thymidine has been researched along with Fragile X Syndrome in 15 studies
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Folate metabolism and the effects of folic acid on chromosome stability were studied in four related patients with the fragile X syndrome." | 3.67 | Folate metabolism and chromosomal stability in the fragile X syndrome. ( Arthur, DC; Branda, RF; Danzl, TJ; King, RA; Woods, WG, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (46.67) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gardiner, GB | 1 |
| Wenger, SL | 1 |
| Steele, MW | 1 |
| Branda, RF | 1 |
| Arthur, DC | 1 |
| Woods, WG | 1 |
| Danzl, TJ | 1 |
| King, RA | 1 |
| Jenkins, EC | 2 |
| Morys, I | 1 |
| Henderson, J | 1 |
| Genovese, M | 1 |
| Carter, M | 1 |
| Li, SY | 1 |
| Houck, GE | 1 |
| Ding, X | 1 |
| Stark-Houck, SL | 1 |
| Dobkin, CS | 1 |
| Dewald, GW | 1 |
| Buckley, DD | 1 |
| Spurbeck, JL | 1 |
| Jalal, SM | 1 |
| Griffiths, MJ | 1 |
| Strachan, MC | 1 |
| Krawczun, MS | 1 |
| Brooks, SE | 1 |
| Brooks, SL | 1 |
| Sherman, SL | 1 |
| Brown, WT | 2 |
| Zaslav, AL | 1 |
| Kähkönen, M | 1 |
| Haataja, R | 1 |
| Leisti, J | 1 |
| Webb, T | 1 |
| Jacobs, PA | 1 |
| Kuwano, A | 1 |
| Murano, I | 1 |
| Kajii, T | 1 |
| Sutherland, GR | 2 |
| Baker, E | 2 |
| Purvis-Smith, S | 1 |
| Hockey, A | 1 |
| Krumins, E | 1 |
| Eichenbaum, SZ | 1 |
| Hori, T | 2 |
| Takahashi, E | 1 |
| Tsuji, H | 1 |
| Tsuji, S | 1 |
| Murata, M | 1 |
| Nussbaum, RL | 1 |
| Ledbetter, DH | 1 |
| Fratini, A | 1 |
2 reviews available for thymidine and Fragile X Syndrome
| Article | Year |
|---|---|
Cytogenetic guidelines for fragile X studies tested in routine practice.
Topics: Adolescent; Adult; Cell Count; Cells, Cultured; Child; Child, Preschool; Chromosome Aberrations; Cul | 1992 |
Fragile X syndrome: a unique mutation in man.
Topics: Caffeine; Chromosome Fragility; Female; Fragile X Syndrome; Genetic Counseling; Genetic Linkage; Gen | 1986 |
13 other studies available for thymidine and Fragile X Syndrome
| Article | Year |
|---|---|
In vitro reversal of fragile-X expression by exogenous thymidine.
Topics: Culture Media; Floxuridine; Fragile X Syndrome; Humans; In Vitro Techniques; Lymphocytes; Male; Sex | 1984 |
Folate metabolism and chromosomal stability in the fragile X syndrome.
Topics: Adult; Bone Marrow; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; DNA; Erythrocyt | 1984 |
Fragile X induction systems in CVS cultures: effect on cytogenetic, PCR, and genomic Southern Blot DNA analyses of the FMR-1 gene.
Topics: Blotting, Southern; Cells, Cultured; Chorionic Villi; Chorionic Villi Sampling; Chromosome Banding; | 1994 |
A single lymphocyte culture for fragile X induction and prometaphase chromosome analysis.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Chromosome Fragility; Deoxycytidine; Fe | 1991 |
Laboratory aspects of prenatal fra(X) detection.
Topics: Amniocentesis; Cells, Cultured; Chorionic Villi Sampling; Dose-Response Relationship, Drug; False Ne | 1991 |
Simultaneous expression of the rare and common fragile sites on the X chromosome.
Topics: Aphidicolin; Chromosome Aberrations; Chromosome Banding; Ethanol; Female; Floxuridine; Fragile X Syn | 1991 |
Uridine enhances expression of the fragile X chromosome in human lymphocytes.
Topics: Culture Media; Folic Acid; Fragile X Syndrome; Humans; Lymphocytes; Mitosis; Thymidine; Uridine | 1991 |
Fragile Xq27.3 in female heterozygotes for the Martin-Bell syndrome.
Topics: Bromodeoxyuridine; Chromosome Fragility; Dosage Compensation, Genetic; Female; Fragile X Syndrome; G | 1990 |
Cell type-dependent difference in the distribution and frequency of excess thymidine-induced common fragile sites: T lymphocytes and skin fibroblasts.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Chromosome Fragile Sites; Chromosome Fr | 1990 |
Prenatal diagnosis of the fragile X using thymidine induction.
Topics: Adult; Amniocentesis; Australia; Chorionic Villi; Female; Floxuridine; Fragile X Syndrome; Humans; M | 1987 |
Fragile X expression in thymidine-prototrophic and auxotrophic human-mouse somatic cell hybrids under low and high thymidylate stress conditions.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; Deoxycytosine Nucleotides; Fragile X Syndrome; Gene Expressi | 1988 |
[Fragile sites on human chromosomes and cancer-specific chromosomal rearrangements].
Topics: Animals; Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; Fragile X Syndrome; Hum | 1986 |
Excess thymidine induces folate sensitive fragile sites.
Topics: Base Sequence; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; DNA; Female; Folic A | 1985 |