| Assay ID | Title | Year | Journal | Article |
|---|
| AID238946 | Inhibition of [3H]spiperone binding to human Dopamine D2L receptor expressed in Sf9 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID64662 | Binding affinity for human Dopamine receptor D2 (short) by [3H]- spiperone displacement. | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID415738 | Selectivity for dopamine D3 receptor over dopamine D2 receptor | 2009 | Bioorganic & medicinal chemistry letters, Mar-15, Volume: 19, Issue:6
| Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands. |
| AID277674 | Displacement of [3H]spiperone from human dopamine D4.4 expressed in CHO cell membrane | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID254381 | Binding affinity towards Dopamine D2S receptor using CHO cell line and [3H]spiperone as radioligand | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID255166 | Ratio of selectivity towards Dopamine receptor D4.4 to that of Dopamine D3 receptor | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID415504 | Antagonist activity at human D3 receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesis | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. |
| AID243003 | Ratio of binding affinity at dopamine D2L over D3 receptors | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID415493 | Displacement of [125]IABN from human cloned D2 like receptor expressed in HEK293 cells | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. |
| AID415509 | Displacement of [3H]8-OH-DPAT from 5HT1A receptor | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. |
| AID239207 | Binding affinity towards adrenergic alpha-1 receptor from porcine cortical membranes using [3H]-prazosin | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. |
| AID229809 | Relative binding to Dopamine D2 long and D3 receptors (Ratio of Ki) | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands. |
| AID64805 | Rate of [3H]-thymidine uptake compared to quinpirole (100%) in Dopamine receptor D3 expressing CHO cells; No effect | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID238970 | Inhibition of [3H]YM-09151-2 binding to human Dopamine D2L receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID277668 | Selectivity for dopamine D3 over dopamine D2 | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID255164 | Ratio of selectivity towards Dopamine receptor D2L to that of Dopamine receptor D3 | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID238643 | Binding affinity for human dopamine D3 receptor | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID254379 | Binding affinity towards Dopamine receptor D3 using CHO cell line and [3H]-spiperone as radioligand | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID415503 | Antagonist activity at human D2 like receptor expressed in HEK293 cells assessed as inhibition of quinpirole-stimulated mitogenesis | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. |
| AID249434 | Relative inhibition of quinpirole stimulation at human dopamine D2 and D3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID238881 | Binding affinity towards human D3 receptor using [3H]spiperone expressed in CHO cells | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. |
| AID255165 | Ratio of selectivity towards Dopamine receptor D2S to that of Dopamine receptor D3 | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID239030 | Binding affinity towards 5-HT1A receptor from porcine cortical membranes using [3H]8-OH-DPAT | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. |
| AID238274 | Binding affinity for Dopamine receptor D4 | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Modeling the similarity and divergence of dopamine D2-like receptors and identification of validated ligand-receptor complexes. |
| AID239031 | Binding affinity towards 5-HT2 receptor from porcine cortical membranes using [3H]ketanserin | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. |
| AID242943 | Ratio of dopamine receptor D3 and D4 ki values | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Modeling the similarity and divergence of dopamine D2-like receptors and identification of validated ligand-receptor complexes. |
| AID238963 | Binding affinity towards human D2 long receptor using [3H]spiperone expressed in CHO cells | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. |
| AID594051 | Binding affinity to dopamine D3 receptor | 2011 | Bioorganic & medicinal chemistry letters, May-01, Volume: 21, Issue:9
| Aromatic ring functionalization of benzolactam derivatives: new potent dopamine D3 receptor ligands. |
| AID749539 | Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma counting analysis | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands. |
