a 419259 profile

ID Source	ID
PubMed CID	6539952
CHEMBL ID	45177
CHEMBL ID	47203
CHEMBL ID	1997617
SCHEMBL ID	14183078
SCHEMBL ID	16752413
SCHEMBL ID	16752462
SCHEMBL ID	14106768
SCHEMBL ID	19546827
MeSH ID	M0443732

Synonym
pyrrolo[2,3-d]pyrimidine 1
bdbm8793
chembl45177 ,
7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine
a419259 ,
a 419259
a-419259
CHEMBL47203 ,
(r)-7-[4-(4-methyl-piperazin-1-yl)-cyclohexyl]-5-(4-phenoxy-phenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-ylamine
bdbm50114585
KINOME_2527
7-[4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)pyrrolo[2,3-d]pyrimidin-4-amine
7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine
7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine
vse ,
HY-15764
CS-1704
SCHEMBL14183078
SCHEMBL16752413
SCHEMBL16752462
CHEMBL1997617
364042-47-7
SCHEMBL14106768
AKOS030526794
7-[trans-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine
FDVSOQRNTAPCHB-YHBQERECSA-N
NCGC00370980-02
rk2044 hck inhibitor
SCHEMBL19546827
bdbm243041
BCP25094
Q27467116
Q27467117
GS-9009
rk20449 hck inhibitor (cis)
rk 20449
rk 20448
A14323
rk20448-trihydrochloride
479501-40-1
rk-20448
AKOS037653309
5-(4-phenoxyphenyl)-7-[(1s,4s)-4-(4-methylpiperazin-1-yl)cyclohexyl]-7h-pyrrolo[2,3-d]pyrimidin-4-amine
rk20448

Excerpt	Reference	Relevance
" The para-phenoxyphenyl analogue 2 is an orally active lck inhibitor with a bioavailability of 69% and exhibits an extended duration of action in animal models of T cell inhibition."	( Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck -- a selectivity insight. Burchat, AF; Calderwood, DJ; Friedman, MM; Hirst, GC; Li, B; Rafferty, P; Ritter, K; Skinner, BS, 2002)	0.31
"The ATP-binding cassette transporter P-glycoprotein (P-gp) is known to limit both brain penetration and oral bioavailability of many chemotherapy drugs."	( A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Ambudkar, SV; Brimacombe, KR; Chen, L; Gottesman, MM; Guha, R; Hall, MD; Klumpp-Thomas, C; Lee, OW; Lee, TD; Lusvarghi, S; Robey, RW; Shen, M; Tebase, BG, 2019)	0.51

Protein Targets (32)

Potency Measurements

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
PPM1D protein	Homo sapiens (human)	Potency	11.7086	0.0052	9.4661	32.9993	AID1347411
cytochrome P450 family 3 subfamily A polypeptide 4	Homo sapiens (human)	Potency	0.6008	0.0123	7.9835	43.2770	AID1645841
cytochrome P450 2D6	Homo sapiens (human)	Potency	11.9877	0.0010	8.3798	61.1304	AID1645840
Interferon beta	Homo sapiens (human)	Potency	11.7086	0.0033	9.1582	39.8107	AID1347411
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Inhibition Measurements

Protein	Taxonomy	Measurement	Average	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Serine/threonine-protein kinase D3	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	1.1701	10.0000	AID164946
Protein kinase C gamma type	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	1.0354	10.0000	AID164946
Protein kinase C beta type	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	0.5542	10.0000	AID164946
Insulin receptor	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0017	0.8479	10.0000	AID91678
Tyrosine-protein kinase Lck	Homo sapiens (human)	IC50 (µMol)	0.2228	0.0002	1.3173	10.0000	AID1796232; AID223955; AID223984; AID748778
Tyrosine-protein kinase Fyn	Homo sapiens (human)	IC50 (µMol)	0.5224	0.0002	1.6789	8.6800	AID1407822; AID1803322; AID223948
Cyclin-dependent kinase 1	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0004	1.3452	10.0000	AID51721
Tyrosine-protein kinase Lyn	Homo sapiens (human)	IC50 (µMol)	0.1531	0.0002	0.5594	5.2000	AID1803322; AID224282
Hepatocyte growth factor receptor	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0004	0.3722	10.0000	AID220178
Tyrosine-protein kinase HCK	Homo sapiens (human)	IC50 (µMol)	0.0004	0.0001	1.2226	7.7000	AID1366202; AID1487298; AID1487299
Platelet-derived growth factor receptor beta	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0006	0.8007	8.5000	AID161092
Cytochrome P450 2D6	Homo sapiens (human)	IC50 (µMol)	0.0004	0.0000	2.0151	10.0000	AID1366202
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50 (µMol)	0.3464	0.0002	0.5335	10.0000	AID1796232; AID1803322; AID205329; AID205333
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	0.4912	10.0000	AID161092
Protein kinase C alpha type	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	0.9720	10.0000	AID164946
Protein kinase C eta type	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	0.7971	10.0000	AID164946
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	IC50 (µMol)	2.0881	0.0000	0.4830	8.8000	AID1796232; AID216640; AID216770
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	IC50 (µMol)	0.0240	0.0001	0.3275	9.5480	AID1366201
Tyrosine-protein kinase CSK	Homo sapiens (human)	IC50 (µMol)	2.1555	0.0013	1.3352	5.1800	AID213575; AID55200
Protein kinase C iota type	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	2.0378	10.0000	AID164946
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0011	1.2309	9.7000	AID220423
Tyrosine-protein kinase Blk	Homo sapiens (human)	IC50 (µMol)	0.2080	0.0001	0.4357	5.4700	AID38030
Protein kinase C epsilon type	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	0.8029	10.0000	AID164946
Angiopoietin-1 receptor	Homo sapiens (human)	IC50 (µMol)	1.0121	0.0004	0.5553	9.0700	AID1796232; AID209358; AID209359; AID209361; AID748776
Protein kinase C theta type	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	0.9897	10.0000	AID164946
Protein kinase C zeta type	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	2.4453	10.0000	AID164946
Protein kinase C delta type	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	0.8448	10.0000	AID164946
Serine/threonine-protein kinase D1	Homo sapiens (human)	IC50 (µMol)	20.0000	0.0001	1.2319	10.0000	AID164946
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Biological Processes (686)

Process	via Protein(s)	Taxonomy
protein phosphorylation	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein kinase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D3	Homo sapiens (human)
sphingolipid biosynthetic process	Serine/threonine-protein kinase D3	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase D3	Homo sapiens (human)
phospholipase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D3	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell activation involved in immune response	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway	Interferon beta	Homo sapiens (human)
cell surface receptor signaling pathway via JAK-STAT	Interferon beta	Homo sapiens (human)
response to virus	Interferon beta	Homo sapiens (human)
positive regulation of autophagy	Interferon beta	Homo sapiens (human)
cytokine-mediated signaling pathway	Interferon beta	Homo sapiens (human)
natural killer cell activation	Interferon beta	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation of STAT protein	Interferon beta	Homo sapiens (human)
cellular response to interferon-beta	Interferon beta	Homo sapiens (human)
B cell proliferation	Interferon beta	Homo sapiens (human)
negative regulation of viral genome replication	Interferon beta	Homo sapiens (human)
innate immune response	Interferon beta	Homo sapiens (human)
positive regulation of innate immune response	Interferon beta	Homo sapiens (human)
regulation of MHC class I biosynthetic process	Interferon beta	Homo sapiens (human)
negative regulation of T cell differentiation	Interferon beta	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Interferon beta	Homo sapiens (human)
defense response to virus	Interferon beta	Homo sapiens (human)
type I interferon-mediated signaling pathway	Interferon beta	Homo sapiens (human)
neuron cellular homeostasis	Interferon beta	Homo sapiens (human)
cellular response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
cellular response to virus	Interferon beta	Homo sapiens (human)
negative regulation of Lewy body formation	Interferon beta	Homo sapiens (human)
negative regulation of T-helper 2 cell cytokine production	Interferon beta	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Interferon beta	Homo sapiens (human)
response to exogenous dsRNA	Interferon beta	Homo sapiens (human)
B cell differentiation	Interferon beta	Homo sapiens (human)
natural killer cell activation involved in immune response	Interferon beta	Homo sapiens (human)
adaptive immune response	Interferon beta	Homo sapiens (human)
T cell activation involved in immune response	Interferon beta	Homo sapiens (human)
humoral immune response	Interferon beta	Homo sapiens (human)
protein phosphorylation	Protein kinase C gamma type	Homo sapiens (human)
chemical synaptic transmission	Protein kinase C gamma type	Homo sapiens (human)
learning or memory	Protein kinase C gamma type	Homo sapiens (human)
chemosensory behavior	Protein kinase C gamma type	Homo sapiens (human)
response to toxic substance	Protein kinase C gamma type	Homo sapiens (human)
phosphorylation	Protein kinase C gamma type	Homo sapiens (human)
negative regulation of protein ubiquitination	Protein kinase C gamma type	Homo sapiens (human)
regulation of response to food	Protein kinase C gamma type	Homo sapiens (human)
positive regulation of mismatch repair	Protein kinase C gamma type	Homo sapiens (human)
negative regulation of protein catabolic process	Protein kinase C gamma type	Homo sapiens (human)
regulation of circadian rhythm	Protein kinase C gamma type	Homo sapiens (human)
response to morphine	Protein kinase C gamma type	Homo sapiens (human)
negative regulation of neuron apoptotic process	Protein kinase C gamma type	Homo sapiens (human)
response to pain	Protein kinase C gamma type	Homo sapiens (human)
rhythmic process	Protein kinase C gamma type	Homo sapiens (human)
regulation of phagocytosis	Protein kinase C gamma type	Homo sapiens (human)
long-term synaptic potentiation	Protein kinase C gamma type	Homo sapiens (human)
innervation	Protein kinase C gamma type	Homo sapiens (human)
presynaptic modulation of chemical synaptic transmission	Protein kinase C gamma type	Homo sapiens (human)
negative regulation of proteasomal protein catabolic process	Protein kinase C gamma type	Homo sapiens (human)
response to psychosocial stress	Protein kinase C gamma type	Homo sapiens (human)
regulation of synaptic vesicle exocytosis	Protein kinase C gamma type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C gamma type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C gamma type	Homo sapiens (human)
adaptive immune response	Protein kinase C beta type	Homo sapiens (human)
chromatin remodeling	Protein kinase C beta type	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Protein kinase C beta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C beta type	Homo sapiens (human)
calcium ion transport	Protein kinase C beta type	Homo sapiens (human)
intracellular calcium ion homeostasis	Protein kinase C beta type	Homo sapiens (human)
apoptotic process	Protein kinase C beta type	Homo sapiens (human)
mitotic nuclear membrane disassembly	Protein kinase C beta type	Homo sapiens (human)
signal transduction	Protein kinase C beta type	Homo sapiens (human)
phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
response to xenobiotic stimulus	Protein kinase C beta type	Homo sapiens (human)
response to glucose	Protein kinase C beta type	Homo sapiens (human)
regulation of glucose transmembrane transport	Protein kinase C beta type	Homo sapiens (human)
negative regulation of glucose transmembrane transport	Protein kinase C beta type	Homo sapiens (human)
regulation of dopamine secretion	Protein kinase C beta type	Homo sapiens (human)
dibenzo-p-dioxin metabolic process	Protein kinase C beta type	Homo sapiens (human)
positive regulation of vascular endothelial growth factor receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
positive regulation of insulin secretion	Protein kinase C beta type	Homo sapiens (human)
response to vitamin D	Protein kinase C beta type	Homo sapiens (human)
regulation of growth	Protein kinase C beta type	Homo sapiens (human)
B cell activation	Protein kinase C beta type	Homo sapiens (human)
positive regulation of odontogenesis of dentin-containing tooth	Protein kinase C beta type	Homo sapiens (human)
lipoprotein transport	Protein kinase C beta type	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Protein kinase C beta type	Homo sapiens (human)
post-translational protein modification	Protein kinase C beta type	Homo sapiens (human)
response to ethanol	Protein kinase C beta type	Homo sapiens (human)
positive regulation of angiogenesis	Protein kinase C beta type	Homo sapiens (human)
positive regulation of DNA-templated transcription	Protein kinase C beta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
B cell receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
positive regulation of B cell receptor signaling pathway	Protein kinase C beta type	Homo sapiens (human)
cellular response to carbohydrate stimulus	Protein kinase C beta type	Homo sapiens (human)
presynaptic modulation of chemical synaptic transmission	Protein kinase C beta type	Homo sapiens (human)
regulation of synaptic vesicle exocytosis	Protein kinase C beta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C beta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C beta type	Homo sapiens (human)
positive regulation of MAP kinase activity	Insulin receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	Insulin receptor	Homo sapiens (human)
positive regulation of receptor internalization	Insulin receptor	Homo sapiens (human)
heart morphogenesis	Insulin receptor	Homo sapiens (human)
regulation of DNA-templated transcription	Insulin receptor	Homo sapiens (human)
protein phosphorylation	Insulin receptor	Homo sapiens (human)
receptor-mediated endocytosis	Insulin receptor	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Insulin receptor	Homo sapiens (human)
learning	Insulin receptor	Homo sapiens (human)
memory	Insulin receptor	Homo sapiens (human)
positive regulation of cell population proliferation	Insulin receptor	Homo sapiens (human)
insulin receptor signaling pathway	Insulin receptor	Homo sapiens (human)
epidermis development	Insulin receptor	Homo sapiens (human)
male gonad development	Insulin receptor	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Insulin receptor	Homo sapiens (human)
male sex determination	Insulin receptor	Homo sapiens (human)
adrenal gland development	Insulin receptor	Homo sapiens (human)
positive regulation of cell migration	Insulin receptor	Homo sapiens (human)
exocrine pancreas development	Insulin receptor	Homo sapiens (human)
receptor internalization	Insulin receptor	Homo sapiens (human)
activation of protein kinase activity	Insulin receptor	Homo sapiens (human)
activation of protein kinase B activity	Insulin receptor	Homo sapiens (human)
cellular response to insulin stimulus	Insulin receptor	Homo sapiens (human)
glucose homeostasis	Insulin receptor	Homo sapiens (human)
positive regulation of protein-containing complex disassembly	Insulin receptor	Homo sapiens (human)
positive regulation of MAPK cascade	Insulin receptor	Homo sapiens (human)
positive regulation of nitric oxide biosynthetic process	Insulin receptor	Homo sapiens (human)
positive regulation of glycogen biosynthetic process	Insulin receptor	Homo sapiens (human)
positive regulation of glycolytic process	Insulin receptor	Homo sapiens (human)
positive regulation of mitotic nuclear division	Insulin receptor	Homo sapiens (human)
positive regulation of DNA-templated transcription	Insulin receptor	Homo sapiens (human)
regulation of embryonic development	Insulin receptor	Homo sapiens (human)
positive regulation of glucose import	Insulin receptor	Homo sapiens (human)
symbiont entry into host cell	Insulin receptor	Homo sapiens (human)
protein autophosphorylation	Insulin receptor	Homo sapiens (human)
positive regulation of developmental growth	Insulin receptor	Homo sapiens (human)
positive regulation of meiotic cell cycle	Insulin receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Insulin receptor	Homo sapiens (human)
positive regulation of respiratory burst	Insulin receptor	Homo sapiens (human)
cellular response to growth factor stimulus	Insulin receptor	Homo sapiens (human)
dendritic spine maintenance	Insulin receptor	Homo sapiens (human)
amyloid-beta clearance	Insulin receptor	Homo sapiens (human)
transport across blood-brain barrier	Insulin receptor	Homo sapiens (human)
neuron projection maintenance	Insulin receptor	Homo sapiens (human)
regulation of female gonad development	Insulin receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Insulin receptor	Homo sapiens (human)
multicellular organism development	Insulin receptor	Homo sapiens (human)
positive regulation of kinase activity	Insulin receptor	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Lck	Homo sapiens (human)
intracellular zinc ion homeostasis	Tyrosine-protein kinase Lck	Homo sapiens (human)
activation of cysteine-type endopeptidase activity involved in apoptotic process	Tyrosine-protein kinase Lck	Homo sapiens (human)
response to xenobiotic stimulus	Tyrosine-protein kinase Lck	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Lck	Homo sapiens (human)
hemopoiesis	Tyrosine-protein kinase Lck	Homo sapiens (human)
platelet activation	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell differentiation	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of heterotypic cell-cell adhesion	Tyrosine-protein kinase Lck	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Lck	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Tyrosine-protein kinase Lck	Homo sapiens (human)
Fc-gamma receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of T cell receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of T cell activation	Tyrosine-protein kinase Lck	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Lck	Homo sapiens (human)
release of sequestered calcium ion into cytosol	Tyrosine-protein kinase Lck	Homo sapiens (human)
regulation of lymphocyte activation	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of leukocyte cell-cell adhesion	Tyrosine-protein kinase Lck	Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Lck	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Lck	Homo sapiens (human)
response to singlet oxygen	Tyrosine-protein kinase Fyn	Homo sapiens (human)
neuron migration	Tyrosine-protein kinase Fyn	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
heart process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
calcium ion transport	Tyrosine-protein kinase Fyn	Homo sapiens (human)
G protein-coupled glutamate receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
axon guidance	Tyrosine-protein kinase Fyn	Homo sapiens (human)
learning	Tyrosine-protein kinase Fyn	Homo sapiens (human)
feeding behavior	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of cell shape	Tyrosine-protein kinase Fyn	Homo sapiens (human)
gene expression	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of gene expression	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of hydrogen peroxide biosynthetic process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein ubiquitination	Tyrosine-protein kinase Fyn	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein catabolic process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
forebrain development	Tyrosine-protein kinase Fyn	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of protein ubiquitination	Tyrosine-protein kinase Fyn	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of protein catabolic process	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase Fyn	Homo sapiens (human)
response to ethanol	Tyrosine-protein kinase Fyn	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
ephrin receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendrite morphogenesis	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
activated T cell proliferation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
modulation of chemical synaptic transmission	Tyrosine-protein kinase Fyn	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Fyn	Homo sapiens (human)
detection of mechanical stimulus involved in sensory perception of pain	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to hydrogen peroxide	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to transforming growth factor beta stimulus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of protein targeting to membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendritic spine maintenance	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of protein localization to nucleus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of glutamate receptor signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
negative regulation of dendritic spine maintenance	Tyrosine-protein kinase Fyn	Homo sapiens (human)
response to amyloid-beta	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to amyloid-beta	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to L-glutamate	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cellular response to glycine	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of protein localization to membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
regulation of calcium ion import across plasma membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
positive regulation of cysteine-type endopeptidase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Fyn	Homo sapiens (human)
G1/S transition of mitotic cell cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
microtubule cytoskeleton organization	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA replication	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA repair	Cyclin-dependent kinase 1	Homo sapiens (human)
chromatin remodeling	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Cyclin-dependent kinase 1	Homo sapiens (human)
protein phosphorylation	Cyclin-dependent kinase 1	Homo sapiens (human)
apoptotic process	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA damage response	Cyclin-dependent kinase 1	Homo sapiens (human)
mitotic nuclear membrane disassembly	Cyclin-dependent kinase 1	Homo sapiens (human)
centrosome cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
pronuclear fusion	Cyclin-dependent kinase 1	Homo sapiens (human)
response to xenobiotic stimulus	Cyclin-dependent kinase 1	Homo sapiens (human)
response to toxic substance	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of gene expression	Cyclin-dependent kinase 1	Homo sapiens (human)
negative regulation of gene expression	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of G2/M transition of mitotic cell cycle	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of Schwann cell differentiation	Cyclin-dependent kinase 1	Homo sapiens (human)
response to amine	Cyclin-dependent kinase 1	Homo sapiens (human)
response to activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cell migration	Cyclin-dependent kinase 1	Homo sapiens (human)
peptidyl-serine phosphorylation	Cyclin-dependent kinase 1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Cyclin-dependent kinase 1	Homo sapiens (human)
chromosome condensation	Cyclin-dependent kinase 1	Homo sapiens (human)
epithelial cell differentiation	Cyclin-dependent kinase 1	Homo sapiens (human)
animal organ regeneration	Cyclin-dependent kinase 1	Homo sapiens (human)
protein localization to kinetochore	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of protein import into nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of circadian rhythm	Cyclin-dependent kinase 1	Homo sapiens (human)
negative regulation of apoptotic process	Cyclin-dependent kinase 1	Homo sapiens (human)
response to ethanol	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of DNA replication	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of embryonic development	Cyclin-dependent kinase 1	Homo sapiens (human)
response to cadmium ion	Cyclin-dependent kinase 1	Homo sapiens (human)
response to copper ion	Cyclin-dependent kinase 1	Homo sapiens (human)
symbiont entry into host cell	Cyclin-dependent kinase 1	Homo sapiens (human)
fibroblast proliferation	Cyclin-dependent kinase 1	Homo sapiens (human)
rhythmic process	Cyclin-dependent kinase 1	Homo sapiens (human)
response to axon injury	Cyclin-dependent kinase 1	Homo sapiens (human)
cell division	Cyclin-dependent kinase 1	Homo sapiens (human)
ventricular cardiac muscle cell development	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of cardiac muscle cell proliferation	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of mitotic sister chromatid segregation	Cyclin-dependent kinase 1	Homo sapiens (human)
protein-containing complex assembly	Cyclin-dependent kinase 1	Homo sapiens (human)
cellular response to hydrogen peroxide	Cyclin-dependent kinase 1	Homo sapiens (human)
ERK1 and ERK2 cascade	Cyclin-dependent kinase 1	Homo sapiens (human)
cellular response to organic cyclic compound	Cyclin-dependent kinase 1	Homo sapiens (human)
Golgi disassembly	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of protein localization to nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
regulation of attachment of mitotic spindle microtubules to kinetochore	Cyclin-dependent kinase 1	Homo sapiens (human)
microtubule cytoskeleton organization involved in mitosis	Cyclin-dependent kinase 1	Homo sapiens (human)
positive regulation of mitochondrial ATP synthesis coupled electron transport	Cyclin-dependent kinase 1	Homo sapiens (human)
mitotic G2 DNA damage checkpoint signaling	Cyclin-dependent kinase 1	Homo sapiens (human)
protein deubiquitination	Cyclin-dependent kinase 1	Homo sapiens (human)
DNA damage checkpoint signaling	Tyrosine-protein kinase Lyn	Homo sapiens (human)
B cell homeostasis	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of cytokine production	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
hematopoietic progenitor cell differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc receptor mediated stimulatory signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
tolerance induction to self antigen	Tyrosine-protein kinase Lyn	Homo sapiens (human)
histamine secretion by mast cell	Tyrosine-protein kinase Lyn	Homo sapiens (human)
platelet degranulation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of myeloid leukocyte differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
immune response-regulating cell surface receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc receptor mediated inhibitory signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of B cell apoptotic process	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
DNA damage response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to sterol depletion	Tyrosine-protein kinase Lyn	Homo sapiens (human)
signal transduction	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of cell population proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of cell population proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to xenobiotic stimulus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to toxic substance	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to hormone	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to carbohydrate	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of neuron projection development	Tyrosine-protein kinase Lyn	Homo sapiens (human)
oligodendrocyte development	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to organic cyclic compound	Tyrosine-protein kinase Lyn	Homo sapiens (human)
fatty acid transport	Tyrosine-protein kinase Lyn	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
erythrocyte differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
eosinophil differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of cell migration	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of B cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to insulin	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of mast cell activation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of cell adhesion mediated by integrin	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of toll-like receptor 2 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
toll-like receptor 4 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of toll-like receptor 4 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cellular response to heat	Tyrosine-protein kinase Lyn	Homo sapiens (human)
interleukin-5-mediated signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase Lyn	Homo sapiens (human)
C-X-C chemokine receptor CXCR4 signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to amino acid	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of mast cell degranulation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of MAP kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of MAPK cascade	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of erythrocyte differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ephrin receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
response to axon injury	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of immune response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of B cell receptor signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
leukocyte migration	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of glial cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of Fc receptor mediated stimulatory signaling pathway	Tyrosine-protein kinase Lyn	Homo sapiens (human)
growth hormone receptor signaling pathway via JAK-STAT	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of oligodendrocyte progenitor proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of mast cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of mast cell proliferation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cellular response to retinoic acid	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of monocyte chemotaxis	Tyrosine-protein kinase Lyn	Homo sapiens (human)
regulation of platelet aggregation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
dendritic cell differentiation	Tyrosine-protein kinase Lyn	Homo sapiens (human)
negative regulation of intracellular signal transduction	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	Tyrosine-protein kinase Lyn	Homo sapiens (human)
positive regulation of dendritic cell apoptotic process	Tyrosine-protein kinase Lyn	Homo sapiens (human)
neuron projection development	Tyrosine-protein kinase Lyn	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Lyn	Homo sapiens (human)
endothelial cell morphogenesis	Hepatocyte growth factor receptor	Homo sapiens (human)
signal transduction	Hepatocyte growth factor receptor	Homo sapiens (human)
cell surface receptor signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of autophagy	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of microtubule polymerization	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of Rho protein signal transduction	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Hepatocyte growth factor receptor	Homo sapiens (human)
hepatocyte growth factor receptor signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
branching morphogenesis of an epithelial tube	Hepatocyte growth factor receptor	Homo sapiens (human)
positive chemotaxis	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of stress fiber assembly	Hepatocyte growth factor receptor	Homo sapiens (human)
excitatory postsynaptic potential	Hepatocyte growth factor receptor	Homo sapiens (human)
establishment of skin barrier	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of thrombin-activated receptor signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
semaphorin-plexin signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of hydrogen peroxide-mediated programmed cell death	Hepatocyte growth factor receptor	Homo sapiens (human)
negative regulation of guanyl-nucleotide exchange factor activity	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Hepatocyte growth factor receptor	Homo sapiens (human)
liver development	Hepatocyte growth factor receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Hepatocyte growth factor receptor	Homo sapiens (human)
phagocytosis	Hepatocyte growth factor receptor	Homo sapiens (human)
multicellular organism development	Hepatocyte growth factor receptor	Homo sapiens (human)
neuron differentiation	Hepatocyte growth factor receptor	Homo sapiens (human)
positive regulation of kinase activity	Hepatocyte growth factor receptor	Homo sapiens (human)
cell migration	Hepatocyte growth factor receptor	Homo sapiens (human)
pancreas development	Hepatocyte growth factor receptor	Homo sapiens (human)
nervous system development	Hepatocyte growth factor receptor	Homo sapiens (human)
leukocyte migration involved in immune response	Tyrosine-protein kinase HCK	Homo sapiens (human)
innate immune response-activating signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase HCK	Homo sapiens (human)
inflammatory response	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell adhesion	Tyrosine-protein kinase HCK	Homo sapiens (human)
integrin-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
mesoderm development	Tyrosine-protein kinase HCK	Homo sapiens (human)
positive regulation of cell population proliferation	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of cell shape	Tyrosine-protein kinase HCK	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytokine-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
positive regulation of actin filament polymerization	Tyrosine-protein kinase HCK	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of actin cytoskeleton organization	Tyrosine-protein kinase HCK	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase HCK	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Tyrosine-protein kinase HCK	Homo sapiens (human)
negative regulation of apoptotic process	Tyrosine-protein kinase HCK	Homo sapiens (human)
leukocyte degranulation	Tyrosine-protein kinase HCK	Homo sapiens (human)
respiratory burst after phagocytosis	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein autophosphorylation	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of inflammatory response	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of phagocytosis	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of DNA-binding transcription factor activity	Tyrosine-protein kinase HCK	Homo sapiens (human)
type II interferon-mediated signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
regulation of podosome assembly	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase HCK	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase HCK	Homo sapiens (human)
signal transduction	Platelet-derived growth factor receptor beta	Homo sapiens (human)
G protein-coupled receptor signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cell population proliferation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of phospholipase C activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of smooth muscle cell migration	Platelet-derived growth factor receptor beta	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cell migration	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of phosphoprotein phosphatase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
regulation of actin cytoskeleton organization	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell migration involved in vasculogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor-beta signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
aorta morphogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of MAP kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of mitotic nuclear division	Platelet-derived growth factor receptor beta	Homo sapiens (human)
phosphatidylinositol metabolic process	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein autophosphorylation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of smooth muscle cell proliferation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of chemotaxis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cardiac myofibril assembly	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell chemotaxis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell migration involved in coronary angiogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
retina vasculature development in camera-type eye	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Platelet-derived growth factor receptor beta	Homo sapiens (human)
smooth muscle cell chemotaxis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
metanephric glomerular mesangial cell proliferation involved in metanephros development	Platelet-derived growth factor receptor beta	Homo sapiens (human)
metanephric glomerular capillary formation	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of calcium ion import	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of DNA biosynthetic process	Platelet-derived growth factor receptor beta	Homo sapiens (human)
positive regulation of kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
angiogenesis	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Platelet-derived growth factor receptor beta	Homo sapiens (human)
multicellular organism development	Platelet-derived growth factor receptor beta	Homo sapiens (human)
xenobiotic metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
steroid metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
cholesterol metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
estrogen metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
coumarin metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
alkaloid metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
alkaloid catabolic process	Cytochrome P450 2D6	Homo sapiens (human)
monoterpenoid metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
isoquinoline alkaloid metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
xenobiotic catabolic process	Cytochrome P450 2D6	Homo sapiens (human)
retinol metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
long-chain fatty acid biosynthetic process	Cytochrome P450 2D6	Homo sapiens (human)
negative regulation of binding	Cytochrome P450 2D6	Homo sapiens (human)
oxidative demethylation	Cytochrome P450 2D6	Homo sapiens (human)
negative regulation of cellular organofluorine metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
arachidonic acid metabolic process	Cytochrome P450 2D6	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
primary ovarian follicle growth	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of cytokine production	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
stimulatory C-type lectin receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of inflammatory response to antigenic stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
signal complex assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
epidermal growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
integrin-mediated signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
spermatogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
learning or memory	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to xenobiotic stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to mechanical stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to acidic pH	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of gene expression	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of epithelial cell migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of epithelial cell migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of glucose metabolic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein processing	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
skeletal muscle cell proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of smooth muscle cell migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
macroautophagy	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of cell-cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
platelet activation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
forebrain development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
T cell costimulation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein destabilization	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to nutrient levels	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of telomere maintenance via telomerase	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to insulin stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of intracellular estrogen receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of integrin activation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of toll-like receptor 3 signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
adherens junction organization	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of dephosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of hippo signaling	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
intracellular signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
entry of bacterium into host cell	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
osteoclast development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to platelet-derived growth factor stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ERBB2 signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
angiotensin-activated signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
odontogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of apoptotic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of apoptotic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of vascular permeability	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
stress fiber assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
transcytosis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of bone resorption	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
bone resorption	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of Notch signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of bone resorption	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of Ras protein signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of insulin receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein autophosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
neurotrophin TRK receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ephrin receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
focal adhesion assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
oogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
progesterone receptor signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
leukocyte migration	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of small GTPase mediated signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein transport	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to mineralocorticoid	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
myoblast proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to electrical stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of focal adhesion assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of mitochondrial depolarization	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of telomerase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
uterus development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
branching involved in mammary gland duct morphogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of cell projection assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
intestinal epithelial cell development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
interleukin-6-mediated signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to hydrogen peroxide	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
response to interleukin-1	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to lipopolysaccharide	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to peptide hormone stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to progesterone stimulus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to fatty acid	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to hypoxia	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to fluid shear stress	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of podosome assembly	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
