antiviral agent derived from amantadine. "( Allergic contact dermatitis from tromantadine.
Antépara, I; Gamboa, PM; Jáuregui, I; Urrutia, I,
)
1.86
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
secondary carboxamideA carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1).
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID700831Drug elimination in po dosed human assessed as unchanged compound level2011European journal of medicinal chemistry, Jun, Volume: 46, Issue:6
The many faces of the adamantyl group in drug design.
AID700830Ratio of drug level in liver to blood in human2011European journal of medicinal chemistry, Jun, Volume: 46, Issue:6
The many faces of the adamantyl group in drug design.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (42)

TimeframeStudies, This Drug (%)All Drugs %
pre-199033 (78.57)18.7374
1990's5 (11.90)18.2507
2000's1 (2.38)29.6817
2010's3 (7.14)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 36.08

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index36.08 (24.57)
Research Supply Index4.03 (2.92)
Research Growth Index4.23 (4.65)
Search Engine Demand Index44.62 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (36.08)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials9 (19.57%)5.53%
Reviews4 (8.70%)6.00%
Case Studies10 (21.74%)4.05%
Observational0 (0.00%)0.25%
Other23 (50.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]