pirenperone has been researched along with Fragile X Syndrome in 1 studies
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of pirenperone increased the expression level of Fmr1 gene." | 5.72 | Pirenperone relieves the symptoms of fragile X syndrome in Fmr1 knockout mice. ( Ahn, T; Gonzales, EL; Jeon, SJ; Kim, Y; Remonde, CG; Shin, CY; Shin, D, 2022) |
| "Treatment of pirenperone increased the expression level of Fmr1 gene." | 1.72 | Pirenperone relieves the symptoms of fragile X syndrome in Fmr1 knockout mice. ( Ahn, T; Gonzales, EL; Jeon, SJ; Kim, Y; Remonde, CG; Shin, CY; Shin, D, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, Y | 2 |
| Jeon, SJ | 2 |
| Gonzales, EL | 2 |
| Shin, D | 2 |
| Remonde, CG | 2 |
| Ahn, T | 2 |
| Shin, CY | 2 |
1 other study available for pirenperone and Fragile X Syndrome
| Article | Year |
|---|---|
Pirenperone relieves the symptoms of fragile X syndrome in Fmr1 knockout mice.
Topics: Animals; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Mice; Mic | 2022 |
Pirenperone relieves the symptoms of fragile X syndrome in Fmr1 knockout mice.
Topics: Animals; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Mice; Mic | 2022 |
Pirenperone relieves the symptoms of fragile X syndrome in Fmr1 knockout mice.
Topics: Animals; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Mice; Mic | 2022 |
Pirenperone relieves the symptoms of fragile X syndrome in Fmr1 knockout mice.
Topics: Animals; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Mice; Mic | 2022 |