chlorzoxazone has been researched along with Fragile X Syndrome in 1 studies
Chlorzoxazone: A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
chlorzoxazone : A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazol-2-ol in which the hydrogen atom at position 5 is substituted by chlorine. A centrally acting muscle relaxant with sedative properties, it is used for the symptomatic treatment of painful muscle spasm.
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mechanisms underlying hyperacusis in FXS are still largely unknown and effective therapies are lacking." | 1.91 | Hyperacusis in the Adult ( Bouleau, Y; Dulon, D; Ferraguto, C; Peineau, T; Pietropaolo, S, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferraguto, C | 1 |
| Bouleau, Y | 1 |
| Peineau, T | 1 |
| Dulon, D | 1 |
| Pietropaolo, S | 1 |
1 other study available for chlorzoxazone and Fragile X Syndrome
| Article | Year |
|---|---|
Hyperacusis in the Adult
Topics: Animals; Auditory Pathways; Chlorzoxazone; Disease Models, Animal; Fragile X Mental Retardation Prot | 2023 |