DNA biosynthetic process	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein serine/threonine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of heart rate by cardiac conduction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of canonical Wnt signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell-cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of protein localization to nucleus	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of non-membrane spanning protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of TORC1 signaling	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of vascular associated smooth muscle cell proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to prolactin	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of male germ cell proliferation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of ovarian follicle development	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of lamellipodium morphogenesis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
positive regulation of platelet-derived growth factor receptor-beta signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of early endosome to late endosome transport	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of anoikis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of extrinsic apoptotic signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
negative regulation of intrinsic apoptotic signaling pathway	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
regulation of caveolin-mediated endocytosis	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell differentiation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
innate immune response	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein phosphorylation	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
symbiont entry into host cell	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cellular response to reactive oxygen species	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
luteinization	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
in utero embryonic development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell activation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
hematopoietic progenitor cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
estrogen metabolic process	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of cell population proliferation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
negative regulation of platelet activation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of phospholipase C activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
signal transduction involved in regulation of gene expression	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
extracellular matrix organization	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
lung development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
adrenal gland development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of cell migration	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
male genitalia development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
regulation of actin cytoskeleton organization	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
Leydig cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor receptor-alpha signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
wound healing	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
odontogenesis of dentin-containing tooth	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein autophosphorylation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor receptor signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of fibroblast proliferation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
embryonic digestive tract morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
embryonic cranial skeleton morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
embryonic skeletal system morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
white fat cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of chemotaxis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cardiac myofibril assembly	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
roof of mouth development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
face morphogenesis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell chemotaxis	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
retina vasculature development in camera-type eye	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet aggregation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cellular response to amino acid stimulus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
metanephric glomerular capillary formation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
regulation of mesenchymal stem cell differentiation	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
positive regulation of kinase activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
multicellular organism development	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
angiogenesis	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Protein kinase C alpha type	Homo sapiens (human)
desmosome assembly	Protein kinase C alpha type	Homo sapiens (human)
chromatin remodeling	Protein kinase C alpha type	Homo sapiens (human)
protein phosphorylation	Protein kinase C alpha type	Homo sapiens (human)
mitotic nuclear membrane disassembly	Protein kinase C alpha type	Homo sapiens (human)
cell adhesion	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of endothelial cell migration	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of cardiac muscle hypertrophy	Protein kinase C alpha type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C alpha type	Homo sapiens (human)
peptidyl-threonine phosphorylation	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of cell migration	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of lipopolysaccharide-mediated signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C alpha type	Homo sapiens (human)
regulation of mRNA stability	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Protein kinase C alpha type	Homo sapiens (human)
post-translational protein modification	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of macrophage differentiation	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of angiogenesis	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of bone resorption	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of cell adhesion	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of mitotic cell cycle	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Protein kinase C alpha type	Homo sapiens (human)
response to interleukin-1	Protein kinase C alpha type	Homo sapiens (human)
regulation of platelet aggregation	Protein kinase C alpha type	Homo sapiens (human)
apoptotic signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of angiotensin-activated signaling pathway	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of dense core granule biogenesis	Protein kinase C alpha type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C alpha type	Homo sapiens (human)
positive regulation of insulin secretion	Protein kinase C alpha type	Homo sapiens (human)
protein phosphorylation	Protein kinase C eta type	Homo sapiens (human)
signal transduction	Protein kinase C eta type	Homo sapiens (human)
positive regulation of macrophage derived foam cell differentiation	Protein kinase C eta type	Homo sapiens (human)
cell differentiation	Protein kinase C eta type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C eta type	Homo sapiens (human)
positive regulation of keratinocyte differentiation	Protein kinase C eta type	Homo sapiens (human)
positive regulation of B cell receptor signaling pathway	Protein kinase C eta type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C eta type	Homo sapiens (human)
positive regulation of glial cell proliferation	Protein kinase C eta type	Homo sapiens (human)
protein kinase C signaling	Protein kinase C eta type	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Protein kinase C eta type	Homo sapiens (human)
regulation of bicellular tight junction assembly	Protein kinase C eta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C eta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C eta type	Homo sapiens (human)
branching involved in blood vessel morphogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of macroautophagy	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of mitochondrial depolarization	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of mitochondrial fission	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
ovarian follicle development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vasculogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of protein phosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
lymph vessel development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell migration involved in sprouting angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of mesenchymal cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
epithelial cell maturation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endocardium development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endothelium development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of cell population proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of cell shape	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
mesenchymal cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of endothelial cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
negative regulation of gene expression	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of BMP signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
embryonic hemopoiesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor receptor-2 signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
peptidyl-tyrosine autophosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
surfactant homeostasis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of MAPK cascade	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
negative regulation of neuron apoptotic process	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell fate commitment	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
protein autophosphorylation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
lung alveolus development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
post-embryonic camera-type eye morphogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
epithelial cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of positive chemotaxis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of nitric-oxide synthase biosynthetic process	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of focal adhesion assembly	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
calcium ion homeostasis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
blood vessel endothelial cell differentiation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular wound healing	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
semaphorin-plexin signaling pathway	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
stem cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of cell migration involved in sprouting angiogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of hematopoietic progenitor cell differentiation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of bone development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cellular response to hydrogen sulfide	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of stem cell proliferation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of vasculogenesis	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
regulation of MAPK cascade	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
multicellular organism development	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell migration	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endothelial cell differentiation	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
positive regulation of kinase activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
hemopoiesis	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
leukocyte homeostasis	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
myeloid progenitor cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
pro-B cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of cell population proliferation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
response to organonitrogen compound	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cytokine-mediated signaling pathway	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
B cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
animal organ regeneration	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
common myeloid progenitor cell proliferation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
vascular endothelial growth factor signaling pathway	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of tyrosine phosphorylation of STAT protein	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
regulation of apoptotic process	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of MAP kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of MAPK cascade	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
lymphocyte proliferation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein autophosphorylation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cellular response to cytokine stimulus	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cellular response to glucocorticoid stimulus	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
dendritic cell differentiation	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
positive regulation of kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
multicellular organism development	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of cell population proliferation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of low-density lipoprotein particle clearance	Tyrosine-protein kinase CSK	Homo sapiens (human)
T cell costimulation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of interleukin-6 production	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of Golgi to plasma membrane protein transport	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of bone resorption	Tyrosine-protein kinase CSK	Homo sapiens (human)
oligodendrocyte differentiation	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of phagocytosis	Tyrosine-protein kinase CSK	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase CSK	Homo sapiens (human)
negative regulation of ERK1 and ERK2 cascade	Tyrosine-protein kinase CSK	Homo sapiens (human)
cellular response to peptide hormone stimulus	Tyrosine-protein kinase CSK	Homo sapiens (human)
regulation of Fc receptor mediated stimulatory signaling pathway	Tyrosine-protein kinase CSK	Homo sapiens (human)
adherens junction organization	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein phosphorylation	Protein kinase C iota type	Homo sapiens (human)
protein targeting to membrane	Protein kinase C iota type	Homo sapiens (human)
cytoskeleton organization	Protein kinase C iota type	Homo sapiens (human)
actin filament organization	Protein kinase C iota type	Homo sapiens (human)
positive regulation of neuron projection development	Protein kinase C iota type	Homo sapiens (human)
vesicle-mediated transport	Protein kinase C iota type	Homo sapiens (human)
cell migration	Protein kinase C iota type	Homo sapiens (human)
cellular response to insulin stimulus	Protein kinase C iota type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C iota type	Homo sapiens (human)
establishment of apical/basal cell polarity	Protein kinase C iota type	Homo sapiens (human)
eye photoreceptor cell development	Protein kinase C iota type	Homo sapiens (human)
negative regulation of apoptotic process	Protein kinase C iota type	Homo sapiens (human)
negative regulation of neuron apoptotic process	Protein kinase C iota type	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Protein kinase C iota type	Homo sapiens (human)
cell-cell junction organization	Protein kinase C iota type	Homo sapiens (human)
positive regulation of Notch signaling pathway	Protein kinase C iota type	Homo sapiens (human)
positive regulation of glucose import	Protein kinase C iota type	Homo sapiens (human)
secretion	Protein kinase C iota type	Homo sapiens (human)
Golgi vesicle budding	Protein kinase C iota type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C iota type	Homo sapiens (human)
positive regulation of glial cell proliferation	Protein kinase C iota type	Homo sapiens (human)
membrane organization	Protein kinase C iota type	Homo sapiens (human)
cellular response to chemical stress	Protein kinase C iota type	Homo sapiens (human)
response to interleukin-1	Protein kinase C iota type	Homo sapiens (human)
regulation of postsynaptic membrane neurotransmitter receptor levels	Protein kinase C iota type	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Protein kinase C iota type	Homo sapiens (human)
positive regulation of endothelial cell apoptotic process	Protein kinase C iota type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C iota type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C iota type	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive thymic T cell selection	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive regulation of T cell differentiation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
adaptive immune response	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
immune response	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
calcium-mediated signaling	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell differentiation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell activation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
B cell activation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
beta selection	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
negative thymic T cell selection	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive regulation of alpha-beta T cell differentiation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive regulation of alpha-beta T cell proliferation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
positive regulation of calcium-mediated signaling	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell receptor signaling pathway	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell aggregation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell migration	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
peptidyl-tyrosine phosphorylation	Tyrosine-protein kinase Blk	Homo sapiens (human)
positive regulation of insulin secretion	Tyrosine-protein kinase Blk	Homo sapiens (human)
positive regulation of protein binding	Tyrosine-protein kinase Blk	Homo sapiens (human)
intracellular signal transduction	Tyrosine-protein kinase Blk	Homo sapiens (human)
B cell receptor signaling pathway	Tyrosine-protein kinase Blk	Homo sapiens (human)
innate immune response	Tyrosine-protein kinase Blk	Homo sapiens (human)
protein phosphorylation	Tyrosine-protein kinase Blk	Homo sapiens (human)
cell differentiation	Tyrosine-protein kinase Blk	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Tyrosine-protein kinase Blk	Homo sapiens (human)
MAPK cascade	Protein kinase C epsilon type	Homo sapiens (human)
macrophage activation involved in immune response	Protein kinase C epsilon type	Homo sapiens (human)
protein phosphorylation	Protein kinase C epsilon type	Homo sapiens (human)
apoptotic process	Protein kinase C epsilon type	Homo sapiens (human)
signal transduction	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of epithelial cell migration	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of fibroblast migration	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of cell-substrate adhesion	Protein kinase C epsilon type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C epsilon type	Homo sapiens (human)
insulin secretion	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of actin filament polymerization	Protein kinase C epsilon type	Homo sapiens (human)
negative regulation of protein ubiquitination	Protein kinase C epsilon type	Homo sapiens (human)
cell-substrate adhesion	Protein kinase C epsilon type	Homo sapiens (human)
lipopolysaccharide-mediated signaling pathway	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of insulin secretion	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of synaptic transmission, GABAergic	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of cytokinesis	Protein kinase C epsilon type	Homo sapiens (human)
locomotory exploration behavior	Protein kinase C epsilon type	Homo sapiens (human)
TRAM-dependent toll-like receptor 4 signaling pathway	Protein kinase C epsilon type	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Protein kinase C epsilon type	Homo sapiens (human)
response to morphine	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of MAPK cascade	Protein kinase C epsilon type	Homo sapiens (human)
regulation of peptidyl-tyrosine phosphorylation	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of lipid catabolic process	Protein kinase C epsilon type	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol	Protein kinase C epsilon type	Homo sapiens (human)
cell division	Protein kinase C epsilon type	Homo sapiens (human)
establishment of localization in cell	Protein kinase C epsilon type	Homo sapiens (human)
synaptic transmission, GABAergic	Protein kinase C epsilon type	Homo sapiens (human)
regulation of insulin secretion involved in cellular response to glucose stimulus	Protein kinase C epsilon type	Homo sapiens (human)
mucus secretion	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of mucus secretion	Protein kinase C epsilon type	Homo sapiens (human)
cellular response to ethanol	Protein kinase C epsilon type	Homo sapiens (human)
cellular response to prostaglandin E stimulus	Protein kinase C epsilon type	Homo sapiens (human)
cellular response to hypoxia	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of wound healing	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of protein localization to plasma membrane	Protein kinase C epsilon type	Homo sapiens (human)
negative regulation of sodium ion transmembrane transporter activity	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of cellular glucuronidation	Protein kinase C epsilon type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C epsilon type	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Angiopoietin-1 receptor	Homo sapiens (human)
angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
response to hypoxia	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of protein phosphorylation	Angiopoietin-1 receptor	Homo sapiens (human)
endothelial cell proliferation	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Angiopoietin-1 receptor	Homo sapiens (human)
endochondral ossification	Angiopoietin-1 receptor	Homo sapiens (human)
sprouting angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
cell surface receptor protein tyrosine kinase signaling pathway	Angiopoietin-1 receptor	Homo sapiens (human)
cell-cell signaling	Angiopoietin-1 receptor	Homo sapiens (human)
heart development	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of endothelial cell migration	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of establishment or maintenance of cell polarity	Angiopoietin-1 receptor	Homo sapiens (human)
substrate adhesion-dependent cell spreading	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of Rac protein signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of Rho protein signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of apoptotic process	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of vascular permeability	Angiopoietin-1 receptor	Homo sapiens (human)
response to peptide hormone	Angiopoietin-1 receptor	Homo sapiens (human)
response to estrogen	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of angiogenesis	Angiopoietin-1 receptor	Homo sapiens (human)
Tie signaling pathway	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of inflammatory response	Angiopoietin-1 receptor	Homo sapiens (human)
response to cAMP	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of focal adhesion assembly	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
definitive hemopoiesis	Angiopoietin-1 receptor	Homo sapiens (human)
heart trabecula formation	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Angiopoietin-1 receptor	Homo sapiens (human)
glomerulus vasculature development	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of intracellular signal transduction	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of endothelial cell apoptotic process	Angiopoietin-1 receptor	Homo sapiens (human)
negative regulation of endothelial cell apoptotic process	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of MAPK cascade	Angiopoietin-1 receptor	Homo sapiens (human)
positive regulation of kinase activity	Angiopoietin-1 receptor	Homo sapiens (human)
multicellular organism development	Angiopoietin-1 receptor	Homo sapiens (human)
regulation of cell growth	Protein kinase C theta type	Homo sapiens (human)
regulation of DNA-templated transcription	Protein kinase C theta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C theta type	Homo sapiens (human)
membrane protein ectodomain proteolysis	Protein kinase C theta type	Homo sapiens (human)
inflammatory response	Protein kinase C theta type	Homo sapiens (human)
axon guidance	Protein kinase C theta type	Homo sapiens (human)
positive regulation of telomere maintenance via telomerase	Protein kinase C theta type	Homo sapiens (human)
positive regulation of interleukin-17 production	Protein kinase C theta type	Homo sapiens (human)
positive regulation of interleukin-2 production	Protein kinase C theta type	Homo sapiens (human)
positive regulation of interleukin-4 production	Protein kinase C theta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C theta type	Homo sapiens (human)
CD4-positive, alpha-beta T cell proliferation	Protein kinase C theta type	Homo sapiens (human)
Fc-epsilon receptor signaling pathway	Protein kinase C theta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C theta type	Homo sapiens (human)
positive regulation of T cell activation	Protein kinase C theta type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C theta type	Homo sapiens (human)
positive regulation of telomerase activity	Protein kinase C theta type	Homo sapiens (human)
cell chemotaxis	Protein kinase C theta type	Homo sapiens (human)
negative regulation of T cell apoptotic process	Protein kinase C theta type	Homo sapiens (human)
regulation of platelet aggregation	Protein kinase C theta type	Homo sapiens (human)
positive regulation of telomere capping	Protein kinase C theta type	Homo sapiens (human)
positive regulation of T-helper 17 type immune response	Protein kinase C theta type	Homo sapiens (human)
positive regulation of CD4-positive, alpha-beta T cell proliferation	Protein kinase C theta type	Homo sapiens (human)
positive regulation of T-helper 2 cell activation	Protein kinase C theta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C theta type	Homo sapiens (human)
microtubule cytoskeleton organization	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of cell-matrix adhesion	Protein kinase C zeta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C zeta type	Homo sapiens (human)
inflammatory response	Protein kinase C zeta type	Homo sapiens (human)
signal transduction	Protein kinase C zeta type	Homo sapiens (human)
cell surface receptor signaling pathway	Protein kinase C zeta type	Homo sapiens (human)
long-term memory	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of cell population proliferation	Protein kinase C zeta type	Homo sapiens (human)
cell migration	Protein kinase C zeta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C zeta type	Homo sapiens (human)
establishment of cell polarity	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of protein-containing complex assembly	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-10 production	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-13 production	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-4 production	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of interleukin-5 production	Protein kinase C zeta type	Homo sapiens (human)
cellular response to insulin stimulus	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of apoptotic process	Protein kinase C zeta type	Homo sapiens (human)
establishment or maintenance of epithelial cell apical/basal polarity	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of T-helper 2 cell differentiation	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of insulin receptor signaling pathway	Protein kinase C zeta type	Homo sapiens (human)
vesicle transport along microtubule	Protein kinase C zeta type	Homo sapiens (human)
negative regulation of peptidyl-tyrosine phosphorylation	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of protein transport	Protein kinase C zeta type	Homo sapiens (human)
membrane depolarization	Protein kinase C zeta type	Homo sapiens (human)
membrane hyperpolarization	Protein kinase C zeta type	Homo sapiens (human)
long-term synaptic potentiation	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of ERK1 and ERK2 cascade	Protein kinase C zeta type	Homo sapiens (human)
protein kinase C signaling	Protein kinase C zeta type	Homo sapiens (human)
protein localization to plasma membrane	Protein kinase C zeta type	Homo sapiens (human)
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	Protein kinase C zeta type	Homo sapiens (human)
neuron projection extension	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of excitatory postsynaptic potential	Protein kinase C zeta type	Homo sapiens (human)
positive regulation of T-helper 2 cell cytokine production	Protein kinase C zeta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C zeta type	Homo sapiens (human)
protein phosphorylation	Protein kinase C delta type	Homo sapiens (human)
apoptotic process	Protein kinase C delta type	Homo sapiens (human)
DNA damage response	Protein kinase C delta type	Homo sapiens (human)
signal transduction	Protein kinase C delta type	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to oxidative stress	Protein kinase C delta type	Homo sapiens (human)
regulation of signaling receptor activity	Protein kinase C delta type	Homo sapiens (human)
immunoglobulin mediated immune response	Protein kinase C delta type	Homo sapiens (human)
peptidyl-serine phosphorylation	Protein kinase C delta type	Homo sapiens (human)
peptidyl-threonine phosphorylation	Protein kinase C delta type	Homo sapiens (human)
termination of signal transduction	Protein kinase C delta type	Homo sapiens (human)
negative regulation of actin filament polymerization	Protein kinase C delta type	Homo sapiens (human)
positive regulation of endodeoxyribonuclease activity	Protein kinase C delta type	Homo sapiens (human)
negative regulation of protein binding	Protein kinase C delta type	Homo sapiens (human)
activation of protein kinase activity	Protein kinase C delta type	Homo sapiens (human)
positive regulation of superoxide anion generation	Protein kinase C delta type	Homo sapiens (human)
regulation of actin cytoskeleton organization	Protein kinase C delta type	Homo sapiens (human)
negative regulation of glial cell apoptotic process	Protein kinase C delta type	Homo sapiens (human)
cellular response to UV	Protein kinase C delta type	Homo sapiens (human)
positive regulation of protein dephosphorylation	Protein kinase C delta type	Homo sapiens (human)
Fc-gamma receptor signaling pathway involved in phagocytosis	Protein kinase C delta type	Homo sapiens (human)
B cell proliferation	Protein kinase C delta type	Homo sapiens (human)
neutrophil activation	Protein kinase C delta type	Homo sapiens (human)
positive regulation of protein import into nucleus	Protein kinase C delta type	Homo sapiens (human)
defense response to bacterium	Protein kinase C delta type	Homo sapiens (human)
negative regulation of MAP kinase activity	Protein kinase C delta type	Homo sapiens (human)
regulation of mRNA stability	Protein kinase C delta type	Homo sapiens (human)
post-translational protein modification	Protein kinase C delta type	Homo sapiens (human)
negative regulation of insulin receptor signaling pathway	Protein kinase C delta type	Homo sapiens (human)
negative regulation of inflammatory response	Protein kinase C delta type	Homo sapiens (human)
negative regulation of peptidyl-tyrosine phosphorylation	Protein kinase C delta type	Homo sapiens (human)
protein stabilization	Protein kinase C delta type	Homo sapiens (human)
negative regulation of filopodium assembly	Protein kinase C delta type	Homo sapiens (human)
cell chemotaxis	Protein kinase C delta type	Homo sapiens (human)
cellular response to hydrogen peroxide	Protein kinase C delta type	Homo sapiens (human)
cellular response to hydroperoxide	Protein kinase C delta type	Homo sapiens (human)
negative regulation of platelet aggregation	Protein kinase C delta type	Homo sapiens (human)
cellular senescence	Protein kinase C delta type	Homo sapiens (human)
positive regulation of phospholipid scramblase activity	Protein kinase C delta type	Homo sapiens (human)
cellular response to angiotensin	Protein kinase C delta type	Homo sapiens (human)
regulation of ceramide biosynthetic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of ceramide biosynthetic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of glucosylceramide catabolic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of sphingomyelin catabolic process	Protein kinase C delta type	Homo sapiens (human)
positive regulation of apoptotic signaling pathway	Protein kinase C delta type	Homo sapiens (human)
intracellular signal transduction	Protein kinase C delta type	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
angiogenesis	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of endothelial cell proliferation	Serine/threonine-protein kinase D1	Homo sapiens (human)
apoptotic process	Serine/threonine-protein kinase D1	Homo sapiens (human)
inflammatory response	Serine/threonine-protein kinase D1	Homo sapiens (human)
Golgi organization	Serine/threonine-protein kinase D1	Homo sapiens (human)
signal transduction	Serine/threonine-protein kinase D1	Homo sapiens (human)
integrin-mediated signaling pathway	Serine/threonine-protein kinase D1	Homo sapiens (human)
nervous system development	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of autophagy	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of endothelial cell migration	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of gene expression	Serine/threonine-protein kinase D1	Homo sapiens (human)
regulation of keratinocyte proliferation	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of neuron projection development	Serine/threonine-protein kinase D1	Homo sapiens (human)
regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril	Serine/threonine-protein kinase D1	Homo sapiens (human)
peptidyl-serine phosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
peptidyl-threonine phosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
sphingolipid biosynthetic process	Serine/threonine-protein kinase D1	Homo sapiens (human)
cell differentiation	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of peptidyl-serine phosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to amino acid starvation	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to oxidative stress	Serine/threonine-protein kinase D1	Homo sapiens (human)
intracellular signal transduction	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to vascular endothelial growth factor stimulus	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of protein import into nucleus	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of canonical NF-kappaB signal transduction	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of blood vessel endothelial cell migration	Serine/threonine-protein kinase D1	Homo sapiens (human)
innate immune response	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of osteoblast differentiation	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of angiogenesis	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of cell size	Serine/threonine-protein kinase D1	Homo sapiens (human)
negative regulation of endocytosis	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Serine/threonine-protein kinase D1	Homo sapiens (human)
protein autophosphorylation	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of protein export from nucleus	Serine/threonine-protein kinase D1	Homo sapiens (human)
vascular endothelial growth factor receptor signaling pathway	Serine/threonine-protein kinase D1	Homo sapiens (human)
Golgi vesicle transport	Serine/threonine-protein kinase D1	Homo sapiens (human)
defense response to Gram-negative bacterium	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of NF-kappaB transcription factor activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
regulation of release of sequestered calcium ion into cytosol	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of sarcomere organization	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to hydroperoxide	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to norepinephrine stimulus	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of peptide hormone secretion	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of NLRP3 inflammasome complex assembly	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to angiotensin	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to phorbol 13-acetate 12-myristate	Serine/threonine-protein kinase D1	Homo sapiens (human)
cellular response to endothelin	Serine/threonine-protein kinase D1	Homo sapiens (human)
positive regulation of endothelial cell chemotaxis	Serine/threonine-protein kinase D1	Homo sapiens (human)
regulation of integrin-mediated signaling pathway	Serine/threonine-protein kinase D1	Homo sapiens (human)
phospholipase C-activating G protein-coupled receptor signaling pathway	Serine/threonine-protein kinase D1	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Molecular Functions (122)

