pyrimethamine has been researched along with Fragile X Syndrome in 1 studies
Maloprim: contains above 2 cpds
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, JC | 1 |
| Beardsley, GP | 1 |
| Erbe, RW | 1 |
1 other study available for pyrimethamine and Fragile X Syndrome
| Article | Year |
|---|---|
Antifolate-induced misincorporation of deoxyuridine monophosphate into DNA by cells from patients with the fragile X syndrome.
Topics: Cells, Cultured; Deoxyuracil Nucleotides; DNA; DNA Glycosylases; Floxuridine; Folic Acid Antagonists | 1985 |