methylphenidate has been researched along with Fragile X Syndrome in 4 studies
Methylphenidate: A central nervous system stimulant used most commonly in the treatment of ATTENTION DEFICIT DISORDER in children and for NARCOLEPSY. Its mechanisms appear to be similar to those of DEXTROAMPHETAMINE. The d-isomer of this drug is referred to as DEXMETHYLPHENIDATE HYDROCHLORIDE.
methylphenidate : A racemate comprising equimolar amounts of the two threo isomers of methyl phenyl(piperidin-2-yl)acetate. A central stimulant and indirect-acting sympathomimetic, is used (generally as the hydrochloride salt) in the treatment of hyperactivity disorders in children and for the treatment of narcolepsy.
methyl phenyl(piperidin-2-yl)acetate : A amino acid ester that is methyl phenylacetate in which one of the hydrogens alpha to the carbonyl group is replaced by a piperidin-2-yl group.
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wrenn, CC | 1 |
| Heitzer, AM | 1 |
| Roth, AK | 1 |
| Nawrocki, L | 1 |
| Valdovinos, MG | 1 |
| Thomson, A | 1 |
| Maltezos, S | 1 |
| Paliokosta, E | 1 |
| Xenitidis, K | 1 |
| Rueda, JR | 1 |
| Ballesteros, J | 1 |
| Tejada, MI | 1 |
| Hagerman, RJ | 1 |
| Miller, LJ | 1 |
| McGrath-Clarke, J | 1 |
| Riley, K | 1 |
| Goldson, E | 1 |
| Harris, SW | 1 |
| Simon, J | 1 |
| Church, K | 1 |
| Bonnell, J | 1 |
| Ognibene, TC | 1 |
| McIntosh, DN | 1 |
2 reviews available for methylphenidate and Fragile X Syndrome
| Article | Year |
|---|---|
Amfetamine for attention deficit hyperactivity disorder in people with intellectual disabilities.
Topics: Amphetamine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child | 2009 |
Systematic review of pharmacological treatments in fragile X syndrome.
Topics: Acetylcarnitine; Dioxoles; Folic Acid; Fragile X Syndrome; Humans; Methylphenidate; Piperidines; Tre | 2009 |
2 other studies available for methylphenidate and Fragile X Syndrome
| Article | Year |
|---|---|
Effects of clonidine and methylphenidate on motor activity in Fmr1 knockout mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Attention Deficit Disorder with Hyperactivity; Centra | 2015 |
Influence of stimulants on electrodermal studies in Fragile X syndrome.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; | 2002 |