Process	via Protein(s)	Taxonomy
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase D3	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase D3	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase D3	Homo sapiens (human)
cytokine activity	Interferon beta	Homo sapiens (human)
cytokine receptor binding	Interferon beta	Homo sapiens (human)
type I interferon receptor binding	Interferon beta	Homo sapiens (human)
protein binding	Interferon beta	Homo sapiens (human)
chloramphenicol O-acetyltransferase activity	Interferon beta	Homo sapiens (human)
protein kinase activity	Protein kinase C gamma type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C gamma type	Homo sapiens (human)
calcium,diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C gamma type	Homo sapiens (human)
protein serine/threonine/tyrosine kinase activity	Protein kinase C gamma type	Homo sapiens (human)
protein binding	Protein kinase C gamma type	Homo sapiens (human)
ATP binding	Protein kinase C gamma type	Homo sapiens (human)
zinc ion binding	Protein kinase C gamma type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C gamma type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C gamma type	Homo sapiens (human)
chromatin binding	Protein kinase C beta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C beta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C beta type	Homo sapiens (human)
protein kinase C binding	Protein kinase C beta type	Homo sapiens (human)
calcium channel regulator activity	Protein kinase C beta type	Homo sapiens (human)
protein binding	Protein kinase C beta type	Homo sapiens (human)
ATP binding	Protein kinase C beta type	Homo sapiens (human)
zinc ion binding	Protein kinase C beta type	Homo sapiens (human)
nuclear receptor coactivator activity	Protein kinase C beta type	Homo sapiens (human)
histone H3T6 kinase activity	Protein kinase C beta type	Homo sapiens (human)
histone binding	Protein kinase C beta type	Homo sapiens (human)
nuclear androgen receptor binding	Protein kinase C beta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C beta type	Homo sapiens (human)
amyloid-beta binding	Insulin receptor	Homo sapiens (human)
protein tyrosine kinase activity	Insulin receptor	Homo sapiens (human)
insulin receptor activity	Insulin receptor	Homo sapiens (human)
insulin-like growth factor receptor binding	Insulin receptor	Homo sapiens (human)
protein binding	Insulin receptor	Homo sapiens (human)
ATP binding	Insulin receptor	Homo sapiens (human)
GTP binding	Insulin receptor	Homo sapiens (human)
protein domain specific binding	Insulin receptor	Homo sapiens (human)
insulin-like growth factor I binding	Insulin receptor	Homo sapiens (human)
insulin-like growth factor II binding	Insulin receptor	Homo sapiens (human)
cargo receptor activity	Insulin receptor	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Insulin receptor	Homo sapiens (human)
insulin binding	Insulin receptor	Homo sapiens (human)
insulin receptor substrate binding	Insulin receptor	Homo sapiens (human)
protein-containing complex binding	Insulin receptor	Homo sapiens (human)
PTB domain binding	Insulin receptor	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein serine/threonine phosphatase activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
phospholipase activator activity	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein kinase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein phosphatase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
SH2 domain binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
T cell receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
CD4 receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
CD8 receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
phosphatidylinositol 3-kinase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
ATPase binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Lck	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
phospholipase activator activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
enzyme binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
type 5 metabotropic glutamate receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
alpha-tubulin binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
phospholipase binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
transmembrane transporter binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
ephrin receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
tau protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
tau-protein kinase activity	Tyrosine-protein kinase Fyn	Homo sapiens (human)
growth factor receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
scaffold protein binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
disordered domain specific binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Fyn	Homo sapiens (human)
virus receptor activity	Cyclin-dependent kinase 1	Homo sapiens (human)
chromatin binding	Cyclin-dependent kinase 1	Homo sapiens (human)
protein kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein serine/threonine kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin-dependent protein serine/threonine kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein binding	Cyclin-dependent kinase 1	Homo sapiens (human)
ATP binding	Cyclin-dependent kinase 1	Homo sapiens (human)
RNA polymerase II CTD heptapeptide repeat kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin binding	Cyclin-dependent kinase 1	Homo sapiens (human)
Hsp70 protein binding	Cyclin-dependent kinase 1	Homo sapiens (human)
histone kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin-dependent protein kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein serine kinase activity	Cyclin-dependent kinase 1	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
platelet-derived growth factor receptor binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
integrin binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
kinase activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
SH3 domain binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ubiquitin protein ligase binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
gamma-tubulin binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
glycosphingolipid binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
transmembrane transporter binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
ephrin receptor binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
phosphoprotein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
scaffold protein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
phosphorylation-dependent protein binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
phosphatidylinositol 3-kinase activator activity	Tyrosine-protein kinase Lyn	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Lyn	Homo sapiens (human)
protein tyrosine kinase activity	Hepatocyte growth factor receptor	Homo sapiens (human)
protein binding	Hepatocyte growth factor receptor	Homo sapiens (human)
ATP binding	Hepatocyte growth factor receptor	Homo sapiens (human)
semaphorin receptor activity	Hepatocyte growth factor receptor	Homo sapiens (human)
protein phosphatase binding	Hepatocyte growth factor receptor	Homo sapiens (human)
identical protein binding	Hepatocyte growth factor receptor	Homo sapiens (human)
molecular function activator activity	Hepatocyte growth factor receptor	Homo sapiens (human)
hepatocyte growth factor receptor activity	Hepatocyte growth factor receptor	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
lipid binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase HCK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase HCK	Homo sapiens (human)
protein kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein tyrosine kinase activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet activating factor receptor activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor beta-receptor activity	Platelet-derived growth factor receptor beta	Homo sapiens (human)
signaling receptor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor receptor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
ATP binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
enzyme binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
protein kinase binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
vascular endothelial growth factor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
platelet-derived growth factor binding	Platelet-derived growth factor receptor beta	Homo sapiens (human)
monooxygenase activity	Cytochrome P450 2D6	Homo sapiens (human)
iron ion binding	Cytochrome P450 2D6	Homo sapiens (human)
oxidoreductase activity	Cytochrome P450 2D6	Homo sapiens (human)
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	Cytochrome P450 2D6	Homo sapiens (human)
heme binding	Cytochrome P450 2D6	Homo sapiens (human)
anandamide 8,9 epoxidase activity	Cytochrome P450 2D6	Homo sapiens (human)
anandamide 11,12 epoxidase activity	Cytochrome P450 2D6	Homo sapiens (human)
anandamide 14,15 epoxidase activity	Cytochrome P450 2D6	Homo sapiens (human)
protein kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein kinase C binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
signaling receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
insulin receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
integrin binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ATP binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
phospholipase activator activity	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
enzyme binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
heme binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
nuclear estrogen receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
SH2 domain binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
phospholipase binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
transmembrane transporter binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cadherin binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ephrin receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ATPase binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
phosphoprotein binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
BMP receptor binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
connexin binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
scaffold protein binding	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
protein kinase activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor alpha-receptor activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor receptor binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
ATP binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
vascular endothelial growth factor binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein homodimerization activity	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein-containing complex binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
platelet-derived growth factor binding	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein kinase activity	Protein kinase C alpha type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
calcium,diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
integrin binding	Protein kinase C alpha type	Homo sapiens (human)
protein binding	Protein kinase C alpha type	Homo sapiens (human)
ATP binding	Protein kinase C alpha type	Homo sapiens (human)
zinc ion binding	Protein kinase C alpha type	Homo sapiens (human)
enzyme binding	Protein kinase C alpha type	Homo sapiens (human)
histone H3T6 kinase activity	Protein kinase C alpha type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C alpha type	Homo sapiens (human)
diacylglycerol binding	Protein kinase C alpha type	Homo sapiens (human)
protein kinase activity	Protein kinase C eta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C eta type	Homo sapiens (human)
diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	Protein kinase C eta type	Homo sapiens (human)
protein binding	Protein kinase C eta type	Homo sapiens (human)
ATP binding	Protein kinase C eta type	Homo sapiens (human)
enzyme binding	Protein kinase C eta type	Homo sapiens (human)
small GTPase binding	Protein kinase C eta type	Homo sapiens (human)
metal ion binding	Protein kinase C eta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C eta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C eta type	Homo sapiens (human)
protein tyrosine kinase activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
integrin binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
protein binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
ATP binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
coreceptor activity	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
growth factor binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
vascular endothelial growth factor binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
identical protein binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cadherin binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
Hsp90 protein binding	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
protein tyrosine kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cytokine receptor activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
vascular endothelial growth factor receptor activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
ATP binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
nuclear glucocorticoid receptor binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein-containing complex binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
phosphatidylinositol 3-kinase activator activity	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
growth factor binding	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein phosphatase binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein kinase A catalytic subunit binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
identical protein binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
metal ion binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
proline-rich region binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein tyrosine kinase binding	Tyrosine-protein kinase CSK	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase CSK	Homo sapiens (human)
protein kinase activity	Protein kinase C iota type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C iota type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C iota type	Homo sapiens (human)
protein binding	Protein kinase C iota type	Homo sapiens (human)
ATP binding	Protein kinase C iota type	Homo sapiens (human)
phospholipid binding	Protein kinase C iota type	Homo sapiens (human)
metal ion binding	Protein kinase C iota type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C iota type	Homo sapiens (human)
phosphotyrosine residue binding	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
protein binding	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
protein tyrosine kinase activity	Tyrosine-protein kinase Blk	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Tyrosine-protein kinase Blk	Homo sapiens (human)
protein binding	Tyrosine-protein kinase Blk	Homo sapiens (human)
ATP binding	Tyrosine-protein kinase Blk	Homo sapiens (human)
signaling receptor binding	Tyrosine-protein kinase Blk	Homo sapiens (human)
actin monomer binding	Protein kinase C epsilon type	Homo sapiens (human)
protein kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
protein binding	Protein kinase C epsilon type	Homo sapiens (human)
ATP binding	Protein kinase C epsilon type	Homo sapiens (human)
enzyme activator activity	Protein kinase C epsilon type	Homo sapiens (human)
enzyme binding	Protein kinase C epsilon type	Homo sapiens (human)
signaling receptor activator activity	Protein kinase C epsilon type	Homo sapiens (human)
ethanol binding	Protein kinase C epsilon type	Homo sapiens (human)
metal ion binding	Protein kinase C epsilon type	Homo sapiens (human)
14-3-3 protein binding	Protein kinase C epsilon type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C epsilon type	Homo sapiens (human)
protein kinase activity	Angiopoietin-1 receptor	Homo sapiens (human)
transmembrane receptor protein tyrosine kinase activity	Angiopoietin-1 receptor	Homo sapiens (human)
protein binding	Angiopoietin-1 receptor	Homo sapiens (human)
ATP binding	Angiopoietin-1 receptor	Homo sapiens (human)
growth factor binding	Angiopoietin-1 receptor	Homo sapiens (human)
signaling receptor activity	Angiopoietin-1 receptor	Homo sapiens (human)
identical protein binding	Angiopoietin-1 receptor	Homo sapiens (human)
protein kinase activity	Protein kinase C theta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C theta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C theta type	Homo sapiens (human)
protein binding	Protein kinase C theta type	Homo sapiens (human)
ATP binding	Protein kinase C theta type	Homo sapiens (human)
metal ion binding	Protein kinase C theta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C theta type	Homo sapiens (human)
protein kinase activity	Protein kinase C zeta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C zeta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C zeta type	Homo sapiens (human)
protein binding	Protein kinase C zeta type	Homo sapiens (human)
ATP binding	Protein kinase C zeta type	Homo sapiens (human)
potassium channel regulator activity	Protein kinase C zeta type	Homo sapiens (human)
protein kinase binding	Protein kinase C zeta type	Homo sapiens (human)
phospholipase binding	Protein kinase C zeta type	Homo sapiens (human)
insulin receptor substrate binding	Protein kinase C zeta type	Homo sapiens (human)
protein-containing complex binding	Protein kinase C zeta type	Homo sapiens (human)
metal ion binding	Protein kinase C zeta type	Homo sapiens (human)
14-3-3 protein binding	Protein kinase C zeta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C zeta type	Homo sapiens (human)
protein kinase activity	Protein kinase C delta type	Homo sapiens (human)
protein serine/threonine kinase activity	Protein kinase C delta type	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Protein kinase C delta type	Homo sapiens (human)
diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	Protein kinase C delta type	Homo sapiens (human)
non-membrane spanning protein tyrosine kinase activity	Protein kinase C delta type	Homo sapiens (human)
protein binding	Protein kinase C delta type	Homo sapiens (human)
ATP binding	Protein kinase C delta type	Homo sapiens (human)
enzyme activator activity	Protein kinase C delta type	Homo sapiens (human)
enzyme binding	Protein kinase C delta type	Homo sapiens (human)
protein kinase binding	Protein kinase C delta type	Homo sapiens (human)
insulin receptor substrate binding	Protein kinase C delta type	Homo sapiens (human)
metal ion binding	Protein kinase C delta type	Homo sapiens (human)
protein serine kinase activity	Protein kinase C delta type	Homo sapiens (human)
protein serine/threonine kinase activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
diacylglycerol-dependent serine/threonine kinase activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
protein kinase C binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
protein binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
ATP binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
kinase activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
heat shock protein binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
identical protein binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
metal ion binding	Serine/threonine-protein kinase D1	Homo sapiens (human)
protein serine kinase activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
phosphatidylinositol 3-kinase activator activity	Serine/threonine-protein kinase D1	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Ceullar Components (120)

