diazepam has been researched along with Fragile X Syndrome in 3 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jaeschke, G | 1 |
| Kolczewski, S | 1 |
| Spooren, W | 1 |
| Vieira, E | 1 |
| Bitter-Stoll, N | 1 |
| Boissin, P | 1 |
| Borroni, E | 1 |
| Büttelmann, B | 1 |
| Ceccarelli, S | 1 |
| Clemann, N | 1 |
| David, B | 1 |
| Funk, C | 1 |
| Guba, W | 1 |
| Harrison, A | 1 |
| Hartung, T | 1 |
| Honer, M | 1 |
| Huwyler, J | 1 |
| Kuratli, M | 1 |
| Niederhauser, U | 1 |
| Pähler, A | 1 |
| Peters, JU | 1 |
| Petersen, A | 1 |
| Prinssen, E | 1 |
| Ricci, A | 1 |
| Rueher, D | 1 |
| Rueher, M | 1 |
| Schneider, M | 1 |
| Spurr, P | 1 |
| Stoll, T | 1 |
| Tännler, D | 1 |
| Wichmann, J | 1 |
| Porter, RH | 1 |
| Wettstein, JG | 1 |
| Lindemann, L | 1 |
| Carreno-Munoz, MI | 1 |
| Martins, F | 1 |
| Medrano, MC | 1 |
| Aloisi, E | 1 |
| Pietropaolo, S | 1 |
| Dechaud, C | 1 |
| Subashi, E | 1 |
| Bony, G | 1 |
| Ginger, M | 1 |
| Moujahid, A | 1 |
| Frick, A | 1 |
| Leinekugel, X | 1 |
| Heulens, I | 1 |
| D'Hulst, C | 1 |
| Van Dam, D | 1 |
| De Deyn, PP | 1 |
| Kooy, RF | 1 |
3 other studies available for diazepam and Fragile X Syndrome
| Article | Year |
|---|---|
Metabotropic glutamate receptor 5 negative allosteric modulators: discovery of 2-chloro-4-[1-(4-fluorophenyl)-2,5-dimethyl-1H-imidazol-4-ylethynyl]pyridine (basimglurant, RO4917523), a promising novel medicine for psychiatric diseases.
Topics: Allosteric Regulation; Animals; Depression; Dose-Response Relationship, Drug; Drug Discovery; Fragil | 2015 |
Potential Involvement of Impaired BK
Topics: Animals; Anti-Anxiety Agents; Diazepam; Disease Models, Animal; Environment; Fragile X Mental Retard | 2018 |
Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model.
Topics: Analysis of Variance; Anesthetics; Animals; Diazepam; Disease Models, Animal; Dose-Response Relation | 2012 |