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trimethoprim and Fragile X Syndrome

trimethoprim has been researched along with Fragile X Syndrome in 3 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santos, M1
Morizon, G1
Hecht, F1
Glover, TW1
McLean, DA1
Faed, MJ1

Other Studies

3 other studies available for trimethoprim and Fragile X Syndrome

ArticleYear
[Fragile X chromosome syndrome: a chromosomal defect associated with mental retardation].
    Revista medica de Chile, 1983, Volume: 111, Issue:6

    Topics: Folic Acid; Fragile X Syndrome; Humans; Intellectual Disability; Sex Chromosome Aberrations; Trimeth

1983
Antibiotics containing trimethoprim and the fragile X chromosome.
    The New England journal of medicine, 1983, Feb-03, Volume: 308, Issue:5

    Topics: Anti-Bacterial Agents; Child, Preschool; Folic Acid; Folic Acid Antagonists; Fragile X Syndrome; Hum

1983
Improved fragile site detection with trimethoprim.
    Human genetics, 1990, Volume: 85, Issue:2

    Topics: Chromosome Fragile Sites; Chromosome Fragility; Female; Fragile X Syndrome; Humans; Male; Sex Chromo

1990