1-phenylazo-2-naphthylamine profile

1-phenylazo-2-naphthylamine (Sudan I) is an **azo dye** with the chemical formula C₁₆H₁₃N₃.

**Here's why it's important in research:**

* **Biological Staining:** Sudan I is a **lipophilic dye**, meaning it has an affinity for fats and oils. This property makes it useful in **biological research for staining lipids** in tissues and cells.
* **Microscopy:** It's used to visualize fat droplets, cell membranes, and other lipid-rich structures under a microscope.
* **Histological staining:** Sudan I helps researchers differentiate between various tissues based on their lipid content.
* **Chemical Analysis:** Its color-changing properties are useful in chemical analysis, particularly in:
* **Spectrophotometry:** The intensity of Sudan I's color can be measured to quantify the amount of lipids in a sample.
* **Titration:** It can be used as an indicator in titrations involving lipid-based reactions.
* **Model System:** Sudan I is often used as a model system for studying **dye-substrate interactions**, which is relevant in areas like:
* **Drug delivery:** Understanding how dyes interact with biological molecules can help in designing targeted drug delivery systems.
* **Bioimaging:** Sudan I's properties can be used to develop new imaging techniques for studying cellular processes.

**Important Notes:**

* **Toxicity:** Sudan I has been classified as a **possible human carcinogen**, so it should be handled with caution in the lab.
* **Alternative Dyes:** Many alternative dyes are available for lipid staining, with varying degrees of toxicity and specificity.

In conclusion, 1-phenylazo-2-naphthylamine (Sudan I) is a valuable tool in biological and chemical research. Its properties make it useful for staining, analyzing, and understanding lipid-based processes, but its potential toxicity requires careful consideration.

ID Source	ID
PubMed CID	6824
CHEMBL ID	86177
CHEMBL ID	1734418
CHEBI ID	82554
SCHEMBL ID	295204
SCHEMBL ID	295205
MeSH ID	M0128134

Synonym
CHEMBL86177
chebi:82554 ,
ccris 3193
brn 1842536
zlut rozpoustedlova 5 [czech]
ci solvent yellow 5
hsdb 1041
ci 11380
af yellow no. 2
a.f. yellow no. 2
1-benzene-azo-beta-naphthylamine
zlut maselna ab [czech]
1-(phenylazo)naphthalen-2-amine
ai3-09035
1-phenylazo-2-naphthylamine
nsc 11228
solvent yellow 5
ext d and c yellow no. 9
einecs 201-636-3
azo benzene 1-naphthalene, 2'-amino-
1-benzeneazo-2-naphthylamine
1-(phenylazo)-2-naphthalenamine
1-benzeneazo-.beta.-naphthylamine
85-84-7
a.f. yellow no.2
fd & c yellow 3
grasal yellow
nsc11228
c.i. 11380
2-naphthylamine, 1-(phenylazo)-
jaune ab
c.i. solvent yellow 5
mls002638198 ,
cerisol yellow ab
yellow ab
1-(phenylazo)-2-naphthylamine
dolkwal yellow ab
c.i. food yellow 10
yellow no. 2
fd and c yellow no. 3
nsc-11228
wln: l66j bnunr& cz
2-naphthalenamine, 1-(phenylazo)-
smr001547687
1-phenyldiazenylnaphthalen-2-amine
AKOS004120651
C19552
1-(2-phenyldiazenyl)-2-naphthalenamine
HMS3080K05
zlut rozpoustedlova 5
3vsi4d701x ,
2-naphthalenamine, 1-(2-phenyldiazenyl)-
zlut maselna ab
unii-3vsi4d701x
FT-0608255
ki404
c.i. food yellow 10 [hsdb]
yellow ab [iarc]
1-(phenylazo)-2-naphthylamine [ii]
fd&c yellow no. 3 (delisted)
yellow ab [mi]
ki404 [inci]
SCHEMBL295204
SCHEMBL295205
AKOS016037985
1-phenylazonaphthalen-2-amine
DTXSID0058932
CHEMBL1734418
1-(phenyldiazenyl)-2-naphthalenamine #
KLCDQSGLLRINHY-UHFFFAOYSA-N
(e)-1-(phenyldiazenyl)naphthalen-2-amine
(e)-1-(phenylazo)-2-naphthylamine
Q27156064
1-(phenyldiazenyl)naphthalen-2-amine
Q26841219

