methadone has been researched along with Fragile X Syndrome in 1 studies
Methadone: A synthetic opioid that is used as the hydrochloride. It is an opioid analgesic that is primarily a mu-opioid agonist. It has actions and uses similar to those of MORPHINE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1082-3)
methadone : A racemate comprising equimolar amounts of dextromethadone and levomethadone. It is a opioid analgesic which is used as a painkiller and as a substitute for heroin in the treatment of heroin addiction.
6-(dimethylamino)-4,4-diphenylheptan-3-one : A ketone that is heptan-3-one substituted by a dimethylamino group at position 6 and two phenyl groups at position 4.
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The fragile X-associated tremor ataxia syndrome (FXTAS) is caused by the premutation in FMR1 gene." | 1.42 | Methadone use in a male with the FMRI premutation and FXTAS. ( Adams, PE; Faradz, SM; Hagerman, RJ; Lozano, R; Muzar, Z; Schneider, A; Tassone, F, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muzar, Z | 1 |
| Lozano, R | 1 |
| Schneider, A | 1 |
| Adams, PE | 1 |
| Faradz, SM | 1 |
| Tassone, F | 1 |
| Hagerman, RJ | 1 |
1 other study available for methadone and Fragile X Syndrome
| Article | Year |
|---|---|
Methadone use in a male with the FMRI premutation and FXTAS.
Topics: Ataxia; Disease Progression; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expressi | 2015 |