| AID254417 | Binding affinity towards Dopamine receptor D1 using porcine striatal membrane and [3H]-SCH- 23390 as radioligand | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID238994 | Binding affinity towards human D2 short receptor using [3H]spiperone expressed in CHO cells | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. |
| AID248806 | Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D3 receptor | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID415495 | Displacement of [125]IABN from human D4 receptor expressed in HEK293 cells | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. |
| AID63360 | Binding affinity for porcine Dopamine receptor D1 by [3H]-SCH- 23390 displacement. | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID238920 | Inhibition of [3H]spiperone binding to human Dopamine D4 receptor expressed in Sf9 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID243111 | Relative binding affinity for human dopamine D2 and D3 receptors | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID749537 | Selectivity ratio of Ki for human dopamine D2L receptor to Ki for human dopamine D3 receptor | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands. |
| AID36141 | Displacement of [3H]- ketanserin from porcine Alpha-1 adrenergic receptor | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID238699 | Binding affinity for human dopamine receptor D2 long | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Modeling the similarity and divergence of dopamine D2-like receptors and identification of validated ligand-receptor complexes. |
| AID254385 | Binding affinity towards Dopamine receptor D 4.4 using CHO cell line and [3H]spiperone as radioligand | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID415497 | Selectivity of Ki for human D4 receptor to Ki for human D3 receptor | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. |
| AID238945 | Inhibition of [3H]spiperone binding to human Dopamine D2L receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID415494 | Displacement of [125]IABN from human D3 receptor expressed in HEK293 cells | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. |
| AID246572 | Inhibition of quinpirole stimulation of mitogenesis at human dopamine D2 receptors expressed in Chinese hamster ovary cells | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID234365 | Selectivity for human D4 compared to D3. | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID749540 | Displacement of [125I]ABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma counting analysis | 2013 | Bioorganic & medicinal chemistry, Jun-01, Volume: 21, Issue:11
| Evaluation of N-phenyl homopiperazine analogs as potential dopamine D3 receptor selective ligands. |
| AID238613 | Binding affinity for human dopamine receptor D3 | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Modeling the similarity and divergence of dopamine D2-like receptors and identification of validated ligand-receptor complexes. |
| AID3974 | Displacement of [3H]- 8-OH-DPAT from porcine 5-hydroxytryptamine 1A receptor | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID254390 | Binding affinity towards 5-HT1A receptor using porcine cortical membrane and [3H]-8-OH-DPAT as radioligand | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID594019 | Selectivity ratio of Ki for dopamine D2 long receptor to Ki for dopamine D3 receptor | 2011 | Bioorganic & medicinal chemistry letters, May-01, Volume: 21, Issue:9
| Aromatic ring functionalization of benzolactam derivatives: new potent dopamine D3 receptor ligands. |
| AID277677 | Binding affinity to dopamine D2 | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID238919 | Inhibition of [3H]spiperone binding to human Dopamine D4 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID65085 | Binding affinity at dopamine receptor D2 on Sf9 cells by [125I]IABN displacement. | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands. |
| AID249398 | Dopamine receptor D2/D3 selectivity ratio from in vitro functional assays | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID253842 | Calculated partition coefficient (clogP) (Pomona) | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID238935 | Binding affinity towards D1 receptor from porcine striatal membranes using [3H]-SCH- 23390 | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. |
| AID238642 | Binding affinity for human dopamine D2 receptor | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID1245094 | Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK293 cell membranes by radioligand competition binding assay | 2015 | Bioorganic & medicinal chemistry, Sep-15, Volume: 23, Issue:18
| 1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation. |
| AID64982 | Binding affinity for human Dopamine receptor D3 by [3H]- spiperone displacement. | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID415496 | Selectivity of Ki for human D2 like receptor to Ki for human D3 receptor | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. |