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Chain A, JmjC domain-containing histone demethylation protein 3A	Homo sapiens (human)	Potency	12.5893	0.6310	35.7641	100.0000	AID504339
acid sphingomyelinase	Homo sapiens (human)	Potency	89.1251	14.1254	24.0613	39.8107	AID504937
Nrf2	Homo sapiens (human)	Potency	3.5481	0.0920	8.2222	23.1093	AID624171
glp-1 receptor, partial	Homo sapiens (human)	Potency	11.2202	0.0184	6.8060	14.1254	AID624417
TDP1 protein	Homo sapiens (human)	Potency	16.4687	0.0008	11.3822	44.6684	AID686978; AID686979
Smad3	Homo sapiens (human)	Potency	12.5893	0.0052	7.8098	29.0929	AID588855
apical membrane antigen 1, AMA1	Plasmodium falciparum 3D7	Potency	17.7828	0.7079	12.1943	39.8107	AID720542
67.9K protein	Vaccinia virus	Potency	3.5481	0.0001	8.4406	100.0000	AID720579
chromobox protein homolog 1	Homo sapiens (human)	Potency	12.5893	0.0060	26.1688	89.1251	AID540317
nuclear factor erythroid 2-related factor 2 isoform 2	Homo sapiens (human)	Potency	10.3225	0.0041	9.9848	25.9290	AID504444
flap endonuclease 1	Homo sapiens (human)	Potency	89.1251	0.1337	25.4129	89.1251	AID588795
geminin	Homo sapiens (human)	Potency	29.0929	0.0046	11.3741	33.4983	AID624296
Vpr	Human immunodeficiency virus 1	Potency	63.0957	1.5849	19.6264	63.0957	AID651644
Glycoprotein hormones alpha chain	Homo sapiens (human)	Potency	28.1838	4.4668	8.3448	10.0000	AID624291
TAR DNA-binding protein 43	Homo sapiens (human)	Potency	22.3872	1.7783	16.2081	35.4813	AID652104
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
G protein-coupled receptor signaling pathway	Glycoprotein hormones alpha chain	Homo sapiens (human)
positive regulation of cell population proliferation	Glycoprotein hormones alpha chain	Homo sapiens (human)
hormone-mediated signaling pathway	Glycoprotein hormones alpha chain	Homo sapiens (human)
regulation of signaling receptor activity	Glycoprotein hormones alpha chain	Homo sapiens (human)
positive regulation of steroid biosynthetic process	Glycoprotein hormones alpha chain	Homo sapiens (human)
positive regulation of cell migration	Glycoprotein hormones alpha chain	Homo sapiens (human)
thyroid gland development	Glycoprotein hormones alpha chain	Homo sapiens (human)
luteinizing hormone secretion	Glycoprotein hormones alpha chain	Homo sapiens (human)
organ growth	Glycoprotein hormones alpha chain	Homo sapiens (human)
follicle-stimulating hormone signaling pathway	Glycoprotein hormones alpha chain	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Glycoprotein hormones alpha chain	Homo sapiens (human)
negative regulation of organ growth	Glycoprotein hormones alpha chain	Homo sapiens (human)
follicle-stimulating hormone secretion	Glycoprotein hormones alpha chain	Homo sapiens (human)
thyroid hormone generation	Glycoprotein hormones alpha chain	Homo sapiens (human)
negative regulation of protein phosphorylation	TAR DNA-binding protein 43	Homo sapiens (human)
mRNA processing	TAR DNA-binding protein 43	Homo sapiens (human)
RNA splicing	TAR DNA-binding protein 43	Homo sapiens (human)
negative regulation of gene expression	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of protein stability	TAR DNA-binding protein 43	Homo sapiens (human)
positive regulation of insulin secretion	TAR DNA-binding protein 43	Homo sapiens (human)
response to endoplasmic reticulum stress	TAR DNA-binding protein 43	Homo sapiens (human)
positive regulation of protein import into nucleus	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of circadian rhythm	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of apoptotic process	TAR DNA-binding protein 43	Homo sapiens (human)
negative regulation by host of viral transcription	TAR DNA-binding protein 43	Homo sapiens (human)
rhythmic process	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of cell cycle	TAR DNA-binding protein 43	Homo sapiens (human)
3'-UTR-mediated mRNA destabilization	TAR DNA-binding protein 43	Homo sapiens (human)
3'-UTR-mediated mRNA stabilization	TAR DNA-binding protein 43	Homo sapiens (human)
nuclear inner membrane organization	TAR DNA-binding protein 43	Homo sapiens (human)
amyloid fibril formation	TAR DNA-binding protein 43	Homo sapiens (human)
regulation of gene expression	TAR DNA-binding protein 43	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
hormone activity	Glycoprotein hormones alpha chain	Homo sapiens (human)
protein binding	Glycoprotein hormones alpha chain	Homo sapiens (human)
follicle-stimulating hormone activity	Glycoprotein hormones alpha chain	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
double-stranded DNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
RNA binding	TAR DNA-binding protein 43	Homo sapiens (human)
mRNA 3'-UTR binding	TAR DNA-binding protein 43	Homo sapiens (human)
protein binding	TAR DNA-binding protein 43	Homo sapiens (human)
lipid binding	TAR DNA-binding protein 43	Homo sapiens (human)
identical protein binding	TAR DNA-binding protein 43	Homo sapiens (human)
pre-mRNA intronic binding	TAR DNA-binding protein 43	Homo sapiens (human)
molecular condensate scaffold activity	TAR DNA-binding protein 43	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
extracellular region	Glycoprotein hormones alpha chain	Homo sapiens (human)
extracellular space	Glycoprotein hormones alpha chain	Homo sapiens (human)
Golgi lumen	Glycoprotein hormones alpha chain	Homo sapiens (human)
follicle-stimulating hormone complex	Glycoprotein hormones alpha chain	Homo sapiens (human)
pituitary gonadotropin complex	Glycoprotein hormones alpha chain	Homo sapiens (human)
extracellular space	Glycoprotein hormones alpha chain	Homo sapiens (human)
intracellular non-membrane-bounded organelle	TAR DNA-binding protein 43	Homo sapiens (human)
nucleus	TAR DNA-binding protein 43	Homo sapiens (human)
nucleoplasm	TAR DNA-binding protein 43	Homo sapiens (human)
perichromatin fibrils	TAR DNA-binding protein 43	Homo sapiens (human)
mitochondrion	TAR DNA-binding protein 43	Homo sapiens (human)
cytoplasmic stress granule	TAR DNA-binding protein 43	Homo sapiens (human)
nuclear speck	TAR DNA-binding protein 43	Homo sapiens (human)
interchromatin granule	TAR DNA-binding protein 43	Homo sapiens (human)
nucleoplasm	TAR DNA-binding protein 43	Homo sapiens (human)
chromatin	TAR DNA-binding protein 43	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (17)

Assay ID	Title	Year	Journal	Article
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635	Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID1745845	Primary qHTS for Inhibitors of ATXN expression
AID167940	Tested for carcinogenic activity on breast after oral administration of the compound; - denotes non carcinogenic activity.	1981	Journal of medicinal chemistry, Mar, Volume: 24, Issue:3	Computer-assisted structure-activity studies of chemical carcinogens. Aromatic amines.
AID168112	Carcinogenic activity after oral administration	1981	Journal of medicinal chemistry, Mar, Volume: 24, Issue:3	Computer-assisted structure-activity studies of chemical carcinogens. Aromatic amines.
AID167951	Carcinogenic activity on ear duct after oral administration of the compound; - denotes non carcinogenic activity.	1981	Journal of medicinal chemistry, Mar, Volume: 24, Issue:3	Computer-assisted structure-activity studies of chemical carcinogens. Aromatic amines.
AID168101	Carcinogenic activity on mixed data after oral administration	1981	Journal of medicinal chemistry, Mar, Volume: 24, Issue:3	Computer-assisted structure-activity studies of chemical carcinogens. Aromatic amines.
AID167928	Carcinogenic activity on all sites after oral administration	1981	Journal of medicinal chemistry, Mar, Volume: 24, Issue:3	Computer-assisted structure-activity studies of chemical carcinogens. Aromatic amines.
AID168085	Carcinogenic activity on liver after oral administration of the compound	1981	Journal of medicinal chemistry, Mar, Volume: 24, Issue:3	Computer-assisted structure-activity studies of chemical carcinogens. Aromatic amines.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	4 (44.44)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (22.22)	29.6817
2010's	2 (22.22)	24.3611
2020's	1 (11.11)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
2-aminofluorene [no description available]	1.96	1
amitrole Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.. amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.	1.96	1	aromatic amine; triazoles	carotenoid biosynthesis inhibitor; EC 1.11.1.6 (catalase) inhibitor; herbicide
3-methylcholanthrene Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.. 3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.	1.96	1	ortho- and peri-fused polycyclic arene	aryl hydrocarbon receptor agonist; carcinogenic agent
azathioprine Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed). azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.	1.96	1	aryl sulfide; C-nitro compound; imidazoles; thiopurine	antimetabolite; antineoplastic agent; carcinogenic agent; DNA synthesis inhibitor; hepatotoxic agent; immunosuppressive agent; prodrug
suramin Suramin: A polyanionic compound with an unknown mechanism of action. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. (From AMA Drug Evaluations Annual, 1992, p1643) It has also been shown to have potent antineoplastic properties.. suramin : A member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years.	1.96	1	naphthalenesulfonic acid; phenylureas; secondary carboxamide	angiogenesis inhibitor; antinematodal drug; antineoplastic agent; apoptosis inhibitor; EC 2.7.11.13 (protein kinase C) inhibitor; GABA antagonist; GABA-gated chloride channel antagonist; purinergic receptor P2 antagonist; ryanodine receptor agonist; trypanocidal drug
n-hydroxy-2-aminofluorene N-hydroxy-2-aminofluorene: structure	1.96	1
hydroxyacetylaminofluorene Hydroxyacetylaminofluorene: A N-hydroxylated derivative of 2-ACETYLAMINOFLUORENE that has demonstrated carcinogenic action.	1.96	1	2-acetamidofluorenes
2-acetylaminofluorene 2-Acetylaminofluorene: A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the aryl hydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.	1.96	1	2-acetamidofluorenes	antimitotic; carcinogenic agent; epitope; mutagen
p-aminoazobenzene p-Aminoazobenzene: Used in the form of its salts as a dye and as an intermediate in manufacture of Acid Yellow, diazo dyes, and indulines.. 4-(phenylazo)aniline : Azobenzene substituted at one of the 4-positions by an amino group. It has a role as a dye and an allergen.	1.96	1
2-naphthylamine 2-Naphthylamine: A naphthalene derivative with carcinogenic action.. 2-naphthylamine : A naphthylamine carrying the amino group at position 2.	7.35	2	naphthylamine	carcinogenic agent
3,3'-dichlorobenzidine 3,3'-Dichlorobenzidine: A material used in the manufacture of azo dyes that is toxic to skin and carcinogenic in several species.	1.96	1	biphenyls; monochlorobenzenes; organochlorine compound
4-biphenylamine 4-biphenylamine: used in detection of sulfates, & as a carcinogen in cancer research; RN given refers to parent cpd; structure. biphenyl-4-amine : An aminobiphenyl that is biphenyl substituted by an amino group at position 4.	1.96	1	aminobiphenyl	carcinogenic agent
benzidine benzidine: RN given refers to parent cpd. benzidine : A member of the class of biphenyls that is 1,1'-biphenyl in which the hydrogen at the para-position of each phenyl group has been replaced by an amino group.	1.96	1	biphenyls; substituted aniline	carcinogenic agent
o-aminoazotoluene o-Aminoazotoluene: An azo dye with carcinogenic properties.	1.96	1
methylenebis(chloroaniline) Methylenebis(chloroaniline): Aromatic diamine used in the plastics industry as curing agent for epoxy resins and urethane rubbers. It causes bladder, liver, lung, and other neoplasms.. 4,4'-methylene-bis-(2-chloroaniline) : A chloroaniline that consists of two 2-chloroaniline units joined by a methylene bridge.	1.96	1	chloroaniline	metabolite
4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane: RN given refers to parent cpd; structure. 4,4'-diaminodiphenylmethane : An aromatic amine that is diphenylmethane substituted at the 4-position of each benzene ring by an amino group.	1.96	1	aromatic amine	allergen; carcinogenic agent
2-tolidine 2-tolidine: RN given refers to parent cpd; structure	1.96	1	biphenyls
yellow ob [no description available]	7.63	3
2-naphthol 2-naphthol: RN given refers to parent cpd. 2-naphthol : A naphthol carrying a hydroxy group at position 2.. naphthols : Any hydroxynaphthalene derivative that has a single hydroxy substituent.	1.96	1	naphthol	antinematodal drug; genotoxin; human urinary metabolite; human xenobiotic metabolite; mouse metabolite; radical scavenger
2,7-diacetylaminofluorene 2,7-diacetylaminofluorene: has been found to induce leukemia in animals; minor descriptor (75-84); on-line search 2-ACETYLAMINOFLUORENE/AA (75-84); Index Medicus search 2-ACETYLAMINOFLUORENE/AA (80-82), FLUORENES (75-79)	1.96	1
2,7-fluorenediamine 2,7-fluorenediamine: peroxidase reagent for blood smears; RN given refers to parent cpd	1.96	1
n-hydroxy-1-naphthylamine N-hydroxy-1-naphthylamine: carcinogen	1.96	1	N-substituted amine
1-aminoanthracene [no description available]	1.96	1	anthracenamine
2-anthramine 2-anthramine: structure	1.96	1	anthracenamine
4,4'-methylene bis(2-methylaniline) 4,4'-methylene bis(2-methylaniline): structure	1.96	1	diarylmethane
1-phenylazo-2-naphthol 1-phenylazo-2-naphthol: RN given refers to cpd without isomeric designation	1.96	1
9-aminophenanthrene [no description available]	1.96	1	phenanthrenamine
3-methoxy-4-aminoazobenzene [no description available]	1.96	1
n-hydroxy-n-(2-fluorenyl)benzamide N-hydroxy-N-(2-fluorenyl)benzamide: structure given in first source	1.96	1
4-acetylaminobiphenyl [no description available]	1.96	1	biphenyls
2-acetamidophenanthrene [no description available]	1.96	1
n-hydroxy-4-acetylaminobiphenyl N-hydroxy-4-acetylaminobiphenyl: structure. N-hydroxy-4-acetylaminobiphenyl : A hydroxamic acid that is biphenyl-4-amine bearing N-hydroxy and N-acetyl substituents.	1.96	1	hydroxamic acid
acetoxyacetylaminofluorene Acetoxyacetylaminofluorene: An alkylating agent that forms DNA ADDUCTS at the C-8 position in GUANINE, resulting in single strand breaks. It has demonstrated carcinogenic action.. N-acetoxy-2-acetamidofluorene : A 2-acetamidofluorene compound in which the parent 2-acetamidofluorene is substituted on nitrogen by an acetoxy group.	1.96	1	2-acetamidofluorenes	carcinogenic agent; mutagen
3-acetylaminofluorene 3-acetylaminofluorene: non-carcinogenic structural isomer of carcinogen N-2-fluorenylacetamide	1.96	1
2',3-dimethyl-4-aminobiphenyl 2',3-dimethyl-4-aminobiphenyl: RN given refers to parent cpd; structure	1.96	1
fanft FANFT: A potent nitrofuran derivative tumor initiator. It causes bladder tumors in all animals studied and is mutagenic to many bacteria.	1.96	1
N-fluorenylacetamide [no description available]	1.96	1	fluorenes
acridine orange Acridine Orange: A cationic cytochemical stain specific for cell nuclei, especially DNA. It is used as a supravital stain and in fluorescence cytochemistry. It may cause mutations in microorganisms.. acridine orange : Fluorescent dye useful for cell cycle determination. It is cell-permeable, and interacts with DNA and RNA by intercalation or electrostatic attractions respectively.. acridine orange free base : A member of the class of aminoacridines that is acridine carrying two dimethylamino substituents at positions 3 and 6. The hydrochloride salt is the fluorescent dye 'acridine orange', used for cell cycle determination.	1.96	1	aminoacridines; aromatic amine; tertiary amino compound	fluorochrome; histological dye
n-hydroxy-2-naphthylamine [no description available]	1.96	1
n-acetoxy-4-acetylaminobiphenyl [no description available]	1.96	1
7-iodo-n-2-acetylaminofluorene [no description available]	1.96	1
n-hydroxy-4-aminoazobenzene N-hydroxy-4-aminoazobenzene: RN given refers to parent cpd	1.96	1
4-dimethylaminostilbene 4-dimethylaminostilbene: RN given refers to cpd without isomeric designation; structure	1.96	1
4-acetylaminostilbene 4-acetylaminostilbene: RN given refers to non-specified isomer	1.96	1
4-aminostilbene 4-aminostilbene: RN given refers to cpd without isomeric designation	1.96	1
nefurthiazole nefurthiazole: structure	1.96	1	C-nitro compound; furans
4,4'-diaminostilbene [no description available]	1.96	1

Condition	Indicated	Relationship Strength	Studies	Trials
Innate Inflammatory Response [description not available]	0	2.05	1	0
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	0	2.05	1	0

1-phenylazo-2-naphthylamine

Cross-References

Synonyms (75)

Protein Targets (15)

Potency Measurements

Biological Processes (32)

Molecular Functions (12)

Ceullar Components (14)

Bioassays (17)

Research

Studies (9)

Market Indicators

Research Demand Index: 11.83

Study Types

1-phenylazo-2-naphthylamine

Cross-References

Synonyms (75)

Protein Targets (15)

Potency Measurements

Biological Processes (32)

Molecular Functions (12)

Ceullar Components (14)

Bioassays (17)

Research

Studies (9)

Market Indicators

Research Demand Index: 11.83

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Related Drugs (47)

Related Conditions (2)