Process	via Protein(s)	Taxonomy
nucleoplasm	Serine/threonine-protein kinase D3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D3	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase D3	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D3	Homo sapiens (human)
extracellular space	Interferon beta	Homo sapiens (human)
extracellular region	Interferon beta	Homo sapiens (human)
nucleus	Protein kinase C gamma type	Homo sapiens (human)
cytosol	Protein kinase C gamma type	Homo sapiens (human)
plasma membrane	Protein kinase C gamma type	Homo sapiens (human)
cell-cell junction	Protein kinase C gamma type	Homo sapiens (human)
postsynaptic density	Protein kinase C gamma type	Homo sapiens (human)
dendrite	Protein kinase C gamma type	Homo sapiens (human)
calyx of Held	Protein kinase C gamma type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C gamma type	Homo sapiens (human)
synaptic membrane	Protein kinase C gamma type	Homo sapiens (human)
presynaptic cytosol	Protein kinase C gamma type	Homo sapiens (human)
postsynaptic cytosol	Protein kinase C gamma type	Homo sapiens (human)
nucleus	Protein kinase C beta type	Homo sapiens (human)
nucleoplasm	Protein kinase C beta type	Homo sapiens (human)
cytoplasm	Protein kinase C beta type	Homo sapiens (human)
centrosome	Protein kinase C beta type	Homo sapiens (human)
cytosol	Protein kinase C beta type	Homo sapiens (human)
plasma membrane	Protein kinase C beta type	Homo sapiens (human)
brush border membrane	Protein kinase C beta type	Homo sapiens (human)
calyx of Held	Protein kinase C beta type	Homo sapiens (human)
extracellular exosome	Protein kinase C beta type	Homo sapiens (human)
presynaptic cytosol	Protein kinase C beta type	Homo sapiens (human)
spectrin	Protein kinase C beta type	Homo sapiens (human)
nuclear envelope	Insulin receptor	Homo sapiens (human)
nuclear lumen	Insulin receptor	Homo sapiens (human)
lysosome	Insulin receptor	Homo sapiens (human)
late endosome	Insulin receptor	Homo sapiens (human)
plasma membrane	Insulin receptor	Homo sapiens (human)
caveola	Insulin receptor	Homo sapiens (human)
external side of plasma membrane	Insulin receptor	Homo sapiens (human)
endosome membrane	Insulin receptor	Homo sapiens (human)
membrane	Insulin receptor	Homo sapiens (human)
dendrite membrane	Insulin receptor	Homo sapiens (human)
neuronal cell body membrane	Insulin receptor	Homo sapiens (human)
extracellular exosome	Insulin receptor	Homo sapiens (human)
insulin receptor complex	Insulin receptor	Homo sapiens (human)
receptor complex	Insulin receptor	Homo sapiens (human)
plasma membrane	Insulin receptor	Homo sapiens (human)
axon	Insulin receptor	Homo sapiens (human)
pericentriolar material	Tyrosine-protein kinase Lck	Homo sapiens (human)
immunological synapse	Tyrosine-protein kinase Lck	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Lck	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lck	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Lck	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Lck	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lck	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendrite	Tyrosine-protein kinase Fyn	Homo sapiens (human)
nucleus	Tyrosine-protein kinase Fyn	Homo sapiens (human)
mitochondrion	Tyrosine-protein kinase Fyn	Homo sapiens (human)
endosome	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Fyn	Homo sapiens (human)
actin filament	Tyrosine-protein kinase Fyn	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
postsynaptic density	Tyrosine-protein kinase Fyn	Homo sapiens (human)
dendrite	Tyrosine-protein kinase Fyn	Homo sapiens (human)
perikaryon	Tyrosine-protein kinase Fyn	Homo sapiens (human)
cell body	Tyrosine-protein kinase Fyn	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Fyn	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase Fyn	Homo sapiens (human)
perinuclear endoplasmic reticulum	Tyrosine-protein kinase Fyn	Homo sapiens (human)
glial cell projection	Tyrosine-protein kinase Fyn	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Tyrosine-protein kinase Fyn	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Fyn	Homo sapiens (human)
mitochondrial matrix	Cyclin-dependent kinase 1	Homo sapiens (human)
chromosome, telomeric region	Cyclin-dependent kinase 1	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
nucleoplasm	Cyclin-dependent kinase 1	Homo sapiens (human)
mitochondrion	Cyclin-dependent kinase 1	Homo sapiens (human)
endoplasmic reticulum membrane	Cyclin-dependent kinase 1	Homo sapiens (human)
centrosome	Cyclin-dependent kinase 1	Homo sapiens (human)
cytosol	Cyclin-dependent kinase 1	Homo sapiens (human)
spindle microtubule	Cyclin-dependent kinase 1	Homo sapiens (human)
membrane	Cyclin-dependent kinase 1	Homo sapiens (human)
midbody	Cyclin-dependent kinase 1	Homo sapiens (human)
extracellular exosome	Cyclin-dependent kinase 1	Homo sapiens (human)
mitotic spindle	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin A1-CDK1 complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin A2-CDK1 complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin B1-CDK1 complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cyclin-dependent protein kinase holoenzyme complex	Cyclin-dependent kinase 1	Homo sapiens (human)
cytoplasm	Cyclin-dependent kinase 1	Homo sapiens (human)
nucleus	Cyclin-dependent kinase 1	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
nucleus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase Lyn	Homo sapiens (human)
lysosomal membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase Lyn	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Lyn	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
adherens junction	Tyrosine-protein kinase Lyn	Homo sapiens (human)
mitochondrial crista	Tyrosine-protein kinase Lyn	Homo sapiens (human)
endocytic vesicle membrane	Tyrosine-protein kinase Lyn	Homo sapiens (human)
intracellular membrane-bounded organelle	Tyrosine-protein kinase Lyn	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase Lyn	Homo sapiens (human)
perinuclear region of cytoplasm	Tyrosine-protein kinase Lyn	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase Lyn	Homo sapiens (human)
glutamatergic synapse	Tyrosine-protein kinase Lyn	Homo sapiens (human)
postsynaptic specialization, intracellular component	Tyrosine-protein kinase Lyn	Homo sapiens (human)
integrin alpha2-beta1 complex	Tyrosine-protein kinase Lyn	Homo sapiens (human)
extracellular region	Hepatocyte growth factor receptor	Homo sapiens (human)
plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
basal plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
cell surface	Hepatocyte growth factor receptor	Homo sapiens (human)
membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
postsynapse	Hepatocyte growth factor receptor	Homo sapiens (human)
basal plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
plasma membrane	Hepatocyte growth factor receptor	Homo sapiens (human)
receptor complex	Hepatocyte growth factor receptor	Homo sapiens (human)
actin filament	Tyrosine-protein kinase HCK	Homo sapiens (human)
nucleus	Tyrosine-protein kinase HCK	Homo sapiens (human)
lysosome	Tyrosine-protein kinase HCK	Homo sapiens (human)
Golgi apparatus	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase HCK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase HCK	Homo sapiens (human)
caveola	Tyrosine-protein kinase HCK	Homo sapiens (human)
focal adhesion	Tyrosine-protein kinase HCK	Homo sapiens (human)
cytoplasmic side of plasma membrane	Tyrosine-protein kinase HCK	Homo sapiens (human)
transport vesicle	Tyrosine-protein kinase HCK	Homo sapiens (human)
cell projection	Tyrosine-protein kinase HCK	Homo sapiens (human)
intracellular membrane-bounded organelle	Tyrosine-protein kinase HCK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase HCK	Homo sapiens (human)
nucleus	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cytoplasm	Platelet-derived growth factor receptor beta	Homo sapiens (human)
Golgi apparatus	Platelet-derived growth factor receptor beta	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
focal adhesion	Platelet-derived growth factor receptor beta	Homo sapiens (human)
membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
apical plasma membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
cytoplasmic vesicle	Platelet-derived growth factor receptor beta	Homo sapiens (human)
lysosomal lumen	Platelet-derived growth factor receptor beta	Homo sapiens (human)
intracellular membrane-bounded organelle	Platelet-derived growth factor receptor beta	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor beta	Homo sapiens (human)
receptor complex	Platelet-derived growth factor receptor beta	Homo sapiens (human)
mitochondrion	Cytochrome P450 2D6	Homo sapiens (human)
endoplasmic reticulum	Cytochrome P450 2D6	Homo sapiens (human)
endoplasmic reticulum membrane	Cytochrome P450 2D6	Homo sapiens (human)
cytoplasm	Cytochrome P450 2D6	Homo sapiens (human)
intracellular membrane-bounded organelle	Cytochrome P450 2D6	Homo sapiens (human)
podosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
nucleoplasm	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cytoplasm	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
mitochondrion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
mitochondrial inner membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
lysosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
late endosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cytosol	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
actin filament	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
caveola	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
focal adhesion	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
cell junction	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
ruffle membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
neuronal cell body	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
dendritic growth cone	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
membrane raft	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
perinuclear region of cytoplasm	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
extracellular exosome	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
synaptic membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
glutamatergic synapse	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
postsynaptic specialization, intracellular component	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
dendritic filopodium	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
plasma membrane	Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)
nucleus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
nucleoplasm	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cytoplasm	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
endoplasmic reticulum membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
Golgi apparatus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
microvillus	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cilium	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
external side of plasma membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
cell junction	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
protein-containing complex	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
receptor complex	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
plasma membrane	Platelet-derived growth factor receptor alpha	Homo sapiens (human)
ciliary basal body	Protein kinase C alpha type	Homo sapiens (human)
nucleoplasm	Protein kinase C alpha type	Homo sapiens (human)
cytoplasm	Protein kinase C alpha type	Homo sapiens (human)
mitochondrion	Protein kinase C alpha type	Homo sapiens (human)
endoplasmic reticulum	Protein kinase C alpha type	Homo sapiens (human)
cytosol	Protein kinase C alpha type	Homo sapiens (human)
plasma membrane	Protein kinase C alpha type	Homo sapiens (human)
mitochondrial membrane	Protein kinase C alpha type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C alpha type	Homo sapiens (human)
extracellular exosome	Protein kinase C alpha type	Homo sapiens (human)
alphav-beta3 integrin-PKCalpha complex	Protein kinase C alpha type	Homo sapiens (human)
cytoplasm	Protein kinase C eta type	Homo sapiens (human)
cytosol	Protein kinase C eta type	Homo sapiens (human)
plasma membrane	Protein kinase C eta type	Homo sapiens (human)
cell-cell junction	Protein kinase C eta type	Homo sapiens (human)
extracellular exosome	Protein kinase C eta type	Homo sapiens (human)
extracellular region	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
nucleus	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endosome	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
early endosome	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endoplasmic reticulum	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
Golgi apparatus	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
external side of plasma membrane	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
cell junction	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
membrane raft	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
anchoring junction	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
sorting endosome	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
plasma membrane	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
receptor complex	Vascular endothelial growth factor receptor 2	Homo sapiens (human)
endoplasmic reticulum	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
endoplasmic reticulum lumen	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
plasma membrane	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
endosome membrane	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
receptor complex	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
plasma membrane	Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase CSK	Homo sapiens (human)
cytosol	Tyrosine-protein kinase CSK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase CSK	Homo sapiens (human)
cell-cell junction	Tyrosine-protein kinase CSK	Homo sapiens (human)
extracellular exosome	Tyrosine-protein kinase CSK	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase CSK	Homo sapiens (human)
Golgi membrane	Protein kinase C iota type	Homo sapiens (human)
nucleus	Protein kinase C iota type	Homo sapiens (human)
nucleoplasm	Protein kinase C iota type	Homo sapiens (human)
endosome	Protein kinase C iota type	Homo sapiens (human)
cytosol	Protein kinase C iota type	Homo sapiens (human)
plasma membrane	Protein kinase C iota type	Homo sapiens (human)
brush border	Protein kinase C iota type	Homo sapiens (human)
bicellular tight junction	Protein kinase C iota type	Homo sapiens (human)
microtubule cytoskeleton	Protein kinase C iota type	Homo sapiens (human)
apical plasma membrane	Protein kinase C iota type	Homo sapiens (human)
cell leading edge	Protein kinase C iota type	Homo sapiens (human)
Schmidt-Lanterman incisure	Protein kinase C iota type	Homo sapiens (human)
intercellular bridge	Protein kinase C iota type	Homo sapiens (human)
extracellular exosome	Protein kinase C iota type	Homo sapiens (human)
tight junction	Protein kinase C iota type	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Protein kinase C iota type	Homo sapiens (human)
glutamatergic synapse	Protein kinase C iota type	Homo sapiens (human)
PAR polarity complex	Protein kinase C iota type	Homo sapiens (human)
membrane raft	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
extrinsic component of cytoplasmic side of plasma membrane	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
immunological synapse	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cytoplasm	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cytosol	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cell-cell junction	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
T cell receptor complex	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase ZAP-70	Homo sapiens (human)
cytosol	Tyrosine-protein kinase Blk	Homo sapiens (human)
plasma membrane	Tyrosine-protein kinase Blk	Homo sapiens (human)
Golgi apparatus	Protein kinase C epsilon type	Homo sapiens (human)
nucleus	Protein kinase C epsilon type	Homo sapiens (human)
cytoplasm	Protein kinase C epsilon type	Homo sapiens (human)
mitochondrion	Protein kinase C epsilon type	Homo sapiens (human)
endoplasmic reticulum	Protein kinase C epsilon type	Homo sapiens (human)
cytosol	Protein kinase C epsilon type	Homo sapiens (human)
plasma membrane	Protein kinase C epsilon type	Homo sapiens (human)
intracellular membrane-bounded organelle	Protein kinase C epsilon type	Homo sapiens (human)
intermediate filament cytoskeleton	Protein kinase C epsilon type	Homo sapiens (human)
synapse	Protein kinase C epsilon type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C epsilon type	Homo sapiens (human)
cell periphery	Protein kinase C epsilon type	Homo sapiens (human)
stress fiber	Angiopoietin-1 receptor	Homo sapiens (human)
actin filament	Angiopoietin-1 receptor	Homo sapiens (human)
extracellular region	Angiopoietin-1 receptor	Homo sapiens (human)
cytoplasm	Angiopoietin-1 receptor	Homo sapiens (human)
plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
microvillus	Angiopoietin-1 receptor	Homo sapiens (human)
cell-cell junction	Angiopoietin-1 receptor	Homo sapiens (human)
focal adhesion	Angiopoietin-1 receptor	Homo sapiens (human)
basal plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
cell surface	Angiopoietin-1 receptor	Homo sapiens (human)
basolateral plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
apical plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
centriolar satellite	Angiopoietin-1 receptor	Homo sapiens (human)
membrane raft	Angiopoietin-1 receptor	Homo sapiens (human)
plasma membrane	Angiopoietin-1 receptor	Homo sapiens (human)
receptor complex	Angiopoietin-1 receptor	Homo sapiens (human)
immunological synapse	Protein kinase C theta type	Homo sapiens (human)
cytosol	Protein kinase C theta type	Homo sapiens (human)
plasma membrane	Protein kinase C theta type	Homo sapiens (human)
aggresome	Protein kinase C theta type	Homo sapiens (human)
centriolar satellite	Protein kinase C theta type	Homo sapiens (human)
stress fiber	Protein kinase C zeta type	Homo sapiens (human)
nuclear envelope	Protein kinase C zeta type	Homo sapiens (human)
cytoplasm	Protein kinase C zeta type	Homo sapiens (human)
endosome	Protein kinase C zeta type	Homo sapiens (human)
microtubule organizing center	Protein kinase C zeta type	Homo sapiens (human)
cytosol	Protein kinase C zeta type	Homo sapiens (human)
plasma membrane	Protein kinase C zeta type	Homo sapiens (human)
cell-cell junction	Protein kinase C zeta type	Homo sapiens (human)
bicellular tight junction	Protein kinase C zeta type	Homo sapiens (human)
postsynaptic density	Protein kinase C zeta type	Homo sapiens (human)
membrane	Protein kinase C zeta type	Homo sapiens (human)
apical plasma membrane	Protein kinase C zeta type	Homo sapiens (human)