| AID1245089 | Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cell membranes by radioligand competition binding assay | 2015 | Bioorganic & medicinal chemistry, Sep-15, Volume: 23, Issue:18
| 1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation. |
| AID64335 | Binding affinity for human Dopamine receptor D2 (long) by [3H]- spiperone displacement. | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID242944 | Ratio of dopamine receptor D2 long and D3 ki values | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Modeling the similarity and divergence of dopamine D2-like receptors and identification of validated ligand-receptor complexes. |
| AID238887 | Inhibition of [3H]spiperone binding to rat Dopamine D3 receptor expressed in Sf9 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID234363 | Selectivity for human D2 (long) compared to D3. | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID254427 | Binding affinity towards Alpha-1 adrenergic receptor using porcine cortical membrane and [3H]prazosin as radioligand | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID254380 | Binding affinity towards Dopamine D2L receptor using CHO cell line and [3H]spiperone as radioligand | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID238918 | Inhibition of [3H]spiperone binding to human Dopamine D3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID234364 | Selectivity for human D2 (short) compared to D3. | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID242945 | Ratio of dopamine receptor D2 long and D4 ki values | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Modeling the similarity and divergence of dopamine D2-like receptors and identification of validated ligand-receptor complexes. |
| AID63521 | Binding affinity for human Dopamine receptor D4 by [3H]- spiperone displacement. | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID246573 | Inhibition of quinpirole stimulation of mitogenesis at human dopamine D3 receptors expressed in Chinese hamster ovary cells | 2005 | Journal of medicinal chemistry, Feb-10, Volume: 48, Issue:3
| Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor. |
| AID238948 | Inhibition of [125I]IABN binding to human Dopamine D3 receptor expressed in HEK 293 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID277669 | Selectivity for dopamine D3 over dopamine D4 | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID254393 | Binding affinity towards 5-HT2 receptor using porcine cortical membrane and [3H]ketanserin as radioligand | 2005 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 15, Issue:21
| Synthesis and evaluation of 18F-labeled dopamine D3 receptor ligands as potential PET imaging agents. |
| AID238914 | Binding affinity towards human D4.4 receptor using [3H]spiperone expressed in CHO cells | 2004 | Bioorganic & medicinal chemistry letters, Aug-02, Volume: 14, Issue:15
| Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype. |
| AID65603 | Binding affinity at dopamine receptor D3 on Sf9 cells by [125I]IABN displacement. | 2004 | Bioorganic & medicinal chemistry letters, Jan-05, Volume: 14, Issue:1
| Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands. |
| AID415508 | Displacement of [3H]SCH23390 from D1 receptor | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N-(4-(4-(2,3-dichloro- or 2-methoxyphenyl)piperazin-1-yl)butyl)heterobiarylcarboxamides with functionalized linking chains as high affinity and enantioselective D3 receptor antagonists. |
| AID238971 | Inhibition of [125I]IABN binding to human Dopamine D2L receptor expressed in HEK 293 cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID238947 | Inhibition of [3H]YM-09151-2 binding to human Dopamine D3 receptor expressed in CHO cells | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID248805 | Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D2 receptor | 2005 | Journal of medicinal chemistry, Jun-02, Volume: 48, Issue:11
| Dopamine D3 receptor partial agonists and antagonists as potential drug abuse therapeutic agents. |
| AID5028 | Binding affinity for porcine 5-hydroxytryptamine 2 receptor using [3H]- ketanserin | 2002 | Journal of medicinal chemistry, Oct-10, Volume: 45, Issue:21
| Interactive SAR studies: rational discovery of super-potent and highly selective dopamine D3 receptor antagonists and partial agonists. |
| AID277673 | Displacement of [3H]spiperone from human dopamine D3 expressed in CHO cell membrane | 2007 | Journal of medicinal chemistry, Feb-08, Volume: 50, Issue:3
| Structure-selectivity investigations of D2-like receptor ligands by CoMFA and CoMSIA guiding the discovery of D3 selective PET radioligands. |
| AID1245087 | Selectivity index, ratio of Ki for human 5HT2A receptor to Ki for human dopamine D2 receptor | 2015 | Bioorganic & medicinal chemistry, Sep-15, Volume: 23, Issue:18
| 1,4-Disubstituted aromatic piperazines with high 5-HT2A/D2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |