serine has been researched along with Fragile X Syndrome in 8 studies
Serine: A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids.
serine : An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group.
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fragile X syndrome is caused by loss of FMR1 protein expression." | 1.31 | Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties. ( Higashijima, K; Ishizuka, A; Siomi, H; Siomi, MC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Nolin, SL | 1 |
| Napoli, E | 1 |
| Flores, A | 1 |
| Hagerman, RJ | 1 |
| Giulivi, C | 1 |
| Bostrom, CA | 1 |
| Majaess, NM | 1 |
| Morch, K | 1 |
| White, E | 1 |
| Eadie, BD | 1 |
| Christie, BR | 1 |
| Kang, JY | 1 |
| Chadchankar, J | 1 |
| Vien, TN | 1 |
| Mighdoll, MI | 1 |
| Hyde, TM | 1 |
| Mather, RJ | 1 |
| Deeb, TZ | 1 |
| Pangalos, MN | 1 |
| Brandon, NJ | 1 |
| Dunlop, J | 1 |
| Moss, SJ | 1 |
| Sharma, A | 1 |
| Hoeffer, CA | 1 |
| Takayasu, Y | 1 |
| Miyawaki, T | 1 |
| McBride, SM | 1 |
| Klann, E | 1 |
| Zukin, RS | 1 |
| Yuskaitis, CJ | 1 |
| Beurel, E | 1 |
| Jope, RS | 1 |
| Coffee, RL | 1 |
| Williamson, AJ | 1 |
| Adkins, CM | 1 |
| Gray, MC | 1 |
| Page, TL | 1 |
| Broadie, K | 1 |
| Ronesi, JA | 1 |
| Collins, KA | 1 |
| Hays, SA | 1 |
| Tsai, NP | 1 |
| Guo, W | 1 |
| Birnbaum, SG | 1 |
| Hu, JH | 1 |
| Worley, PF | 1 |
| Gibson, JR | 1 |
| Huber, KM | 1 |
| Siomi, MC | 1 |
| Higashijima, K | 1 |
| Ishizuka, A | 1 |
| Siomi, H | 1 |
8 other studies available for serine and Fragile X Syndrome
| Article | Year |
|---|---|
Deficits in Prenatal Serine Biosynthesis Underlie the Mitochondrial Dysfunction Associated with the Autism-Linked
Topics: 5' Untranslated Regions; Adult; Amniocentesis; Amniotic Fluid; Autistic Disorder; Citric Acid Cycle; | 2021 |
Rescue of NMDAR-dependent synaptic plasticity in Fmr1 knock-out mice.
Topics: Animals; Fragile X Mental Retardation Protein; Fragile X Syndrome; Glycine; Hippocampus; Long-Term P | 2015 |
Deficits in the activity of presynaptic γ-aminobutyric acid type B receptors contribute to altered neuronal excitability in fragile X syndrome.
Topics: Aged; Aged, 80 and over; Animals; Behavior, Animal; Disease Models, Animal; Fragile X Mental Retarda | 2017 |
Dysregulation of mTOR signaling in fragile X syndrome.
Topics: Adaptor Proteins, Signal Transducing; Animals; CA1 Region, Hippocampal; Carrier Proteins; Cell Cycle | 2010 |
Evidence of reactive astrocytes but not peripheral immune system activation in a mouse model of Fragile X syndrome.
Topics: Animals; Astrocytes; Brain; Cytokines; Disease Models, Animal; Female; Fragile X Mental Retardation | 2010 |
In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation.
Topics: Animals; Animals, Genetically Modified; Brain; Cytoskeleton; Disease Models, Animal; Drosophila mela | 2012 |
Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
Topics: Analysis of Variance; Animals; Carrier Proteins; Cycloheximide; Disease Models, Animal; Electric Sti | 2012 |
Casein kinase II phosphorylates the fragile X mental retardation protein and modulates its biological properties.
Topics: Amino Acid Sequence; Animals; Casein Kinase II; Cell Fractionation; Cell Line; DNA-Binding Proteins; | 2002 |