nuclear matrix	Protein kinase C zeta type	Homo sapiens (human)
cell junction	Protein kinase C zeta type	Homo sapiens (human)
cell leading edge	Protein kinase C zeta type	Homo sapiens (human)
vesicle	Protein kinase C zeta type	Homo sapiens (human)
myelin sheath abaxonal region	Protein kinase C zeta type	Homo sapiens (human)
axon hillock	Protein kinase C zeta type	Homo sapiens (human)
apical cortex	Protein kinase C zeta type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C zeta type	Homo sapiens (human)
extracellular exosome	Protein kinase C zeta type	Homo sapiens (human)
tight junction	Protein kinase C zeta type	Homo sapiens (human)
Schaffer collateral - CA1 synapse	Protein kinase C zeta type	Homo sapiens (human)
glutamatergic synapse	Protein kinase C zeta type	Homo sapiens (human)
PAR polarity complex	Protein kinase C zeta type	Homo sapiens (human)
extracellular region	Protein kinase C delta type	Homo sapiens (human)
nucleus	Protein kinase C delta type	Homo sapiens (human)
nucleoplasm	Protein kinase C delta type	Homo sapiens (human)
cytoplasm	Protein kinase C delta type	Homo sapiens (human)
mitochondrion	Protein kinase C delta type	Homo sapiens (human)
endoplasmic reticulum	Protein kinase C delta type	Homo sapiens (human)
cytosol	Protein kinase C delta type	Homo sapiens (human)
plasma membrane	Protein kinase C delta type	Homo sapiens (human)
cell-cell junction	Protein kinase C delta type	Homo sapiens (human)
nuclear matrix	Protein kinase C delta type	Homo sapiens (human)
azurophil granule lumen	Protein kinase C delta type	Homo sapiens (human)
endolysosome	Protein kinase C delta type	Homo sapiens (human)
perinuclear region of cytoplasm	Protein kinase C delta type	Homo sapiens (human)
extracellular exosome	Protein kinase C delta type	Homo sapiens (human)
autophagosome membrane	Serine/threonine-protein kinase D1	Homo sapiens (human)
nucleus	Serine/threonine-protein kinase D1	Homo sapiens (human)
trans-Golgi network	Serine/threonine-protein kinase D1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D1	Homo sapiens (human)
plasma membrane	Serine/threonine-protein kinase D1	Homo sapiens (human)
cell-cell junction	Serine/threonine-protein kinase D1	Homo sapiens (human)
cell cortex	Serine/threonine-protein kinase D1	Homo sapiens (human)
Z disc	Serine/threonine-protein kinase D1	Homo sapiens (human)
perinuclear region of cytoplasm	Serine/threonine-protein kinase D1	Homo sapiens (human)
Golgi apparatus	Serine/threonine-protein kinase D1	Homo sapiens (human)
cytosol	Serine/threonine-protein kinase D1	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Assay ID	Title	Year	Journal	Article
AID1796232	Homogeneous Time-resolved Fluorescence (HTRF) Assay from Article 10.1016/s0960-894x(02)00196-8: \\Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck - a selectivity insight.\\	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck -- a selectivity insight.
AID1346987	P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1296008	Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening	2020	SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1	Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening.
AID1346986	P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen	2019	Molecular pharmacology, 11, Volume: 96, Issue:5	A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
AID1347160	Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID1347159	Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay	2020	Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49	Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
AID493040	Navigating the Kinome	2011	Nature chemical biology, Apr, Volume: 7, Issue:4	Navigating the kinome.
AID224282	Inhibition of human p56 Lyn tyrosine kinase	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID223984	Inhibition of human p56 Lck tyrosine kinase	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck -- a selectivity insight.
AID1366201	Inhibition of recombinant human C-terminal FLT3 ITD mutant (571 to 993 residues) after 90 mins by mobility shift assay	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Identification of pyrrolo[2,3-d]pyrimidines as potent HCK and FLT3-ITD dual inhibitors.
AID1487298	Inhibition of HCK (75 to 526 residues) (unknown origin) expressed in Sf9 insect cells after 120 mins	2017	Bioorganic & medicinal chemistry, 08-15, Volume: 25, Issue:16	Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
AID38030	Inhibition of human B lymphoid tyrosine kinase	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID209361	Inhibition of TIE-2 kinase	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck -- a selectivity insight.
AID55200	Inhibition of human Csk tyrosine kinase	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID205333	Inhibition of Src protein tyrosine kinase	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck -- a selectivity insight.
AID132118	Tested in vivo for inhibition ofTCR stimulated (alpha-CD3 mAb) IL-2 production in mice after oral dosing	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck -- a selectivity insight.
AID1407822	Inhibition of Fyn (unknown origin) using Src-family kinase bisamide rhodamine 110 peptide substrate after 1 hr by fluorescence assay	2018	European journal of medicinal chemistry, Sep-05, Volume: 157	Pyrrolopyrimidines: An update on recent advancements in their medicinal attributes.
AID1366202	Inhibition of recombinant human HCK SH3-SH2-KD (75 to 526 residues) after 20 mins by mobility shift assay	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Identification of pyrrolo[2,3-d]pyrimidines as potent HCK and FLT3-ITD dual inhibitors.
AID748778	Inhibition of LCK (64 to 509 amino acids) (unknown origin) by HTRF assay	2013	Bioorganic & medicinal chemistry letters, May-15, Volume: 23, Issue:10	Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors.
AID205329	Inhibition of Src protein tyrosine kinase	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID1487299	Inhibition of human HCK (81 to 526 residues) expressed in Sf9 insect cells after 120 mins	2017	Bioorganic & medicinal chemistry, 08-15, Volume: 25, Issue:16	Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.
AID748776	Inhibition of TIE2 (unknown origin) by HTRF assay	2013	Bioorganic & medicinal chemistry letters, May-15, Volume: 23, Issue:10	Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors.
AID216640	Inhibition of Vascular endothelial growth factor receptor 2	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID223955	Inhibition of human p56 Lck tyrosine kinase (lck64-509)	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID1366203	Growth inhibition of human MV4-11 cells after 3 days by Alamar blue assay	2017	Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22	Identification of pyrrolo[2,3-d]pyrimidines as potent HCK and FLT3-ITD dual inhibitors.
AID209359	Inhibition of TIE-2 kinase.	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID223948	Inhibition of human p55 Fyn tyrosine kinase.	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID216770	Inhibition of Vascular endothelial growth factor receptor 2	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck -- a selectivity insight.
AID1347411	qHTS to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: primary screen against the NCATS Mechanism Interrogation Plate v5.0 (MIPE) Libary	2020	ACS chemical biology, 07-17, Volume: 15, Issue:7	High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID1347412	qHTS assay to identify inhibitors of the type 1 interferon - major histocompatibility complex class I in skeletal muscle: Counter screen cell viability and HiBit confirmation	2020	ACS chemical biology, 07-17, Volume: 15, Issue:7	High-Throughput Screening to Identify Inhibitors of the Type I Interferon-Major Histocompatibility Complex Class I Pathway in Skeletal Muscle.
AID12176	Area under curve was determined after oral administration at a dose 10 mg/kg to male Sprague-Dawley rats	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID13176	Bioavailability was determined after intravenous administration at a dose 5 mg/kg to male Sprague-Dawley rats	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID112308	Effective dose was evaluated in vivo for the inhibition of IFN-gamma production for 3 days peroral administration of the compound	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID10669	Maximum time constant was determined after oral administration at a dose 10 mg/kg to male Sprague-Dawley rats	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID213575	Inhibition of human Tyrosine-protein kinase CSK	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID51721	Inhibition of Cell division control protein 2, Cdk-1 (Inactive at 1 mM ATP)	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID164946	Inhibition of Protein kinase C (Inactive at 1 mM ATP)	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID161092	Inhibition of Platelet-derived growth factor receptor (Inactive at 1 mM ATP)	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID11493	Volume of distribution was determined after intravenous administration at a dose 5 mg/kg to male Sprague-Dawley rats	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID95445	Inhibition of IL-2 production in anti-CD3 stimulated Jurkat cells	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID10983	Clearance was determined after intravenous administration at a dose 5 mg/kg to male Sprague-Dawley rats	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID11977	Maximum plasma concentration was determined after oral administration at a dose 10 mg/kg to male Sprague-Dawley rats	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID93356	Inhibition of Insulin-like growth factor receptor (Inactive at 1 mM ATP)	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID220178	Inhibition of cMet kinase (Inactive at 1 mM ATP)	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID209358	Inhibition of TIE-2 kinase	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID89226	Inhibition of IL-2 production in whole blood assay	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID91678	Inhibition of insulin receptor kinase (Inactive at 1 mM ATP)	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID220423	Inhibition of Zeta-chain (TCR) associated protein kinase 70kDa, Zap70 (Inactive at 1 mM ATP)	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID10462	Half life period was determined after intravenous administration at a dose 5 mg/kg to male Sprague-Dawley rats	2002	Bioorganic & medicinal chemistry letters, Jun-17, Volume: 12, Issue:12	Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.
AID1803322	In Vitor Src Tyrosine Kinase Activity Assay from Article 10.3109/14756366.2012.715288: \\Synthesis, biological evaluation and docking studies of new pyrrolo[2,3-d] pyrimidine derivatives as Src family-selective tyrosine kinase inhibitors.\\	2013	Journal of enzyme inhibition and medicinal chemistry, Oct, Volume: 28, Issue:5	Synthesis, biological evaluation and docking studies of new pyrrolo[2,3-d] pyrimidine derivatives as Src family-selective tyrosine kinase inhibitors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (21.05)	29.6817
2010's	11 (57.89)	24.3611
2020's	4 (21.05)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (5.26%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	18 (94.74%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
2-cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide [no description available]	2.06	1	hydroxycinnamic acid
n(6),n(6)-dimethyladenine N(6),N(6)-dimethyladenine : A tertiary amine that is adenine substituted at N-6 by geminal methyl groups.	2.06	1	tertiary amine
glimepiride glimepiride: structure given in first source	3.27	1	sulfonamide
go 6976 [no description available]	2.06	1	indolocarbazole; organic heterohexacyclic compound	EC 2.7.11.13 (protein kinase C) inhibitor
gw8510 GW8510: 3' substituted indolone as a scaffold for the development of neuroprotective drug; structure in first source	2.06	1
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide [no description available]	2.06	1	bromobenzenes; isoquinolines; olefinic compound; secondary amino compound; sulfonamide	EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor
fasudil fasudil: intracellular calcium antagonist; structure in first source. fasudil : An isoquinoline substituted by a (1,4-diazepan-1-yl)sulfonyl group at position 5. It is a Rho-kinase inhibitor and its hydrochloride hydrate form is approved for the treatment of cerebral vasospasm and cerebral ischemia.	2.06	1	isoquinolines; N-sulfonyldiazepane	antihypertensive agent; calcium channel blocker; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; geroprotector; neuroprotective agent; nootropic agent; vasodilator agent
nsc 664704 kenpaullone: inhibits CDK1/cyclin B; structure in first source. kenpaullone : An indolobenzazepine that is paullone in which the hydrogen at position 9 is replaced by a bromo substituent. It is an ATP-competitive inhibitor of cyclin-dependent kinases (CDKs) and glycogen synthase kinase 3beta (GSK3beta).	2.06	1	indolobenzazepine; lactam; organobromine compound	cardioprotective agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor; EC 2.7.11.26 (tau-protein kinase) inhibitor; geroprotector
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source	2.06	1	chromones; morpholines; organochlorine compound	autophagy inhibitor; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; geroprotector
olomoucine olomoucine: inhibits protein P34CDC2. olomoucine : A 9H-purine that is substituted by a (2-hydroxyethyl)nitrilo, benzylnitrilo and a methyl group at positions 2,6 and 9, respectively. It is a cyclin-dependent kinase inhibitor.	2.06	1	2,6-diaminopurines; ethanolamines	EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
3,3',4,5'-tetrahydroxystilbene [no description available]	2.06	1	stilbenoid
ag 1879 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo(3,4-d)pyrimidin-4-amine: Fyn kinase inhibitor	4.27	5	aromatic amine; monochlorobenzenes; pyrazolopyrimidine	beta-adrenergic antagonist; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; geroprotector
sb 220025 SB 220025: inhibits p38 mitogen-activated protein kinase; structure in first source. SB220025 : Am member of the class of imidazoles carrying piperidin-4-yl, 4-fluophenyl and 2-aminopyrimidin-4-yl substituents at posiitons 1, 4 and 5 respectively.	2.06	1	aminopyrimidine; imidazoles; organofluorine compound; piperidines	angiogenesis inhibitor; anti-inflammatory agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
sb 239063 SB 239063: structure in first source. SB-239063 : A member of the class of imidazoles carrying 4-hydroxycyclohexyl, 4-fluorophenyl and 2-methoxypyrimidin-4-yl substituents at positions 1, 4 and 5 respectively.	2.06	1	imidazoles
sb 202190 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole: structure given in first source; inhibits p38 MAP kinase	2.06	1	imidazoles; organofluorine compound; phenols; pyridines	apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
imatinib [no description available]	2.06	1	aromatic amine; benzamides; N-methylpiperazine; pyridines; pyrimidines	antineoplastic agent; apoptosis inducer; tyrosine kinase inhibitor
gatifloxacin Gatifloxacin: A fluoroquinolone antibacterial agent and DNA TOPOISOMERASE II inhibitor that is used as an ophthalmic solution for the treatment of BACTERIAL CONJUNCTIVITIS.. gatifloxacin : A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes.	2.06	1	N-arylpiperazine; organofluorine compound; quinolinemonocarboxylic acid; quinolone antibiotic; quinolone	antiinfective agent; antimicrobial agent; EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
cytarabine [no description available]	3.27	1	beta-D-arabinoside; monosaccharide derivative; pyrimidine nucleoside	antimetabolite; antineoplastic agent; antiviral agent; immunosuppressive agent
1,3-diphenylurea 1,3-diphenylurea : A member of the class of phenylureas that is urea in which one of the hydrogens of each amino group is replaced by a phenyl group. It is present in coconut milk (Cocos nucifera).	2.06	1	phenylureas	cytokinin; plant metabolite
pyrroles 1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.	3.47	7	pyrrole; secondary amine
pyrazolanthrone pyrazolanthrone: JNK (c-Jun N-terminal kinase) inhibitor; structure in first source. anthra[1,9-cd]pyrazol-6(2H)-one : A member of the class of anthrapyrazoles that is anthra[1,9-cd]pyrazole substituted at position 6 by an oxo group. An inhibitor of c-Jun N-terminal kinase.	2.06	1	anthrapyrazole; aromatic ketone; cyclic ketone	antineoplastic agent; c-Jun N-terminal kinase inhibitor; geroprotector
hydrazine diamine : Any polyamine that contains two amino groups.	2.1	1	azane; hydrazines	EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
ribavirin Rebetron: Rebetron is tradename	3.27	1	1-ribosyltriazole; aromatic amide; monocarboxylic acid amide; primary carboxamide	anticoronaviral agent; antiinfective agent; antimetabolite; antiviral agent; EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor
norharman norharman: RN given refers to parent cpd. beta-carboline : The parent compound of the beta-carbolines, a tricyclic structure comprising an indole ring system ortho- fused to C-3 and C-4 of a pyridine ring.	2.06	1	beta-carbolines; mancude organic heterotricyclic parent	fungal metabolite; marine metabolite
eupatorin eupatorin: a flavonoid from the East Asian medicinal plant Orthosiphon spicatus; prevents oxidative inactivation of 15-lipoxygenase; structure given in first source. eupatorin : A trimethoxyflavone that is 6-hydroxyluteolin in which the phenolic hydogens at positions 4', 6 and 7 have been replaced by methyl groups.	2.06	1	dihydroxyflavone; polyphenol; trimethoxyflavone	anti-inflammatory agent; antineoplastic agent; apoptosis inducer; Brassica napus metabolite; calcium channel blocker; P450 inhibitor; vasodilator agent
gefitinib [no description available]	2.06	1	aromatic ether; monochlorobenzenes; monofluorobenzenes; morpholines; quinazolines; secondary amino compound; tertiary amino compound	antineoplastic agent; epidermal growth factor receptor antagonist
ns 1608 NS 1608: a BK(Ca) channel opener	2.06	1	ureas
vatalanib [no description available]	2.06	1	monochlorobenzenes; phthalazines; pyridines; secondary amino compound	angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; vascular endothelial growth factor receptor antagonist
birb 796 [no description available]	2.06	1	aromatic ether; morpholines; naphthalenes; pyrazoles; ureas	EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; immunomodulator
sb 203580 [no description available]	2.06	1	imidazoles; monofluorobenzenes; pyridines; sulfoxide	EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor; geroprotector; Hsp90 inhibitor; neuroprotective agent
erlotinib [no description available]	2.06	1	aromatic ether; quinazolines; secondary amino compound; terminal acetylenic compound	antineoplastic agent; epidermal growth factor receptor antagonist; protein kinase inhibitor
