caffeine has been researched along with Fragile X Syndrome in 3 studies
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chromosome analyses of lymphocytes cultured in a medium supplemented with caffeine showed a significantly higher frequency of fragile X(p22) in 13 girls with the Rett syndrome (RS) than in 9 healthy controls (p less than 0." | 7.68 | The Rett syndrome related to fragile X(P22) in caffeine-induced lymphocyte culture. ( Anvret, M; Mellquist, L; Oden, A; Wahlström, J; Witt-Engerström, I, 1990) |
| "Chromosome analyses of lymphocytes cultured in a medium supplemented with caffeine showed a significantly higher frequency of fragile X(p22) in 13 girls with the Rett syndrome (RS) than in 9 healthy controls (p less than 0." | 3.68 | The Rett syndrome related to fragile X(P22) in caffeine-induced lymphocyte culture. ( Anvret, M; Mellquist, L; Oden, A; Wahlström, J; Witt-Engerström, I, 1990) |
| "Caffeine did not enhance the expression of the fra(X) in the PBLC or in the three LCL from fra(X) expressing individuals nor did it elicit fra(X) expression in LCL from a non-expressing obligate-carrier female and a transmitting male." | 1.27 | The effect of caffeine on fragile X expression. ( Abruzzo, MA; Jacobs, PA; Mayer, M; Pettay, D, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wahlström, J | 1 |
| Witt-Engerström, I | 1 |
| Mellquist, L | 1 |
| Anvret, M | 1 |
| Oden, A | 1 |
| Abruzzo, MA | 1 |
| Pettay, D | 1 |
| Mayer, M | 1 |
| Jacobs, PA | 1 |
| Nussbaum, RL | 1 |
| Ledbetter, DH | 1 |
1 review available for caffeine and Fragile X Syndrome
| Article | Year |
|---|---|
Fragile X syndrome: a unique mutation in man.
Topics: Caffeine; Chromosome Fragility; Female; Fragile X Syndrome; Genetic Counseling; Genetic Linkage; Gen | 1986 |
2 other studies available for caffeine and Fragile X Syndrome
| Article | Year |
|---|---|
The Rett syndrome related to fragile X(P22) in caffeine-induced lymphocyte culture.
Topics: Adolescent; Adult; Caffeine; Cell Division; Cells, Cultured; Child; Child, Preschool; Female; Fragil | 1990 |
The effect of caffeine on fragile X expression.
Topics: Caffeine; Cells, Cultured; Chromosome Aberrations; Chromosome Fragile Sites; Chromosome Fragility; F | 1986 |