8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with Fragile X Syndrome in 1 studies
8-Hydroxy-2-(di-n-propylamino)tetralin: A serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.
8-OH-DPAT : A tetralin substituted at positions 1 and 7 by hydroxy and dipropylamino groups respectively
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Costa, L | 1 |
| Spatuzza, M | 1 |
| D'Antoni, S | 1 |
| Bonaccorso, CM | 1 |
| Trovato, C | 1 |
| Musumeci, SA | 1 |
| Leopoldo, M | 1 |
| Lacivita, E | 1 |
| Catania, MV | 1 |
| Ciranna, L | 1 |
1 other study available for 8-hydroxy-2-(di-n-propylamino)tetralin and Fragile X Syndrome
| Article | Year |
|---|---|
Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and Fmr1 knockout mice, a model of Fragile X syndrome.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Disease Models, Animal; Excitatory Postsynaptic Pot | 2012 |