orantinib [no description available]	2.06	1	monocarboxylic acid; oxindoles; pyrroles	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; vascular endothelial growth factor receptor antagonist
lapatinib [no description available]	2.06	1	furans; organochlorine compound; organofluorine compound; quinazolines	antineoplastic agent; tyrosine kinase inhibitor
sorafenib [no description available]	2.06	1	(trifluoromethyl)benzenes; aromatic ether; monochlorobenzenes; phenylureas; pyridinecarboxamide	angiogenesis inhibitor; anticoronaviral agent; antineoplastic agent; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; ferroptosis inducer; tyrosine kinase inhibitor
n-(4-methoxybenzyl)-n'-(5-nitro-1,3-thiazol-2-yl)urea N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea: structure in first source	2.06	1
4-(4-(4-chloro-phenyl)thiazol-2-ylamino)phenol [no description available]	2.06	1	substituted aniline
3-amino-n-(4-methoxybenzyl)-4,6-dimethylthieno(2,3-b)pyridine-2-carboxamide 3-amino-N-(4-methoxybenzyl)-4,6-dimethylthieno(2,3-b)pyridine-2-carboxamide: structure in first source	2.06	1
cct018159 CCT018159: structure in first source. CCT-018159 : A member of the class of pyrazoles that is 1H-pyrazole carrying 1,4-benzodioxane-6-yl and 5-ethyl-2,4-dihydroxyphenyl substituents at positions 4 and 5 respectively.	2.06	1	benzodioxine; pyrazoles; resorcinols	antineoplastic agent; apoptosis inducer; Hsp90 inhibitor
bms 387032 N-(5-(((5-(1,1-dimethylethyl)-2-oxazolyl)methyl)thio)-2-thiazolyl)-4-piperidinecarboxamide: a CDK2 inhibitor with antineoplastic activity; structure in first source. N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of piperidine-4-carboxylic acid with the amino group of 5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-amine. It is an ATP-competitive inhibitor of CDK2, CDK7 and CDK9 kinases and exhibits anti-cancer properties.	2.06	1	1,3-oxazoles; 1,3-thiazoles; organic sulfide; piperidinecarboxamide; secondary carboxamide	angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
tandutinib [no description available]	2.06	1	aromatic ether; N-arylpiperazine; N-carbamoylpiperazine; phenylureas; piperidines; quinazolines; tertiary amino compound	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
vx-745 [no description available]	2.06	1	aryl sulfide; dichlorobenzene; difluorobenzene; pyrimidopyridazine	anti-inflammatory drug; apoptosis inducer; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
dasatinib N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)-1,3-thiazole-5-carboxamide: a dasatinib prodrug; structure in first source. dasatinib (anhydrous) : An aminopyrimidine that is 2-methylpyrimidine which is substituted at position 4 by the primary amino group of 2-amino-1,3-thiazole-5-carboxylic acid and at position 6 by a 4-(2-hydroxyethyl)piperazin-1-yl group, and in which the carboxylic acid group has been formally condensed with 2-chloro-6-methylaniline to afford the corresponding amide. A multi-targeted kinase inhibitor, it is used, particularly as the monohydrate, for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia. Note that the name 'dasatinib' is used to refer to the monohydrate (USAN) as well as to anhydrous dasatinib (INN).	2.06	1	1,3-thiazoles; aminopyrimidine; monocarboxylic acid amide; N-(2-hydroxyethyl)piperazine; N-arylpiperazine; organochlorine compound; secondary amino compound; tertiary amino compound	anticoronaviral agent; antineoplastic agent; tyrosine kinase inhibitor
zd 6474 CH 331: structure in first source	2.06	1	aromatic ether; organobromine compound; organofluorine compound; piperidines; quinazolines; secondary amine	antineoplastic agent; tyrosine kinase inhibitor
N-methyl-2-[[3-[2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide [no description available]	2.06	1	aryl sulfide
N-[2-(diethylamino)ethyl]-5-[(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide [no description available]	2.06	1	indoles
ver-49009 VER-49009: inhibits heat shock protein 90 molecular chaperone; structure in first source. 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)pyrazole-3-carboxamide : An aromatic amide obtained by formal condensation of the carboxy group of 5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)pyrazole-3-carboxylic acid with the amino group of ethylamine.	2.06	1	aromatic amide; monochlorobenzenes; monomethoxybenzene; pyrazoles; resorcinols	Hsp90 inhibitor
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1h-imidazol-2-yl)benzamide 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide: a TGF-beta type I receptor kinase activity inhibitor	2.06	1	benzamides; benzodioxoles; imidazoles; pyridines	EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
alsterpaullone alsterpaullone: structure in first source. alsterpaullone : An organic heterotetracyclic compound that is 1,3-dihydro-2H-1-benzazepin-2-one which shares its 4-5 bond with the 3-2 bond of 5-nitro-1H-indole.	2.06	1	C-nitro compound; caprolactams; organic heterotetracyclic compound	anti-HIV-1 agent; antineoplastic agent; apoptosis inducer; EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor; EC 2.7.11.26 (tau-protein kinase) inhibitor
imd 0354 N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide: a cardioprotective agent that inhibits IkappaB kinase beta (IKKbeta); structure in first source	2.06	1	benzamides
acacetin 5,7-dihydroxy-4'-methoxyflavone : A monomethoxyflavone that is the 4'-methyl ether derivative of apigenin.	2.06	1	dihydroxyflavone; monomethoxyflavone	anticonvulsant; plant metabolite
cgp 77675 CGP 77675: belongs to class of substituted 5,7-diphenyl-pyrrolo(2,3-d)pyrimidines; structure in first source	3.62	2
pd 166285 [no description available]	2.06	1
palbociclib [no description available]	2.06	1	aminopyridine; aromatic ketone; cyclopentanes; piperidines; pyridopyrimidine; secondary amino compound; tertiary amino compound	antineoplastic agent; EC 2.7.11.22 (cyclin-dependent kinase) inhibitor
jnj-7706621 [no description available]	2.06	1	sulfonamide
2-tert-butyl-9-fluoro-3,6-dihydro-7h-benz(h)imidazo(4,5-f)isoquinoline-7-one 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one: a janus-activated kinase inhibitor. 2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one : An organic heterotetracyclic compound that is 1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one bearing additional tert-butyl and fluoro substituents at positions 2 and 9 respectively.	2.06	1	organic heterotetracyclic compound; organofluorine compound	EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
vx680 [no description available]	2.06	1	N-arylpiperazine
cyc 116 4-methyl-5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)thiazol-2-amine: an aurora kinase inhibitor; structure in first source	2.06	1
1-azakenpaullone 1-azakenpaullone : An organic heterotetracyclic compound that is 7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indole substituted at positions 6 and 9 by oxo and bromo groups respectively.	2.06	1	lactam; organic heterotetracyclic compound; organobromine compound; organonitrogen heterocyclic compound	EC 2.7.11.26 (tau-protein kinase) inhibitor; Wnt signalling activator
gdp 366 GDP 366: an antineoplastic agent; structure in first source	2.06	1
b 43 RK-24466 : A member of the class of pyrrolopyrimidines that is 7H-pyrrolo[2,3-d]pyrimidine substituted by amino, 4-phenoxyphenyl, and cyclopentyl groups at positions 4, 5 and 7, respectively. It is a potent inhibitor of Lck that inhibits Lck (64-509) and LckCD isoforms (IC50 of less than 1 and 2 nM, respectively).	2.01	1	aromatic amine; aromatic ether; cyclopentanes; primary amino compound; pyrrolopyrimidine	EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor; geroprotector
2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-2-purinyl]amino]ethanol [no description available]	2.06	1	thiopurine
a 770041 [no description available]	2.06	1	aromatic amide
cp 547632 3-(4-bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide: inhibits vascular endothelial growth factor receptor-2 tyrosine kinase; structure in first source	2.06	1
bms345541 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline: structure in first source	2.06	1	quinoxaline derivative
adw 742 [no description available]	2.06	1
gw843682x [no description available]	2.06	1	(trifluoromethyl)benzenes
sb 242235 SB 242235: p38 MAP kinase antagonist	2.06	1
pi103 PI103: pyridofuropyrimidine antineoplastic; a potent inhibitor of class I phosphatidylinositide 3-kinases (PI3K); structure in first soruce	2.06	1	aromatic amine; morpholines; organic heterotricyclic compound; phenols; tertiary amino compound	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor
tgx 221 TGX 221: a platelet aggregation inhibitor	2.06	1	pyridopyrimidine
zm 447439 ZM447439 : A member of the class of quinazolines that is quinazoline which is substituted at positions 4, 6 and 7 by a (4-benzamidophenyl)nitrilo group, methoxy group and a 3-(morpholin-4-yl)propoxy group, respectively. It is an ATP-competitive inhibitor of Aurora A and Aurora B kinases with IC50 of 110 nM and 130 nM, respectively.	2.06	1	aromatic ether; benzamides; morpholines; polyether; quinazolines; secondary amino compound; tertiary amino compound	antineoplastic agent; apoptosis inducer; Aurora kinase inhibitor
rucaparib AG14447: Poly(ADP-ribose) polymerase inhibitor; structure in first source	2.06	1	azepinoindole; caprolactams; organofluorine compound; secondary amino compound	antineoplastic agent; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor
cediranib [no description available]	2.06	1	aromatic ether
tae226 TAE226: an adhesion kinase inhibitor, offers an attractive therapeutic approach in ovarian carcinoma; structure in first source	2.06	1	morpholines
tak-715 N-(4-(2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)-2-pyridyl)benzamide: anti-rheumatoid arthritis agent; structure in first source	2.06	1	benzamides
chir 99021 Chir 99021: structure in first source. CHIR 99021 : A member of the class of aminopyrimidines that is 2-aminopyrimidine substituted at positions N2, 5 and 6 by (5-cyanopyridin-2-yl)ethyl, 4-methylimidazol-2-yl and 2,4-dichlorophenyl groups respectively.	2.06	1	aminopyridine; aminopyrimidine; cyanopyridine; diamine; dichlorobenzene; imidazoles; secondary amino compound	EC 2.7.11.26 (tau-protein kinase) inhibitor
ly2090314 LY-2090314 : A member of the class of diazepinoindoles that is 1,2,3,4-tetrahydro[1,4]diazepino[6,7,1-hi]indole substituted by piperidin-1-ylcarbonyl, 4-(imidazo[1,2-a]pyridin-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl and fluoro groups at position 2, 7 and 9, respectively. It is a potent ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50 values of 1.5 nM and 0.9 nM for GSK-3alpha and GSK-3beta. The drug is in clinical development for the treatment of advanced/metastatic cancer.	2.06	1	diazepinoindole; imidazopyridine; maleimides; monofluorobenzenes; piperidinecarboxamide; ureas	antineoplastic agent; apoptosis inducer; EC 2.7.11.26 (tau-protein kinase) inhibitor; Wnt signalling activator
pazopanib pazopanib: a protein kinase inhibitor. pazopanib : A pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer.	2.06	1	aminopyrimidine; indazoles; sulfonamide	angiogenesis modulating agent; antineoplastic agent; tyrosine kinase inhibitor; vascular endothelial growth factor receptor antagonist
bay 61-3606 [no description available]	2.06	1	pyrimidines
sotrastaurin sotrastaurin: a potent protein kinase C-selective inhibitor; structure in first source. sotrastaurin : A member of the class of maleimides that is maleimide which is substituted at position 3 by an indol-3-yl group and at position 4 by a quinazolin-4-yl group, which in turn is substituted at position 2 by a 4-methylpiperazin-1-yl group. It is a potent and selective inhibitor of protein kinase C and has been investigated as an immunosuppresant in renal transplant patients.	2.06	1	indoles; maleimides; N-alkylpiperazine; N-arylpiperazine; quinazolines	anticoronaviral agent; EC 2.7.11.13 (protein kinase C) inhibitor; immunosuppressive agent
vx 702 VX 702: a p38 MAP kinase inhibitor	2.06	1	phenylpyridine
6-[[5-fluoro-2-(3,4,5-trimethoxyanilino)-4-pyrimidinyl]amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one [no description available]	2.06	1	methoxybenzenes; substituted aniline
cvt-6883 3-ethyl-1-propyl-8-(1-(3-trifluoromethylbenzyl)-1H-pyrazol-4-yl)-3,7-dihydropurine-2,6-dione: structure in first source	2.06	1
r 1487 [no description available]	2.06	1
nvp-ast487 NVP-AST487: antineoplastic; a RET kinase inhibitor that blocks growth and calcitonin gene expression through distinct mechanisms in medullary thyroid cancer cells	2.06	1
abt 869 [no description available]	2.06	1	aromatic amine; indazoles; phenylureas	angiogenesis inhibitor; antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
azd 1152 AZD-1152 : A member of the of quinazolines that is 4-aminoquinazolin-7-ol in which the amino group at position 4 has been substituted by a 5-[2-(3-fluoroanilino)-2-oxoethyl]-1H-pyrazol-3-yl group, while the hydroxy group at position 7 has been converted into the corresponding 3-[ethyl(2-hydroxyethyl)aminopropyl ether.	2.06	1	anilide; monoalkyl phosphate; monofluorobenzenes; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor; prodrug
3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine 3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)pyrazol-4-yl]pyridin-2-amine : A pyrazolylpiperidine that consists of 4-(pyrazol-1-yl)piperidine carrying a 2-amino-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-5-yl group at the 4-position of the pyrazole ring.. rac-crizotinib : A racemate comprising equimolar amounts of (R)- and (S)-crizotinib. The active (R)-enantiomer acts as a kinase inhibitor and is used for the treatment of patients with locally advanced or metastatic non-small cell lung cancer.	2.06	1	aminopyridine; aromatic ether; dichlorobenzene; organofluorine compound; pyrazolylpiperidine; racemate	antineoplastic agent; biomarker; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
gw 2580 5-(3-methoxy-4-((4-methoxybenzyl)oxy)benzyl)pyrimidine-2,4-diamine: a cFMS kinase inhibitor; structure in first source	2.06	1
osi 906 [no description available]	2.06	1	cyclobutanes; quinolines
mln8054 [no description available]	2.06	1	benzazepine
pf-562,271 [no description available]	2.06	1	indoles
pha 767491 PHA 767491: a Cdc7 inhibitor; structure in first source	2.06	1	pyrrolopyridine
gpi 15427 [no description available]	2.06	1
dactolisib dactolisib: antineoplastic agent that inhibits both phosphatidylinositol 3-kinase and mTOR. dactolisib : An imidazoquinoline that is 3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinoline substituted at position 1 by a 4-(1-cyanoisopropyl)phenyl group and at position 8 by a quinolin-3-yl group. A dual PI3K/mTOR inhibitor used in cancer treatment.	2.06	1	imidazoquinoline; nitrile; quinolines; ring assembly; ureas	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; mTOR inhibitor
a-484954 A-484954: eEF2K inhibitor; structure in first source	2.06	1
azd 1152-hqpa AZD2811: has antineoplastic activity; structure in first source	2.06	1	anilide; monofluorobenzenes; primary alcohol; pyrazoles; quinazolines; secondary amino compound; secondary carboxamide; tertiary amino compound	antineoplastic agent; Aurora kinase inhibitor
nvp-tae684 [no description available]	2.06	1	piperidines
gsk 269962a [no description available]	2.06	1
3-[(1-methyl-3-indolyl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one [no description available]	2.06	1	indoles
tg101209 [no description available]	2.06	1	N-alkylpiperazine; N-arylpiperazine; pyrimidines; secondary amino compound; sulfonamide	antineoplastic agent; apoptosis inducer; EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor
pf 04217903 [no description available]	2.06	1	quinolines
3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1-pyrazolyl]propanenitrile [no description available]	2.06	1	pyrrolopyrimidine
gdc 0941 pictrelisib : A sulfonamide composed of indazole, morpholine, and methylsulfonyl-substituted piperazine rings bound to a thienopyrimidine ring.	2.06	1	indazoles; morpholines; piperazines; sulfonamide; thienopyrimidine	EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor
ph 797804 PH 797804: an NSAID; structure in first source. PH 797804 : A member of the class of benzamides obtained by formal condensation of the carboxy group of 3-{3-bromo-4-[(2,4-difluorobenzyl)oxy]-6-methyl-2-oxopyridin-1-yl}-4-methylbenzoic acid with the amino group of methylamine.	2.06	1	aromatic ether; benzamides; organobromine compound; organofluorine compound; pyridone	anti-inflammatory agent; EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor
mln 8237 MLN 8237: an aurora kinase A inhibitor	2.06	1	benzazepine
mk-1775 adavosertib: a Wee1 kinase inhibitor; structure in first source	2.06	1	piperazines
PP121 [no description available]	2.06	1	aromatic amine; cyclopentanes; pyrazolopyrimidine; pyrrolopyridine	antineoplastic agent; EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor; tyrosine kinase inhibitor
sns 314 SNS 314: an aurora kinase inhibitor; structure in first source	2.06	1	ureas
entrectinib entrectinib: inhibits TRK, ROS1, and ALK receptor tyrosine kinases; structure in first source. entrectinib : A member of the class of indazoles that is 1H-indazole substituted by [4-(4-methylpiperazin-1-yl)-2-(tetrahydro-2H-pyran-4-ylamino)benzoyl]amino and 3,5-difluorobenzyl groups at positions 3 and 5, respectively. It is a potent inhibitor of TRKA, TRKB, TRKC, ROS1, and ALK (IC50 values of 0.1 to 1.7 nM), and used for the treatment of NTRK, ROS1 and ALK gene fusion-positive solid tumours.	2.06	1	benzamides; difluorobenzene; indazoles; N-methylpiperazine; oxanes; secondary amino compound; secondary carboxamide	antibacterial agent; antineoplastic agent; apoptosis inducer; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor
abt-348 ilorasertib: an antineoplastic agent and protein kinase inhibitor; structure in first source	2.06	1
chir 258 [no description available]	2.06	1
r 1530 [no description available]	2.06	1
2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1h-indole-5-carbonitrile 2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1H-indole-5-carbonitrile: structure in first source. AZD1080 : A member of the class of hydroxyindoles that is 1H-indole substituted by hydroxy, 5-(morpholin-4-ylmethyl)pyridin-2-yl, and cyano groups at positions 2, 3 and 5, respectively. It is a potent, brain permeable inhibitor of human GSK3alpha and GSK3beta with Ki of 6.9 nM and 31 nM, respectively. The drug was being developed by AstraZeneca for the treatment of Alzheimer's disease (clinical trial now discontinued).	2.06	1	hydroxyindoles; morpholines; nitrile; pyridines; tertiary amino compound	antineoplastic agent; apoptosis inducer; EC 2.7.11.26 (tau-protein kinase) inhibitor; tau aggregation inhibitor

