choline has been researched along with Fragile X Syndrome in 3 studies
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fragile X syndrome is a learning disability caused by excess of CGG repeats in the 5' untranslated region of the Fragile X gene (FMR1) silencing its transcription and translation." | 5.42 | Brain acetylcholine and choline concentrations and dynamics in a murine model of the Fragile X syndrome: age, sex and region-specific changes. ( Djazayeri, S; Liu, YY; Norman, KM; Roch, M; Scremin, OU, 2015) |
| "Fragile X syndrome is a learning disability caused by excess of CGG repeats in the 5' untranslated region of the Fragile X gene (FMR1) silencing its transcription and translation." | 1.42 | Brain acetylcholine and choline concentrations and dynamics in a murine model of the Fragile X syndrome: age, sex and region-specific changes. ( Djazayeri, S; Liu, YY; Norman, KM; Roch, M; Scremin, OU, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Utine, GE | 1 |
| Akpınar, B | 1 |
| Arslan, U | 1 |
| Kiper, PÖ | 1 |
| Volkan-Salancı, B | 1 |
| Alanay, Y | 1 |
| Aktaş, D | 1 |
| Haliloğlu, G | 1 |
| Oğuz, KK | 1 |
| Boduroğlu, K | 1 |
| Alikaşifoğlu, M | 1 |
| Scremin, OU | 1 |
| Roch, M | 1 |
| Norman, KM | 1 |
| Djazayeri, S | 1 |
| Liu, YY | 1 |
| Kesler, SR | 1 |
| Lightbody, AA | 1 |
| Reiss, AL | 1 |
1 trial available for choline and Fragile X Syndrome
| Article | Year |
|---|---|
Cholinergic dysfunction in fragile X syndrome and potential intervention: a preliminary 1H MRS study.
Topics: Adolescent; Adult; Case-Control Studies; Choline; Cholinesterase Inhibitors; Cognition; Creatine; Do | 2009 |
2 other studies available for choline and Fragile X Syndrome
| Article | Year |
|---|---|
Neurochemical evaluation of brain function with 1H magnetic resonance spectroscopy in patients with fragile X syndrome.
Topics: Aspartic Acid; Brain; Case-Control Studies; Child; Child, Preschool; Choline; Creatine; Fragile X Sy | 2014 |
Brain acetylcholine and choline concentrations and dynamics in a murine model of the Fragile X syndrome: age, sex and region-specific changes.
Topics: Acetylcholine; Aging; Animals; Brain; Choline; Deuterium; Disease Models, Animal; Female; Fragile X | 2015 |