trimethoprim has been researched along with Fragile X Syndrome in 3 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (66.67) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Santos, M | 1 |
Morizon, G | 1 |
Hecht, F | 1 |
Glover, TW | 1 |
McLean, DA | 1 |
Faed, MJ | 1 |
3 other studies available for trimethoprim and Fragile X Syndrome
Article | Year |
---|---|
[Fragile X chromosome syndrome: a chromosomal defect associated with mental retardation].
Topics: Folic Acid; Fragile X Syndrome; Humans; Intellectual Disability; Sex Chromosome Aberrations; Trimeth | 1983 |
Antibiotics containing trimethoprim and the fragile X chromosome.
Topics: Anti-Bacterial Agents; Child, Preschool; Folic Acid; Folic Acid Antagonists; Fragile X Syndrome; Hum | 1983 |
Improved fragile site detection with trimethoprim.
Topics: Chromosome Fragile Sites; Chromosome Fragility; Female; Fragile X Syndrome; Humans; Male; Sex Chromo | 1990 |