spironolactone has been researched along with Rosacea in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Rosacea: A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To observe the clinical efficacy of Chibixiao Recipe (CBX) in combination with minocycline and spironolactone in treating rosacea in females." | 9.12 | Effect of treatment of rosacea in females by Chibixiao Recipe in combination with minocycline and spironolactone. ( Guo, W; Yu, TG; Zheng, YZ; Zhu, JT, 2006) |
| "Spironolactone at 50 mg/day was orally administered for four weeks to 13 male patients with rosacea in order to observe its clinical effectiveness." | 7.68 | Oral spironolactone therapy in male patients with rosacea. ( Aizawa, H; Niimura, M, 1992) |
| "To observe the clinical efficacy of Chibixiao Recipe (CBX) in combination with minocycline and spironolactone in treating rosacea in females." | 5.12 | Effect of treatment of rosacea in females by Chibixiao Recipe in combination with minocycline and spironolactone. ( Guo, W; Yu, TG; Zheng, YZ; Zhu, JT, 2006) |
| "Spironolactone at 50 mg/day was orally administered for four weeks to 13 male patients with rosacea in order to observe its clinical effectiveness." | 3.68 | Oral spironolactone therapy in male patients with rosacea. ( Aizawa, H; Niimura, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spoendlin, J | 1 |
| Voegel, JJ | 1 |
| Jick, SS | 1 |
| Meier, CR | 1 |
| Yu, TG | 1 |
| Zheng, YZ | 1 |
| Zhu, JT | 1 |
| Guo, W | 1 |
| Aizawa, H | 1 |
| Niimura, M | 1 |
1 trial available for spironolactone and Rosacea
| Article | Year |
|---|---|
Effect of treatment of rosacea in females by Chibixiao Recipe in combination with minocycline and spironolactone.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Medicine, Chinese Traditional; Middle Aged; Minocy | 2006 |
2 other studies available for spironolactone and Rosacea
| Article | Year |
|---|---|
Spironolactone may reduce the risk of incident rosacea.
Topics: Databases, Factual; Diuretics; Female; Humans; Incidence; Male; Risk Factors; Rosacea; Spironolacton | 2013 |
Oral spironolactone therapy in male patients with rosacea.
Topics: Administration, Oral; Adult; Gonadal Steroid Hormones; Humans; Male; Middle Aged; Rosacea; Sebaceous | 1992 |