Page last updated: 2024-10-25

clonidine and Rosacea

clonidine has been researched along with Rosacea in 6 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Rosacea: A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).

Research Excerpts

ExcerptRelevanceReference
"The effects of clonidine hydrochloride, an agent effective in suppressing other types of flushing reactions, were investigated in patients with erythematotelangiectatic rosacea."9.05Effect of subdepressor clonidine on flushing reactions in rosacea. Change in malar thermal circulation index during provoked flushing reactions. ( Wilkin, JK, 1983)
"The effects of clonidine hydrochloride, an agent effective in suppressing other types of flushing reactions, were investigated in patients with erythematotelangiectatic rosacea."5.05Effect of subdepressor clonidine on flushing reactions in rosacea. Change in malar thermal circulation index during provoked flushing reactions. ( Wilkin, JK, 1983)
"Flushing in rosacea has been investigated by means of (a) pharmacological inhibition of some possible chemical mediators and (b) titration of bradykinin as a possible effector directly in the blood."3.66Flushing in rosacea: a possible mechanism. ( Cipriani, C; Divano, C; Guarrera, M; Parodi, A; Rebora, A, 1982)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wilkin, JK1
Guarrera, M1
Parodi, A1
Cipriani, C1
Divano, C1
Rebora, A1
Van Landuyt, H1
Joubert-Lequain, I1
Humbert, P1
Lucas, A1
Drobacheff, C1
Mercier, M1
Laurent, R1
Cunliffe, WJ1
Dodman, B1
Binner, JG1
Grosshans, E1

Trials

4 trials available for clonidine and Rosacea

ArticleYear
Effect of subdepressor clonidine on flushing reactions in rosacea. Change in malar thermal circulation index during provoked flushing reactions.
    Archives of dermatology, 1983, Volume: 119, Issue:3

    Topics: Clonidine; Face; Female; Humans; Male; Rosacea; Skin Temperature

1983
[Treatment of rosacea. Clonidine (0.075 mg per day) versus placebo (initial results)].
    Annales de dermatologie et de venereologie, 1997, Volume: 124, Issue:10

    Topics: Adrenergic alpha-Agonists; Clonidine; Humans; Placebos; Rosacea

1997
Clonidine and facial flushing in rosacea.
    British medical journal, 1977, Jan-08, Volume: 1, Issue:6053

    Topics: Clinical Trials as Topic; Clonidine; Drug Evaluation; Erythema; Face; Humans; Rosacea

1977
[Rosacea].
    Presse medicale (Paris, France : 1983), 1988, Dec-17, Volume: 17, Issue:45

    Topics: Body Temperature; Clinical Trials as Topic; Clonidine; Female; Humans; Isotretinoin; Male; Metronida

1988

Other Studies

2 other studies available for clonidine and Rosacea

ArticleYear
INN Common stem: -onidine.
    Prescrire international, 2017, Volume: 26, Issue:181

    Topics: Adrenergic alpha-2 Receptor Agonists; Antimalarials; Brimonidine Tartrate; Cinchona Alkaloids; Cloni

2017
Flushing in rosacea: a possible mechanism.
    Archives of dermatological research, 1982, Volume: 272, Issue:3-4

    Topics: Adult; Aspirin; Body Temperature; Bradykinin; Clonidine; Epinephrine; Face; Female; Humans; Indometh

1982