betaine has been researched along with Fragile X Syndrome in 3 studies
glycine betaine : The amino acid betaine derived from glycine.
Fragile X Syndrome: A condition characterized genotypically by mutation of the distal end of the long arm of the X chromosome (at gene loci FRAXA or FRAXE) and phenotypically by cognitive impairment, hyperactivity, SEIZURES, language delay, and enlargement of the ears, head, and testes. INTELLECTUAL DISABILITY occurs in nearly all males and roughly 50% of females with the full mutation of FRAXA. (From Menkes, Textbook of Child Neurology, 5th ed, p226)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report on a unified rapid betaine-based-PCR protocol for amplification of the (CAG)n region in Huntington disease (HD) and the (CGG)n region in Fragile X syndrome (FXS), followed by an electrophoretic separation on automated sequencer for precise determination of the triplet numbers." | 3.76 | A unified rapid PCR method for detection of normal and expanded trinucleotide alleles of CAG repeats in huntington chorea and CGG repeats in fragile X syndrome. ( Georgieva, B; Mitev, V; Todorov, T; Todorova, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meguid, NA | 1 |
| Ismail, MF | 1 |
| El-Mahdy, RS | 1 |
| Barakat, MA | 1 |
| El-Awady, MK | 1 |
| Todorov, T | 1 |
| Todorova, A | 1 |
| Georgieva, B | 1 |
| Mitev, V | 1 |
| Baskaran, N | 1 |
| Kandpal, RP | 1 |
| Bhargava, AK | 1 |
| Glynn, MW | 1 |
| Bale, A | 1 |
| Weissman, SM | 1 |
3 other studies available for betaine and Fragile X Syndrome
| Article | Year |
|---|---|
Simple molecular diagnostic method for fragile X syndrome in Egyptian patients: pilot study.
Topics: Adult; Alleles; Betaine; Case-Control Studies; Child; Consanguinity; Early Diagnosis; Egypt; Female; | 2014 |
A unified rapid PCR method for detection of normal and expanded trinucleotide alleles of CAG repeats in huntington chorea and CGG repeats in fragile X syndrome.
Topics: Alleles; Betaine; Fragile X Syndrome; Humans; Huntington Disease; Male; Polymerase Chain Reaction; R | 2010 |
Uniform amplification of a mixture of deoxyribonucleic acids with varying GC content.
Topics: Base Composition; Betaine; Carrier Proteins; Dimethyl Sulfoxide; DNA; DNA-Directed DNA Polymerase; F | 1996 |