clonidine has been researched along with Fragile X Syndrome in 5 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pharmacological treatment of epilepsy is needed whenever epilepsy occurs." | 1.31 | [Medical treatment of fragile X syndrome]. ( Artigas-Pallarés, J; Brun-Gasca, C, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wrenn, CC | 2 |
| French, E | 1 |
| Baker, D | 1 |
| McCallian, R | 1 |
| Kirk, R | 1 |
| Reilly, MP | 1 |
| Valdovinos, MG | 2 |
| Heitzer, AM | 1 |
| Roth, AK | 1 |
| Nawrocki, L | 1 |
| Hall, SS | 1 |
| Artigas-Pallarés, J | 1 |
| Brun-Gasca, C | 1 |
| Hagerman, R | 1 |
1 review available for clonidine and Fragile X Syndrome
| Article | Year |
|---|---|
Treatments for fragile X syndrome: a closer look at the data.
Topics: Acetylcarnitine; Adrenergic alpha-Agonists; Behavior Therapy; Central Nervous System Stimulants; Clo | 2009 |
4 other studies available for clonidine and Fragile X Syndrome
| Article | Year |
|---|---|
Effects of clonidine on progressive ratio schedule performance in Fmr1 knockout mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Conditioning, Operant; Fragile X Mental Re | 2021 |
Effects of clonidine and methylphenidate on motor activity in Fmr1 knockout mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Attention Deficit Disorder with Hyperactivity; Centra | 2015 |
[Medical treatment of fragile X syndrome].
Topics: Adrenergic alpha-Agonists; Anticonvulsants; Antipsychotic Agents; Attention Deficit and Disruptive B | 2001 |
Fragile X: treatment of hyperactivity.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; | 1997 |