Condition	Relationship Strength	Studies
Benign Neoplasms [description not available]	2.08	1
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	2.08	1
Acute Myelogenous Leukemia [description not available]	2.58	2
Leukemia, Myeloid, Acute Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.	2.58	2
Cancer of Prostate [description not available]	3.09	1
HIV Coinfection [description not available]	3.09	1
Prostatic Neoplasms Tumors or cancer of the PROSTATE.	3.09	1
HIV Infections Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS).	3.09	1
Congenital Zika Syndrome [description not available]	2.25	1
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	2.25	1
Zika Virus Infection A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME.	2.25	1
Bone Loss, Osteoclastic [description not available]	2.25	1
Innate Inflammatory Response [description not available]	2.25	1
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	2.25	1
Cancer of Pancreas [description not available]	2.1	1
Invasiveness, Neoplasm [description not available]	2.1	1
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).	2.1	1
Granulocytic Leukemia, Chronic [description not available]	2.43	2
Leukemia, Myelogenous, Chronic, BCR-ABL Positive Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.	2.43	2
Cell Transformation, Neoplastic Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.	2.01	1
Di Guglielmo Disease [description not available]	2.01	1
Leukemia, Erythroblastic, Acute A myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.	2.01	1

a 419259

Cross-References

Synonyms (44)

Research Excerpts

Bioavailability

Protein Targets (32)

Potency Measurements

Inhibition Measurements

Biological Processes (686)

Molecular Functions (122)

Ceullar Components (120)

Bioassays (50)

Research

Studies (19)

Market Indicators

Research Demand Index: 17.23

Study Types

a 419259

Cross-References

Synonyms (44)

Research Excerpts

Bioavailability

Protein Targets (32)

Potency Measurements

Inhibition Measurements

Biological Processes (686)

Molecular Functions (122)

Ceullar Components (120)

Bioassays (50)

Research

Studies (19)

Market Indicators

Research Demand Index: 17.23

Study Types

Related Drugs (113)

Related Conditions (22)