azacitidine and Fragile X Syndrome

azacitidine has been researched along with Fragile X Syndrome in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (16.67)	18.7374
1990's	2 (16.67)	18.2507
2000's	4 (33.33)	29.6817
2010's	4 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chiurazzi, P; Tabolacci, E	1
Kumari, D; Usdin, K	1
Nielsen, AL; Sølvsten, C	1
Bar-Nur, O; Benvenisty, N; Caspi, I	1
Chiurazzi, P; Neri, G; Oostra, B; Pietrobono, R; Pomponi, MG; Tabolacci, E	1
Ceman, S; Coffee, B; Reines, D; Warren, ST; Zhang, F	1
Chiurazzi, P; Moscato, U; Neri, G; Oostra, BA; Pietrobono, R; Tabolacci, E	1
Biacsi, R; Kumari, D; Usdin, K	1
Dev, VG; Mixon, JC	1
Coffee, B; Reines, D; Warren, ST; Zhang, F	1
Bakker, CE; Chiurazzi, P; Neri, G; Oostra, BA; Pietrobono, R; Pomponi, MG	1
Berger, C; Coyle-Morris, J; Gemmill, RM; Glover, TW; Pearce-Birge, L	1

Reviews

1 review(s) available for azacitidine and Fragile X Syndrome

Article	Year
Epigenetics, fragile X syndrome and transcriptional therapy. American journal of medical genetics. Part A, 2013, Volume: 161A, Issue:11 Topics: Animals; Azacitidine; Chromatin Assembly and Disassembly; DNA Methylation; Epigenesis, Genetic; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histones; Humans; RNA; Transcription, Genetic	2013

Article

Year

Epigenetics, fragile X syndrome and transcriptional therapy.

American journal of medical genetics. Part A, 2013, Volume: 161A, Issue:11

Topics: Animals; Azacitidine; Chromatin Assembly and Disassembly; DNA Methylation; Epigenesis, Genetic; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Histone Deacetylase Inhibitors; Histones; Humans; RNA; Transcription, Genetic

2013

Other Studies

11 other study(ies) available for azacitidine and Fragile X Syndrome

Article	Year
Polycomb group complexes are recruited to reactivated FMR1 alleles in Fragile X syndrome in response to FMR1 transcription. Human molecular genetics, 2014, Dec-15, Volume: 23, Issue:24 Topics: Alleles; Azacitidine; Cell Line; Decitabine; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Histones; Humans; Lymphocytes; Male; Naphthalenes; Polycomb Repressive Complex 2; Pyrones; RNA, Messenger; RNA, Small Interfering; Sirtuin 1; Transcription, Genetic	2014
FMR1 CGG repeat lengths mediate different regulation of reporter gene expression in comparative transient and locus specific integration assays. Gene, 2011, Oct-15, Volume: 486, Issue:1-2 Topics: 5' Untranslated Regions; Azacitidine; Base Sequence; Decitabine; DNA Primers; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Gene Silencing; Genes, Reporter; HEK293 Cells; Humans; Male; Mutation; RNA, Messenger; Transfection; Trinucleotide Repeat Expansion; Trinucleotide Repeats	2011
Molecular analysis of FMR1 reactivation in fragile-X induced pluripotent stem cells and their neuronal derivatives. Journal of molecular cell biology, 2012, Volume: 4, Issue:3 Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cell Differentiation; Cells, Cultured; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Fragile X Mental Retardation Protein; Fragile X Syndrome; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Induced Pluripotent Stem Cells; Mice; Neurons	2012
Quantitative analysis of DNA demethylation and transcriptional reactivation of the FMR1 gene in fragile X cells treated with 5-azadeoxycytidine. Nucleic acids research, 2002, Jul-15, Volume: 30, Issue:14 Topics: Azacitidine; Base Sequence; Cell Line; CpG Islands; Decitabine; DNA; DNA Methylation; DNA Modification Methylases; Enzyme Inhibitors; Fragile X Mental Retardation Protein; Fragile X Syndrome; Humans; Male; Molecular Sequence Data; Nerve Tissue Proteins; Promoter Regions, Genetic; RNA-Binding Proteins; RNA, Messenger; Sequence Analysis, DNA	2002
Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome. American journal of human genetics, 2002, Volume: 71, Issue:4 Topics: Acetylation; Alleles; Azacitidine; Decitabine; DNA Methylation; Fragile X Mental Retardation Protein; Fragile X Syndrome; Heterochromatin; Histones; Humans; Lysine; Nerve Tissue Proteins; RNA-Binding Proteins; Transcriptional Activation; Trinucleotide Repeats; Tumor Cells, Cultured	2002
Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments. European journal of human genetics : EJHG, 2005, Volume: 13, Issue:5 Topics: Acetylation; Acetylcarnitine; Azacitidine; Cell Line; Chromatin Immunoprecipitation; Decitabine; DNA Methylation; Epigenesis, Genetic; Exons; Fragile X Mental Retardation Protein; Fragile X Syndrome; Histones; Humans; Male; Nerve Tissue Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA-Binding Proteins	2005
SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome. PLoS genetics, 2008, Mar-07, Volume: 4, Issue:3 Topics: Alleles; Azacitidine; Base Sequence; Cell Line; Decitabine; DNA Methylation; DNA Primers; Enzyme Inhibitors; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Silencing; Histones; Humans; Hydroxamic Acids; Models, Biological; Mutation; Naphthalenes; Niacinamide; Promoter Regions, Genetic; Pyrones; Sirtuin 1; Sirtuins; Trinucleotide Repeat Expansion	2008
Fragile X expression is decreased by 5-azacytidine and S-adenosylhomocysteine. American journal of human genetics, 1983, Volume: 35, Issue:6 Topics: Azacitidine; Cell Line; Culture Media; DNA; Dose-Response Relationship, Drug; Floxuridine; Fragile X Syndrome; Homocysteine; Humans; Karyotyping; Methionine; Methylation; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Chromosome Aberrations	1983
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells. Nature genetics, 1999, Volume: 22, Issue:1 Topics: Acetylation; Acetyltransferases; Azacitidine; Cells, Cultured; Chromatin; Decitabine; DNA; Enzyme Inhibitors; Fragile X Mental Retardation Protein; Fragile X Syndrome; Histone Acetyltransferases; Histones; Humans; Hydroxamic Acids; Male; Nerve Tissue Proteins; Protein Binding; RNA-Binding Proteins; Saccharomyces cerevisiae Proteins; Transcription, Genetic	1999
Synergistic effect of histone hyperacetylation and DNA demethylation in the reactivation of the FMR1 gene. Human molecular genetics, 1999, Volume: 8, Issue:12 Topics: Acetylation; Azacitidine; Base Sequence; Cell Line; Decitabine; DNA Methylation; DNA Primers; Enzyme Inhibitors; Fragile X Mental Retardation Protein; Fragile X Syndrome; Histone Deacetylase Inhibitors; Histones; Humans; Male; Nerve Tissue Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins	1999
DNA demethylation induced by 5-azacytidine does not affect fragile X expression. American journal of human genetics, 1986, Volume: 38, Issue:3 Topics: Azacitidine; Cell Line; Chromosome Fragility; DNA; DNA Restriction Enzymes; Fragile X Syndrome; Gene Expression Regulation; Genetic Markers; Humans; Lymphocytes; Male; Methylation; X Chromosome	1986